[go: up one dir, main page]

US20030109835A1 - Medicament cartridge - Google Patents

Medicament cartridge Download PDF

Info

Publication number
US20030109835A1
US20030109835A1 US10/307,302 US30730202A US2003109835A1 US 20030109835 A1 US20030109835 A1 US 20030109835A1 US 30730202 A US30730202 A US 30730202A US 2003109835 A1 US2003109835 A1 US 2003109835A1
Authority
US
United States
Prior art keywords
medicament
cartridge
delivery apparatus
combination
raised ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/307,302
Other languages
English (en)
Inventor
Robert Woolston
Christopher Langley
Lee Adams
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DCA Design International Ltd
Original Assignee
DCA Design International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DCA Design International Ltd filed Critical DCA Design International Ltd
Assigned to DCA DESIGN INTERNATIONAL LIMITED reassignment DCA DESIGN INTERNATIONAL LIMITED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ADAMS, LEE SIMON, LANGLEY, CHRISTOPHER NIGEL, WOOLSTON, ROBERT
Publication of US20030109835A1 publication Critical patent/US20030109835A1/en
Priority to US11/151,209 priority Critical patent/US7104973B2/en
Abandoned legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06—Ampoules or carpules
    • A61J1/062—Carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A61M2205/584—Means for facilitating use, e.g. by people with impaired vision by visual feedback having a color code
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6045—General characteristics of the apparatus with identification means having complementary physical shapes for indexing or registration purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6063—Optical identification systems
    • A61M2205/6081—Colour codes

Definitions

  • the present invention relates to a medicament cartridge, having particular, but not exclusive application for use with a medication delivery apparatus.
  • the invention provides a medication cartridge that may be dedicated to a particular medication delivery apparatus.
  • a medication delivery apparatus may take the form of, for example, an injector pen or an infuser apparatus.
  • a medicament delivery apparatus including at least one switch and the medicament cartridge comprising a cartridge housing within which a medicament is provided, a displaceable piston located internally at one end of the housing and a raised ring of material about an external periphery of the medicament cartridge, the ring of material being of sufficient dimensions, in use, to trip the at least one switch of the medicament delivery apparatus.
  • a location of the raised ring of material along a longitudinal axis of the cartridge housing provides an indication of the medicament contained within the medicament cartridge.
  • the raised ring of material may be colour coded to provide an indication of the medicament contained within the medicament cartridge.
  • the raised ring of material is defined by a first inner surface that conforms to a peripheral surface of the cartridge and a second outer surface. More preferably, the second outer surface provides a smooth rounded surface.
  • a shape of the outer surface of the raised ring of material provides an indication of the medicament contained within the medicament cartridge.
  • the medication delivery apparatus further comprises a display, the processor causing the display to show information relating to the medicament cartridge within the medication delivery apparatus.
  • the medication delivery apparatus will not function.
  • FIG. 1 shows a medicament cartridge in accordance with the first aspect of the invention
  • FIG. 2 shows schematically a part of a first medication delivery apparatus for use with a medicament cartridge in accordance with the first aspect of the invention
  • FIG. 3 shows schematically a part of a second medication delivery apparatus for use with a medicament cartridge in accordance with the first aspect of the invention.
  • FIG. 1 there may be seen a medicament cartridge 2 in accordance with the present invention.
  • the medicament cartridge comprises a cartridge housing 4 having an open neck at a first end.
  • the open neck is provided with an external flange.
  • a flexible fluid impermeable membrane 6 is sealingly secured across the neck by a cap 8 secured against the flange.
  • the metal cap 8 has a central opening through which the membrane 6 is exposed. In use, a needle of a needle unit penetrates the membrane 6 .
  • the medicament is contained within a chamber defined by the cartridge housing 4 , the flexible membrane 6 at the first end of the cartridge housing and a displaceable piston 14 (shown in ghost) located at a second end of the cartridge housing 4 . Movement of the piston 14 towards the first end of the cartridge housing 4 causes the medicament to be dispensed through the needle unit.
  • the medicament cartridge of the present invention is additionally provided with a raised ring 10 of material about an external periphery of the cartridge housing 4 .
  • the raised ring 10 of material may be formed of any suitable material by any suitable method.
  • the raised ring 10 of material is defined by a first inner surface that conforms to a peripheral surface of the cartridge housing 4 and a second outer surface 12 .
  • the raised ring 10 is of generally rectangular section.
  • the second outer surface 12 is shown as a smooth rounded surface.
  • the raised ring 10 may be formed as a moulding of a plastics material about the cartridge housing 4 . This may occur prior to filling or loading of the medicament cartridge with medicament. In such a case the location of the raised ring 10 may be used during the filling or loading operation to ensure that the medicament cartridge receives the correct medicament.
  • the location of the raised ring 10 may be used as an indication of the medicament contained within the medicament cartridge.
  • a medicament delivery apparatus may be provided with processor 22 and a switch 20 .
  • the switch 20 When the switch 20 is tripped this allows the medicament delivery apparatus to function. If the switch 20 is not tripped, either because there is no raised ring 10 present, or is present at an incorrect location along a longitudinal axis of the medicament cartridge inserted, such a medicament delivery apparatus will not operate.
  • a medication delivery apparatus may comprise a processor 34 and a plurality of switches 30 , 32 , tripping of a particular switch indicating the presence of a medicament cartridge containing a particular medicament within the medication delivery apparatus.
  • the medication delivery apparatus may further comprise a display 36 , the processor 34 causing the display to show information relating to the medicament cartridge within the medication delivery apparatus, for example whether the medicament is a fast acting or slow acting form of medicament.
  • the processor 34 may actuate a drive mechanism 38 to express medicament from the cartridge 2 .
  • the raised ring 10 may also be formed of a material of a particular colour to indicate a particular medicament within a medicament cartridge. Alternatively, or additionally, the raised 10 may also be formed in a particular shape to indicate a particular medicament within a medicament cartridge. This may be of particular advantage to those having more seriously impaired vision.

