UA92495C2 - Substituted oxadiazole derivatives as positive allosteric modulators of metabotropic glutamate receptors - Google Patents
Substituted oxadiazole derivatives as positive allosteric modulators of metabotropic glutamate receptorsInfo
- Publication number
- UA92495C2 UA92495C2 UAA200714065A UAA200714065A UA92495C2 UA 92495 C2 UA92495 C2 UA 92495C2 UA A200714065 A UAA200714065 A UA A200714065A UA A200714065 A UAA200714065 A UA A200714065A UA 92495 C2 UA92495 C2 UA 92495C2
- Authority
- UA
- Ukraine
- Prior art keywords
- oxadiazole derivatives
- metabotropic glutamate
- positive allosteric
- glutamate receptors
- allosteric modulators
- Prior art date
Links
- 150000004866 oxadiazoles Chemical class 0.000 title abstract 2
- 102000016193 Metabotropic glutamate receptors Human genes 0.000 title 1
- 108010010914 Metabotropic glutamate receptors Proteins 0.000 title 1
- 230000003281 allosteric effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000027232 peripheral nervous system disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
The present invention relates to new compounds which are Oxadiazole derivatives of formula (I) wherein B, P, Q, W, Rand Rare defined in the description. Invention compounds are useful in the prevention or treatment of central or peripheral nervous system disorders as well as other disorders modulated by raGluR5 receptors., (I)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0510138A GB0510138D0 (en) | 2005-05-18 | 2005-05-18 | Novel compounds A4 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA92495C2 true UA92495C2 (en) | 2010-11-10 |
Family
ID=34708376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200714065A UA92495C2 (en) | 2005-05-18 | 2006-05-17 | Substituted oxadiazole derivatives as positive allosteric modulators of metabotropic glutamate receptors |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN101228155B (en) |
| GB (1) | GB0510138D0 (en) |
| UA (1) | UA92495C2 (en) |
| ZA (1) | ZA200710278B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023122152A1 (en) * | 2021-12-22 | 2023-06-29 | Praxis Precision Medicines, Inc. | Kcnt1 inhibitors and methods of use |
-
2005
- 2005-05-18 GB GB0510138A patent/GB0510138D0/en not_active Ceased
-
2006
- 2006-05-17 UA UAA200714065A patent/UA92495C2/en unknown
- 2006-05-17 CN CN2006800252307A patent/CN101228155B/en not_active Expired - Fee Related
-
2007
- 2007-11-28 ZA ZA200710278A patent/ZA200710278B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101228155B (en) | 2012-01-11 |
| GB0510138D0 (en) | 2005-06-22 |
| CN101228155A (en) | 2008-07-23 |
| ZA200710278B (en) | 2009-12-30 |
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