[go: up one dir, main page]

US3123641A - Cation-active surface active trilower- - Google Patents

Cation-active surface active trilower- Download PDF

Info

Publication number
US3123641A
US3123641A US3123641DA US3123641A US 3123641 A US3123641 A US 3123641A US 3123641D A US3123641D A US 3123641DA US 3123641 A US3123641 A US 3123641A
Authority
US
United States
Prior art keywords
carbon atoms
propyleneoxide
alkyl
mols
mol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
Publication date
Application granted granted Critical
Publication of US3123641A publication Critical patent/US3123641A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S516/00—Colloid systems and wetting agents; subcombinations thereof; processes of
    • Y10S516/01—Wetting, emulsifying, dispersing, or stabilizing agents
    • Y10S516/07—Organic amine, amide, or n-base containing

Definitions

  • My inve ition relates to the production of novel cationactive surface active chemical compounds which are useful for bactericidal, germicidal, antiseptic, algaecidal, fungicidal, textile softening, corrosion inhibition, antistatic, emulsifying, foam modifying, ore beneficiation, and various other purposes for which certain heretofore known cationic surface active agents have been employed or suggested for use.
  • the specific cation-active surface active agents of my present invention are of the quaternary ammonium type and they are characterized by particularly advantageous properties, simplicity of production and markedly low cost. Certain of them, for instance, those derived from low molecular weight alkyl secondary amines and cyclic amines, can be represented by the formula (I) R R3 wherein R is an alkyl radical containing from 1 to 3 and more particularly from 1 to 2 carbon atoms, R is an alkyl radical containing from 1 to 3 carbon atoms, or
  • R may be a radical of a cyclic amine containing not more than 6 carbon atoms
  • R is a polyoxyalkylene radical containing at least 18 carbon atoms and derived from an a-epoxide containing at least 3 carbon atoms, especially propyleneoxide.
  • R is derived from propyleneoxide
  • R is derived from u-epoxides containing more than 3 carbon atoms, a lesser number of such oxyalkylene groups can be present, subject to the limitation of R containing at least 18 atoms.
  • R is a lower alkyl or alkenyl radical containing from 1 to 4 carbon atoms
  • A is an anion. It is important, for the achievements of the results to which my invention is directed, that the R radical, where it is alkyl, contain not more than 3 carbon atoms and especially that it contain from 1 to 2 carbon atoms and, hence, that it be methyl or ethyl. Likewise, except where is derived from a cyclic amine as hereafter pointed out, it is important that the R radical does not contain over 3 carbon atoms, and, in any event, the maximum number of carbon atoms in R and R does not exceed a total of more than 6, and more particularly does not exceed a total of 4 or 5.
  • R may contain a minimum of 6 of the aforesaid oxyalkylene, particularly oxypropylene, groups, and may contain 40, 50 or 60 or even 100 or more of said groups, it is especially advantageous that the minimum number of said groups be 8 and the preferred range is 8 to 25 or 30 of said groups.
  • a-epoxide as used herein, is intended to cover those compounds, of the type here involved, Where there are two vicinal carbon 3,123,641 Patented Mar. 3, 1964 atoms "connected to one oxygen atom independently of the position of such group in the molecule.
  • polyoxyalkylene, polyoxypropylene and polyoxyethylene are employed in their usual or conventional manner.
  • R is an alkyl radical containing from 1 to 4 carbon atoms, and, as indicated above, since R contains a minimum of 18 carbon atoms, n is at least 6 in the case of the polyoxyalkylene radical being polyoxypropylene and n is at least 3 in the case of the polyoxyalkylene radical being polyoxyhexylene.
  • n is usually up to 60 or more.
  • the polyoxyalkylene radical is polyoxypropylene, it may be represented by the formula n advantageously being from 6 to 30.
  • At least most of those of the particularly preferred quaternary ammonium compounds of my invention which are derived from lower monoalkyl amines can be represented by the formula where R is an alkyl radical containing from 1 to 3, and especially from 1 to 2, carbon atoms, R is and R is where R, is an alkyl radical containing from 1 to 4 carbon atoms, n and n are numbers the sum of which does not exceed 60, the total number of carbon atoms in R and R being at least 18; R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing not more than 4 carbon atoms; and A is an anion.
  • R is an alkyl radical containing from 1 to 3 carbon atoms; alkylene contains not more than 3 carbon atoms, R O is R -a1kylene N R O-a1kylene A where R is an alkyl radical containing from 1 to 3, and
  • R O is 4 and R -O is where R, is an alkyl radical containing from 1 to 4 carbon atoms, n and n are numbers the sum of which does not exceed 60, the total number of carbon atoms in R and R being at least 18; R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing not more than 4 carbon atoms; and A is an anion.
  • Still others of the quaternary ammonium compounds of my invention can be represented by the formulae (V) R-O-alkylene Ra R1N Rz ⁇ A and (VI) R-O-alkylene R3 R 0-alkyleneN where alkylene contains not more than 3 carbon atoms, R-O is in which R; is an alkyl radical containing from 1 to 4 carbon atoms, n, n and n are numbers the sum of which does not exceed 60, the total number of carbon atoms in R, R and R being at least 18; R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing not more than 4 carbon atoms; and A is an anion.
  • Most of the quaternary ammonium compounds of the present invention fall into the category of or correspond to reaction products of quaternizing esters having a hydrocarbon alkyl or alkenyl radical containing not more than 4 carbon atoms, and an anion, with adducts of (a) aliphatic amines or cyclic amines containing a reactive hydrogen and a total of not more than 6 carbon atoms and in which no single aliphatic radical contains more than 3 carbon atoms, with (b) and a-epoxide containing at least 3 and advantageously from 3 :to 8 carbon atoms, the molal ratio of (a) to ,(b) being 1 of (a) to at least 6 of (b) when said u-epoxide contains 3 carbon atoms and ranging down to at least 2.5 of (b) when said a-epoxide contains 8 carbon atoms.
  • Still others of the quaternary ammonium compounds of my invention can be represented by the formula Rg where R is an alkyl radical containing from 1 to 3 carbon atoms, R is an alkyl radical containing from 1 to 3 carbon atoms or is the same as R R is a polyoxyalkylene radical containing at least 18 carbon atoms and derived from an a-epoxide containing from 3 to 8 carbon atoms, R is a hydroxy-al-kyl radical containing from 2. to 4 carbon atoms, and A is hydroxyl or other anion.
  • Such compounds are readily produced by reacting the adducts, such as those dwcribed hereafter in Examples a to v, with ethyleneoxide in an aqueous medium in accordance with known quaternizing techniques.
  • Typical of such compounds are those corresponding to the formulae where R is a polyoxypropylene or polyoxybutylene radical containing say from 6 to 30 oxypropylene or oxybutylene groups.
  • quaternary ammonium compounds which are particularly useful and which may simply and inexpensively be produced are reaction products of quaternizing ester in the form of alkyl and alkenyl halides, sulfates and sulfonates containing from 1 to 4 carbon atoms exemplified by methyl chloride, allyl chloride, methyl chloracetate, and 1 and 2 carbon atom alkyl sulfates, with adducts of (a) alkyl amines having a reactive hydrogen and containing from 1 to 4 carbon atoms, such as dimethylamine and diethylamine, with (b) propyleneoxide or butyleneoxides, said adducts containing 1 mol of (a) to from 6, and preferably from 8, to 30 mols of (b). Purification steps can, if desired, be employed as, for instance, separating unreacted tertiary amines by distillation, etc.
  • the oxyalkylene groups be derived from an a-epoxide containing at least 3 carbon atoms.
  • Ethyleneoxide for instance, is not operative in the practice of my invention since it produces compounds whose properties are radically dilferent from those obtained in accordance with my invention and which would be useless for the purposes for which the cation-active surface active agents of my invention are adapted and intended.
  • a-epoxides whose use is contemplated by my invention in the production of the cation-active surface active agents is propyleneoxide (CH -CHCH3)
  • the a-epoxides containing 4, 5, 6 or more carbon atoms can be used but, for general reasons of lack of economy or commercial availability, are not preferred.
  • a-epoxides Typical of such latter a-epoxides are butylene oxides such as 1,2- butylene oxide, pentylene epoxides, hexylene epoxides, heptylene epoxides, octylene epoxides, dodecylene epoxides, and C C olefin oxides or epoxides, and, as well, styrene epoxide. It will be seen that most of those of the a-epoxides in which the vicinal carbons are terminal can conveniently be represented by the formula where R is an alkyl radical.
