[go: up one dir, main page]

US20100272836A1 - Composition for increasing milk production containing artemisia capillaris - Google Patents

Composition for increasing milk production containing artemisia capillaris Download PDF

Info

Publication number
US20100272836A1
US20100272836A1 US12/668,571 US66857108A US2010272836A1 US 20100272836 A1 US20100272836 A1 US 20100272836A1 US 66857108 A US66857108 A US 66857108A US 2010272836 A1 US2010272836 A1 US 2010272836A1
Authority
US
United States
Prior art keywords
artemisia capillaris
artemisia
composition
capillaris
milk production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/668,571
Other languages
English (en)
Inventor
Jeong Chan Ra
Byeung Gie Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RNL Bio Co Ltd
Original Assignee
RNL Bio Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RNL Bio Co Ltd filed Critical RNL Bio Co Ltd
Assigned to RNL BIO CO., LTD. reassignment RNL BIO CO., LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KIM, BYEUNG GIE, RA, JEONG CHAN
Publication of US20100272836A1 publication Critical patent/US20100272836A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Definitions

  • the present invention relates to a composition for increasing milk production of livestock, containing Artemisia capillaris as an active ingredient, and more particularly to a composition and a feed additive for increasing milk production of cows, containing Artemisia capillaris as an active ingredient, and to a composition and a feed additive for reducing the number of somatic cells in livestock milk, containing Artemisia capillaris as an active ingredient.
  • Growth hormones which are used in practice to increase milk production of dairy cows are known to have various physiological actions, including the promotion of cell growth, the promotion of protein production, the promotion of lipolysis and the stimulation of milk secretion in mammals.
  • Human growth hormones were developed as products for promoting the growth of children, and animal growth hormones were developed as agents for increasing milk production of dairy cows, increasing the efficiency of pig feed and promoting the growth of cultured fishes.
  • Artemisia has various Korean names such as Kaae, Kucho, Kiae, Nangmihoja, Bingtae, Akeupae, Yayeundoo, Ae, Aebong, Aeho, Chumae, Chobong, Hyangae and Hwangcho.
  • the whole plant of artemisia contains components such as essential oil, tannin, resin, bitter substances, artemisinin, ascorbic acid and carotene, and the leaf thereof contains essential oil, cineole, thujone, borneol, paraffin, adenine, choline, vitamins A, B and D, etc.
  • the root of artemisia contains polysaccharide artemos, essential oil, dehydromatricaric acid, sterol, tetradecatrien, inulin, mucus, etc.
  • Artemisia has a bitter and acrid taste, and also has warm nature and thus has the ability to disperse cold, stabilize the womb, regulate Qi and blood, expel dampness, warm the uterus, promote bile secretion, invigorate blood, stop bleeding, relieve pain, eliminate blood stasis, regulate menstruation, and restore yang.
  • artemisia is used to alleviate and treat abdominal cold-pain, abdominal cramps caused by diarrhea, chronic diarrhea and dysentery, spitting blood, nasal bleeding, vaginal bleeding, menstrual irregularity, abnormal uterine bleeding, vaginal discharge, fetal irritability, and tumor.
  • the present inventors have found that, when Artemisia capillaris powder, Artemisia capillaris extract or fermented Artemisia capillaris is fed to dairy cows, milk production of the cows can be increased, and the number of somatic cells in raw milk being produced can be decreased which will enable the cows to produce good-quality milk, thereby completing the present invention.
  • the present invention provides a composition and a feed additive for increasing milk production of livestock, containing Artemisia capillaris as an active ingredient.
  • the present invention also provides a composition for promoting human breast milk production, containing Artemisia capillaris as an active ingredient.
  • the present invention also provides a composition and a feed additive for reducing somatic cells in livestock milk, containing Artemisia capillaris as an active ingredient
  • the present invention relates to a composition and a feed additive for increasing milk production of livestock, containing Artemisia capillaris as an active ingredient.
  • the Artemisia capillaris is preferably selected from the group consisting of Artemisia capillaris powder, Artemisia capillaris extract and fermented Artemisia capillaris .
  • the Artemisia capillaris powder may be prepared by drying Artemisia capillaries Thunberg at suitable temperature, finely cutting the dried material, and then grinding the cut material to a size of 20-100 mesh
