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UY26594A1 - Proceso para la simple preparación de (3-cloro-4fluorofenilo)-(7-(3-morfolina-4-ilopropoxi)-6-nitroquinazolna-4ilo)-amina o (3-cloro-4-fluorofenilo)-(7-(3-morfolina-4-il-propoxi)-6-aminoquinazolina-4-ilo)-amina. - Google Patents

Proceso para la simple preparación de (3-cloro-4fluorofenilo)-(7-(3-morfolina-4-ilopropoxi)-6-nitroquinazolna-4ilo)-amina o (3-cloro-4-fluorofenilo)-(7-(3-morfolina-4-il-propoxi)-6-aminoquinazolina-4-ilo)-amina.

Info

Publication number
UY26594A1
UY26594A1 UY26594A UY26594A UY26594A1 UY 26594 A1 UY26594 A1 UY 26594A1 UY 26594 A UY26594 A UY 26594A UY 26594 A UY26594 A UY 26594A UY 26594 A1 UY26594 A1 UY 26594A1
Authority
UY
Uruguay
Prior art keywords
morpholine
amine
chlorine
fluorophenyl
aminoquinazoline
Prior art date
Application number
UY26594A
Other languages
English (en)
Inventor
Dr Huber Barth
Dr Klaus Steiner
Simon Schnerider
Original Assignee
Goedecke Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Goedecke Gmbh filed Critical Goedecke Gmbh
Publication of UY26594A1 publication Critical patent/UY26594A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Esta invención se refiere a una reacción global para la preparación de (3-cloro-4-fluorofenilo)-(7-(3-morfolina-4-ilo-propoxi)-6-nitroquinazolina-4-ilo)-amina (I) o de (3-cloro-4-fluorofenilo)-(7-(3-morfolina-4-ilo-propoxi)-6-aminoquinazolina-4-ilo)-amina.
UY26594A 2000-02-26 2001-02-23 Proceso para la simple preparación de (3-cloro-4fluorofenilo)-(7-(3-morfolina-4-ilopropoxi)-6-nitroquinazolna-4ilo)-amina o (3-cloro-4-fluorofenilo)-(7-(3-morfolina-4-il-propoxi)-6-aminoquinazolina-4-ilo)-amina. UY26594A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10009267A DE10009267A1 (de) 2000-02-26 2000-02-26 Verfahren zur einfachen Herstellung von (3-Chlor-4-fluor-phenyl)-[7-(3-morpholin-4-yl-propoxy)-6-nitro-quinazolin-4-yl]-amin bzw. (3-Chlor-4-fluor-phenyl)-[7-(3-morpholin-4-yl-propoxy)-6-amino-quinazolin-4-yl]-amin

Publications (1)

Publication Number Publication Date
UY26594A1 true UY26594A1 (es) 2001-09-28

Family

ID=7632648

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26594A UY26594A1 (es) 2000-02-26 2001-02-23 Proceso para la simple preparación de (3-cloro-4fluorofenilo)-(7-(3-morfolina-4-ilopropoxi)-6-nitroquinazolna-4ilo)-amina o (3-cloro-4-fluorofenilo)-(7-(3-morfolina-4-il-propoxi)-6-aminoquinazolina-4-ilo)-amina.

Country Status (31)

Country Link
US (1) US20030050313A1 (es)
EP (1) EP1265874B1 (es)
JP (1) JP2003524006A (es)
KR (1) KR20030011773A (es)
CN (1) CN1171877C (es)
AR (1) AR027377A1 (es)
AT (1) ATE296810T1 (es)
AU (1) AU2001228478A1 (es)
BR (1) BR0108695A (es)
CA (1) CA2401171A1 (es)
CO (1) CO5280058A1 (es)
DE (2) DE10009267A1 (es)
EA (1) EA005213B1 (es)
EG (1) EG23221A (es)
ES (1) ES2240483T3 (es)
GT (1) GT200100025A (es)
HK (1) HK1054551B (es)
HU (1) HUP0204510A3 (es)
IL (1) IL151206A0 (es)
MX (1) MXPA02008301A (es)
MY (1) MY133846A (es)
PA (1) PA8512701A1 (es)
PE (1) PE20011073A1 (es)
PL (1) PL357774A1 (es)
PT (1) PT1265874E (es)
SV (1) SV2002000320A (es)
TN (1) TNSN01031A1 (es)
UY (1) UY26594A1 (es)
WO (1) WO2001062743A2 (es)
YU (1) YU62502A (es)
ZA (1) ZA200206107B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20040945A1 (es) * 2003-02-05 2004-12-14 Warner Lambert Co Preparacion de quinazolinas substituidas
WO2006081741A1 (en) * 2005-02-05 2006-08-10 Piaoyang Sun Quinazoline compounds or their medical salts and preparation and medical usage thereof
JP5250901B2 (ja) * 2007-02-23 2013-07-31 学校法人慶應義塾 アニリノキナゾリン系化合物及びその用途
US7829574B2 (en) * 2008-05-09 2010-11-09 Hutchison Medipharma Enterprises Limited Substituted quinazoline compounds and their use in treating angiogenesis-related diseases
CN105399688A (zh) * 2015-12-02 2016-03-16 西南科技大学 一种吉非替尼的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69710712T3 (de) * 1996-04-12 2010-12-23 Warner-Lambert Co. Llc Umkehrbare inhibitoren von tyrosin kinasen

Also Published As

Publication number Publication date
CO5280058A1 (es) 2003-05-30
PT1265874E (pt) 2005-08-31
CN1406232A (zh) 2003-03-26
WO2001062743A2 (de) 2001-08-30
CA2401171A1 (en) 2001-08-30
TNSN01031A1 (en) 2005-11-10
SV2002000320A (es) 2002-06-07
US20030050313A1 (en) 2003-03-13
DE10009267A1 (de) 2001-08-30
HK1054551A1 (en) 2003-12-05
EP1265874A2 (de) 2002-12-18
PE20011073A1 (es) 2001-12-16
AU2001228478A1 (en) 2001-09-03
ZA200206107B (en) 2003-07-31
HUP0204510A2 (en) 2003-05-28
KR20030011773A (ko) 2003-02-11
DE50106391D1 (de) 2005-07-07
HK1054551B (zh) 2005-06-03
EA005213B1 (ru) 2004-12-30
PL357774A1 (en) 2004-07-26
PA8512701A1 (es) 2002-02-21
EA200200885A1 (ru) 2003-02-27
ES2240483T3 (es) 2005-10-16
YU62502A (sh) 2005-03-15
CN1171877C (zh) 2004-10-20
HUP0204510A3 (en) 2003-07-28
EG23221A (en) 2004-08-31
ATE296810T1 (de) 2005-06-15
MY133846A (en) 2007-11-30
IL151206A0 (en) 2003-04-10
AR027377A1 (es) 2003-03-26
BR0108695A (pt) 2002-12-10
MXPA02008301A (es) 2004-05-14
WO2001062743A3 (de) 2002-03-14
EP1265874B1 (de) 2005-06-01
JP2003524006A (ja) 2003-08-12
GT200100025A (es) 2003-09-22

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20130215