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
US10/307,302 2001-12-06 2002-12-02 Medicament cartridge Abandoned US20030109835A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US11/151,209 US7104973B2 (en) 2001-12-06 2005-06-14 Medicament cartridge

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0129187.1 2001-12-06
GBGB0129187.1A GB0129187D0 (en) 2001-12-06 2001-12-06 Improvements in and relating to a medicament cartridge

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/151,209 Continuation US7104973B2 (en) 2001-12-06 2005-06-14 Medicament cartridge

Publications (1)

Publication Number Publication Date
US20030109835A1 true US20030109835A1 (en) 2003-06-12

Family

ID=9927095

Family Applications (2)

Application Number Title Priority Date Filing Date
US10/307,302 Abandoned US20030109835A1 (en) 2001-12-06 2002-12-02 Medicament cartridge
US11/151,209 Expired - Lifetime US7104973B2 (en) 2001-12-06 2005-06-14 Medicament cartridge

Family Applications After (1)

Application Number Title Priority Date Filing Date
US11/151,209 Expired - Lifetime US7104973B2 (en) 2001-12-06 2005-06-14 Medicament cartridge

Country Status (16)

Country Link
US (2) US20030109835A1 (fr)
EP (2) EP1455866B1 (fr)
JP (2) JP2005511155A (fr)
AT (1) ATE369161T1 (fr)
AU (1) AU2002347323B2 (fr)
CA (1) CA2469037C (fr)
CY (1) CY1114486T1 (fr)
DE (1) DE60221701T2 (fr)
DK (2) DK1455866T3 (fr)
ES (2) ES2291513T3 (fr)
GB (1) GB0129187D0 (fr)
IL (2) IL162283A0 (fr)
MX (1) MXPA04005278A (fr)
PT (2) PT1832305E (fr)
SI (1) SI1832305T1 (fr)
WO (1) WO2003047665A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110238017A1 (en) * 2008-12-16 2011-09-29 Panasonic Corporation Medication adminstering device
US20130150786A1 (en) * 2010-04-23 2013-06-13 Sanofi-Aventis Deutschland Gmbh Coded keying insert for a medicament cartridge
US20130211328A1 (en) * 2010-08-13 2013-08-15 Sanofi-Aventis Deutschland Gmbh Differentiation for a drug delivery device

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1309366B1 (fr) 2000-08-10 2007-02-21 Novo Nordisk A/S Dispositif d'administration de medicament avec un support destine a une cartouche
EP1881859B1 (fr) 2005-05-10 2011-01-19 Novo Nordisk A/S Dispositif d'injection comprenant un capteur optique
WO2007039148A1 (fr) * 2005-09-22 2007-04-12 Novo Nordisk A/S Dispositif et procédé pour une détermination de la position absolue sans contact
JP2009530001A (ja) 2006-03-20 2009-08-27 ノボ・ノルデイスク・エー／エス カートリッジの識別コードの非接触読取り
WO2007116090A1 (fr) 2006-04-12 2007-10-18 Novo Nordisk A/S Détermination de position absolue d'élément monté mobile dans un dispositif d'administration de médicaments
AU2007242758B2 (en) 2006-04-26 2012-04-05 Novo Nordisk A/S Contact free absolute position determination of a moving element in a medication delivery device
