UA95224C2 - Антацидная фармацевтическая композиция в порошковой форме, фармацевтическое средство, ее содержащее, и способ ее получения - Google Patents
Антацидная фармацевтическая композиция в порошковой форме, фармацевтическое средство, ее содержащее, и способ ее полученияInfo
- Publication number
- UA95224C2 UA95224C2 UAA200706189A UAA200706189A UA95224C2 UA 95224 C2 UA95224 C2 UA 95224C2 UA A200706189 A UAA200706189 A UA A200706189A UA A200706189 A UAA200706189 A UA A200706189A UA 95224 C2 UA95224 C2 UA 95224C2
- Authority
- UA
- Ukraine
- Prior art keywords
- acid
- sodium alginate
- powder form
- pharmaceutical composition
- inhibitor
- Prior art date
Links
- 230000001458 anti-acid effect Effects 0.000 title abstract 6
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000000843 powder Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 4
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 abstract 3
- 235000010413 sodium alginate Nutrition 0.000 abstract 3
- 229940005550 sodium alginate Drugs 0.000 abstract 3
- 239000000661 sodium alginate Substances 0.000 abstract 3
- 102100021904 Potassium-transporting ATPase alpha chain 1 Human genes 0.000 abstract 2
- 108010083204 Proton Pumps Proteins 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000006185 dispersion Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 235000003599 food sweetener Nutrition 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 239000003186 pharmaceutical solution Substances 0.000 abstract 1
- 239000007971 pharmaceutical suspension Substances 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 239000003765 sweetening agent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Изобретение касается антацидной фармацевтической композиции для быстрой и продолжительной нейтрализации кислотности желудка с защитным действием по отношению к слизистой оболочке желудка в виде порошка, для приготовления, путем растворения в воде, фармацевтического раствора или суспензии для перорального применения. Композиция содержит альгинат натрия, растворимый антацидный агент или комбинацию антацидов, ингибитор протонного насоса, разбавитель и подсластители, где (а) от 20 % до 30 % альгината натрия, присутствующего в композиции вместе с суммарным количеством ингибитора протонного насоса, гомогенно распределены по поверхности всего антацидного агента или комбинации антацидов композиции, и (b) другое количество, близко 70 %, альгината натрия, присутствующего в композиции, имеет влажность менее 2 %.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ARP060102333A AR056062A1 (es) | 2006-06-05 | 2006-06-05 | Composicion farmaceutica antiacida en forma de polvo, preparacion farmaceutica que la comprende y proceso para su preparacion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA95224C2 true UA95224C2 (ru) | 2011-07-25 |
Family
ID=38572778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200706189A UA95224C2 (ru) | 2006-06-05 | 2007-06-04 | Антацидная фармацевтическая композиция в порошковой форме, фармацевтическое средство, ее содержащее, и способ ее получения |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7968118B2 (ru) |
| EP (1) | EP1905426B1 (ru) |
| AR (1) | AR056062A1 (ru) |
| BR (1) | BRPI0704028B8 (ru) |
| DE (1) | DE07380159T1 (ru) |
| ES (1) | ES2301455T3 (ru) |
| MX (1) | MX2007006722A (ru) |
| PL (1) | PL1905426T3 (ru) |
| RU (1) | RU2351332C2 (ru) |
| UA (1) | UA95224C2 (ru) |
