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UA94417C2 - Замещенные 7-азаиндазолы, композиция, которая их содержит, и применение - Google Patents

Замещенные 7-азаиндазолы, композиция, которая их содержит, и применение

Info

Publication number
UA94417C2
UA94417C2 UAA200802787A UAA200802787A UA94417C2 UA 94417 C2 UA94417 C2 UA 94417C2 UA A200802787 A UAA200802787 A UA A200802787A UA A200802787 A UAA200802787 A UA A200802787A UA 94417 C2 UA94417 C2 UA 94417C2
Authority
UA
Ukraine
Prior art keywords
indazoles
containing same
production method
composition containing
substituted aza
Prior art date
Application number
UAA200802787A
Other languages
English (en)
Ukrainian (uk)
Inventor
Кирстен Бьергард
Анил Наир
Марсель Патек
Марк Додсон
Марта Аккерман-Беррьер
Мартин Смрчина
Венсан Леруа
Эрик Бак
Мишель Табар
Батист Ронан
Фабрис Вивьяни
Катрин Суай
Original Assignee
Авентис Фарма С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Авентис Фарма С.А. filed Critical Авентис Фарма С.А.
Publication of UA94417C2 publication Critical patent/UA94417C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Данное изобретение касается новых специфических 7-азаиндолов формулы (I), которые имеют активность, которая модулирует активность белков, в частности киназ, композиций, которые их содержат, и их применения как лекарственного средства, особенно как противораковых средств.(I)
UAA200802787A 2005-08-04 2006-08-01 Замещенные 7-азаиндазолы, композиция, которая их содержит, и применение UA94417C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0508316A FR2889526B1 (fr) 2005-08-04 2005-08-04 7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
UA94417C2 true UA94417C2 (ru) 2011-05-10

Family

ID=36177926

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200802787A UA94417C2 (ru) 2005-08-04 2006-08-01 Замещенные 7-азаиндазолы, композиция, которая их содержит, и применение

Country Status (29)

Country Link
US (1) US8058290B2 (ru)
EP (1) EP1912988B1 (ru)
JP (1) JP5128475B2 (ru)
KR (1) KR101263970B1 (ru)
CN (2) CN102093353B (ru)
AR (1) AR057719A1 (ru)
AU (1) AU2006277855B2 (ru)
BR (1) BRPI0614304A2 (ru)
CA (1) CA2617293C (ru)
CR (1) CR9678A (ru)
DO (1) DOP2006000179A (ru)
EA (1) EA019302B1 (ru)
EC (1) ECSP088152A (ru)
FR (1) FR2889526B1 (ru)
HN (1) HN2008000188A (ru)
IL (1) IL188792A0 (ru)
MA (1) MA29652B1 (ru)
MX (1) MX2008001614A (ru)
MY (1) MY147488A (ru)
NI (1) NI200800020A (ru)
NO (1) NO20081013L (ru)
NZ (1) NZ565396A (ru)
PE (1) PE20070240A1 (ru)
TN (1) TNSN08024A1 (ru)
TW (1) TWI378930B (ru)
UA (1) UA94417C2 (ru)
UY (1) UY29727A1 (ru)
WO (1) WO2007017577A1 (ru)
ZA (1) ZA200800965B (ru)

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RU2671864C2 (ru) * 2013-03-13 2018-11-07 Санофи N-(4-(азаиндазол-6-ил)-фенил)-сульфонамиды и их применение в качестве лекарственных средств

Also Published As

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AU2006277855B2 (en) 2012-08-23
BRPI0614304A2 (pt) 2011-03-22
TWI378930B (en) 2012-12-11
KR20080031939A (ko) 2008-04-11
TNSN08024A1 (en) 2009-07-14
MA29652B1 (fr) 2008-07-01
UY29727A1 (es) 2007-02-28
KR101263970B1 (ko) 2013-05-13
EP1912988B1 (fr) 2014-04-16
US8058290B2 (en) 2011-11-15
CA2617293A1 (fr) 2007-02-15
CN101304998B (zh) 2012-09-05
FR2889526A1 (fr) 2007-02-09
MY147488A (en) 2012-12-14
JP5128475B2 (ja) 2013-01-23
WO2007017577A1 (fr) 2007-02-15
ZA200800965B (en) 2009-11-25
CA2617293C (fr) 2015-09-22
CN102093353B (zh) 2013-06-12
ECSP088152A (es) 2008-02-20
CN101304998A (zh) 2008-11-12
PE20070240A1 (es) 2007-04-12
HK1125928A1 (en) 2009-08-21
JP2009503037A (ja) 2009-01-29
AR057719A1 (es) 2007-12-12
DOP2006000179A (es) 2007-03-31
NZ565396A (en) 2011-03-31
EA019302B1 (ru) 2014-02-28
US20080182844A1 (en) 2008-07-31
AU2006277855A1 (en) 2007-02-15
IL188792A0 (en) 2008-08-07
CR9678A (es) 2008-09-22
NI200800020A (es) 2011-01-10
HN2008000188A (es) 2010-11-09
MX2008001614A (es) 2008-04-04
NO20081013L (no) 2008-04-14
FR2889526B1 (fr) 2012-02-17
EP1912988A1 (fr) 2008-04-23
CN102093353A (zh) 2011-06-15
EA200800514A1 (ru) 2008-06-30
TW200745103A (en) 2007-12-16

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