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Application filed by Тракон Фармасютикалс, Инк.filedCriticalТракон Фармасютикалс, Инк.
Publication of UA96614C2publicationCriticalpatent/UA96614C2/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
Compositions and methods useful in the treatment of certain cancers. The methods include administering to a patient receiving an antifolate anticancer agent, methoxyamine administered in an amount sufficient to enhance or increase the effect of the antifolate anticancer agent. In part, this application is based on the recognition that certain molecules that target abasic lesions or AP sites in DNA improve, augment, or potentiate the chemotherapeutic efficacy of certain anticancer agents.
UAA200907128A2006-12-292007-12-21Combinations of antifolate agent in the treatment of cancer
UA96614C2
(en)