  • the Artemisia capillaris extract may be prepared by extracting the Artemisia capillaris powder with ethanol and drying the extract
  • the fermented Artemisia capillaris may be prepared by mixing the Artemisia capillaris powder with rice bran and the like, adding a fermentation starter and lactic acid bacteria thereto to ferment the Artemisia capillaris powder, drying the fermented material to a water content of 13-15%, thus preparing fermented Artemisia capillaris powder, and then adding a pharmaceutically acceptable carrier thereto.
  • the Artemisia capillaris powder of the present invention may be mixed with a suitable carrier such as alfalfa at a weight ratio of 18-36:82-67 before use, and the Artemisia capillaris extract may be mixed with a suitable carrier such as alfalfa at a weight ratio of 1.6-7.2:9.4-13.8 before use.
  • the fermented Artemisia capillaris of the present invention may be prepared by mixing 18-36 wt % of Artemisia capillaris powder with 82-64 wt % of rice bran mixture (wheat powder, corn flour, zeolite, etc.), adding a fermentation starter (yeast), various lactic acid bacteria and a suitable carrier thereto, fermenting the mixture for 3-7 days and drying the fermented material.
  • rice bran mixture wheat powder, corn flour, zeolite, etc.
  • the Artemisia capillaris extract, the Artemisia capillaris powder and the fermented Artemisia capillaris powder may be added to a conventional compound feed comprising corn, soybean meal, wheat, tallow, molasses, calcium phosphate, limestone, salt, other minerals, and a vitamin premix in a suitable amount.
  • each of the Artemisia capillaris extract, the Artemisia capillaris powder and the fermented Artemisia capillaris powder is preferably added in an amount of 0.005-50 wt % based on the total weight of feed in order to obtain the desired effect of increasing milk production in livestock.
  • the livestock are preferably selected from the group consisting of cattle, dairy cattle, sheep, mountain sheep, goats, pigs, horses, camels and dogs. More preferably, the livestock are dairy cattle or mountain sheep.
  • the present invention relates to a composition for promoting human breast milk production, containing Artemisia capillaris as an active ingredient.
  • composition may be administered in the form of a pharmaceutical formulation or a functional food.
  • the inventive composition containing Artemisia capillaris as an active ingredient can reduce the number of somatic cells in raw milk produced by livestock, thus enabling production of good quality milk.
  • the present invention relates, in another aspect, to a composition and a feed additive for reducing somatic cells in livestock milk, containing Artemisia capillaris as an active ingredient.
  • composition of the present invention may be prepared into a given formulation according to a conventional method.
  • preparation of the formulation it is preferable that Artemisia capillaris or fermented Artemisia capillaris as an active ingredient be mixed or diluted with a carrier, or encapsulated in a capsule-shaped carrier.
  • the carrier may be a solid, semi-solid or liquid substance acting as a vehicle, excipient or medium for the active ingredients.
  • the formulation may be in the form of tablets, pills, powder, sachet, elixir, suspension, emulsion, solution, syrup, aerosol, soft or hard gelatin capsules, sterilize injectable solution and sterilize powder.
  • the formulation may additionally comprise fillers, anti-aggregating agents, lubricants, wetting agents, perfumes, emulsifiers, preservatives and the like.
  • the pharmaceutical composition according to the present invention may be formulated using a method well known in the art, such that it can provide the rapid, sustained or delayed release of the active ingredient after administration.
  • the Artemisia capillaris extract, the Artemisia capillaris powder or the fermented Artemisia capillaris powder as an active ingredient may be administered orally or parenterally to animals, including humans, in an amount of 10-1,000 mg/kg of body weight, preferably 70-100 mg/kg of body weight, in single or multiple daily doses.
  • the composition of the present invention may be mixed with feed in an amount of 1-50 wt % before feeding or may be fed at a dose of 5-100 g/day/animal.
  • Artemisia capillaris was dried in a dryer to a water content of about 10%. Then, the dried plant was finely cut to a size of 1.5-2 cm, and then ground in a grinder in two steps to a particle size of 20-80 mesh. The resulting Artemisia capillaris powder was mixed with alfalfa as a carrier at a weight ratio of 18:82, thus preparing Artemisia capillaris powder.
