UY28805A1 - Derivados de 1,6-naftiridina y 1,8-naftiridina y su uso par tratar la diabetes y trastornos relacionados - Google Patents
Derivados de 1,6-naftiridina y 1,8-naftiridina y su uso par tratar la diabetes y trastornos relacionadosInfo
- Publication number
- UY28805A1 UY28805A1 UY28805A UY28805A UY28805A1 UY 28805 A1 UY28805 A1 UY 28805A1 UY 28805 A UY28805 A UY 28805A UY 28805 A UY28805 A UY 28805A UY 28805 A1 UY28805 A1 UY 28805A1
- Authority
- UY
- Uruguay
- Prior art keywords
- naftiridine
- derivatives
- related disorders
- treat diabetes
- naphthyridine
- Prior art date
Links
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 150000005054 naphthyridines Chemical class 0.000 abstract 2
- VSOSXKMEQPYESP-UHFFFAOYSA-N 1,6-naphthyridine Chemical compound C1=CN=CC2=CC=CN=C21 VSOSXKMEQPYESP-UHFFFAOYSA-N 0.000 abstract 1
- 150000005058 1,8-naphthyridines Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
Landscapes
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
La invención se refiere, en general, a derivados de naftiridina de fórmula donde uno de U, X, Y y Z es nitrógeno y los otros son C-R, donde R es hidrógeno o un sustituyente. Más específicamente, la invención se refiere a derivados de 1,6-naftiridina y 1,8-naftiridina y a composiciones farmacéuticas que contienen tales derivados. Los métodos de la invención comprenden la administración de un derivado de naftiridina de la invención para el tratamiento de la diabetes y trastornos relacionados.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55297104P | 2004-03-12 | 2004-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY28805A1 true UY28805A1 (es) | 2005-09-30 |
Family
ID=35056657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY28805A UY28805A1 (es) | 2004-03-12 | 2005-03-11 | Derivados de 1,6-naftiridina y 1,8-naftiridina y su uso par tratar la diabetes y trastornos relacionados |
Country Status (6)
| Country | Link |
|---|---|
| AR (1) | AR048088A1 (es) |
| GT (1) | GT200500049A (es) |
| PE (1) | PE20060332A1 (es) |
| TW (1) | TW200538124A (es) |
| UY (1) | UY28805A1 (es) |
| WO (1) | WO2005091857A2 (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009015917A2 (en) * | 2007-05-14 | 2009-02-05 | F. Hoffmann-La Roche Ag | Dihydroquinone and dihydronaphthridine inhibitors of jnk |
| PT2448938E (pt) | 2009-06-29 | 2014-07-31 | Incyte Corp | Pirimidinonas como inibidoras de pi3k |
| FR2952934B1 (fr) * | 2009-11-23 | 2012-06-22 | Sanofi Aventis | Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique |
| WO2011075643A1 (en) | 2009-12-18 | 2011-06-23 | Incyte Corporation | Substituted heteroaryl fused derivatives as pi3k inhibitors |
| WO2011130342A1 (en) | 2010-04-14 | 2011-10-20 | Incyte Corporation | FUSED DERIVATIVES AS ΡI3Κδ INHIBITORS |
| US9062055B2 (en) | 2010-06-21 | 2015-06-23 | Incyte Corporation | Fused pyrrole derivatives as PI3K inhibitors |
| EP2612669A4 (en) | 2010-08-31 | 2014-05-14 | Snu R&Db Foundation | USING THE FÖTAL REPROGRAMMING OF A PPAR AGONIST |
| JP5961187B2 (ja) | 2010-12-20 | 2016-08-02 | インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ | Ｐｉ３ｋ阻害剤としてのｎ−（１−（置換フェニル）エチル）−９ｈ−プリン−６−アミン |
| US9108984B2 (en) | 2011-03-14 | 2015-08-18 | Incyte Corporation | Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors |
| US9126948B2 (en) | 2011-03-25 | 2015-09-08 | Incyte Holdings Corporation | Pyrimidine-4,6-diamine derivatives as PI3K inhibitors |
| RU2629111C2 (ru) * | 2011-07-12 | 2017-08-24 | Ф.Хоффманн-Ля Рош Аг | Аминометилхинолоны, полезные при лечении jnk-опосредованного расстройства |
| EP3196202B1 (en) | 2011-09-02 | 2019-02-27 | Incyte Holdings Corporation | Heterocyclylamines as pi3k inhibitors |
| AR090548A1 (es) | 2012-04-02 | 2014-11-19 | Incyte Corp | Azaheterociclobencilaminas biciclicas como inhibidores de pi3k |
| US10077277B2 (en) | 2014-06-11 | 2018-09-18 | Incyte Corporation | Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors |
| PL3262046T3 (pl) | 2015-02-27 | 2021-05-04 | Incyte Corporation | Sole inhibitora pi3k i sposoby ich wytwarzania |
| WO2016183060A1 (en) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Process for the synthesis of a phosphoinositide 3-kinase inhibitor |
| WO2016183063A1 (en) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Crystalline forms of a pi3k inhibitor |
| WO2018102885A1 (en) * | 2016-12-09 | 2018-06-14 | Bionomics Limited | Modulators of nicotinic acetylcholine receptors and uses thereof |
