[go: up one dir, main page]

UA91822C2 - 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-b] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS - Google Patents

2,3-DIHYDRO-6-NITROIMIDAZO [2,1-b] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS

Info

Publication number
UA91822C2
UA91822C2 UAA200605975A UAA200605975A UA91822C2 UA 91822 C2 UA91822 C2 UA 91822C2 UA A200605975 A UAA200605975 A UA A200605975A UA A200605975 A UAA200605975 A UA A200605975A UA 91822 C2 UA91822 C2 UA 91822C2
Authority
UA
Ukraine
Prior art keywords
group
nitroimidazo
dihydro
tuberculosis
formula
Prior art date
Application number
UAA200605975A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Хидецугу Цубоучи
Хирофуми Сасаки
Мотохиро ИТОТАНИ
Йосикадзу Харагути
Син МИЯМУРА
Макото МАЦУМОТО
Хироюки ХАСИЗУМЕ
Тацуо ТОМИСИГЕ
Масанори КАВАСАКИ
Кинуэ Огуро
Такуми Сумида
Такеси ХАСЕГАВА
Кадзуо Танака
Исао Такемура
Original Assignee
Оцука Фармасьютикел Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Оцука Фармасьютикел Ко., Лтд. filed Critical Оцука Фармасьютикел Ко., Лтд.
Publication of UA91822C2 publication Critical patent/UA91822C2/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

The present invention provides a 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound represented by the following general formula:wherein R1 represents a hydrogen atom or C1-C6 alkyl group, n represents an integer of 0 to 6, R1 and -(CH2)nR2 may form a spiro ring represented by the formula (30) below, together with the adjacent carbon atom (in the formula below, RRR represents a piperidyl group which may have substituents on the piperidine ring),and R2 represents a benzothiazolyloxy group, quinolyloxy group, pyridyloxy group or the like. The present compound has an excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria.
UAA200605975A 2003-10-31 2004-10-29 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-b] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS UA91822C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003373206 2003-10-31

Publications (1)

Publication Number Publication Date
UA91822C2 true UA91822C2 (en) 2010-09-10

Family

ID=37510729

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200605975A UA91822C2 (en) 2003-10-31 2004-10-29 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-b] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS

Country Status (3)

Country Link
CN (1) CN100497345C (en)
UA (1) UA91822C2 (en)
ZA (1) ZA200602184B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2459571B1 (en) * 2009-07-31 2015-03-11 Global Alliance For Tb Drug Development Nitroimidazooxazines and their uses in anti-tubercular therapy
TWI687409B (en) * 2014-08-28 2020-03-11 日商大塚製藥股份有限公司 Fused heterocyclic compounds
KR102485775B1 (en) * 2014-10-01 2023-01-06 헨켈 아게 운트 코. 카게아아 Cure accelerators for anaerobic curable compositions
RU2675622C1 (en) 2015-01-29 2018-12-21 Медшайн Дискавери Инк. Nitroimidazole derivative against pulmonary tuberculosis
WO2017146246A1 (en) * 2016-02-26 2017-08-31 大塚製薬株式会社 Piperidine derivative
RU2019104974A (en) * 2016-07-22 2020-08-24 Медшайн Дискавери Инк. CRYSTAL AND SALT OF NITROIMIDAZOLE AND METHOD FOR THEIR PRODUCTION
WO2019128963A1 (en) * 2017-12-26 2019-07-04 南京明德新药研发股份有限公司 Anti-pulmonary tuberculosis nitroimidazole derivative

Also Published As

Publication number Publication date
CN100497345C (en) 2009-06-10
ZA200602184B (en) 2007-10-31
CN1878777A (en) 2006-12-13

Similar Documents

Publication Publication Date Title
MY146646A (en) 2,3-dihydro-6-nitroimidazo [2,1-b] oxazole compounds for the treatment of tuberculosis
TW200420568A (en) 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound
PH12015501098A1 (en) Antituberculous composition comprising oxazole compounds
MX2009011769A (en) Pyridone derivatives as p38a mapk inhibitors.
IL186815A (en) Quinolone compound having a 3-amino-3-alkyl-4-monosubsituted or 3-amino-3- alkyl-4, 4-disubstituted pyrroliidinyl substituent
TW200503621A (en) Pyrimidine compound and pests controlling composition containing the same
MX2009010814A (en) Hydrazide compound and harmful arthropod-controlling agent containing the same.
BG108174A (en) 5-phenylpyrimidines, methods and intermediate products for the production thereof and use of the same for controlling pathogenic fungi
MX2009010846A (en) Process for producing pesticidal benzamide compounds.
MX2009010823A (en) Hydrazide compound and harmful arthropod-controlling agent containing the same.
UA91822C2 (en) 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-b] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS
MY140749A (en) Novel piperidine compound
TNSN07357A1 (en) Indanyl-piperazine derivatives, method for preparing same and pharmaceutical compositions containing same
MX2023009666A (en) Herbicidal composition.
TW200600085A (en) External preparation
TW200609220A (en) Tetrahydroisoquinolylsulphonamide derivatives, their preparation and their use in therapeutics
MX2009011888A (en) Epoxy compound and method for manufacturing the same.
DK0841327T3 (en) Triazolant antifungal agent
EP0995744A4 (en) Cis-substituted fluoromethylpyrrolidine derivatives
MX2009004928A (en) Method for producing 2-alkyl-3-aminothiophene derivative.
GB0428137D0 (en) Novel herbicides
BR9812928A (en) New 3-oxo- (2h) -1,2,4-triazine derivatives, process for preparing chemical compounds, and pharmaceutical composition
TW200716604A (en) Carboxamide compound and use thereof
TW200517446A (en) Poly-azo compound, and polarization film having said compound
TW200609232A (en) 1,4-dithienylbenzene derivatives