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UA98812C2 - Авирулентная активированная живая вакцина mycoplasma hyopneumoniae - Google Patents

Авирулентная активированная живая вакцина mycoplasma hyopneumoniae

Info

Publication number
UA98812C2
UA98812C2 UAA201005344A UAA201005344A UA98812C2 UA 98812 C2 UA98812 C2 UA 98812C2 UA A201005344 A UAA201005344 A UA A201005344A UA A201005344 A UAA201005344 A UA A201005344A UA 98812 C2 UA98812 C2 UA 98812C2
Authority
UA
Ukraine
Prior art keywords
hyopneumoniae
compositions
adjuvanted
avirulent
live
Prior art date
Application number
UAA201005344A
Other languages
English (en)
Ukrainian (uk)
Inventor
Гсейн-Джу Чу
Жичанг Ху
Вумин ЛИ
Николь Рае Гибсон
Original Assignee
Вайет Ллк
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Вайет Ллк filed Critical Вайет Ллк
Publication of UA98812C2 publication Critical patent/UA98812C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/30—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/116—Polyvalent bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Изобретение относится к композиции для анти-иммунного ответа у животного, где указанная композиция включает иммунологически эффективное количество живого авирулентного штамма, геном которого имеет последовательность нуклеиновой кислоты, которая является по крайней мере на 90 % гомологической последовательностью нуклеиновой кислоты эталонного штамма J, который выбран из штаммов АТСС 25934 и АТСС 27715, и биологически приемлемый адъювант, выбранный из одного или нескольких: SLCD (сульфолипоциклодекстрин), карбопола и SP-Масла. Также данное изобретение относится к способу защиты животных от болезни, ассоциированной с вирулентным штаммомспособу предотвращения или облегчения вспышкии способу усиления иммунного ответа на.
UAA201005344A 2007-11-06 2008-11-05 Авирулентная активированная живая вакцина mycoplasma hyopneumoniae UA98812C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US98581107P 2007-11-06 2007-11-06

Publications (1)

Publication Number Publication Date
UA98812C2 true UA98812C2 (ru) 2012-06-25

Family

ID=40303616

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201005344A UA98812C2 (ru) 2007-11-06 2008-11-05 Авирулентная активированная живая вакцина mycoplasma hyopneumoniae

Country Status (20)