  • Artemisia capillaris was placed in a dryer and dried to a water content of about 10%. Then, the dried plant was finely cut to a size of 1.5-2 cm, and the cut plant was extracted with ethanol in an extractor. The extract was dried and ground to fine powder, and the Artemisia capillaris was mixed with alfalfa as a carrier at a weight ratio of 1.8:98.2, thus preparing Artemisia capillaris extract powder.
  • the mixture was fermented for 3-7 days and dried, thus preparing fermented Artemisia capillaries.
  • Holstein dairy cows (1 st to 6 th parity) at 45-280 days after delivery were divided into three groups: a group fed with Artemisia capillaris , and two control groups, each of the groups consisting of 10 cows.
  • the fermented Artemisia capillaris (contained in a formulation in an amount of 18 wt %) was administered to each individual at the time of milking in an amount of 10 g per cow.
  • 500 mg of sustained-release recombinant bovine somatotropin (BST, LG Life Sciences Ltd.) was subcutaneously injected into an alternately selected one of the right and left sides of the ischiorectal fossa at two-week intervals.
  • the amount of concentrate feed was adjusted depending on milk yield, the animals were allowed free access to forage, and other raising conditions followed the usual practice of the test farm. At the start and end of the test, each of the groups was measured for milk production and calculated for the rate of an increase in milk production.
  • Holstein dairy cows (1 st to 5 th parity) at 50-280 days after delivery were divided into three groups fed with Artemisia capillaris , and a control group, each of the groups consisting of 10 cows.
  • the Artemisia capillaris powder (contained in a formulation in an amount of 18 wt %), the Artemisia capillaris extract powder (contained in a formulation in an amount of 3.6 wt %) and the fermented Artemisia capillaris (contained in a formulation in an amount of 18 wt %) were fed to the respective groups in an amount of 10 g per cow.
  • the amount of feed to the control group was adjusted depending on the content of a mixed feed, the animals were allowed free access to forage, and other raising conditions followed the usual practice of the test farm. At the start and end of the test, each of the groups was measured for milk production and calculated for the rate of the increase in milk production.
  • the control group showed no significant change in milk production
  • the group fed with the fermented Artemisia capillaris showed a milk production increase of 4.5 kg for 16 weeks, which corresponded to an increase of 13.2% compared to milk production before administration
  • the Artemisia capillaris extract-fed group and the Artemisia capillaris powder-fed group showed milk production increase of 3.3 kg and 3.9 kg, respectively, which corresponded to increases of 9.4% and 11.4% compared to milk production before administration.
  • the amount of feed to the control group was adjusted depending on the content of a mixed feed, the animals were allowed free access to forage, and other raising conditions followed the usual practice of the test farm. At the start, middle and end of the test, each of the groups was measured for somatic cells. Somatic cell count (SCC) was analyzed using a somatic cell counter (Fossomatic 300, Denmark).
  • the non-fed group showed no significant change in milk production, whereas, in the group fed with the fermented Artemisia capillaris , the number of somatic cells was decreased from 470,000 cells/ml of raw milk to 190,000 cells/ml of raw milk for 16 weeks. The number of somatic cells was decreased from 450,000 cells/ml to 240,000 cells/ml for 16 weeks for the group fed with the Artemisia capillaris extract powder and from 480,000 cells/ml to 220,000 cells/ml for 16 weeks for the group fed with the Artemisia capillaris powder.
  • composition according to the present invention can increase milk production of animals, including humans, and, in addition, can reduce the number of somatic cells in milk being produced, thus enabling production of good quality milk.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Sustainable Development (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
US12/668,571 2007-10-24 2008-04-29 Composition for increasing milk production containing artemisia capillaris Abandoned US20100272836A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020070107341A KR100904396B1 (ko) 2007-10-24 2007-10-24 인진쑥을 유효성분으로 함유하는 산유량 증가용 조성물
KR10-2007-0107341 2007-10-24
PCT/KR2008/002432 WO2009054580A1 (en) 2007-10-24 2008-04-29 Composition for increasing milk production containing artemisia capillaris