  • R is CH and in the representation of the group of propylene oxide, butylene oxides, pentylene oxide and hexylene oxide R contains from 1 to 4 carbon atoms. In the higher molecular weight alkylene oxides, R may contain as high as 16 carbon atoms.
  • ethyleneoxide as the sole alkylene oxide is inoperative for my purposes, small proportions thereof, not to exceed 25% and better still not to exceed 20% by weight of the propyleneoxide or other a-epoxide employed, can be utilized as hereafter described. Mixtures of two or more of the a-epoxides containing at least 3 carbons can, of course, be used as such, as Well as in conjunction with ethyleneoxide, subject to the limitation that the ethyleneoxide must not exceed the aforesaid 20% to 25 of the weight of said u-epoxides.
  • the cation-active surface active agents of my invention are advantageously prepared by initially condensing a lower molecular weight amine, for instance, one containing at least one alkyl radical having from 1 to 3 carbon atoms and no radical containing more than 3 carbon atoms linked to the nitrogen atom of the amine, or by initially condensing a cyclic amine such as piperidine containing not more than 6 carbon atoms, with propyleneoxide or other wepoxide containing at least 3 carbon atoms, advantageously in the presence of a conventional oxyalkylation catalyst such as sodium hydroxide or potassium hydroxide, whereby to produce an intermediate or adduct containing at least 6 oxypropylene groups.
  • a lower molecular weight amine for instance, one containing at least one alkyl radical having from 1 to 3 carbon atoms and no radical containing more than 3 carbon atoms linked to the nitrogen atom of the amine, or by initially condensing a cyclic amine such as piperidine
  • the amines used in the reaction to produce said adducts must contain a reactive hydrogen, which may be hydrogen directly attached to the nitrogen of the amine or which may be in the form of hydroxyl hydrogen, secondary alkyl amines being especially desirable, particularly dimethylamine, diethylamine and methylethylamine.
  • the resulting adduct is then reacted with a quaternizing ester in the form of lower alkyl or alkenyl halides or lower alkyl esters of sulfuric acid or lower alkyl esters of sulfonic acids, or lower alkyl and alkenyl haloacetates, to convert said adduct into the cation-active surface active agents of my present invention.
  • Illustrative examples of such lower molecular weight alkyl halides, haloacetates, sulfates, etc. are methyl chloride, ethyl chloride, methyl bromide, ethyl bromide, methyl iodide, allyl chloride, allyl bromide, methyl chloracetate, ethyl chloracetate, vinyl chloracetate, dimethyl sulfate, and diethyl sulfate.
  • cation-active surface active agents having the required properties in accordance with my in-' tain not more than 4 carbon atoms and, better still, should contain only 1 to 2 carbon atoms.
  • the speed of quaternization in any given instance will be governed by the reactants and the reaction conditions including the temperature and solvent medium utilized.
  • the amines which are utilized in the production of the intermediate adducts or condensation products with the propylene oxide or other a-epoxides are particularly advantageously of aliphatic or acyclic character, although they also include cyclic secondary amines. In all cases, they contain at least one reactive hydrogen directly attached to nitrogen or in a hydroxy group.
  • alkyl amines e.g., methylamine, dimethylamine, ethylamine, diethylamine, methylethylamine, propyl amine, dipropylamine; alkyl hydroxy amines, e.g., monomethylethylthanolarnine, monoethylethanolamine, monomethyldiethanolarnine, dimethylethanolamine, diethylethanolamine and diallylethanolamine; polyamines such as ethylenediarnine, diethylenetriamine and triethylenetetraamine and higher polyamines in which there is at least one short chain alkyl group, as for instance, monomethyl ethylenediamine, dimethyl ethylenediamine and trimethyl ethylenediamine; N,N-dimethyl- N,N diisopropanol propylenediamine 1,3; furfurylamine; cyclic secondary amines containing not more than 6 carbon atoms, typical examples of which are morph
  • Such amines may contain nonreactive substituents such as nitro groups, ether and thioether groups, CN groups, and the like, but, in general, best results will be obtained with the unsubstituted amines.
  • Compatible mixtures of any two or more of said amines, in various proportions, can, of course, be utilized in the production of the intermediate condensation products.
  • the radical A can be any negative or salt-forming radical as, for instance, halogen such as chlorine, bromine and iodine; hydroxy; sulfate, alkyl-sulfuric acid such as methyl sulfuric acid or ethyl sulfuric acid (methosulfate or ethosulfate); nitrate; phosphate; acetate; formate; carbonate; lower alkyl (1 to 4 carbon atoms) sulfonic acids; and the like.
  • halogen such as chlorine, bromine and iodine
  • hydroxy sulfate, alkyl-sulfuric acid such as methyl sulfuric acid or ethyl sulfuric acid (methosulfate or ethosulfate)
  • nitrate phosphate; acetate; formate; carbonate; lower alkyl (1 to 4 carbon atoms) sulfonic acids; and the like.
  • anion is chlorine, bromine, methyl chloroacetate, methosulfate,
  • anionic radicals can be introduced directly into the molecules; and, in the case of others, they can be made, for instance, by substitution for halogen in the cation-active surface active agents of my present invention by known techniques as, for instance, by metathesis procedures.
  • Example 1 46 grams (1 mol) of dimethylamine were placed in an autoclave from which the air was displaced by nitrogen. 58 grams (1 mol) of propyleneoxide were pumped into the dimethylamine in said autoclave and reacted while maintaining the temperature below 25 degrees C. The resulting compound was heated to about 150 degrees C. and 25 mols of propyleneoxide were added to the autoclave over a period of 6 hours while maintaining a nitrogen pressure in the autoclave, said reaction being advantageously carried out in the presence of 2 to 3 grams of potassium hydroxide as a catalyst. The rate of addition of the propyleneoxide was controlled so that the pressure in the autoclave did not exceed 2 atmospheres and the temperature controlled so as not to exceed 200 degrees C. and preferably at about 150 degrees C. Upon completion of the reaction, the reaction mixture was cooled to below 100 degrees C. and flushed out with gaseous nitrogen.
  • R is a polyoxypropylene radical containing about 25 oxypropylene groups.
  • Example 2 (a) To 150 grams of the intermediate condensation product or adduct of part (a) of Example 1 there were added 13.5 grams of ethyl chloroacetate and 15 grams of methanol. The resulting mixture was heated at reflux temperature for 7 hours during which period the reflux temperature rose to about 100 degrees C. and the viscosity increased appreciably. A yield of about 94% of the following compound was obtained:
  • R is a polyoxypropylene radical containing about 25 oxypropylene groups.
  • Example 3 (a) 93 grams (1 mol) of dimethylethanolamine were reacted with 1480 grams (20 mols) of propyleneoxide in the manner described in the latter part (a) of Example 1.
  • R is a polyoxypropylene radical containing approxi mately 20 oxypropylene groups.
  • Example 4 50 grams of the adduct of part (a) of Example 1 were reacted with 3 grams of methyl chloride in the manner described in part (b) of Example 1 to produce a product having the following formula:
  • R is a polyoxypropylene radical containing about 25 oxypropylene groups.
  • Example 5 The process was carried out as described in Example 1 except that, in part (a) thereof, in place of the final 25 mols of propyleneoxide, there was used a mixture of 22 mols of propyleneoxide and 2 mols of ethyleneoxide.
  • R and R are each ethyl; R is wherein n is a number from 6 to 30; R is an alkyl radical containing from 1 to 4 carbon atoms; and A is chlorine.
  • a quaternary ammonium compound having the formula wherein R is an alkyl radical containing from 1 to 3 carbon atoms, R is an alkyl radical containing from 1 to 3 carbon atoms, and compounds wherein R and R are joined together to form with the N atom a member of the group consisting of piperidine, methyl piperidine and pyrrolidine; R is a polyoxypropylene-polyoxyethylene radical in which the number of oxypropylene groups is from 6 to and in which the ethylene oxide constitutes not more than 20% by weight of said radical; R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing from 1 to 4 carbon atoms; and A is an anion.
  • a quaternary ammonium compound having the formula where R is an alkyl radical containing from 1 to 3 carbon atoms, R is an alkyl radical containing from 1 to 3 carbon atoms, and compounds wherein R and R are,
  • R is a polyoxyalkylene radical containing at least 18 carbon atoms and derived from an a-epoxide containing from 3 to 6 carbon atoms, said u-epoxide consisting of carbon, hydrogen and oxygen, and the total number of oxyalkylene groups in said polyoxyalkylene radical not exceeding 60
  • R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing from 1 to 4 carbon atoms
  • A is an anion.
  • a quaternary ammonium compound in accordance with claim 8 wherein up to 25% by weight of R is replaced by a polyoxyethylene radical.

