US1715251A - Disinfecting - Google Patents
Disinfecting Download PDFInfo
- Publication number
- US1715251A US1715251A US77119A US7711925A US1715251A US 1715251 A US1715251 A US 1715251A US 77119 A US77119 A US 77119A US 7711925 A US7711925 A US 7711925A US 1715251 A US1715251 A US 1715251A
- Authority
- US
- United States
- Prior art keywords
- disinfecting
- acid
- ester
- esters
- alkyl ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000000249 desinfective effect Effects 0.000 title description 5
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 10
- 125000005907 alkyl ester group Chemical group 0.000 description 7
- 150000002148 esters Chemical class 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 229940090248 4-hydroxybenzoic acid Drugs 0.000 description 3
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 3
- 239000000344 soap Substances 0.000 description 3
- IJFXRHURBJZNAO-UHFFFAOYSA-N 3-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=CC(O)=C1 IJFXRHURBJZNAO-UHFFFAOYSA-N 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 230000007096 poisonous effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 125000001424 substituent group Chemical group 0.000 description 2
- 125000005274 4-hydroxybenzoic acid group Chemical group 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 210000002969 egg yolk Anatomy 0.000 description 1
- 150000005165 hydroxybenzoic acids Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
Definitions
- Our invention relates to improvements in disinfecting preparations and the process of manufacturing the same, and more particularly in preparations usingan ester of hydroxybenzoic acids as a disinfecting agent. It is known in the art that the esters of the salicylic acid, the alkyl ester as well as the phenyl esters, have disinfecting properties,
- Example- 2.0.05 grammes of an alkyl ester of the metaor parahydroxybenzoic acid are added to 0.5 gramme of sugar and pressed to tablets. After bein dissolvedin water the preparation is use for vaginal cleansing;
- Example 5 To soap containing yolk, such as ray soap, we add 5% of an alkyl ester Since in the ortho compounds the substituents are connected to adjacent carbon atoms in the benzene ring, and since in the metaand paracompounds, the substituents are connected to non-adjacent carbon atoms, the term. non-adjacent hydroxybenzoic acid will hereinafter be used to define the said metaand paracompounds.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
Description
Patented May 28, 1929.
UNITED STATES PATENT "OFFICE."
THEODOR SABALITSCHKA, OF B ERLm-STEGLITZ, AND HEINRICH JAGOBSON,
F BERLIN-113mm, GERMANY;
DISINFE CTIN'G.
No Drawing, Application filed December 22, 1925, Serial No. 77,119, and in Germany December 24,, 1924.
Our invention relates to improvements in disinfecting preparations and the process of manufacturing the same, and more particularly in preparations usingan ester of hydroxybenzoic acids as a disinfecting agent. It is known in the art that the esters of the salicylic acid, the alkyl ester as well as the phenyl esters, have disinfecting properties,
for which reason the said substances have' degree.
We have discovered that only the ester of the orthohydroxybenzoic acid is poisonous, and that non-poisonousdisinfectingpreparations are obtained when using the esters of the meta-or parahydroxybenzoic acids and more particularly the alkyl esters of the said compounds. These alkyl esters of the metaand parahydroxybenzoic acid are odorless and non-poisonous. Further, what is important from a practical pointof view, they are solid crystallizable substances, so that they may be incor orated with preparations such as soaps, liqui s for cleanin the mouth, ointments, pastes, and the like aving hi h disinfecting properties, and having no 0 or or taste of the active disinfecting medium.
Emilmple Jr- 150 grammes of-an alkyl ester .of the meta or parahydroxybenzoic acid.
' the mouth.
Example- 2.0.05 grammes of an alkyl ester of the metaor parahydroxybenzoic acid are added to 0.5 gramme of sugar and pressed to tablets. After bein dissolvedin water the preparation is use for vaginal cleansing;
Example 5.To soap containing yolk, such as ray soap, we add 5% of an alkyl ester Since in the ortho compounds the substituents are connected to adjacent carbon atoms in the benzene ring, and since in the metaand paracompounds, the substituents are connected to non-adjacent carbon atoms, the term. non-adjacent hydroxybenzoic acid will hereinafter be used to define the said metaand paracompounds.