Country Link
US (1) US9056909B2 (ru)
EP (1) EP2217271B1 (ru)
JP (1) JP5869221B2 (ru)
KR (1) KR101225304B1 (ru)
CN (2) CN101883581A (ru)
AR (1) AR069216A1 (ru)
AU (1) AU2008324780A1 (ru)
BR (1) BRPI0820341B1 (ru)
CA (1) CA2704775C (ru)
CL (1) CL2008003304A1 (ru)
CO (1) CO6270337A2 (ru)
DK (1) DK2217271T3 (ru)
HK (1) HK1198289A1 (ru)
ME (1) ME01000B (ru)
MX (1) MX2010005014A (ru)
RU (1) RU2489164C9 (ru)
TW (1) TWI513463B (ru)
UA (1) UA98812C2 (ru)
WO (1) WO2009061798A1 (ru)
ZA (1) ZA201004026B (ru)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
US8444989B1 (en) * 2008-04-18 2013-05-21 Boehringer Ingelheim Vetmedica Gmbh One dose vaccination against mycoplasma infections of pigs
BRPI1010679B1 (pt) * 2009-05-19 2020-09-24 Bioproperties Pty Ltd Cepa de vacina de mycoplasma hyopneumoniae sensível à temperatura e aplicações da mesma, composiçao de vacina, método de preparaçao e uso da mesma
EP2571980A4 (en) * 2010-05-19 2014-02-26 Bioproperties Pty Ltd METHOD RELATED TO A WEAKEN MYCOPLASMA
CN105327344B (zh) * 2011-08-01 2019-03-05 普莱柯生物工程股份有限公司 含有猪圆环病毒2型抗原与副猪嗜血杆菌抗原的疫苗组合物及其制备方法与应用
CN103083658B (zh) * 2011-10-27 2015-09-02 普莱柯生物工程股份有限公司 一种用于治疗或预防猪感染性疾病的疫苗佐剂组合物
CN103157100B (zh) * 2011-12-08 2014-09-24 普莱柯生物工程股份有限公司 副猪嗜血杆菌病、猪链球菌病二联灭活疫苗及其制备方法
CN103157104B (zh) * 2011-12-14 2015-11-18 普莱柯生物工程股份有限公司 猪瘟疫苗的硫代硫酸钠稀释液
BR112014022067B1 (pt) 2012-03-07 2022-05-31 Ceva Sante Animale Composição compreendendo antígeno e lipopolissacarídeo
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
UA114504C2 (uk) * 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
CN104685057B (zh) * 2012-07-10 2019-04-16 海博莱科学有限公司 用于转化猪肺炎支原体的载体，转化的猪肺炎支原体菌株及其用途
EP2684959A1 (en) * 2012-07-10 2014-01-15 Laboratorios Hipra, S.A. Vectors for transforming Mycoplasma hyopneumoniae, transformed M.hyopneumoniae strains, and use thereof
CN103623400B (zh) * 2012-08-24 2016-08-17 普莱柯生物工程股份有限公司 抗猪支原体肺炎、传染性胸膜肺炎疫苗组合物及制备方法
CN103861095B (zh) * 2012-12-11 2016-03-09 普莱柯生物工程股份有限公司 含猪支原体肺炎抗原和猪链球菌病抗原的疫苗组合物及其制备方法和应用
CN110227151B (zh) 2012-12-28 2024-06-14 勃林格殷格翰动物保健有限公司 包含支原体抗原的免疫原性组合物
SG11201505089YA (en) * 2012-12-28 2015-07-30 Boehringer Ingelheim Vetmed Method of making a mycoplasma vaccine
EP2994162B1 (en) 2013-05-08 2021-04-07 Pharmgate Biologics Inc. Vaccine for pcv2 and mycoplasma
CN104338128B (zh) * 2013-07-31 2017-09-05 普莱柯生物工程股份有限公司 一种疫苗组合物及其制备方法和应用
MX2016002903A (es) * 2013-09-05 2016-06-06 Zoetis Services Llc Composiciones inmunogenas de la glicoproteina g de los virus hendra y nipah.
CN104248759B (zh) * 2013-11-19 2017-05-10 普莱柯生物工程股份有限公司 一种疫苗组合物及其制备方法和应用
KR20160099223A (ko) * 2015-02-12 2016-08-22 강원대학교산학협력단 마이코플라스마 하이오뉴모니애 박테린 백신 및 이의 제조방법
US10279031B2 (en) * 2016-05-11 2019-05-07 Phibro Animal Health Corporation Composition comprising antigens and a mucosal adjuvant and a method for using
EP3498847A4 (en) * 2016-08-12 2020-03-04 Innovac VACCINE COMPOSITION FOR PREVENTING SWINE MYCOPLASM INFECTION COMPRISING A RECOMBINANT PROTEIN
CN109234418B (zh) * 2018-11-20 2021-08-13 湖南中净生物科技有限公司 一种鉴别猪肺炎支原体野毒株和疫苗株的引物、试剂盒和方法
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine
US12537071B1 (en) 2020-07-22 2026-01-27 David Gordon Bermudes Bacteria having boolean control pathways expressing therapeutic proteins including immunotherapeutic cytotoxins
CN112143666B (zh) * 2020-09-07 2023-02-21 华中农业大学 一种猪肺炎支原体弱毒株及其在制备弱毒疫苗中的应用
CN119899783B (zh) * 2025-04-02 2025-07-29 华中农业大学 解淀粉芽孢杆菌h-6及其在制备治疗或预防猪繁殖与呼吸综合征病毒感染的药物中的应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917619A (en) 1972-03-06 1975-11-04 Bayer Ag 2-Amino-4,5-dihydropyridine derivatives
JPS5540568B2 (ru) * 1972-10-05 1980-10-18
US4567043A (en) * 1983-06-15 1986-01-28 American Home Products Corporation (Del.) Canine corona virus vaccine
FR2565825B1 (fr) 1984-06-15 1990-07-13 Centre Nat Rech Scient Vaccin contre les maladies dues a des microorganismes tels que des mycoplasmes, sa preparation et membranes de microorganismes en tant que principe actif
US4894332A (en) * 1985-03-27 1990-01-16 Biogen, Inc. DNA sequences coding for Mycoplasma hypopneumoniae surface antigens, methods of use to make the corresponding proteins
JPS62273456A (ja) 1986-05-21 1987-11-27 Tosoh Corp 分析装置用に用いるテストカツプのシ−ル箔破開用シ−ルブレ−カ
JPH0795069B2 (ja) * 1986-05-22 1995-10-11 農林水産省家畜衛生試験場長 マウスＩｇＡ単クローン抗体を用いる豚マイコプラズマ肺炎の診断方法
EP0283840A3 (en) 1987-03-26 1989-08-09 Ml Technology Ventures, L.P. Mycoplasma hyopneumoniae antigen and uses therefor
US5565205A (en) 1990-08-16 1996-10-15 Solvay Animal Health, Inc. Inactivated Mycoplasma hypopneumoniae bacterin and method of use thereof
EP0571648A1 (en) 1992-05-26 1993-12-01 Chung-Nan Weng Vaccine protecting against mycoplasmal pneumonia
BE1008978A5 (fr) 1994-12-27 1996-10-01 Solvay Adjuvants pour vaccins.
GB9622159D0 (en) * 1996-10-24 1996-12-18 Solvay Sociutu Anonyme Polyanionic polymers as adjuvants for mucosal immunization
ZA9710606B (en) * 1996-12-05 1998-06-12 Akzo Nobel Nv Non-virulent Mycoplasma synoviae vaccine thereof.
EP1229929A2 (en) * 1999-11-08 2002-08-14 Biomune VACCINES FOR i MYCOPLASMA BOVIS /i AND METHODS OF USE
US6585981B1 (en) * 2000-07-27 2003-07-01 Regents Of The University Of Minnesota Temperature-sensitive live vaccine for Mycoplasma hyopneumoniae
US7018638B2 (en) 2000-12-19 2006-03-28 Wyeth Mycoplasma hyopneumoniae bacterin vaccine
MY129765A (en) 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
DK2027873T3 (en) * 2001-07-02 2015-11-09 Zoetis Services Llc Single Dose Vaccination with Mycoplasma hyopneumoniae
MXPA03011924A (es) 2001-07-02 2004-03-26 Pfizer Prod Inc Vacuna de micoplasma hyopneumoniae y metodos para reducir la neumonia por mycoplasma bovis en el ganado.
PT1427444E (pt) * 2001-07-27 2013-11-19 Zoetis W Llc Vacina contra o vírus do nilo ocidental
US20030129161A1 (en) * 2001-09-17 2003-07-10 Hsien-Jue Chu Interleukin-12 as a veterinary vaccine adjuvant
US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7279166B2 (en) * 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
AU2003221791A1 (en) 2002-04-05 2003-10-27 Iowa State University Research Foundation, Inc. Mycoplasma polypeptides
TWI350174B (en) * 2003-03-12 2011-10-11 Wyeth Corp Adjuvanted bovine vaccines
RU2278704C2 (ru) * 2004-01-12 2006-06-27 Алексей Борисович Башкиров Метод индукции иммунного ответа организма млекопитающих-2

