UA97131C2 - Aminopyrimidine derivatives as plk1 inhibitors - Google Patents
Aminopyrimidine derivatives as plk1 inhibitorsInfo
- Publication number
- UA97131C2 UA97131C2 UAA200907937A UAA200907937A UA97131C2 UA 97131 C2 UA97131 C2 UA 97131C2 UA A200907937 A UAA200907937 A UA A200907937A UA A200907937 A UAA200907937 A UA A200907937A UA 97131 C2 UA97131 C2 UA 97131C2
- Authority
- UA
- Ukraine
- Prior art keywords
- lower alkyl
- alkyl group
- group
- substituted
- hydrogen atom
- Prior art date
Links
- 150000005005 aminopyrimidines Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 101150073897 plk1 gene Proteins 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The present invention relates to a compound represented by Formula [I]: or a pharmaceutically acceptable salt or ester thereof, wherein Rand R, which may be the same or different, are each a hydrogen atom, a halogen atom, a lower alkyl group which may be substituted, or a cyclopropyl group; Rand R, which may be the same or different, are each a hydrogen atom, a lower alkyl group substituted with NRR, a 4- to 6-membered aliphatic heterocyclic group, a lower alkyl group substituted with a 4- to 6-membered aliphatic heterocyclic group, a 5- or 6-membered aromatic heterocyclic group, or a lower alkyl group substituted with a 5- or 6-membered aromatic heterocyclic group; and Ris a hydrogen atom, a cyano group, a halogen atom, or a lower alkyl group., (I)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006356575 | 2006-12-28 | ||
| PCT/JP2007/075224 WO2008081910A1 (en) | 2006-12-28 | 2007-12-20 | Novel aminopyrimidine derivatives as plk1 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA97131C2 true UA97131C2 (en) | 2012-01-10 |
Family
ID=42260455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200907937A UA97131C2 (en) | 2006-12-28 | 2007-12-20 | Aminopyrimidine derivatives as plk1 inhibitors |
Country Status (4)
| Country | Link |
|---|---|
| DO (1) | DOP2009000109A (en) |
| HN (1) | HN2009000964A (en) |
| UA (1) | UA97131C2 (en) |
| ZA (1) | ZA200903127B (en) |
-
2007
- 2007-12-20 UA UAA200907937A patent/UA97131C2/en unknown
-
2009
- 2009-05-06 ZA ZA200903127A patent/ZA200903127B/en unknown
- 2009-05-12 HN HN2009000964A patent/HN2009000964A/en unknown
- 2009-05-12 DO DO2009000109A patent/DOP2009000109A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200903127B (en) | 2010-04-28 |
| DOP2009000109A (en) | 2009-05-31 |
| HN2009000964A (en) | 2011-10-31 |
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