| UY (1) | UY30382A1 (ru) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008019339A1 (de) * | 2008-04-16 | 2009-10-22 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Zusammensetzung für die medizinische Anwendung, insbesondere Antazidum |
| AU2011242177B8 (en) * | 2010-04-23 | 2015-06-04 | S-Biotek Holding Aps | A solid pharmaceutical composition for neutralizing stomach acid |
| EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| TR201723199A2 (tr) * | 2017-12-30 | 2019-07-22 | Neutec Ar Ge Sanayi Ve Ticaret Anonim Sirketi | Yeni farmasötik bileşimler. |
| TW202126301A (zh) * | 2019-10-04 | 2021-07-16 | 愛爾蘭商席歐拉斯製藥有限公司 | 小兒懸浮調配物 |
| FR3107183B1 (fr) * | 2020-02-19 | 2022-04-29 | Amsellem Jean Paul | Composition pour le traitement des vertiges |
| CN114288243B (zh) * | 2022-01-24 | 2023-02-07 | 中国药科大学 | 一种口服抗酸原位凝胶及其制备方法和应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4744986A (en) * | 1986-03-07 | 1988-05-17 | Rorer Pharmaceutical Corporation | Process for the preparation of a viscosity-stable antacid composition |
| GB2189698A (en) | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
| AU7218294A (en) * | 1993-07-06 | 1995-02-06 | Mcneil-Ppc, Inc. | H2 antagonist-alginate combinations |
| SE9600071D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients I |
| WO1998023272A1 (en) * | 1996-11-27 | 1998-06-04 | The Procter & Gamble Company | Compositions and methods for the treatment of gastrointestinal disorders |
| BR0300882A (pt) * | 2003-04-09 | 2005-05-10 | Cmax Otimizacao De Resultados | Composições farmacêuticas, método e uso de formulação para tratamento e prevenção de infecções associadas com helicobacter pylori em mamìferos e no ser humano |
| CA2531566C (en) * | 2003-07-18 | 2013-05-07 | Santarus, Inc. | Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders |
| EP1667681A4 (en) * | 2003-10-03 | 2009-09-30 | Astron Res Pvt Ltd | NEW TRANSMUCOSAL ADMINISTRATION SYSTEM |
-
2006
- 2006-06-05 AR ARP060102333A patent/AR056062A1/es not_active Application Discontinuation
-
2007
- 2007-05-31 UY UY30382A patent/UY30382A1/es active IP Right Grant
- 2007-06-01 DE DE07380159T patent/DE07380159T1/de active Pending
- 2007-06-01 PL PL07380159T patent/PL1905426T3/pl unknown
- 2007-06-01 EP EP07380159A patent/EP1905426B1/en active Active
- 2007-06-01 ES ES07380159T patent/ES2301455T3/es active Active
- 2007-06-04 RU RU2007120753/15A patent/RU2351332C2/ru active
- 2007-06-04 BR BRPI0704028A patent/BRPI0704028B8/pt active IP Right Grant
- 2007-06-04 UA UAA200706189A patent/UA95224C2/ru unknown
- 2007-06-05 MX MX2007006722A patent/MX2007006722A/es active IP Right Grant
- 2007-06-05 US US11/810,453 patent/US7968118B2/en not_active Expired - Fee Related
-
2009
- 2009-12-21 US US12/643,095 patent/US8093271B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20100160382A1 (en) | 2010-06-24 |
| MX2007006722A (es) | 2009-02-18 |
| BRPI0704028B8 (pt) | 2022-05-10 |
| ES2301455T3 (es) | 2013-01-23 |
| BRPI0704028B1 (pt) | 2021-02-09 |
| RU2007120753A (ru) | 2008-12-10 |
| BRPI0704028A (pt) | 2008-04-01 |
| RU2351332C2 (ru) | 2009-04-10 |
| PL1905426T3 (pl) | 2013-02-28 |
| EP1905426B1 (en) | 2012-09-05 |
| EP1905426A3 (en) | 2008-05-21 |
| EP1905426A2 (en) | 2008-04-02 |
| US20070281015A1 (en) | 2007-12-06 |
| DE07380159T1 (de) | 2008-08-21 |
| US7968118B2 (en) | 2011-06-28 |
| ES2301455T1 (es) | 2008-07-01 |
| US8093271B2 (en) | 2012-01-10 |
| UY30382A1 (es) | 2007-07-31 |
| AR056062A1 (es) | 2007-09-19 |
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