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UY28102A1 - NEW SALTS - Google Patents

NEW SALTS

Info

Publication number
UY28102A1
UY28102A1 UY28102A UY28102A UY28102A1 UY 28102 A1 UY28102 A1 UY 28102A1 UY 28102 A UY28102 A UY 28102A UY 28102 A UY28102 A UY 28102A UY 28102 A1 UY28102 A1 UY 28102A1
Authority
UY
Uruguay
Prior art keywords
new salts
thrombin
alkyl
anticoagulants
thrombosis
Prior art date
Application number
UY28102A
Other languages
Spanish (es)
Inventor
Matti Ahlqvist
Martin Bohlin
Tord Inghardt
Anita L Lundblad
Carl-Gustav Sigfridsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to UY28102A priority Critical patent/UY28102A1/en
Publication of UY28102A1 publication Critical patent/UY28102A1/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se proporcionan sales de adición de ácido farmacéuticamente aceptables de compuestos de fórmula I, en donde R1 representa alquilo C1-2 sustituido por uno o más sustituyentes fluoro; R2 representa alquilo C1-2; y n representa 0, 1 ó 2, las cuales son útiles como profármacos de inhibidores competitivos de proteasas similares a la tripsina, tales como la trombina y, de esta forma, en particular, en el tratamiento de afecciones en las que es necesario inhibir la trombina (por ej. trombosis) o como anticoagulantes.Pharmaceutically acceptable acid addition salts of compounds of formula I are provided, wherein R1 represents C1-2 alkyl substituted by one or more fluoro substituents; R2 represents C1-2 alkyl; and n represents 0, 1 or 2, which are useful as prodrugs of competitive inhibitors of trypsin-like proteases, such as thrombin and, in this way, in particular, in the treatment of conditions in which it is necessary to inhibit thrombin (eg thrombosis) or as anticoagulants.

UY28102A 2003-11-27 2003-11-27 NEW SALTS UY28102A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
UY28102A UY28102A1 (en) 2003-11-27 2003-11-27 NEW SALTS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
UY28102A UY28102A1 (en) 2003-11-27 2003-11-27 NEW SALTS

Publications (1)

Publication Number Publication Date
UY28102A1 true UY28102A1 (en) 2005-06-30

Family

ID=38812852

Family Applications (1)

Application Number Title Priority Date Filing Date
UY28102A UY28102A1 (en) 2003-11-27 2003-11-27 NEW SALTS

Country Status (1)

Country Link
UY (1) UY28102A1 (en)

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Legal Events

Date Code Title Description
DESI Application deemed to be withdrawn

Effective date: 20120307