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Description

United States Patent CATION-ACTIVE SURFACE ACTIVE TRILOWER- ALKYLPOLYPROPYLENEOXY QUATERNARY AMIVIONIUM COMPOUNDS Kermit Longley, Park Forest, 111., assign'or to Witco Chemical Company, Inc., New York, N.Y., a corporafion of Delaware No Drawing. Filed Apr. 14, 1960, Ser. No. 22,115
9 Claims. (Cl. 260567.6)
My inve ition relates to the production of novel cationactive surface active chemical compounds which are useful for bactericidal, germicidal, antiseptic, algaecidal, fungicidal, textile softening, corrosion inhibition, antistatic, emulsifying, foam modifying, ore beneficiation, and various other purposes for which certain heretofore known cationic surface active agents have been employed or suggested for use.
The specific cation-active surface active agents of my present invention are of the quaternary ammonium type and they are characterized by particularly advantageous properties, simplicity of production and markedly low cost. Certain of them, for instance, those derived from low molecular weight alkyl secondary amines and cyclic amines, can be represented by the formula (I) R R3 wherein R is an alkyl radical containing from 1 to 3 and more particularly from 1 to 2 carbon atoms, R is an alkyl radical containing from 1 to 3 carbon atoms, or
may be a radical of a cyclic amine containing not more than 6 carbon atoms, R is a polyoxyalkylene radical containing at least 18 carbon atoms and derived from an a-epoxide containing at least 3 carbon atoms, especially propyleneoxide. In those cases where R is derived from propyleneoxide, there will be at least 6 of such propyleneoxide groups in R and, more particularly, it is desired that R contain from 8 to 30 oxypropylene groups. Where R is derived from u-epoxides containing more than 3 carbon atoms, a lesser number of such oxyalkylene groups can be present, subject to the limitation of R containing at least 18 atoms. R is a lower alkyl or alkenyl radical containing from 1 to 4 carbon atoms, and A is an anion. It is important, for the achievements of the results to which my invention is directed, that the R radical, where it is alkyl, contain not more than 3 carbon atoms and especially that it contain from 1 to 2 carbon atoms and, hence, that it be methyl or ethyl. Likewise, except where is derived from a cyclic amine as hereafter pointed out, it is important that the R radical does not contain over 3 carbon atoms, and, in any event, the maximum number of carbon atoms in R and R does not exceed a total of more than 6, and more particularly does not exceed a total of 4 or 5. While R may contain a minimum of 6 of the aforesaid oxyalkylene, particularly oxypropylene, groups, and may contain 40, 50 or 60 or even 100 or more of said groups, it is especially advantageous that the minimum number of said groups be 8 and the preferred range is 8 to 25 or 30 of said groups. The term a-epoxide, as used herein, is intended to cover those compounds, of the type here involved, Where there are two vicinal carbon 3,123,641 Patented Mar. 3, 1964 atoms "connected to one oxygen atom independently of the position of such group in the molecule.
The terms polyoxyalkylene, polyoxypropylene and polyoxyethylene, to the extent that they are used herein or in the claims, are employed in their usual or conventional manner. Thus, in the case of the polyoxyalkylene radical derived from a-epoxides containing from 3 to 6 carbon atoms, to wit, R in the above formula, the same may be represented by where R; is an alkyl radical containing from 1 to 4 carbon atoms, and, as indicated above, since R contains a minimum of 18 carbon atoms, n is at least 6 in the case of the polyoxyalkylene radical being polyoxypropylene and n is at least 3 in the case of the polyoxyalkylene radical being polyoxyhexylene. As indicated above, n is usually up to 60 or more. Where the polyoxyalkylene radical is polyoxypropylene, it may be represented by the formula n advantageously being from 6 to 30.
The foregoing illustrate the polyoxyalkylene and polyoxypropylene radicals where the vicinal carbons are terminal. In the broader, but less preferred, embodiments of my invention, however, the vicinal carbons need not be terminal. A typical illustration of the latter is a polyoxyalkylene radical derived from 2,3-butylene oxide.
At least most of those of the particularly preferred quaternary ammonium compounds of my invention which are derived from lower monoalkyl amines can be represented by the formula where R is an alkyl radical containing from 1 to 3, and especially from 1 to 2, carbon atoms, R is and R is where R, is an alkyl radical containing from 1 to 4 carbon atoms, n and n are numbers the sum of which does not exceed 60, the total number of carbon atoms in R and R being at least 18; R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing not more than 4 carbon atoms; and A is an anion.
Various of those particularly preferred quaternary ammonium compounds of my invention which are derived from lower dialkyl monoalkanolamines can be represented by the formula (III) Rs Rr-N R --O-alky1ene A where R is an alkyl radical containing from 1 to 3, and
- especially from 1 to 2, carbon atoms; R, is an alkyl radical containing from 1 to 3 carbon atoms; alkylene contains not more than 3 carbon atoms, R O is R -a1kylene N R O-a1kylene A where R is an alkyl radical containing from 1 to 3, and
especially from 1 to 2, carbon atoms, alkylene contains not more than 3 carbon atoms, R O is 4 and R -O is where R, is an alkyl radical containing from 1 to 4 carbon atoms, n and n are numbers the sum of which does not exceed 60, the total number of carbon atoms in R and R being at least 18; R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing not more than 4 carbon atoms; and A is an anion.
Still others of the quaternary ammonium compounds of my invention can be represented by the formulae (V) R-O-alkylene Ra R1N Rz \A and (VI) R-O-alkylene R3 R 0-alkyleneN where alkylene contains not more than 3 carbon atoms, R-O is in which R; is an alkyl radical containing from 1 to 4 carbon atoms, n, n and n are numbers the sum of which does not exceed 60, the total number of carbon atoms in R, R and R being at least 18; R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing not more than 4 carbon atoms; and A is an anion.