Also Published As

Publication number Publication date
CA2704775C (en) 2016-05-10
CN104043116A (zh) 2014-09-17
HK1198289A1 (en) 2015-03-27
US9056909B2 (en) 2015-06-16
WO2009061798A1 (en) 2009-05-14
BRPI0820341B1 (pt) 2021-11-09
CL2008003304A1 (es) 2009-01-09
ME01000B (me) 2012-10-20
EP2217271B1 (en) 2016-05-04
BRPI0820341A2 (pt) 2020-05-19
ZA201004026B (en) 2011-04-28
AR069216A1 (es) 2010-01-06
KR101225304B1 (ko) 2013-01-22
RU2010117614A (ru) 2011-12-20
RU2489164C9 (ru) 2014-01-20
JP5869221B2 (ja) 2016-02-24
CA2704775A1 (en) 2009-05-14
EP2217271A1 (en) 2010-08-18
JP2011503086A (ja) 2011-01-27
AU2008324780A1 (en) 2009-05-14
RU2489164C2 (ru) 2013-08-10
KR20100087202A (ko) 2010-08-03
CO6270337A2 (es) 2011-04-20
CN101883581A (zh) 2010-11-10
MX2010005014A (es) 2010-06-30
TW200927166A (en) 2009-07-01
TWI513463B (zh) 2015-12-21
US20090117152A1 (en) 2009-05-07
DK2217271T3 (en) 2016-06-06

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