UY23795A1 - Procedimiento de preparación de liposomas que contienen fe (ii) biodisponible - Google Patents
Procedimiento de preparación de liposomas que contienen fe (ii) biodisponibleInfo
- Publication number
- UY23795A1 UY23795A1 UY23795A UY23795A UY23795A1 UY 23795 A1 UY23795 A1 UY 23795A1 UY 23795 A UY23795 A UY 23795A UY 23795 A UY23795 A UY 23795A UY 23795 A1 UY23795 A1 UY 23795A1
- Authority
- UY
- Uruguay
- Prior art keywords
- iron
- liposomes
- thawing
- procedure
- suspension
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING OR TREATMENT THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
- A23C9/1522—Inorganic additives, e.g. minerals, trace elements; Chlorination or fluoridation of milk; Organic salts or complexes of metals other than natrium or kalium; Calcium enrichment of milk
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dairy Products (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
Se propone un aditivo para suplementar la ingesta de hierro, que comprende hierro (II) biodisponible en medio acuoso, encapsulado en liposomas. Dicho medio comprende agentes reductores, tal como ácido ascórbico o sus sales como estabilizante del estado reducido del hierro. Se propone un procedimiento de preparación de los liposomas portadores del hierro biodisponible a partir de sales de hierro (II) y fosfoglicéridos, en medio acuoso. Procedimiento para preparar liposomas, caracterizado por que comprende formar una suspensión homogénea en agua de fosfoglicéridos y descongelar a temperatura ambiente la suspensión formada, en ciclos y repetidos al menos dos veces, de congelamiento rápido y descolgelamiento lento, incorporar a la suspensión homogeneizada y descongelada, hierro (ll) en solución acuosa que incluye agentes reductores, capaces de inhibir la oxidación a hierro (ll) repetir de congelamiento y descongelamiento lento y separar los liposomas formados.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AR32654193 | 1993-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY23795A1 true UY23795A1 (es) | 1995-12-22 |
Family
ID=3478880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY23795A UY23795A1 (es) | 1993-11-09 | 1994-06-24 | Procedimiento de preparación de liposomas que contienen fe (ii) biodisponible |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5534268A (es) |
| JP (1) | JP3059341B2 (es) |
| KR (1) | KR0163216B1 (es) |
| AU (1) | AU676384B2 (es) |
| BR (1) | BR9402539A (es) |
| CA (1) | CA2126648C (es) |
| CO (1) | CO4230051A1 (es) |
| DE (1) | DE4421686C2 (es) |
| ES (1) | ES2083921B1 (es) |
| FR (1) | FR2712190B1 (es) |
| IT (1) | IT1269946B (es) |
| MY (1) | MY111380A (es) |
| NZ (1) | NZ264653A (es) |
| PE (1) | PE56594A1 (es) |
| UY (1) | UY23795A1 (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2735658B1 (fr) * | 1995-06-21 | 1997-09-12 | Capsulis | Encapsulation de composes a usage alimentaire par des tensioactifs |
| US5707670A (en) * | 1996-08-29 | 1998-01-13 | The Procter & Gamble Company | Use of bilayer forming emulsifiers in nutritional compositions comprising divalent mineral salts to minimize off-tastes and interactions with other dietary components |
| CA2402520A1 (en) * | 2000-03-13 | 2001-09-20 | Kenneth Beckman | Biocidal methods and compositions |
| EP1427393A2 (de) * | 2000-05-02 | 2004-06-16 | Pharmacept GmbH | Wirkstoffhaltige liposome |
| EP1432403B1 (en) * | 2001-10-03 | 2010-07-28 | Celator Pharmaceuticals, Inc. | Liposome loading with metal ions |
| DK1499294T3 (da) * | 2002-04-29 | 2010-12-06 | Biotesys Gmbh | Polymeriserede, peptid-modificerede lipider som biologiske transportsystemer til mikronæringsstoffer |
| AU2003257313A1 (en) * | 2002-08-13 | 2004-02-25 | Vitalstate Canada Ltd. | Multi-phase delivery system comprising a semi-solid matrix phase |
| KR20040048749A (ko) * | 2002-12-04 | 2004-06-10 | 곽해수 | 비타민 ｃ가 함유된 미세캡슐 및 이를 포함하는철분강화우유 |
| CA2521620C (en) | 2003-04-11 | 2012-11-27 | Cargill, Incorporated | Pellet systems for preparing beverages |
| JP4950890B2 (ja) * | 2004-09-13 | 2012-06-13 | ギリアード サイエンシーズ， インコーポレイテッド | 動物に対する鉄の送達 |
| US9445975B2 (en) | 2008-10-03 | 2016-09-20 | Access Business Group International, Llc | Composition and method for preparing stable unilamellar liposomal suspension |
| JP2010115151A (ja) * | 2008-11-13 | 2010-05-27 | Morinaga Milk Ind Co Ltd | 調製粉乳の製造方法 |