US8348904B2 (en) 2007-03-21 2013-01-08 Novo Nordisk A/S Medical delivery system having container recognition and container for use with the medical delivery system
US8986253B2 (en) 2008-01-25 2015-03-24 Tandem Diabetes Care, Inc. Two chamber pumps and related methods
US8408421B2 (en) 2008-09-16 2013-04-02 Tandem Diabetes Care, Inc. Flow regulating stopcocks and related methods
AU2009293019A1 (en) 2008-09-19 2010-03-25 Tandem Diabetes Care Inc. Solute concentration measurement device and related methods
TR201808203T4 (tr) 2008-11-06 2018-07-23 Novo Nordisk As Elektronik destekli ilaç aktarım cihazı.
US8764425B2 (en) 2009-02-12 2014-07-01 Picolife Technologies, Llc Mold for making a membrane for use with a flow control system for a micropump
WO2010092156A1 (fr) 2009-02-13 2010-08-19 Novo Nordisk A/S Dispositif médical et cartouche
WO2011003817A1 (fr) * 2009-07-07 2011-01-13 Sanofi-Aventis Deutschland Gmbh Dispositif de délivrance de médicaments comprenant un affichage mécanique ajustable par montage d’une cartouche de médicament
AU2010278894B2 (en) 2009-07-30 2014-01-30 Tandem Diabetes Care, Inc. Infusion pump system with disposable cartridge having pressure venting and pressure feedback
EP2482870B1 (fr) * 2009-09-29 2017-12-27 Admetsys Corporation Système et procédé permettant de différencier des récipients dans l'administration de médicaments
CA2798118A1 (fr) * 2010-05-04 2011-11-10 Sanofi-Aventis Deutschland Gmbh Identification tactile de cartouche remplie de medicament
CN103228305B (zh) * 2010-08-19 2016-06-08 赛诺菲-安万特德国有限公司 使用电子传感器确定与药物容器相关的信息的方法和系统
EP2739256B1 (fr) * 2011-08-02 2016-05-04 Sanofi-Aventis Deutschland GmbH Dispositif d'administration de médicament et cartouche à relier à celui-ci
US8790307B2 (en) 2011-12-01 2014-07-29 Picolife Technologies, Llc Drug delivery device and methods therefor
US8771229B2 (en) 2011-12-01 2014-07-08 Picolife Technologies, Llc Cartridge system for delivery of medicament
CN102566314B (zh) * 2012-01-18 2015-02-11 上海华力微电子有限公司 一种光刻机化学品接口系统及其应用
US10130759B2 (en) 2012-03-09 2018-11-20 Picolife Technologies, Llc Multi-ported drug delivery device having multi-reservoir cartridge system
US9883834B2 (en) 2012-04-16 2018-02-06 Farid Amirouche Medication delivery device with multi-reservoir cartridge system and related methods of use
US9180242B2 (en) 2012-05-17 2015-11-10 Tandem Diabetes Care, Inc. Methods and devices for multiple fluid transfer
US10245420B2 (en) 2012-06-26 2019-04-02 PicoLife Technologies Medicament distribution systems and related methods of use
US9173998B2 (en) 2013-03-14 2015-11-03 Tandem Diabetes Care, Inc. System and method for detecting occlusions in an infusion pump
WO2014145906A2 (fr) 2013-03-15 2014-09-18 Phd Preventative Health Care And Diagnostics, Inc. Dispositif d'administration de médicament prérempli et son procédé de fabrication et d'utilisation
GB201600229D0 (en) * 2016-01-06 2016-02-17 Vicentra B V Fluid delivery system

