UA93348C2 - Индазолы, бензотиазолы, бензоизотиазолы, их получение и применение - Google Patents
Индазолы, бензотиазолы, бензоизотиазолы, их получение и применениеInfo
- Publication number
- UA93348C2 UA93348C2 UAA200611224A UAA200611224A UA93348C2 UA 93348 C2 UA93348 C2 UA 93348C2 UA A200611224 A UAA200611224 A UA A200611224A UA A200611224 A UAA200611224 A UA A200611224A UA 93348 C2 UA93348 C2 UA 93348C2
- Authority
- UA
- Ukraine
- Prior art keywords
- indazoles
- benzothiazoles
- receptors
- nach
- benzoisothiazoles
- Prior art date
Links
- IOJUPLGTWVMSFF-UHFFFAOYSA-N benzothiazole Chemical class C1=CC=C2SC=NC2=C1 IOJUPLGTWVMSFF-UHFFFAOYSA-N 0.000 title abstract 2
- 150000002473 indoazoles Chemical class 0.000 title abstract 2
- CSNIZNHTOVFARY-UHFFFAOYSA-N 1,2-benzothiazole Chemical class C1=CC=C2C=NSC2=C1 CSNIZNHTOVFARY-UHFFFAOYSA-N 0.000 title 1
- 150000008316 benzisoxazoles Chemical class 0.000 title 1
- 102000019315 Nicotinic acetylcholine receptors Human genes 0.000 abstract 5
- 108050006807 Nicotinic acetylcholine receptors Proteins 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000003446 ligand Substances 0.000 abstract 2
- 230000004913 activation Effects 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Данное изобретение в целом касается области лигандов никотиновых ацетилхолиновых рецепторов (рецепторов nACh), активации рецепторов nACh и лечения патологических состояний, связанных с дефектными или неправильно функционирующими никотиновыми ацетилхолиновыми рецепторами, особенно в головном мозге. Кроме того, в заявке описаны соединения (например, индазолы и бензотиазолы), которые действуют как лиганды для подтипа (7 рецепторов nACh, способы получения таких соединений и их применение.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55595104P | 2004-03-25 | 2004-03-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA93348C2 true UA93348C2 (ru) | 2011-02-10 |
Family
ID=38693326
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200611224A UA93348C2 (ru) | 2004-03-25 | 2005-03-25 | Индазолы, бензотиазолы, бензоизотиазолы, их получение и применение |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN101001856A (ru) |
| TN (1) | TNSN06301A1 (ru) |
| UA (1) | UA93348C2 (ru) |
| ZA (1) | ZA200608812B (ru) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20130213B1 (ar) | 2012-07-17 | 2021-08-17 | Takeda Pharmaceuticals Co | معارضات لمستقبلht3-5 |
| PT3201203T (pt) | 2014-09-29 | 2021-08-09 | Takeda Pharmaceuticals Co | Forma cristalina de 1-(1-metil-1h-pirazol-4-il)-n-((1r,5s,7s)-9-metil-3-oxa-9-azabiciclo[3.3.1]nonan-7-il)-1hindol-3-carboxamida |
| JP7123429B2 (ja) * | 2017-05-04 | 2022-08-23 | シャンハイ ロングウッド バイオファルマシューティカルズ カンパニー リミテッド | 二環式縮合環系ヌクレオカプシド阻害剤および薬物としてｂ型肝炎を治療するためのその使用 |
| AU2019224075A1 (en) | 2018-02-23 | 2020-09-10 | Samumed, Llc | 5-heteroaryl substituted indazole-3-carboxamides and preparation and use thereof |
| CN110437132B (zh) * | 2018-05-04 | 2022-04-01 | 上海长森药业有限公司 | 双并杂环核衣壳抑制剂及其药物用途 |
| CN114605329B (zh) * | 2022-03-28 | 2024-01-26 | 河南中医药大学 | 取代的吲唑甲酰胺或取代的氮杂吲唑甲酰胺类flt3抑制剂及其用途 |
-
2005
- 2005-03-25 CN CN 200580016742 patent/CN101001856A/zh active Pending
- 2005-03-25 UA UAA200611224A patent/UA93348C2/ru unknown
-
2006
- 2006-09-22 TN TNP2006000301A patent/TNSN06301A1/en unknown
- 2006-10-23 ZA ZA200608812A patent/ZA200608812B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN06301A1 (en) | 2007-12-03 |
| ZA200608812B (en) | 2008-04-30 |
| CN101001856A (zh) | 2007-07-18 |
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