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UA94628C2 - Humanized monoclonal antibody that binds to steap-1 and use thereof - Google Patents

Humanized monoclonal antibody that binds to steap-1 and use thereof

Info

Publication number
UA94628C2
UA94628C2 UAA200905270A UAA200905270A UA94628C2 UA 94628 C2 UA94628 C2 UA 94628C2 UA A200905270 A UAA200905270 A UA A200905270A UA A200905270 A UAA200905270 A UA A200905270A UA 94628 C2 UA94628 C2 UA 94628C2
Authority
UA
Ukraine
Prior art keywords
steap
monoclonal antibody
humanized monoclonal
binds
antibody
Prior art date
Application number
UAA200905270A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Майкл С. Деннис
Бонни РУБИНФЕЛД
Пол Полакис
Айя Якобовиц
Original Assignee
Дженентек, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Дженентек, Инк. filed Critical Дженентек, Инк.
Publication of UA94628C2 publication Critical patent/UA94628C2/en

Links

Landscapes

  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention relates to a humanized monoclonal antibody that specifically binds to STEAP-1. The invention further relates to a method of detecting the presence of STEAP- a biological sample, an immunoconjugate comprising the antibody, a pharmaceutical formulation, a method of inhibiting cellular proliferation etc.
UAA200905270A 2006-10-27 2007-10-26 Humanized monoclonal antibody that binds to steap-1 and use thereof UA94628C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86329506P 2006-10-27 2006-10-27

Publications (1)

Publication Number Publication Date
UA94628C2 true UA94628C2 (en) 2011-05-25

Family

ID=41232249

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200905270A UA94628C2 (en) 2006-10-27 2007-10-26 Humanized monoclonal antibody that binds to steap-1 and use thereof

Country Status (4)

Country Link
CN (1) CN101573384B (en)
SI (1) SI2061814T1 (en)
UA (1) UA94628C2 (en)
ZA (1) ZA200902161B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11180571B2 (en) 2017-04-03 2021-11-23 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1

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KR20130098165A (en) * 2010-06-03 2013-09-04 제넨테크, 인크. Immuno-pet imaging of antibodies and immunoconjugates and uses therefor
CA2807269A1 (en) * 2010-08-24 2012-03-01 Roche Glycart Ag Activatable bispecific antibodies
US8987209B2 (en) * 2010-09-29 2015-03-24 Seattle Genetics, Inc. N-carboxyalkyl-auristatin and the use thereof
WO2013150623A1 (en) * 2012-04-04 2013-10-10 株式会社ペルセウスプロテオミクス Conjugate of anti-cdh3 (p-cadherin) antibody and drug
RU2016130349A (en) * 2014-01-24 2018-03-01 Дженентек, Инк. WAYS OF APPLICATION OF ANTIBODIES AGAINST STEAP1 AND IMMUNOCONJUGATES
MX378281B (en) * 2014-04-25 2025-03-10 Pf Medicament DRUG-ANTIBODY CONJUGATE AND ITS USE FOR CANCER TREATMENT.
EP3165237B1 (en) 2015-11-03 2018-12-19 Industrial Technology Research Institute Antibody-drug conjugate (adc) and method for forming the same
CN113599533A (en) 2015-11-25 2021-11-05 乐高化学生物科学股份有限公司 Antibody-drug conjugates comprising branched linkers and methods related thereto
KR101938800B1 (en) 2017-03-29 2019-04-10 주식회사 레고켐 바이오사이언스 Pyrrolobenzodiazepine dimer prodrug and its ligand-linker conjugate compound
CN107167541B (en) * 2017-07-08 2019-08-02 万舒（北京）医药科技有限公司 The method for measuring the DTPA-Zn in rat plasma biological sample
JP7459063B2 (en) 2018-05-09 2024-04-01 レゴケム バイオサイエンシズ， インク． Compositions and methods related to anti-CD19 antibody drug conjugates
CN119185572A (en) 2018-09-26 2024-12-27 江苏恒瑞医药股份有限公司 Ligand-drug conjugate of irinotecan analogue, preparation method and application thereof
KR102503143B1 (en) * 2019-03-06 2023-02-24 주식회사 레고켐 바이오사이언스 Antibody-drug conjugate comprising antibody against human DLK1 and its use
EP3950716A4 (en) 2019-04-01 2022-11-09 Jiangsu Hengrui Medicine Co., Ltd. ANTI-CLAUDINE 18.2 ANTIBODIES AND USE
US20230013784A1 (en) 2019-06-26 2023-01-19 Jiangsu Hengrui Medicine Co., Ltd. Anti-cea antibody and application thereof
EP4025609A4 (en) * 2019-09-05 2023-10-04 Memorial Sloan Kettering Cancer Center ANTI-STEAP1 ANTIBODIES AND USES THEREOF
BR112022004913A2 (en) 2019-09-18 2022-06-07 Baili Bio Chengdu Pharmaceutical Co Ltd Camptothecin derivative and conjugate thereof
JP2023532197A (en) 2020-06-30 2023-07-27 江蘇恒瑞医薬股▲ふん▼有限公司 Anti-CD70 antibody and its application
AU2021360625A1 (en) 2020-10-14 2023-06-01 Jiangsu Hengrui Pharmaceuticals Co., Ltd. Anti-her3 antibody and anti-her3 antibody-drug conjugate and medical use thereof
CN112924665B (en) * 2021-02-19 2023-10-03 山东莱博生物科技有限公司 Antibody horseradish peroxidase marker and preparation and application thereof
EP4144376A4 (en) 2021-07-19 2023-09-20 MabPlex International Co., Ltd. Antibody drug conjugate loaded with double toxins and application thereof
CN117295526B (en) * 2021-09-10 2025-11-18 上海药明合联生物技术有限公司 Methods for preparing highly homogeneous antibody-drug conjugates of engineered antibodies
WO2024049931A1 (en) 2022-09-02 2024-03-07 Merck Sharp & Dohme Llc Exatecan-derived topoisomerase-1 inhibitors pharmaceutical compositions, and uses thereof
EP4633681A1 (en) 2022-12-14 2025-10-22 Merck Sharp & Dohme LLC Auristatin linker-payloads, pharmaceutical compositions, and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8008442B2 (en) * 2004-04-22 2011-08-30 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
KR101270829B1 (en) * 2004-09-23 2013-06-07 제넨테크, 인크. Cystein engineered antibodies and conjugates

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11180571B2 (en) 2017-04-03 2021-11-23 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1
US11685790B2 (en) 2017-04-03 2023-06-27 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1
US12129306B2 (en) 2017-04-03 2024-10-29 Hoffman-La Roche Inc. Antibodies binding to STEAP-1

Also Published As

Publication number Publication date
SI2061814T1 (en) 2012-09-28
CN101573384B (en) 2013-02-20
CN101573384A (en) 2009-11-04
ZA200902161B (en) 2010-06-30

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