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UA92132C2 - Высокоактивные рекомбинантные вирусы гриппа для вакцин и генотерапии - Google Patents

Высокоактивные рекомбинантные вирусы гриппа для вакцин и генотерапии

Info

Publication number
UA92132C2
UA92132C2 UAA200512619A UAA200512619A UA92132C2 UA 92132 C2 UA92132 C2 UA 92132C2 UA A200512619 A UAA200512619 A UA A200512619A UA A200512619 A UAA200512619 A UA A200512619A UA 92132 C2 UA92132 C2 UA 92132C2
Authority
UA
Ukraine
Prior art keywords
influenza viruses
high titer
vaccines
gene therapy
recombinant influenza
Prior art date
Application number
UAA200512619A
Other languages
English (en)
Ukrainian (uk)
Inventor
Йосихиро Каваока
Original Assignee
Висконсин Алюмни Рисьёч Фаундейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Висконсин Алюмни Рисьёч Фаундейшн filed Critical Висконсин Алюмни Рисьёч Фаундейшн
Publication of UA92132C2 publication Critical patent/UA92132C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/08—Clostridium, e.g. Clostridium tetani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16141—Use of virus, viral particle or viral elements as a vector
    • C12N2760/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Physics & Mathematics (AREA)
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  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение относится к композиции, векторам вируса гриппа для продуцирования молекул "минус-нитевой" и " плюс-нитевой" РНК, пригодной для получения высокоактивных вирусов гриппа. Также изобретение относится к способу получения "6+2" реассортативных вирусов гриппа с применением клонированных кДНК и обратной генетики.
UAA200512619A 2003-05-28 2004-05-27 Высокоактивные рекомбинантные вирусы гриппа для вакцин и генотерапии UA92132C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47379803P 2003-05-28 2003-05-28

Publications (1)

Publication Number Publication Date
UA92132C2 true UA92132C2 (ru) 2010-10-11

Family

ID=33539054

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200512619A UA92132C2 (ru) 2003-05-28 2004-05-27 Высокоактивные рекомбинантные вирусы гриппа для вакцин и генотерапии

Country Status (18)

Country Link
US (1) US8475806B2 (ru)
EP (1) EP1631663B1 (ru)
JP (2) JP5215561B2 (ru)
KR (1) KR100908757B1 (ru)
CN (1) CN1826407B (ru)
AU (1) AU2004249133B2 (ru)
BR (1) BRPI0410702B1 (ru)
CA (1) CA2525953C (ru)
EA (1) EA012965B1 (ru)
ES (1) ES2593082T3 (ru)
HU (1) HUE030962T2 (ru)
IL (2) IL171831A (ru)
MX (1) MX342639B (ru)
NO (1) NO341506B1 (ru)
NZ (1) NZ543446A (ru)
UA (1) UA92132C2 (ru)
WO (1) WO2004112831A2 (ru)
ZA (1) ZA200510309B (ru)

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Publication number Publication date
CA2525953A1 (en) 2004-12-29
NO341506B1 (no) 2017-11-27
US8475806B2 (en) 2013-07-02
EA012965B1 (ru) 2010-02-26
WO2004112831A2 (en) 2004-12-29
NZ543446A (en) 2008-06-30
JP2007518395A (ja) 2007-07-12
JP2013059346A (ja) 2013-04-04
EP1631663A2 (en) 2006-03-08
EP1631663B1 (en) 2016-08-24
BRPI0410702A (pt) 2006-06-13
HUE030962T2 (en) 2017-06-28
CN1826407B (zh) 2013-09-11
ZA200510309B (en) 2006-08-30
JP5215561B2 (ja) 2013-06-19
IL238584A0 (en) 2015-06-30
AU2004249133B2 (en) 2009-05-28
IL238584B (en) 2020-06-30
AU2004249133A1 (en) 2004-12-29
CN1826407A (zh) 2006-08-30
IL171831A (en) 2015-05-31
KR100908757B1 (ko) 2009-07-22
MX342639B (es) 2016-10-07
KR20060016095A (ko) 2006-02-21
BRPI0410702B1 (pt) 2022-04-12
WO2004112831A3 (en) 2005-03-24
ES2593082T3 (es) 2016-12-05
HK1082769A1 (zh) 2006-06-16
NO20056074L (no) 2006-03-22
US20050003349A1 (en) 2005-01-06
JP5695020B2 (ja) 2015-04-01
CA2525953C (en) 2023-10-10
EA200501890A1 (ru) 2006-06-30

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