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5456670A (en) * 1991-06-07 1995-10-10 Liebel-Flarsheim Company Power injector for injecting fluid into animals
US5800397A (en) * 1995-04-20 1998-09-01 Invasatec, Inc. Angiographic system with automatic high/low pressure switching
US6110152A (en) * 1998-01-13 2000-08-29 Minimed Inc. Medication cartridge for an electronic pen-type injector, infusion pump, electronic delivery device, or the like, and method of making the same
US20010041869A1 (en) * 2000-03-23 2001-11-15 Causey James D. Control tabs for infusion devices and methods of using the same
US20020020654A1 (en) * 2000-08-10 2002-02-21 Michael Eilersen Support for a cartridge for transferring an electronically readable item of information from the cartridge to an electronic circuit
US20020134377A1 (en) * 2001-03-20 2002-09-26 Loeffler Joseph P. Fluid filled ampoules and methods for their use in aerosolizers
US6475192B1 (en) * 1992-08-17 2002-11-05 Medrad, Inc. System and method for providing information from a syringe to an injector
US20030065287A1 (en) * 2001-04-03 2003-04-03 Spohn Michael A. Encoding and sensing of syringe information
US20040064101A1 (en) * 2000-12-11 2004-04-01 Kowan Kevin P. Encoding and sensing of syringe information

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69033701T2 (de) * 1990-11-07 2001-07-12 Mdc Investment Holdings, Inc. Nadelvorrichtung mit Mitteln zum Zurückziehen der Nadel
US5322511A (en) * 1992-04-21 1994-06-21 Sterling Winthrop Inc. Portable hand-held power injector
CA2213941C (fr) 1996-09-17 2000-11-28 Becton, Dickinson And Company Porte-cartouche d'insuline fixe pour un stylo injecteur de medicament
WO2001056635A1 (fr) * 2000-02-01 2001-08-09 Disetronic Licensing Ag Contenant et dispositif pour administrer une substance

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5456670A (en) * 1991-06-07 1995-10-10 Liebel-Flarsheim Company Power injector for injecting fluid into animals
US6475192B1 (en) * 1992-08-17 2002-11-05 Medrad, Inc. System and method for providing information from a syringe to an injector
US5800397A (en) * 1995-04-20 1998-09-01 Invasatec, Inc. Angiographic system with automatic high/low pressure switching
US6110152A (en) * 1998-01-13 2000-08-29 Minimed Inc. Medication cartridge for an electronic pen-type injector, infusion pump, electronic delivery device, or the like, and method of making the same
US20010041869A1 (en) * 2000-03-23 2001-11-15 Causey James D. Control tabs for infusion devices and methods of using the same
US20020020654A1 (en) * 2000-08-10 2002-02-21 Michael Eilersen Support for a cartridge for transferring an electronically readable item of information from the cartridge to an electronic circuit
US20040064101A1 (en) * 2000-12-11 2004-04-01 Kowan Kevin P. Encoding and sensing of syringe information
US20020134377A1 (en) * 2001-03-20 2002-09-26 Loeffler Joseph P. Fluid filled ampoules and methods for their use in aerosolizers
US20030065287A1 (en) * 2001-04-03 2003-04-03 Spohn Michael A. Encoding and sensing of syringe information

