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UA89481C2 - Эритропоэтиновые миметические шарнирно-сердцевинные миметитела человека, композиции, способы и применение - Google Patents

Эритропоэтиновые миметические шарнирно-сердцевинные миметитела человека, композиции, способы и применение Download PDF

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Publication number
UA89481C2
UA89481C2 UAA200604029A UAA200604029A UA89481C2 UA 89481 C2 UA89481 C2 UA 89481C2 UA A200604029 A UAA200604029 A UA A200604029A UA A200604029 A UAA200604029 A UA A200604029A UA 89481 C2 UA89481 C2 UA 89481C2
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UA
Ukraine
Prior art keywords
mimetic
hydrochloride
epo mimetic
mimetyl
variant
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UAA200604029A
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English (en)
Ukrainian (uk)
Inventor
Джордж Хевнер
Дэвид М. Найт
Бернард Скеллон
Джон Грейб
Томас С. Несспор
Чичи Хуанг
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Центокор, Инк.
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Publication of UA89481C2 publication Critical patent/UA89481C2/ru

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07ORGANIC CHEMISTRY
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    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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Abstract

Данное изобретение относится к новому ЭПО миметическому шарнирно-сердцевинному миметителу человека, а также изолированной нуклеиновой кислоты, которая кодирует ЭПО миметическое шарнирно-сердцевинное миметитело, вектора, клетки-хозяина, применению терапевтической композиции для лечения болезненного состояния, связанного с ЭПО лигандом у человека.
UAA200604029A 2003-09-30 2004-03-09 Эритропоэтиновые миметические шарнирно-сердцевинные миметитела человека, композиции, способы и применение UA89481C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50734903P 2003-09-30 2003-09-30

Publications (1)

Publication Number Publication Date
UA89481C2 true UA89481C2 (ru) 2010-02-10

Family

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UAA200604029A UA89481C2 (ru) 2003-09-30 2004-03-09 Эритропоэтиновые миметические шарнирно-сердцевинные миметитела человека, композиции, способы и применение

Country Status (28)

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EP (2) EP1675579B1 (ru)
JP (1) JP4810428B2 (ru)
KR (1) KR101201339B1 (ru)
CN (1) CN1894275B (ru)
AR (1) AR046415A1 (ru)
AT (1) ATE439370T1 (ru)
AU (1) AU2004277884B2 (ru)
BR (1) BRPI0414893A (ru)
CA (1) CA2540665A1 (ru)
CO (1) CO5690612A2 (ru)
CR (1) CR8320A (ru)
CY (1) CY1109579T1 (ru)
DE (1) DE602004022571D1 (ru)
DK (1) DK1675579T3 (ru)
EA (1) EA009377B1 (ru)
EC (1) ECSP066466A (ru)
ES (1) ES2329799T3 (ru)
IL (2) IL174676A (ru)
NO (1) NO20061931L (ru)
NZ (1) NZ546287A (ru)
PL (1) PL1675579T3 (ru)
PT (1) PT1675579E (ru)
SG (1) SG149074A1 (ru)
SI (1) SI1675579T1 (ru)
TW (1) TWI344987B (ru)
UA (1) UA89481C2 (ru)
WO (1) WO2005032460A2 (ru)
ZA (1) ZA200603425B (ru)

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