UA89037C2 - Способ получения кислотно-аддитивной соли венлафаксина - Google Patents
Способ получения кислотно-аддитивной соли венлафаксинаInfo
- Publication number
- UA89037C2 UA89037C2 UAA200607938A UAA200607938A UA89037C2 UA 89037 C2 UA89037 C2 UA 89037C2 UA A200607938 A UAA200607938 A UA A200607938A UA A200607938 A UAA200607938 A UA A200607938A UA 89037 C2 UA89037 C2 UA 89037C2
- Authority
- UA
- Ukraine
- Prior art keywords
- acid addition
- addition salt
- preparing venlafaxine
- preparing
- venlafaxine
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- PNVNVHUZROJLTJ-UHFFFAOYSA-N venlafaxine Chemical compound C1=CC(OC)=CC=C1C(CN(C)C)C1(O)CCCCC1 PNVNVHUZROJLTJ-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004688 venlafaxine Drugs 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10359154A DE10359154A1 (de) | 2003-12-16 | 2003-12-16 | Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA89037C2 true UA89037C2 (ru) | 2009-12-25 |
Family
ID=34683449
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200904707A UA91153C2 (ru) | 2003-12-16 | 2004-12-10 | Способ получения формы и венлафаксина гидрохлорида |
| UAA200904706A UA90630C2 (ru) | 2003-12-16 | 2004-12-10 | Способ получения формы и венлафаксина гидрохлорида |
| UAA200607938A UA89037C2 (ru) | 2003-12-16 | 2004-12-10 | Способ получения кислотно-аддитивной соли венлафаксина |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200904707A UA91153C2 (ru) | 2003-12-16 | 2004-12-10 | Способ получения формы и венлафаксина гидрохлорида |
| UAA200904706A UA90630C2 (ru) | 2003-12-16 | 2004-12-10 | Способ получения формы и венлафаксина гидрохлорида |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7745664B2 (ru) |
| EP (2) | EP2181982B1 (ru) |
| DE (1) | DE10359154A1 (ru) |
| EA (1) | EA011763B1 (ru) |
| PL (1) | PL2181982T3 (ru) |
| SI (1) | SI2181982T1 (ru) |
| UA (3) | UA91153C2 (ru) |
| WO (1) | WO2005058796A2 (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10359154A1 (de) | 2003-12-16 | 2005-07-28 | Krka Tovarna Zdravil, D.D. | Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I |
| JP2009511641A (ja) * | 2005-10-19 | 2009-03-19 | テバ ファーマシューティカル インダストリーズ リミティド | 高純度1−〔2−ジメチルアミノ−(4−メトキシフェニル)エチル〕シクロヘキサノール塩酸塩の調製方法 |
| PL2125698T3 (pl) | 2007-03-15 | 2017-03-31 | Auspex Pharmaceuticals, Inc. | Deuterowana wenlafaksyna-d9 |
| CN101279926A (zh) * | 2008-05-22 | 2008-10-08 | 杭州盛美医药科技开发有限公司 | 盐酸文拉法辛晶型FormⅠ的制备方法 |
| US8754261B2 (en) | 2009-12-16 | 2014-06-17 | Pharmathen S.A. | Process for the preparation of O-desmethyl-venlafaxine and salts thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE56324B1 (en) | 1982-12-13 | 1991-06-19 | American Home Prod | Phenethylamine derivatives and intermediates therefor |
| PE57198A1 (es) | 1996-03-25 | 1998-10-10 | American Home Prod | Formula de liberacion prolongada |
| US20020183553A1 (en) * | 2000-10-19 | 2002-12-05 | Ben-Zion Dolitzky | Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof |
| PL365895A1 (en) * | 2000-10-19 | 2005-01-10 | Teva Pharmaceutical Industries Ltd. | Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochloride, processes for preparing thereof |
| WO2002050017A1 (en) | 2000-12-20 | 2002-06-27 | Ciba Specialty Chemicals Holding Inc. | Process for the preparation of phenethylamine derivatives |
| WO2003050074A1 (en) | 2001-12-13 | 2003-06-19 | Cadila Healthcare Limited | Manufacture of venlafaxine hydrochloride and crystalline polymorphs thereof |
| DE60229789D1 (de) * | 2002-03-26 | 2008-12-18 | Nicholas Piramal India Ltd | Verfahren zur herstellung von phenylethylaminen, insbesondere venlafaxin |
| DE10359154A1 (de) | 2003-12-16 | 2005-07-28 | Krka Tovarna Zdravil, D.D. | Verfahren zur Herstellung von Venlafaxin und Venlafaxinhydrochlorid der Form I |
-
2003
- 2003-12-16 DE DE10359154A patent/DE10359154A1/de not_active Withdrawn
-
2004
- 2004-12-10 EP EP10000777.2A patent/EP2181982B1/en not_active Expired - Lifetime
- 2004-12-10 WO PCT/EP2004/014102 patent/WO2005058796A2/en not_active Ceased
- 2004-12-10 PL PL10000777T patent/PL2181982T3/pl unknown
- 2004-12-10 UA UAA200904707A patent/UA91153C2/ru unknown
- 2004-12-10 UA UAA200904706A patent/UA90630C2/ru unknown
- 2004-12-10 US US10/583,439 patent/US7745664B2/en not_active Expired - Fee Related
- 2004-12-10 UA UAA200607938A patent/UA89037C2/ru unknown
- 2004-12-10 EP EP04803746A patent/EP1697299A2/en not_active Withdrawn
- 2004-12-10 SI SI200432072T patent/SI2181982T1/sl unknown
- 2004-12-10 EA EA200600977A patent/EA011763B1/ru not_active IP Right Cessation
-
2009
- 2009-06-04 US US12/478,375 patent/US7728173B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EA011763B1 (ru) | 2009-06-30 |
| US20070185354A1 (en) | 2007-08-09 |
| PL2181982T3 (pl) | 2013-12-31 |
| WO2005058796A3 (en) | 2005-10-06 |
| SI2181982T1 (sl) | 2013-10-30 |
| DE10359154A1 (de) | 2005-07-28 |
| EP2181982B1 (en) | 2013-07-31 |
| EP1697299A2 (en) | 2006-09-06 |
| US7745664B2 (en) | 2010-06-29 |
| EP2181982A1 (en) | 2010-05-05 |
| US20090240082A1 (en) | 2009-09-24 |
| UA90630C2 (ru) | 2010-05-11 |
| EA200600977A1 (ru) | 2006-10-27 |
| WO2005058796A2 (en) | 2005-06-30 |
| US7728173B2 (en) | 2010-06-01 |
| UA91153C2 (ru) | 2010-06-25 |
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