| KR102884803B1 (ko) | 2018-06-01 | 2025-11-12 | 인사이트 코포레이션 | Pi3k 관련 장애의 치료를 위한 투여 요법 |
| JOP20180097B1 (ar) * | 2018-10-22 | 2023-03-28 | Univ Of Jordan | مشتقات 1.8 - نفثاريدين الغلايكوزيلية و طرق تحضيرها و استخدامها في معالجة الالتهابات الميكروبية |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL51092A0 (en) * | 1976-12-10 | 1977-02-28 | Abic Ltd | Naphthyridine derivatives and their preparation |
| US4767762A (en) * | 1985-12-23 | 1988-08-30 | Abbott Laboratories | Tricyclic quinoline and naphthyride antibacterials |
-
2005
- 2005-02-24 WO PCT/US2005/005367 patent/WO2005091857A2/en not_active Ceased
- 2005-03-10 AR ARP050100921A patent/AR048088A1/es unknown
- 2005-03-11 GT GT200500049A patent/GT200500049A/es unknown
- 2005-03-11 PE PE2005000284A patent/PE20060332A1/es not_active Application Discontinuation
- 2005-03-11 UY UY28805A patent/UY28805A1/es not_active Application Discontinuation
- 2005-03-11 TW TW094107389A patent/TW200538124A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005091857A3 (en) | 2006-10-05 |
| GT200500049A (es) | 2005-10-24 |
| PE20060332A1 (es) | 2006-06-01 |
| WO2005091857A2 (en) | 2005-10-06 |
| AR048088A1 (es) | 2006-03-29 |
| TW200538124A (en) | 2005-12-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ECSP045084A (es) | Derivados de 1,6-naftiridina y su uso para el tratamiento de la diabetes y trastornos relacionados | |
| UY28805A1 (es) | Derivados de 1,6-naftiridina y 1,8-naftiridina y su uso par tratar la diabetes y trastornos relacionados | |
| AR029815A1 (es) | Derivados aza-indolicos, un proceso para su preparacion, composicion farmaceutica, un metodo para su elaboracion y el uso de dichos derivados para la manufactura de un medicamento | |
| NO20091893L (no) | Nye 1,4-benzotiepin-1,1-dioksidderivater som er substituert med benzylgrupper, fremgangsmater for fremstilling av medisiner inneholdende forbindelsene og anvendelse derav. | |
| UY28150A1 (es) | Agentes terapeuticos | |
| NO20062583L (no) | Difenylazetidinonderivater med kolesterolabsorpsjonsinhiberende aktivitet | |
| NO20055421L (no) | Kinolinderivater som fosfodiestrase-inhibitorer | |
| BRPI0314308B8 (pt) | antagonistas de opióide, seus usos, e composição farmacêutica | |
| UY29246A1 (es) | Nuevos compuestos | |
| ECSP099662A (es) | Nuevos Derivados de 3-([1,2,4]triazolo[4,3-a]piridin-7-il)benzamida | |
| NO20084752L (no) | Konjugater av aziridinayl-epotilonanaloger og farmasoytiske sammensetninger som inneholder disse | |
| NO20082065L (no) | Nye imidazo[4,5-b]pyridinderivater som inhibitorer av glykogensyntasekinase 3 for anvendelse ved behandling av demens og neurodegenerative forstyrrelser | |
| AR063602A1 (es) | Derivados de espiroindolinona, formulaciones farmaceuticas que los contienen y su uso en la obtencion de un medicamento para el tratamiento de trastornos oncologicos. | |
| NO20070224L (no) | 2-karbamid-4-fenyltiazolderivater, fremstilling og terapeutisk anvendelse derav | |
| NO20075082L (no) | Pyridin-3-karboksamidderivater som CB1-inversagonister | |
| NO20071137L (no) | Nye piperidinderivater for behandling av depresjon | |
| NO20062591L (no) | Difenylazetidinonderivater med kolesterolabsorpsjonsinhiberende aktivitet | |
| CO6341631A2 (es) | Derivados de 1,2,4 - oxadiazol y su uso terapéutico | |
| DE602008003322D1 (de) | Pyrrolo (3, 2, 1-ij) chinolin-4-on-derivate zur behandlung von tuberkulose | |
| NO20082496L (no) | Pyrazinderivater | |
| CL2012001027A1 (es) | Compuestos derivados de 7-(fenilamina)-5-oxo-1,2,3,5-tetrahidro-imidazo[1,2-a]piridina, 7-(fenilamina)5-oxo-2,3-dihidro-5h-tiazolo[3,2-a]piridina, 7-(fenulaminas)-5-oxo-2,3-dihidro-2hoxazolo[3,2-a]piridina: composicion farmaceutica; utiles en el tratamiento de enfermedades, trastornos o sindrome asociado con la inhibicion mek. | |
| UY29838A1 (es) | Derivados sustituidos de 4,5,6,7-tetrahidropirrolo(3,2,c)piridin-4-ona y de 4,5-tetrahidropirrolo(3,2,c)piridin-4-ona, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones | |
| DK1703905T3 (da) | Indol-derivater og anvendelse deraf som kinaseinhibitorer, især IKK2-inhibitorer | |
| CY1109366T1 (el) | Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης | |
| NO20055977L (no) | Nye benzimidazolderivater |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 109 | Application deemed to be withdrawn |
Effective date: 20160502 |