Publications (1)

Publication Number Publication Date
US20100272836A1 true US20100272836A1 (en) 2010-10-28

Family

ID=40579670

Family Applications (2)

Application Number Title Priority Date Filing Date
US12/668,571 Abandoned US20100272836A1 (en) 2007-10-24 2008-04-29 Composition for increasing milk production containing artemisia capillaris
US13/678,159 Expired - Fee Related US8911802B2 (en) 2007-10-24 2012-11-15 Composition for increasing milk production containing Artemisia capillaris

Family Applications After (1)

Application Number Title Priority Date Filing Date
US13/678,159 Expired - Fee Related US8911802B2 (en) 2007-10-24 2012-11-15 Composition for increasing milk production containing Artemisia capillaris

Country Status (7)

Country Link
US (2) US20100272836A1 (es)
EP (1) EP2200451A4 (es)
JP (1) JP5399395B2 (es)
KR (1) KR100904396B1 (es)
BR (1) BRPI0812668A2 (es)
MX (1) MX2010000392A (es)
WO (1) WO2009054580A1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107594147A (zh) * 2017-09-28 2018-01-19 淮北市渭水源农业有限公司 一种提高奶牛产奶量、提高乳蛋白的饲料添加剂及其制备方法
CN112753852A (zh) * 2021-01-20 2021-05-07 南京众成正源生物技术有限公司 一种提高鱼虾抗病力的饲料添加剂、其制备方法及应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102192167B1 (ko) * 2019-01-28 2020-12-16 신경희 쑥과 닭의장풀을 함유한 사료효율 증진용 기능성 닭 사료첨가제 혼합조성물 및 그 제조방법

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04253917A (ja) * 1991-02-05 1992-09-09 Chiku Oshiro 茵▲ら▼蒿（カワラヨモギ）、枇杷葉の配合外用剤
US20020034489A1 (en) * 1999-06-10 2002-03-21 Benjamin Wiegland Personal care formulations
KR20030068240A (ko) * 2002-02-14 2003-08-21 김도현 기능성 가축사료 및 그 제조방법
CN1473609A (zh) * 2003-05-22 2004-02-11 李永胜 一种用于防治肝胆疾病的舒肝利胆口服液绿茶蜜奶
WO2006006768A1 (en) * 2004-07-14 2006-01-19 Rnl Life Science Ltd. Composition for promoting growth of animal comprising extracts of artemisia capillaris thunberg, acanthopanax and garlic and feed composition for promoting growth comprising the composition
KR100678519B1 (ko) * 2005-09-02 2007-04-16 김애경 다슬기, 유황오리, 유근피, 송화가루, 산청목, 죽염,인진쑥, 도라지 및 흑두로 구성되는 복합제 추출물을포함하는 지방간 예방 및 치료를 위한 조성물

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5718622A (en) * 1980-07-09 1982-01-30 Kitasato Inst:The Use of interferon inducer
JP3007665B2 (ja) * 1990-09-18 2000-02-07 日清製粉株式会社 コロナウィルス感染症の予防および治療剤ならびに消毒薬
JPH0741427A (ja) * 1993-07-30 1995-02-10 Eisai Co Ltd 抗生剤吸収改善剤及び飼料
JPH06327412A (ja) * 1993-05-25 1994-11-29 Eisai Co Ltd 発育促進又は改善飼料及び方法
JP2590040B2 (ja) * 1993-04-07 1997-03-12 農研テクノ株式会社 飼料改善材とその製造方法
KR100430403B1 (ko) * 2001-12-07 2004-05-03 거창군 쑥이 첨가된 가축사료 및 그 사료로 사육한 한우고기
JP4322498B2 (ja) * 2002-12-09 2009-09-02 コ―キン化学株式会社 牛乳中の体細胞を低減させる方法
JP2005350432A (ja) * 2004-06-14 2005-12-22 National Institute Of Advanced Industrial & Technology プロスタサイクリン生成促進剤
JPWO2006033351A1 (ja) * 2004-09-22 2008-05-15 レドックス・バイオサイエンス株式会社 チオレドキシン発現誘導用組成物
WO2007100567A2 (en) * 2006-02-22 2007-09-07 Greger Douglas L Method and composition for improved meat quality
KR100801549B1 (ko) 2006-12-21 2008-02-11 대한민국 약용식물을 이용한 가축사료용 조성물 및 가축용 사료와음수