| JP4927806B2 (ja) * | 2008-11-13 | 2012-05-09 | 森永乳業株式会社 | 調製粉乳の製造方法 |
| IT1398765B1 (it) * | 2010-03-02 | 2013-03-18 | A V D Reform S R L | Integratore alimentare a base di ferro e procedimento per ottenere detto integratore |
| RU2453149C1 (ru) * | 2010-10-19 | 2012-06-20 | Государственное научное учреждение Всероссийский научно-исследовательский институт пищевых ароматизаторов, кислот и красителей Российской академии сельскохозяйственных наук (ГНУ ВНИИПАКК Россельхозакадемии) | Способ получения пищевой добавки - лактата железа |
| CN104041584A (zh) * | 2014-05-26 | 2014-09-17 | 张宏宇 | 一种卵磷脂酸奶 |
| IT201700099627A1 (it) * | 2017-09-06 | 2019-03-06 | Anna Angela Barba | Produzione di vettori nano-liposomiali incapsulanti ferro altamente biodisponibile con tecnica in continuo. |
| IT201900019775A1 (it) * | 2019-10-25 | 2021-04-25 | Health Progress Italia S R L | Composizione nutraceutica liposomiale |
| WO2022034609A1 (en) * | 2020-08-11 | 2022-02-17 | Pravin Nalawade | Encapsulated carbonyl iron salt compositions and process thereof |
| CN112516163A (zh) * | 2020-12-21 | 2021-03-19 | 西安医学院 | 一种难溶性三价铁纳米脂质体复合物及其制备方法 |
| IT202200020262A1 (it) | 2022-10-03 | 2024-04-03 | Bio Therapic Italia | Composizione liposomiale comprendente ferro solfato e suo uso |
| IT202300007608A1 (it) | 2023-04-19 | 2024-10-19 | Bio Therapic Italia | Composizione liposomiale comprendente ferro solfato per l’uso nella cura e prevenzione dell’anemia in donne in gravidanza e durante il puerperio |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2481414A (en) * | 1945-04-30 | 1949-09-06 | Wisconsin Alumni Res Found | Stable fortified milk products and process of preparing same |
| US4394149A (en) * | 1978-02-24 | 1983-07-19 | Szoka Jr Francis C | Plant nutriment compositions and method of their application |
| EP0231261B1 (en) * | 1985-07-05 | 1994-04-06 | The Liposome Company, Inc. | Multilamellar liposomes having improved trapping efficiencies |
| JPS62178521A (ja) * | 1986-01-30 | 1987-08-05 | Terumo Corp | ヘモグロビン含有リポソ−ム |
| US5320906A (en) * | 1986-12-15 | 1994-06-14 | Vestar, Inc. | Delivery vehicles with amphiphile-associated active ingredient |
| US5139803A (en) * | 1989-02-09 | 1992-08-18 | Nabisco, Inc. | Method and liposome composition for the stabilization of oxidizable substances |
-
1994
- 1994-06-23 CA CA002126648A patent/CA2126648C/en not_active Expired - Fee Related
- 1994-06-24 BR BR9402539A patent/BR9402539A/pt not_active Application Discontinuation
- 1994-06-24 IT ITMI941319A patent/IT1269946B/it active IP Right Grant
- 1994-06-24 CO CO94027578A patent/CO4230051A1/es unknown
- 1994-06-24 UY UY23795A patent/UY23795A1/es not_active IP Right Cessation
- 1994-06-24 ES ES09401390A patent/ES2083921B1/es not_active Expired - Fee Related
- 1994-06-24 US US08/264,974 patent/US5534268A/en not_active Expired - Lifetime
- 1994-06-24 FR FR9408039A patent/FR2712190B1/fr not_active Expired - Lifetime
- 1994-06-24 PE PE1994245255A patent/PE56594A1/es not_active Application Discontinuation
- 1994-06-24 DE DE4421686A patent/DE4421686C2/de not_active Expired - Lifetime
- 1994-07-29 JP JP6178712A patent/JP3059341B2/ja not_active Expired - Fee Related
- 1994-10-11 NZ NZ264653A patent/NZ264653A/en not_active IP Right Cessation
- 1994-11-07 AU AU77682/94A patent/AU676384B2/en not_active Ceased
- 1994-11-08 MY MYPI94002968A patent/MY111380A/en unknown
- 1994-11-09 KR KR1019940029373A patent/KR0163216B1/ko not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2083921B1 (es) | 1996-12-01 |
| AU676384B2 (en) | 1997-03-06 |
| KR950013500A (ko) | 1995-06-15 |
| MY111380A (en) | 1999-12-31 |
| JPH07233078A (ja) | 1995-09-05 |
| DE4421686A1 (de) | 1995-05-11 |
| US5534268A (en) | 1996-07-09 |
| CA2126648A1 (en) | 1995-05-10 |
| CA2126648C (en) | 2000-10-10 |
| DE4421686C2 (de) | 1997-09-04 |
| FR2712190A1 (fr) | 1995-05-19 |
| IT1269946B (it) | 1997-04-16 |
| CO4230051A1 (es) | 1995-10-19 |
| ITMI941319A0 (it) | 1994-06-24 |
| ITMI941319A1 (it) | 1995-12-24 |
| FR2712190B1 (fr) | 1997-05-16 |
| ES2083921A1 (es) | 1996-04-16 |
| PE56594A1 (es) | 1995-01-16 |
| JP3059341B2 (ja) | 2000-07-04 |
| NZ264653A (en) | 1996-06-25 |
| BR9402539A (pt) | 1995-07-04 |
| KR0163216B1 (ko) | 1998-12-01 |
| AU7768294A (en) | 1995-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| VENC | Patent expired |
Effective date: 20140930 |