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UA97096C2 - Выделенное антитело, которое специфически связывает рецептор-2 trail (tr-2) - Google Patents

Выделенное антитело, которое специфически связывает рецептор-2 trail (tr-2)

Info

Publication number
UA97096C2
UA97096C2 UAA200804023A UAA200804023A UA97096C2 UA 97096 C2 UA97096 C2 UA 97096C2 UA A200804023 A UAA200804023 A UA A200804023A UA A200804023 A UAA200804023 A UA A200804023A UA 97096 C2 UA97096 C2 UA 97096C2
Authority
UA
Ukraine
Prior art keywords
antibody
specifically binds
trail receptor
isolated antibody
relates
Prior art date
Application number
UAA200804023A
Other languages
English (en)
Ukrainian (uk)
Inventor
Брайан Гліняк
Ксяо-Донг Янг
Шерон Вонг-Медден
Ян Фольтц
Ксяо Фенг
Елісон Фіч
Стівен Фостер
Рендалл Р. Кетчем
Original Assignee
Емджен Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Емджен Інк. filed Critical Емджен Інк.
Priority claimed from PCT/US2006/033763 external-priority patent/WO2007027713A2/en
Publication of UA97096C2 publication Critical patent/UA97096C2/ru

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Изобретение относится к выделенному антителу, которое специфически связывается с рецептором-2 TRAIL (TR-2), полинуклеотиду, который его кодирует, клетке-хозяину, способу получения данного антитела. Изобретение также относится к фармацевтической композиции, которая его содержит, а также к применению терапевтически эффективного количества антитела для изготовления лекарственного средства для лечения рака у пациента.
UAA200804023A 2005-08-31 2006-08-28 Выделенное антитело, которое специфически связывает рецептор-2 trail (tr-2) UA97096C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71343305P 2005-08-31 2005-08-31
PCT/US2006/033763 WO2007027713A2 (en) 2005-08-31 2006-08-28 Trail receptor 2 polypeptides and antibodies

Publications (1)

Publication Number Publication Date
UA97096C2 true UA97096C2 (ru) 2012-01-10

Family

ID=40079598

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200804023A UA97096C2 (ru) 2005-08-31 2006-08-28 Выделенное антитело, которое специфически связывает рецептор-2 trail (tr-2)

Country Status (3)

Country Link
CN (1) CN101300273B (ru)
UA (1) UA97096C2 (ru)
ZA (1) ZA200802575B (ru)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102066403B (zh) * 2009-04-03 2014-10-08 中国医学科学院基础医学研究所 抗人死亡受体dr5单克隆抗体ad5-10所识别的抗原决定簇、其衍生物及其用途
WO2011130324A1 (en) * 2010-04-13 2011-10-20 Medimmune, Llc Fibronectin type iii domain-based multimeric scaffolds
CA2877573A1 (en) * 2012-06-21 2013-12-27 Sorrento Therapeutics, Inc. Antigen binding proteins that bind c-met
CN103333247B (zh) * 2013-05-30 2014-10-08 北京东方百泰生物科技有限公司 新型抗vegfr2的单克隆抗体及其制备与应用
CN106632607A (zh) * 2016-12-29 2017-05-10 华东理工大学 靶向survivin纳米抗体及其制备方法和应用
CN108855003B (zh) * 2018-06-28 2021-01-05 南开大学 一种用于清除血液中炎性因子的免疫吸附剂及其制备方法
CN114395034B (zh) * 2022-03-24 2022-08-05 中国科学院微生物研究所 一种高效中和新型冠状病毒的人源抗体及其应用
EP4653468A1 (en) * 2023-01-17 2025-11-26 Suzhou Youthen Biotechnology Co., Ltd Dr5 domain variant and use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI318983B (en) * 2000-05-02 2010-01-01 Uab Research Foundation An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
JP2005516958A (ja) * 2001-12-20 2005-06-09 ヒューマン　ジノーム　サイエンシーズ，　インコーポレイテッド Ｔｒａｉｌレセプターに免疫特異的に結合する抗体

Also Published As

Publication number Publication date
CN101300273A (zh) 2008-11-05
CN101300273B (zh) 2013-05-22
ZA200802575B (en) 2009-01-28

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