UA95502C2 - Compounds and compositions as channel activating protease inhibitors - Google Patents
Compounds and compositions as channel activating protease inhibitorsInfo
- Publication number
- UA95502C2 UA95502C2 UAA200906745A UAA200906745A UA95502C2 UA 95502 C2 UA95502 C2 UA 95502C2 UA A200906745 A UAA200906745 A UA A200906745A UA A200906745 A UAA200906745 A UA A200906745A UA 95502 C2 UA95502 C2 UA 95502C2
- Authority
- UA
- Ukraine
- Prior art keywords
- compounds
- channel activating
- compositions
- protease inhibitors
- activating protease
- Prior art date
Links
- 230000003213 activating effect Effects 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title 1
- 101000798702 Homo sapiens Transmembrane protease serine 4 Proteins 0.000 abstract 3
- 102100032471 Transmembrane protease serine 4 Human genes 0.000 abstract 3
- 101000598054 Homo sapiens Transmembrane protease serine 11B Proteins 0.000 abstract 2
- 108091005804 Peptidases Proteins 0.000 abstract 2
- 239000004365 Protease Substances 0.000 abstract 2
- 102100037942 Suppressor of tumorigenicity 14 protein Human genes 0.000 abstract 2
- 102100037023 Transmembrane protease serine 11B Human genes 0.000 abstract 2
- 102100022046 Brain-specific serine protease 4 Human genes 0.000 abstract 1
- 108010059081 Cathepsin A Proteins 0.000 abstract 1
- 102000005572 Cathepsin A Human genes 0.000 abstract 1
- 101000897856 Homo sapiens Adenylyl cyclase-associated protein 2 Proteins 0.000 abstract 1
- 101000896891 Homo sapiens Brain-specific serine protease 4 Proteins 0.000 abstract 1
- 101000836079 Homo sapiens Serpin B8 Proteins 0.000 abstract 1
- 101000836075 Homo sapiens Serpin B9 Proteins 0.000 abstract 1
- 101000661807 Homo sapiens Suppressor of tumorigenicity 14 protein Proteins 0.000 abstract 1
- 101000798707 Homo sapiens Transmembrane protease serine 13 Proteins 0.000 abstract 1
- 101000638154 Homo sapiens Transmembrane protease serine 2 Proteins 0.000 abstract 1
- 101000798700 Homo sapiens Transmembrane protease serine 3 Proteins 0.000 abstract 1
- 108010028275 Leukocyte Elastase Proteins 0.000 abstract 1
- 108010091175 Matriptase Proteins 0.000 abstract 1
- 101100069392 Mus musculus Gzma gene Proteins 0.000 abstract 1
- 102100033174 Neutrophil elastase Human genes 0.000 abstract 1
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 102100029500 Prostasin Human genes 0.000 abstract 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 1
- 102100032467 Transmembrane protease serine 13 Human genes 0.000 abstract 1
- 102100031989 Transmembrane protease serine 2 Human genes 0.000 abstract 1
- 108090000631 Trypsin Proteins 0.000 abstract 1
- 102000004142 Trypsin Human genes 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108010031970 prostasin Proteins 0.000 abstract 1
- 239000012588 trypsin Substances 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention provides compounds and pharmaceutical compositions thereof, which are useful for modulating channel activating proteases, and methods for, using such compounds to treat, ameliorate or prevent a condition associated with a channel activating protease, including but not limited to prostasin, PRSS22, TMPRSS11 (e.g., TMPRSS11B, TMPRSS11B), TMPRSS2, TMPRSS3, TMPRSS4 (MTSP-2), matriptase (MTSP-1), CAP2, CAP3, trypsin, cathepsin A, or neutrophil elastase.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88433407P | 2007-01-10 | 2007-01-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA95502C2 true UA95502C2 (en) | 2011-08-10 |
Family
ID=41272770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200906745A UA95502C2 (en) | 2007-01-10 | 2007-11-21 | Compounds and compositions as channel activating protease inhibitors |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN101578120A (en) |
| SI (1) | SI2104535T1 (en) |
| UA (1) | UA95502C2 (en) |
| ZA (1) | ZA200904414B (en) |
-
2007
- 2007-11-21 SI SI200730542T patent/SI2104535T1/en unknown
- 2007-11-21 UA UAA200906745A patent/UA95502C2/en unknown
- 2007-11-21 CN CNA2007800493558A patent/CN101578120A/en active Pending
-
2009
- 2009-06-24 ZA ZA200904414A patent/ZA200904414B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200904414B (en) | 2010-04-28 |
| SI2104535T1 (en) | 2011-04-29 |
| CN101578120A (en) | 2009-11-11 |
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