Most of the quaternary ammonium compounds of the present invention fall into the category of or correspond to reaction products of quaternizing esters having a hydrocarbon alkyl or alkenyl radical containing not more than 4 carbon atoms, and an anion, with adducts of (a) aliphatic amines or cyclic amines containing a reactive hydrogen and a total of not more than 6 carbon atoms and in which no single aliphatic radical contains more than 3 carbon atoms, with (b) and a-epoxide containing at least 3 and advantageously from 3 :to 8 carbon atoms, the molal ratio of (a) to ,(b) being 1 of (a) to at least 6 of (b) when said u-epoxide contains 3 carbon atoms and ranging down to at least 2.5 of (b) when said a-epoxide contains 8 carbon atoms.
Still others of the quaternary ammonium compounds of my invention can be represented by the formula Rg where R is an alkyl radical containing from 1 to 3 carbon atoms, R is an alkyl radical containing from 1 to 3 carbon atoms or is the same as R R is a polyoxyalkylene radical containing at least 18 carbon atoms and derived from an a-epoxide containing from 3 to 8 carbon atoms, R is a hydroxy-al-kyl radical containing from 2. to 4 carbon atoms, and A is hydroxyl or other anion. Such compounds are readily produced by reacting the adducts, such as those dwcribed hereafter in Examples a to v, with ethyleneoxide in an aqueous medium in accordance with known quaternizing techniques. Typical of such compounds are those corresponding to the formulae where R is a polyoxypropylene or polyoxybutylene radical containing say from 6 to 30 oxypropylene or oxybutylene groups.
While, as indicated, many of the novel and useful cation-active surface active agents of my invention can be represented by the above formulae, they may, in general, best be described in the form of reaction products of identified ingredients, as hereafter pointed out, since the active constituent or constituents thereof need not be separated out and recovered as such, the reaction products being usable as such for many purposes without the necessity for resorting to concentration, purification or recovery steps. Thus, for example, although this will be pointed out and described in more detail hereafter, quaternary ammonium compounds which are particularly useful and which may simply and inexpensively be produced are reaction products of quaternizing ester in the form of alkyl and alkenyl halides, sulfates and sulfonates containing from 1 to 4 carbon atoms exemplified by methyl chloride, allyl chloride, methyl chloracetate, and 1 and 2 carbon atom alkyl sulfates, with adducts of (a) alkyl amines having a reactive hydrogen and containing from 1 to 4 carbon atoms, such as dimethylamine and diethylamine, with (b) propyleneoxide or butyleneoxides, said adducts containing 1 mol of (a) to from 6, and preferably from 8, to 30 mols of (b). Purification steps can, if desired, be employed as, for instance, separating unreacted tertiary amines by distillation, etc.
It is important to note that it is critical to my present invention that the oxyalkylene groups be derived from an a-epoxide containing at least 3 carbon atoms. Ethyleneoxide, for instance, is not operative in the practice of my invention since it produces compounds whose properties are radically dilferent from those obtained in accordance with my invention and which would be useless for the purposes for which the cation-active surface active agents of my invention are adapted and intended. The most important embodiment of the a-epoxides whose use is contemplated by my invention in the production of the cation-active surface active agents is propyleneoxide (CH -CHCH3) The a-epoxides containing 4, 5, 6 or more carbon atoms can be used but, for general reasons of lack of economy or commercial availability, are not preferred. Typical of such latter a-epoxides are butylene oxides such as 1,2- butylene oxide, pentylene epoxides, hexylene epoxides, heptylene epoxides, octylene epoxides, dodecylene epoxides, and C C olefin oxides or epoxides, and, as well, styrene epoxide. It will be seen that most of those of the a-epoxides in which the vicinal carbons are terminal can conveniently be represented by the formula where R is an alkyl radical. In the case of propylene oxide, R is CH and in the representation of the group of propylene oxide, butylene oxides, pentylene oxide and hexylene oxide R contains from 1 to 4 carbon atoms. In the higher molecular weight alkylene oxides, R may contain as high as 16 carbon atoms.
While, as I have stated above, the use of ethyleneoxide as the sole alkylene oxide is inoperative for my purposes, small proportions thereof, not to exceed 25% and better still not to exceed 20% by weight of the propyleneoxide or other a-epoxide employed, can be utilized as hereafter described. Mixtures of two or more of the a-epoxides containing at least 3 carbons can, of course, be used as such, as Well as in conjunction with ethyleneoxide, subject to the limitation that the ethyleneoxide must not exceed the aforesaid 20% to 25 of the weight of said u-epoxides.
The cation-active surface active agents of my invention are advantageously prepared by initially condensing a lower molecular weight amine, for instance, one containing at least one alkyl radical having from 1 to 3 carbon atoms and no radical containing more than 3 carbon atoms linked to the nitrogen atom of the amine, or by initially condensing a cyclic amine such as piperidine containing not more than 6 carbon atoms, with propyleneoxide or other wepoxide containing at least 3 carbon atoms, advantageously in the presence of a conventional oxyalkylation catalyst such as sodium hydroxide or potassium hydroxide, whereby to produce an intermediate or adduct containing at least 6 oxypropylene groups. The amines used in the reaction to produce said adducts must contain a reactive hydrogen, which may be hydrogen directly attached to the nitrogen of the amine or which may be in the form of hydroxyl hydrogen, secondary alkyl amines being especially desirable, particularly dimethylamine, diethylamine and methylethylamine. The resulting adduct is then reacted with a quaternizing ester in the form of lower alkyl or alkenyl halides or lower alkyl esters of sulfuric acid or lower alkyl esters of sulfonic acids, or lower alkyl and alkenyl haloacetates, to convert said adduct into the cation-active surface active agents of my present invention. Illustrative examples of such lower molecular weight alkyl halides, haloacetates, sulfates, etc. are methyl chloride, ethyl chloride, methyl bromide, ethyl bromide, methyl iodide, allyl chloride, allyl bromide, methyl chloracetate, ethyl chloracetate, vinyl chloracetate, dimethyl sulfate, and diethyl sulfate. In order to obtain cation-active surface active agents having the required properties in accordance with my in-' tain not more than 4 carbon atoms and, better still, should contain only 1 to 2 carbon atoms. The speed of quaternization in any given instance will be governed by the reactants and the reaction conditions including the temperature and solvent medium utilized.