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04253917A (ja) * 1991-02-05 1992-09-09 Chiku Oshiro 茵▲ら▼蒿（カワラヨモギ）、枇杷葉の配合外用剤
US20020034489A1 (en) * 1999-06-10 2002-03-21 Benjamin Wiegland Personal care formulations
KR20030068240A (ko) * 2002-02-14 2003-08-21 김도현 기능성 가축사료 및 그 제조방법
CN1473609A (zh) * 2003-05-22 2004-02-11 李永胜 一种用于防治肝胆疾病的舒肝利胆口服液绿茶蜜奶
WO2006006768A1 (en) * 2004-07-14 2006-01-19 Rnl Life Science Ltd. Composition for promoting growth of animal comprising extracts of artemisia capillaris thunberg, acanthopanax and garlic and feed composition for promoting growth comprising the composition
KR100678519B1 (ko) * 2005-09-02 2007-04-16 김애경 다슬기, 유황오리, 유근피, 송화가루, 산청목, 죽염,인진쑥, 도라지 및 흑두로 구성되는 복합제 추출물을포함하는 지방간 예방 및 치료를 위한 조성물

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107594147A (zh) * 2017-09-28 2018-01-19 淮北市渭水源农业有限公司 一种提高奶牛产奶量、提高乳蛋白的饲料添加剂及其制备方法
CN112753852A (zh) * 2021-01-20 2021-05-07 南京众成正源生物技术有限公司 一种提高鱼虾抗病力的饲料添加剂、其制备方法及应用

Also Published As

Publication number Publication date
KR100904396B1 (ko) 2009-06-26
KR20090041694A (ko) 2009-04-29
WO2009054580A1 (en) 2009-04-30
US8911802B2 (en) 2014-12-16
EP2200451A4 (en) 2010-11-03
EP2200451A1 (en) 2010-06-30
JP5399395B2 (ja) 2014-01-29
US20130071377A1 (en) 2013-03-21
MX2010000392A (es) 2010-05-13
BRPI0812668A2 (pt) 2016-07-19
JP2010537664A (ja) 2010-12-09

Similar Documents

Publication Publication Date Title
CN102232487B (zh) 母性动物用生理调节剂及其制备方法
CN102613403B (zh) 一种奶牛围产后期精补料及其制备方法
CN108079284B (zh) 一种提高母猪生产性能的药物、其制备方法及应用
CN105053637A (zh) 一种含有猪肠粘膜蛋白的仔猪配合饲料及其制备方法
CN102870955A (zh) 一种畜禽用秸秆多酶菌剂及制备工艺
CN105192433A (zh) 一种围产期母猪专用全价配合饲料
CN109221675A (zh) 一种断奶仔猪饲料添加剂及其制备方法
CN103053859B (zh) 一种种公猪用中草药复合预混料
CN106387435A (zh) 一种饲料添加剂及其应用和饲料
CN106798123A (zh) 一种缩短母猪产程及改善产后恢复的饲料添加剂
US8911802B2 (en) Composition for increasing milk production containing Artemisia capillaris
CN103316206B (zh) 用于提高母猪泌乳量和仔猪生长性能的中药组合物
CN114599231B (zh) 反刍动物的胰岛素抵抗性抑制剂
CN116392509A (zh) 一种诱导牛体形成牛黄的方法
LU600896B1 (en) A fermented chinese herbal preparation for increasing milk production in sows and its preparation method
CN115517321A (zh) 一种天然饲料原料改善家禽腺胃炎和肌胃炎的制备方法
CN105146116A (zh) 母猪饲料的二次熟化生产方法
RU2815958C1 (ru) Способ повышения воспроизводительной функции кроликов
RU2832580C1 (ru) Фитоминеральная кормовая добавка для поросят
CN116942736B (zh) 一种反刍动物健胃和促生长的复方制剂及其制备方法与应用
RU2764195C1 (ru) Адаптогенная фитосинбиотическая кормовая добавка для телят
CN113244220A (zh) 穿琥宁在制备治疗奶牛乳房炎的兽用药物中的应用及穿琥宁兽用药剂
CN118236422A (zh) 一种用于奶牛怀孕泌乳期预防隐性乳房炎的功能性饲用天然植物组合物及其制备方法
CN119280342A (zh) 一种用于提高僵牛生产性能的复方制剂及其制备方法
CN119563784A (zh) 一种复合猪饲料添加剂及制备方法

Legal Events

Date Code Title Description
AS Assignment

Owner name: RNL BIO CO., LTD., KOREA, REPUBLIC OF

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:RA, JEONG CHAN;KIM, BYEUNG GIE;REEL/FRAME:024541/0187

Effective date: 20100604

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION