UA89614C2 - Process for the production of the rosuvastatin calcium salt - Google Patents
Process for the production of the rosuvastatin calcium saltInfo
- Publication number
- UA89614C2 UA89614C2 UAA200511187A UAA200511187A UA89614C2 UA 89614 C2 UA89614 C2 UA 89614C2 UA A200511187 A UAA200511187 A UA A200511187A UA A200511187 A UAA200511187 A UA A200511187A UA 89614 C2 UA89614 C2 UA 89614C2
- Authority
- UA
- Ukraine
- Prior art keywords
- production
- calcium salt
- rosuvastatin calcium
- useful
- dihydroxyhept
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- LALFOYNTGMUKGG-BGRFNVSISA-L rosuvastatin calcium Chemical class [Ca+2].CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O.CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O LALFOYNTGMUKGG-BGRFNVSISA-L 0.000 title 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 1
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 208000020346 hyperlipoproteinemia Diseases 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000004528 pyrimidin-5-yl group Chemical group N1=CN=CC(=C1)* 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
An improved process for manufacture of (E-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3N,5S)-3,5-dihydroxyhept-6-enoic acid calcium salt, Formula (1), which is useful for the production of a pharmaceutical useful in the treatment of, inter alia, hypercholesterolemia, hyperlipoproteinemia and atherosclerosis, is described.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0312896.4A GB0312896D0 (en) | 2003-06-05 | 2003-06-05 | Chemical process |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA89614C2 true UA89614C2 (en) | 2010-02-25 |
Family
ID=40651873
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200511187A UA89614C2 (en) | 2003-06-05 | 2004-06-03 | Process for the production of the rosuvastatin calcium salt |
Country Status (2)
| Country | Link |
|---|---|
| UA (1) | UA89614C2 (en) |
| ZA (1) | ZA200509539B (en) |
-
2004
- 2004-06-03 UA UAA200511187A patent/UA89614C2/en unknown
-
2005
- 2005-11-24 ZA ZA200509539A patent/ZA200509539B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200509539B (en) | 2007-09-26 |
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