Illustrative examples of the intermediate condensation products or adducts which are subsequently converted into the cation-active surface active agents or quaternary ammonium compounds encompassed by my present invention are the following:
(a) Condensation products of 1 mol of dimethylamine with 6 to 10 mols of propyleneoxide.
(b) Condensation products of 1 mol of dimethylamine with 20 mols of propyleneoxide.
(c) Condensation products of 1 mol of dimethylamine with a mixture of 25 mols of propyleneoxide and 5 mols of ethyleneoxide.
(d) Condensation products of 1 mol of dimethylamine with 1 to 2 mols of ethyleneoxide, reacted with 20 mols of propyleneoxide.
(e) Condensation products of 1 mol of methylamine with 30 to 40 mols of propyleneoxide.
(f) Condensation products of 1 mol of methylethylamine with 10 to 60 mols of propyleneoxide.
(g) Condensation product of 1 mol of diethylamine with 30 mols of propyleneoxide.
(h) Condensation products of 1 mol of dimethylamine with 10 to 20 mols of propyleneoxide and then with 1 mol of ethyleneoxide.
(i) Condensation products of 1 mol of methylpropylamine with 10 to 25 mols of propyleneoxide.
(j) Condensation products of 1 mol of dimethylamine with 10 to 15 mols of butyleneoxide.
(k) Condensation products of 1 mol of diethylamine with 10 to 18 mols of butyleneoxide.
(l) Condensation products of 1 mol of piperidine with 10 to 25 mols of propyleneoxide.
(m) Condensation products of 1 mol of methylpiperidine with 10 to 25 mols of propyleneoxide.
(n) Condensation products of 1 mol of pyrrolidine with 10 to 25 mols of propyleneoxide.
(o) condensation products of /2 mol of methylamine and /2 mol of diethylamine with 6 to 3 mols of propyleneoxide.
(p) Condensation products of /3 mol of dimethylamine and /3 mol of diethylamine with 10 to 25 mols of propyleneoxide.
(q) Condensation products of 1 mol of morpholine with from 6 to 30 mols of propyleneoxide.
(r) Condensation products of 1 mol of diethylethanolamine with 8 to 20 mols of propyleneoxide.
(s) Condensation products of 1 mol of diallylethanolamine with 8 to 25 mols of propyleneoxide.
(t) Condensation products of 1 mol of furfurylamine with 8 to 25 mols of propyleneoxide.
(u) Condensation products of 1 mol of 2-amino-1,3- propanediol with 8 to 25 mols of propyleneoxide.
(v) Condensation products of 1 mol of diethylamine with 6 to 25 mols of propyleneoxide.
The amines which are utilized in the production of the intermediate adducts or condensation products with the propylene oxide or other a-epoxides are particularly advantageously of aliphatic or acyclic character, although they also include cyclic secondary amines. In all cases, they contain at least one reactive hydrogen directly attached to nitrogen or in a hydroxy group. Illustrative examples of such amines are alkyl amines, e.g., methylamine, dimethylamine, ethylamine, diethylamine, methylethylamine, propyl amine, dipropylamine; alkyl hydroxy amines, e.g., monomethylethylthanolarnine, monoethylethanolamine, monomethyldiethanolarnine, dimethylethanolamine, diethylethanolamine and diallylethanolamine; polyamines such as ethylenediarnine, diethylenetriamine and triethylenetetraamine and higher polyamines in which there is at least one short chain alkyl group, as for instance, monomethyl ethylenediamine, dimethyl ethylenediamine and trimethyl ethylenediamine; N,N-dimethyl- N,N diisopropanol propylenediamine 1,3; furfurylamine; cyclic secondary amines containing not more than 6 carbon atoms, typical examples of which are morpholine, piperidine, methylpiperidine, and pyrrolidine. Such amines may contain nonreactive substituents such as nitro groups, ether and thioether groups, CN groups, and the like, but, in general, best results will be obtained with the unsubstituted amines. Compatible mixtures of any two or more of said amines, in various proportions, can, of course, be utilized in the production of the intermediate condensation products.
The radical A can be any negative or salt-forming radical as, for instance, halogen such as chlorine, bromine and iodine; hydroxy; sulfate, alkyl-sulfuric acid such as methyl sulfuric acid or ethyl sulfuric acid (methosulfate or ethosulfate); nitrate; phosphate; acetate; formate; carbonate; lower alkyl (1 to 4 carbon atoms) sulfonic acids; and the like. Of particular importance are those of the cation-active surface active agents of my invention in which the anion is chlorine, bromine, methyl chloroacetate, methosulfate, and ethosulfate. Various of said anionic radicals can be introduced directly into the molecules; and, in the case of others, they can be made, for instance, by substitution for halogen in the cation-active surface active agents of my present invention by known techniques as, for instance, by metathesis procedures.
The following examples are illustrative of the production of typical cation-active surface active agents in accordance with my invention. It will be understood that other reactants can be utilized, proportions modified, temperature and other conditions, and concentration or purification procedures employed, all within the guiding principles taught herein, without departing from the essential v teachings disclosed herein.
Example 1 (a) 46 grams (1 mol) of dimethylamine were placed in an autoclave from which the air was displaced by nitrogen. 58 grams (1 mol) of propyleneoxide were pumped into the dimethylamine in said autoclave and reacted while maintaining the temperature below 25 degrees C. The resulting compound was heated to about 150 degrees C. and 25 mols of propyleneoxide were added to the autoclave over a period of 6 hours while maintaining a nitrogen pressure in the autoclave, said reaction being advantageously carried out in the presence of 2 to 3 grams of potassium hydroxide as a catalyst. The rate of addition of the propyleneoxide was controlled so that the pressure in the autoclave did not exceed 2 atmospheres and the temperature controlled so as not to exceed 200 degrees C. and preferably at about 150 degrees C. Upon completion of the reaction, the reaction mixture was cooled to below 100 degrees C. and flushed out with gaseous nitrogen.