We claim:
1. The herein described improvement in the art of disinfection which comprises applying to the material to be disinfected, a substance containing an ester of a non-adja-. cent hydroxybenzoic acid.
2. The herein described improvement in the art of disinfection which comprises ap- 1 ing to the material to be disinfected, a. substance containing an alkyl ester of a nonadjacent hydroxybenzoic acid.
In testimony whereof we hereunto afiix our signatures.
DB. THEODOR SABALITSCHKA. HEINRICH JACOBSON.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE1715251X | 1924-12-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US1715251A true US1715251A (en) | 1929-05-28 |
Family
ID=7740370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US77119A Expired - Lifetime US1715251A (en) | 1924-12-24 | 1925-12-22 | Disinfecting |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US1715251A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2426276A (en) * | 1939-01-19 | 1947-08-26 | Winthrop Chem Co Inc | Preparations active against cocci infections |
| US2722483A (en) * | 1950-04-13 | 1955-11-01 | Fumol Corp | Method and composition for inhibiting the growth of microorganisms |
| US2724643A (en) * | 1950-12-04 | 1955-11-22 | Shell Dev | Halohydrocarbyl substituted aromatic acids and derivatives thereof |
| US4136165A (en) * | 1976-04-23 | 1979-01-23 | Henkel Kommanditgesellschaft Auf Aktien | Cosmetic preparations with alkoxybenzoic acid esters as inflammation inhibitors and method |
| EP0188026A1 (en) * | 1985-01-03 | 1986-07-23 | Unilever N.V. | Disinfactant compositions |
| WO1993012782A1 (en) * | 1991-10-31 | 1993-07-08 | Elford Howard L | Method of treating viral diseases |
| WO2018223080A1 (en) * | 2017-06-02 | 2018-12-06 | Zurex Pharma, Inc. | Low-alcohol and sterilizable antimicrobial compositions and use thereof |
-
1925
- 1925-12-22 US US77119A patent/US1715251A/en not_active Expired - Lifetime
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2426276A (en) * | 1939-01-19 | 1947-08-26 | Winthrop Chem Co Inc | Preparations active against cocci infections |
| US2722483A (en) * | 1950-04-13 | 1955-11-01 | Fumol Corp | Method and composition for inhibiting the growth of microorganisms |
| US2724643A (en) * | 1950-12-04 | 1955-11-22 | Shell Dev | Halohydrocarbyl substituted aromatic acids and derivatives thereof |
| US4136165A (en) * | 1976-04-23 | 1979-01-23 | Henkel Kommanditgesellschaft Auf Aktien | Cosmetic preparations with alkoxybenzoic acid esters as inflammation inhibitors and method |
| EP0188026A1 (en) * | 1985-01-03 | 1986-07-23 | Unilever N.V. | Disinfactant compositions |
| WO1993012782A1 (en) * | 1991-10-31 | 1993-07-08 | Elford Howard L | Method of treating viral diseases |
| US6248782B1 (en) | 1991-10-31 | 2001-06-19 | Howard L. Elford | Method of treating viral diseases |
| WO2018223080A1 (en) * | 2017-06-02 | 2018-12-06 | Zurex Pharma, Inc. | Low-alcohol and sterilizable antimicrobial compositions and use thereof |
| IL270898B (en) * | 2017-06-02 | 2022-12-01 | Zurex Pharma Inc | Low-alcohol and sterilizable antimicrobial compositions and use thereof |
| IL270898B2 (en) * | 2017-06-02 | 2023-04-01 | Zurex Pharma Inc | Low-alcohol and sterilizable antimicrobial compositions and use thereof |
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