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110238017A1 (en) * 2008-12-16 2011-09-29 Panasonic Corporation Medication adminstering device
US8771233B2 (en) 2008-12-16 2014-07-08 Atsushi Watanabe Medication administering device
US20130150786A1 (en) * 2010-04-23 2013-06-13 Sanofi-Aventis Deutschland Gmbh Coded keying insert for a medicament cartridge
US9072845B2 (en) * 2010-04-23 2015-07-07 Sanofi-Aventis Deutschland Gmbh Coded keying insert for medicament cartridge
US20130211328A1 (en) * 2010-08-13 2013-08-15 Sanofi-Aventis Deutschland Gmbh Differentiation for a drug delivery device

Also Published As

Publication number Publication date
AU2002347323B2 (en) 2007-11-01
GB0129187D0 (en) 2002-01-23
CA2469037C (fr) 2010-11-16
DE60221701D1 (de) 2007-09-20
EP1455866A1 (fr) 2004-09-15
AU2002347323A1 (en) 2003-06-17
CY1114486T1 (el) 2016-10-05
ES2429901T3 (es) 2013-11-18
JP2009261959A (ja) 2009-11-12
PT1455866E (pt) 2007-11-19
DK1832305T3 (da) 2013-10-14
EP1832305B1 (fr) 2013-07-10
ATE369161T1 (de) 2007-08-15
EP1832305A1 (fr) 2007-09-12
ES2291513T3 (es) 2008-03-01
IL162283A (en) 2010-11-30
US20060106344A1 (en) 2006-05-18
PT1832305E (pt) 2013-09-16
JP2005511155A (ja) 2005-04-28
DK1455866T3 (da) 2007-12-03
US7104973B2 (en) 2006-09-12
MXPA04005278A (es) 2005-03-31
DE60221701T2 (de) 2008-04-30
EP1455866B1 (fr) 2007-08-08
IL162283A0 (en) 2005-11-20
WO2003047665A1 (fr) 2003-06-12
SI1832305T1 (sl) 2013-11-29
CA2469037A1 (fr) 2003-06-12

Similar Documents

Publication Publication Date Title
CA2469037C (fr) Cartouche pour medicaments pourvue de moyens d'identification
AU2002350904B2 (en) Improvements in and relating to a medicament cartridge
US9272094B2 (en) Drug delivery device
EP2201970A1 (fr) Dispositif d'administration de médicaments
US20030125670A1 (en) Relating to a medicament cartridge
MXPA04005274A (es) Mejoras en y relacionadas con un cartucho de medicamento.
US12478735B2 (en) Method and electronic device for acquiring delivery information
CA2425214A1 (fr) Distributeur de medicaments
HK1076406B (en) A medicament cartridge
HK1076262A (en) Improvements in and relating to a medicament cartridge

Legal Events

Date Code Title Description
AS Assignment

Owner name: DCA DESIGN INTERNATIONAL LIMITED, UNITED KINGDOM

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:WOOLSTON, ROBERT;LANGLEY, CHRISTOPHER NIGEL;ADAMS, LEE SIMON;REEL/FRAME:013416/0538

Effective date: 20030120

STCB Information on status: application discontinuation

Free format text: ABANDONED -- FAILURE TO RESPOND TO AN OFFICE ACTION