(b) To 77 grams of the intermediate condensation product or adduct of part (a) hereof there were added 8 grams of methanol and 4 grams of ethyl chloride and the resulting mixture was refluxed, with stirring, for 5 hours. During this period, the temperature of reflux rose somewhat and the viscosity of the reaction mixture increased appreciably. A yield in excess of 90% of theoretical of the following product was obtained:
CH3 C2115 CHa-N R/ Cl wherein R is a polyoxypropylene radical containing about 25 oxypropylene groups.
Example 2 (a) To 150 grams of the intermediate condensation product or adduct of part (a) of Example 1 there were added 13.5 grams of ethyl chloroacetate and 15 grams of methanol. The resulting mixture was heated at reflux temperature for 7 hours during which period the reflux temperature rose to about 100 degrees C. and the viscosity increased appreciably. A yield of about 94% of the following compound was obtained:
CH3 CH2COOC1H5 CHa-N R Cl wherein R is a polyoxypropylene radical containing about 25 oxypropylene groups.
(17) To the product of part (a) of this Example 2 there were added 50 ml. of water and 1 ml. of concentrated hydrochloric acid, and heating at reflux was continued to hydrolyze the ester to the free acid. The latter was neutralized with sodium hydroxide to form the sodium salt, the final compound corresponding to the formula CH3 CHzC O 0N8 CH3N R Cl
where R is the same as set forth above.
Example 3 (a) 93 grams (1 mol) of dimethylethanolamine were reacted with 1480 grams (20 mols) of propyleneoxide in the manner described in the latter part (a) of Example 1.
(b) 50 grams of the adduct of part (a) of this Example 3 were reacted with 5 grams of butyl chloride, in methanol, in the manner described in part (b) of Example 1. The final reaction product, in a yield of in excess of comprised the following product:
CH; 04119 CH3 C1 where R is a polyoxypropylene radical containing approxi mately 20 oxypropylene groups.
Example 4 50 grams of the adduct of part (a) of Example 1 were reacted with 3 grams of methyl chloride in the manner described in part (b) of Example 1 to produce a product having the following formula:
where R is a polyoxypropylene radical containing about 25 oxypropylene groups.
Example 5 The process was carried out as described in Example 1 except that, in part (a) thereof, in place of the final 25 mols of propyleneoxide, there was used a mixture of 22 mols of propyleneoxide and 2 mols of ethyleneoxide.
This application is a continuation-in-part of my application Serial No. 524,297, filed July 25, 1955, and now abandoned.
What I claim as new and desire to protect by Letters Patent of the United States is:
l. A quaternary ammonium compound having the formula wherein R is an alkyl radical containing from 1 to 3 carbon atoms, R is a member selected from the group 9 consisting of an alkyl radical containing from 1 to 3 carbon atoms and CHz-CHO H I 11' and components wherein R and R are joined together to form with the N atom a member of the group consisting of piperidine, methyl piperidine and pyrrolidine; R is where R; is an alkyl radical containing from 1 to 4 carbon atoms, n and n are numbers the sum of which does not exceed 60, the total number of carbon atoms in R being at least 18; R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing from 1 to 4 carbon atoms; and A is an anion.
2. A quaternary ammonium compound in accordance with claim 1, wherein R is CH 3. A quaternary ammonium compound having the formula wherein R is an alkyl radical containing from 1 to 3 carbon atoms; R is an alkyl radical containing from 1 to 3 carbon atoms; R is wherein n is a number from 6 to 30; R is an alkyl radical having from 1 to 4 carbon atoms; and A is an anion.
5. A quaternary ammonium compound having the formula R R3 Rr N R: \A.
wherein R and R are each ethyl; R is wherein n is a number from 6 to 30; R is an alkyl radical containing from 1 to 4 carbon atoms; and A is chlorine.
6. A quaternary ammonium compound in accordance with claim 1 wherein up to 20% by weight of R is replaced by a polyoxyethylene radical.
10 7. A quaternary ammonium compound having the formula wherein R is an alkyl radical containing from 1 to 3 carbon atoms, R is an alkyl radical containing from 1 to 3 carbon atoms, and compounds wherein R and R are joined together to form with the N atom a member of the group consisting of piperidine, methyl piperidine and pyrrolidine; R is a polyoxypropylene-polyoxyethylene radical in which the number of oxypropylene groups is from 6 to and in which the ethylene oxide constitutes not more than 20% by weight of said radical; R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing from 1 to 4 carbon atoms; and A is an anion.
8. A quaternary ammonium compound having the formula where R is an alkyl radical containing from 1 to 3 carbon atoms, R is an alkyl radical containing from 1 to 3 carbon atoms, and compounds wherein R and R are,
joined together to form with the N atom a cyclic amine radical containing not more than 6 carbon atoms, with the proviso that the total number of carbon atoms in R and R does not exceed 6; R is a polyoxyalkylene radical containing at least 18 carbon atoms and derived from an a-epoxide containing from 3 to 6 carbon atoms, said u-epoxide consisting of carbon, hydrogen and oxygen, and the total number of oxyalkylene groups in said polyoxyalkylene radical not exceeding 60, R is a hydrocarbon radical selected from the group consisting of alkyl and alkenyl radicals containing from 1 to 4 carbon atoms; and A is an anion.
9. A quaternary ammonium compound in accordance with claim 8, wherein up to 25% by weight of R is replaced by a polyoxyethylene radical.
References Cited in the file of this patent UNITED STATES PATENTS 1,518,689 Callsen Dec. 9, 1924 2,060,850 Calcott et al Nov. 17, 1936 2,087,506 De Groote July 20, 1937 2,137,314 Ulrich Nov. 22, 1938 2,161,322 Steindorif June 6, 1939 2,185,163 Ulrich Dec. 26, 1939 2,214,352 Schoeller et al. Sept. 10, 1940 2,677,700 Jackson et al May 4, 1954 2,701,239 Ryznar Feb. 1, 1955 2,759,975 Chiddix et al Aug. 21, 1956 2,775,604 Zech Dec. 25, 1956 2,897,170 Gruber July 28, 1959 FOREIGN PATENTS 1,092,657 France Apr. 26, 1955 OTHER REFERENCES Ralson et al.: J.A.C.S., volume 69, pages 2095-2097 (1947).
Cuisa: C.A., volume 42, page 4653 (1948).
Schultz: J.A.C.S., volume 70, pages 48-52 (1948).

