UA89408C2 - Sustained release solid pharmaceutical composition of 1-(2,3,4-trimethoxybenzyl)piperazine and a method for the preparation thereof - Google Patents
Sustained release solid pharmaceutical composition of 1-(2,3,4-trimethoxybenzyl)piperazine and a method for the preparation thereofInfo
- Publication number
- UA89408C2 UA89408C2 UAA200714180A UAA200714180A UA89408C2 UA 89408 C2 UA89408 C2 UA 89408C2 UA A200714180 A UAA200714180 A UA A200714180A UA A200714180 A UAA200714180 A UA A200714180A UA 89408 C2 UA89408 C2 UA 89408C2
- Authority
- UA
- Ukraine
- Prior art keywords
- trimethoxybenzyl
- pharmaceutical composition
- sustained release
- piperazine
- solid pharmaceutical
- Prior art date
Links
- UHWVSEOVJBQKBE-UHFFFAOYSA-N Trimetazidine Chemical group COC1=C(OC)C(OC)=CC=C1CN1CCNCC1 UHWVSEOVJBQKBE-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 238000013268 sustained release Methods 0.000 title abstract 2
- 239000012730 sustained-release form Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The inventive sustained release solid pharmaceutical composition comprises an 1-(2,3,4-trimethoxybenzyl) piperazine active substance or the pharmaceutically acceptable salt thereof combined with at least one type of polyethylene oxide, at least one type of lubricating agent and one or several pharmaceutically acceptable excipients.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0504997A FR2885807B1 (en) | 2005-05-18 | 2005-05-18 | SOLID PHARMACEUTICAL COMPOSITION WITH PROLONGED RELEASE OF 1- (2,3,4-TRIMETHOXYBENZYL) PIPERAZINE, AND PREPARATION METHOD |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA89408C2 true UA89408C2 (en) | 2010-01-25 |
Family
ID=35583424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200714180A UA89408C2 (en) | 2005-05-18 | 2006-02-13 | Sustained release solid pharmaceutical composition of 1-(2,3,4-trimethoxybenzyl)piperazine and a method for the preparation thereof |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1881831A1 (en) |
| EA (1) | EA013645B1 (en) |
| FR (1) | FR2885807B1 (en) |
| UA (1) | UA89408C2 (en) |
| WO (1) | WO2006123073A1 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0815602A2 (en) * | 2007-08-08 | 2015-03-03 | Usv Ltd | PROPOSED TRIMETHYZIDINE RELEASE COMPOSITIONS AND PROCESS FOR PREPARING THEM |
| EP2200591A2 (en) * | 2007-09-11 | 2010-06-30 | Ranbaxy Laboratories Limited | Controlled release pharmaceutical dosage forms of trimetazidine |
| US20110300209A1 (en) * | 2009-01-20 | 2011-12-08 | Micro Labs Limited | Modified release solid pharmaceutical compositions of trimetazidine and process thereof |
| TR201001902A2 (en) * | 2010-03-12 | 2011-04-21 | Ali̇ Rai̇f İlaç Sanayi̇ Ve Ti̇caret A.Ş. | Trimetazidine tablets with extended release |
| PL2394644T3 (en) * | 2010-05-04 | 2014-11-28 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | Trimetazidine Formulation With Different Release Profiles |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2717687B1 (en) * | 1994-03-24 | 1996-06-14 | Adir | Pharmaceutical compositions for the sustained release of trimetazidine after oral administration. |
| FR2802424B1 (en) * | 1999-12-17 | 2002-02-15 | Adir | MATRIX TABLET FOR THE EXTENDED RELEASE OF TRIMETAZIDINE AFTER ORAL ADMINISTRATION |
| PT1195160E (en) * | 2000-10-05 | 2009-12-07 | Usv Ltd | Sustained release trimetazidine pharmaceutical compositions and a method of their preparation |
| FR2818549B1 (en) * | 2000-12-26 | 2003-02-07 | Servier Lab | SOLID THERMOFORMABLE PHARMACEUTICAL COMPOSITION FOR THE CONTROLLED RELEASE OF TRIMETAZIDINE |
| AU2002356425A1 (en) * | 2001-11-21 | 2003-06-10 | Themis Laboratories Private Limited | A process for manufacture of a sustained release composition containing microbe |
-
2005
- 2005-05-18 FR FR0504997A patent/FR2885807B1/en not_active Expired - Lifetime
-
2006
- 2006-02-13 UA UAA200714180A patent/UA89408C2/en unknown
- 2006-02-13 WO PCT/FR2006/050128 patent/WO2006123073A1/en not_active Ceased
- 2006-02-13 EA EA200702386A patent/EA013645B1/en not_active IP Right Cessation
- 2006-02-13 EP EP06709507A patent/EP1881831A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| FR2885807B1 (en) | 2008-05-16 |
| EA013645B1 (en) | 2010-06-30 |
| FR2885807A1 (en) | 2006-11-24 |
| WO2006123073A1 (en) | 2006-11-23 |
| EP1881831A1 (en) | 2008-01-30 |
| EA200702386A1 (en) | 2008-04-28 |
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