Claims (1)

1. A QUATERNARY AMMONIUM COMPOUND HAVING THE FORMULA
US3123641D Cation-active surface active trilower- Expired - Lifetime US3123641A (en)

Publications (1)

Publication Number Publication Date
US3123641A true US3123641A (en) 1964-03-03

Family

ID=3453171

Family Applications (1)

Application Number Title Priority Date Filing Date
US3123641D Expired - Lifetime US3123641A (en) Cation-active surface active trilower-

Country Status (1)

Country Link
US (1) US3123641A (en)

Cited By (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3310429A (en) * 1962-08-03 1967-03-21 Boeing Co Method of repelling water from a transparent member
US3328464A (en) * 1963-12-14 1967-06-27 Dehydag Gmbh Phenoxy- and phenylthio-propanol-quaternary ammonium compounds
US3352709A (en) * 1963-01-04 1967-11-14 Boeing Co Method of repelling water from a transparent member
US3647539A (en) * 1970-02-09 1972-03-07 Ampex Magnetic recording tape and method for preparing the same
US3668136A (en) * 1969-07-07 1972-06-06 Witco Chemical Corp Compatible anionic-catonic surfactant compositions
DE2256234A1 (en) * 1971-11-19 1973-05-24 Mo Och Domsjoe Ab CATIONIC SURFACE-ACTIVE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE FOR THE TREATMENT OF TEXTILE MATERIALS
US3876760A (en) * 1969-10-23 1975-04-08 Bristol Myers Co Hair dressing compositions containing a hair substantive quaternary resin
US3959463A (en) * 1972-07-10 1976-05-25 Bristol-Myers Company Hair dressing compositions containing a hair substantive quaternary resin
US3984731A (en) * 1973-10-10 1976-10-05 Mar-Chem, Incorporated Method for neutralizing static electricity
US4169279A (en) * 1978-09-25 1979-09-25 Lester Laboratories, Inc. Method for neutralizing static electricity with mixed atmospheres
US4171279A (en) * 1977-03-14 1979-10-16 The Dow Chemical Company Polyglycolamine corrosion inhibitors
US4313895A (en) * 1980-06-24 1982-02-02 Akzona Incorporated Alkoxylated diquaternary ammonium compounds
US4664848A (en) * 1982-12-23 1987-05-12 The Procter & Gamble Company Detergent compositions containing cationic compounds having clay soil removal/anti-redeposition properties
US5317003A (en) * 1992-07-16 1994-05-31 Monsanto Company Herbicidal compositions comprising glyphosate salts and alkoxylated quaternary amine surfactants
US5402304A (en) * 1993-02-18 1995-03-28 Smith; Dirk S. Static eliminator air enhancement device
US5430005A (en) * 1991-08-02 1995-07-04 Monsanto Company Herbicidal compositions
US5464807A (en) * 1990-02-05 1995-11-07 Monsanto Company Methods of using glyphosate compositions comprising alkoxylated quaternary ammonium surfactants
US5492875A (en) * 1993-07-21 1996-02-20 Hoechst Ag Catalyst for nucleophilic aromatic substitutions
WO1997009375A1 (en) * 1995-09-07 1997-03-13 Southern Clay Products, Inc. Formulations including improved organoclay compositions
US5663111A (en) * 1995-09-07 1997-09-02 Southern Clay Products, Inc. Organoclay compositions
US20060099128A1 (en) * 2002-06-21 2006-05-11 Andrews Alan W Synthetic magnesium silicate compositions and process for the production thereof
US20060147367A1 (en) * 2002-12-20 2006-07-06 Terrance Temperly Process for the produciton of synthetic magnesium silicate compositons
US20060199889A1 (en) * 2005-03-02 2006-09-07 Hunter Douglas L Silanated clay compositions and methods for making and using silanated clay compositions
US20060199890A1 (en) * 2005-03-02 2006-09-07 Southern Clay Products, Inc. Nanocomposites including modified fillers

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1518689A (en) * 1924-02-14 1924-12-09 Farbenfab Vorm Bayer F & Co Choline compound having laxative properties
US2060850A (en) * 1932-11-08 1936-11-17 Du Pont Quaternary ammonium compounds and process for the production thereof
US2087506A (en) * 1936-08-21 1937-07-20 Tretolite Co Quaternary ammonium salts of high molecular weight acids
US2137314A (en) * 1935-05-22 1938-11-22 Ig Farbenindustrie Ag Process of producing quaternary ammonium compounds
US2161322A (en) * 1936-03-28 1939-06-06 Ig Farbenindustrie Ag C-aliphatic isocyclic amines n-substituted by oxyaliphatic radicals
US2185163A (en) * 1935-07-24 1939-12-26 Ig Farbenindustrie Ag Polyoxyalkylene ammonium compounds and process of preparing them
US2214352A (en) * 1935-06-22 1940-09-10 Gen Aniline & Film Corp Process for the production of condensation products containing onium groups
US2677700A (en) * 1951-05-31 1954-05-04 Wyandotte Chemicals Corp Polyoxyalkylene surface active agents
US2701239A (en) * 1952-01-16 1955-02-01 Nat Aluminate Corp Steam generation and compositions for inhibiting foaming
FR1092657A (en) * 1952-12-12 1955-04-26 Ciba Geigy Process for the preparation of quaternary ammonium salts, products obtained by this process and their use
US2759975A (en) * 1952-05-28 1956-08-21 Gen Aniline & Film Corp Mixed alkyl-benzyl-alkylol quaternary ammonium salts
US2775604A (en) * 1953-02-09 1956-12-25 Atlas Powder Co Quaternary ammonium halides
US2897170A (en) * 1954-04-09 1959-07-28 American Cyanamid Co Antistatic treatment with a quaternary ammonium compound containing a polyetheneoxy grouping and products thereof

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1518689A (en) * 1924-02-14 1924-12-09 Farbenfab Vorm Bayer F & Co Choline compound having laxative properties
US2060850A (en) * 1932-11-08 1936-11-17 Du Pont Quaternary ammonium compounds and process for the production thereof
US2137314A (en) * 1935-05-22 1938-11-22 Ig Farbenindustrie Ag Process of producing quaternary ammonium compounds
US2214352A (en) * 1935-06-22 1940-09-10 Gen Aniline & Film Corp Process for the production of condensation products containing onium groups
US2185163A (en) * 1935-07-24 1939-12-26 Ig Farbenindustrie Ag Polyoxyalkylene ammonium compounds and process of preparing them
US2161322A (en) * 1936-03-28 1939-06-06 Ig Farbenindustrie Ag C-aliphatic isocyclic amines n-substituted by oxyaliphatic radicals
US2087506A (en) * 1936-08-21 1937-07-20 Tretolite Co Quaternary ammonium salts of high molecular weight acids
US2677700A (en) * 1951-05-31 1954-05-04 Wyandotte Chemicals Corp Polyoxyalkylene surface active agents
US2701239A (en) * 1952-01-16 1955-02-01 Nat Aluminate Corp Steam generation and compositions for inhibiting foaming
US2759975A (en) * 1952-05-28 1956-08-21 Gen Aniline & Film Corp Mixed alkyl-benzyl-alkylol quaternary ammonium salts
FR1092657A (en) * 1952-12-12 1955-04-26 Ciba Geigy Process for the preparation of quaternary ammonium salts, products obtained by this process and their use
US2775604A (en) * 1953-02-09 1956-12-25 Atlas Powder Co Quaternary ammonium halides
US2897170A (en) * 1954-04-09 1959-07-28 American Cyanamid Co Antistatic treatment with a quaternary ammonium compound containing a polyetheneoxy grouping and products thereof

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3310429A (en) * 1962-08-03 1967-03-21 Boeing Co Method of repelling water from a transparent member
US3352709A (en) * 1963-01-04 1967-11-14 Boeing Co Method of repelling water from a transparent member
US3328464A (en) * 1963-12-14 1967-06-27 Dehydag Gmbh Phenoxy- and phenylthio-propanol-quaternary ammonium compounds
US3668136A (en) * 1969-07-07 1972-06-06 Witco Chemical Corp Compatible anionic-catonic surfactant compositions
US3876760A (en) * 1969-10-23 1975-04-08 Bristol Myers Co Hair dressing compositions containing a hair substantive quaternary resin
US3647539A (en) * 1970-02-09 1972-03-07 Ampex Magnetic recording tape and method for preparing the same
DE2256234A1 (en) * 1971-11-19 1973-05-24 Mo Och Domsjoe Ab CATIONIC SURFACE-ACTIVE COMPOUNDS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE FOR THE TREATMENT OF TEXTILE MATERIALS
US3959463A (en) * 1972-07-10 1976-05-25 Bristol-Myers Company Hair dressing compositions containing a hair substantive quaternary resin
US3984731A (en) * 1973-10-10 1976-10-05 Mar-Chem, Incorporated Method for neutralizing static electricity
US4171279A (en) * 1977-03-14 1979-10-16 The Dow Chemical Company Polyglycolamine corrosion inhibitors
US4169279A (en) * 1978-09-25 1979-09-25 Lester Laboratories, Inc. Method for neutralizing static electricity with mixed atmospheres
US4313895A (en) * 1980-06-24 1982-02-02 Akzona Incorporated Alkoxylated diquaternary ammonium compounds
US4664848A (en) * 1982-12-23 1987-05-12 The Procter & Gamble Company Detergent compositions containing cationic compounds having clay soil removal/anti-redeposition properties
US5652197A (en) * 1990-02-05 1997-07-29 Monsanto Company Glyphosate compositions
US5464807A (en) * 1990-02-05 1995-11-07 Monsanto Company Methods of using glyphosate compositions comprising alkoxylated quaternary ammonium surfactants
US5430005A (en) * 1991-08-02 1995-07-04 Monsanto Company Herbicidal compositions
US5317003A (en) * 1992-07-16 1994-05-31 Monsanto Company Herbicidal compositions comprising glyphosate salts and alkoxylated quaternary amine surfactants
US5402304A (en) * 1993-02-18 1995-03-28 Smith; Dirk S. Static eliminator air enhancement device
US5492875A (en) * 1993-07-21 1996-02-20 Hoechst Ag Catalyst for nucleophilic aromatic substitutions
WO1997009375A1 (en) * 1995-09-07 1997-03-13 Southern Clay Products, Inc. Formulations including improved organoclay compositions
US5663111A (en) * 1995-09-07 1997-09-02 Southern Clay Products, Inc. Organoclay compositions
US5728764A (en) * 1995-09-07 1998-03-17 Southern Clay Products, Inc. Formulations including improved organoclay compositions
US20060099128A1 (en) * 2002-06-21 2006-05-11 Andrews Alan W Synthetic magnesium silicate compositions and process for the production thereof
US20060147367A1 (en) * 2002-12-20 2006-07-06 Terrance Temperly Process for the produciton of synthetic magnesium silicate compositons
US20060199889A1 (en) * 2005-03-02 2006-09-07 Hunter Douglas L Silanated clay compositions and methods for making and using silanated clay compositions
US20060199890A1 (en) * 2005-03-02 2006-09-07 Southern Clay Products, Inc. Nanocomposites including modified fillers

Similar Documents

Publication Publication Date Title
US3123641A (en) Cation-active surface active trilower-
US3123640A (en) Cation-active surface active aryldi-
US3141905A (en) Cation-active surface active quaternary ammonium compounds
US3389160A (en) Dialkylamino hydroxy organosilicon compounds and derivatives thereof
US3721706A (en) Perfluoro-alkyl-alkylene-sulfonamidoalkylene-dialkylamines and their quaternary ammonium salts
US2697118A (en) Totally hydroxypropylated alkylene diamines
US3636114A (en) Novel quaternary ammonium compounds and method for preparation thereof
US3445440A (en) Hydroxyalkyl quaternary ammonium ethers as antistatic agents
US3231619A (en) Basic primary amino polyether compositions
US2548679A (en) Preparation of alkylthiohydroxypropyl quaternary ammonium halides
US4082790A (en) Method of preparing mercaptans
US2087132A (en) Quaternary ammonium compounds
US3954873A (en) Amino alcohols
JPS61191653A (en) Manufacture of tertiary ether amine
EP0182669A1 (en) Quaternary Ammonium compounds
US4480126A (en) Process for the preparation of quaternary ammonium compounds
US4118324A (en) Fabric softeners
US3084187A (en) Substituted aminoalkanesulfonic acids
JPH07502259A (en) Diamine compounds, manufacturing methods, uses and intermediates
US3517045A (en) Hydroxyalkyl quaternary ammonium ethers as antistatic agents
EP0471137A1 (en) Quaternary ammonium compounds
US3803238A (en) Process for the preparation of secondary amines
CA1191868A (en) Quaternized epichlorohydrin adducts of perfluoro substituted ethanols
US3317609A (en) Epoxide addition reaction with amino alcohol
US4093642A (en) Surface active silicones