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UA87453C2 - Применения фрагмента ав для лечения болезни альцгеймера - Google Patents

Применения фрагмента ав для лечения болезни альцгеймера

Info

Publication number
UA87453C2
UA87453C2 UAA200507593A UA2005007593A UA87453C2 UA 87453 C2 UA87453 C2 UA 87453C2 UA A200507593 A UAA200507593 A UA A200507593A UA 2005007593 A UA2005007593 A UA 2005007593A UA 87453 C2 UA87453 C2 UA 87453C2
Authority
UA
Ukraine
Prior art keywords
beta
disease
antibodies
alzheimer
fragment
Prior art date
Application number
UAA200507593A
Other languages
English (en)
Ukrainian (uk)
Inventor
Фредерик Бард
Тед Эднок
Ники Васквез
Питер А. Сьюберт
Original Assignee
Вайет
Елан Фарма Интернешенл Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32850829&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA87453(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Вайет, Елан Фарма Интернешенл Лимитед filed Critical Вайет
Publication of UA87453C2 publication Critical patent/UA87453C2/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение касается применения фрагмента Аβ, который состоит из Аβ16-23 и имеет аминокислотную последовательность KLVFFAED, или его коньюгата с молекулой-носителем, где молекула-носитель помогает вызывать иммунную реакцию на фрагмент, в производстве лекарственного средства для эффективного лечения или профилактики болезни Альцгеймера у пациента.
UAA200507593A 2003-02-01 2004-01-31 Применения фрагмента ав для лечения болезни альцгеймера UA87453C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44415003P 2003-02-01 2003-02-01

Publications (1)

Publication Number Publication Date
UA87453C2 true UA87453C2 (ru) 2009-07-27

Family

ID=32850829

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200507593A UA87453C2 (ru) 2003-02-01 2004-01-31 Применения фрагмента ав для лечения болезни альцгеймера

Country Status (20)

Country Link
US (3) US20060188512A1 (ru)
EP (1) EP1594969B1 (ru)
JP (1) JP2006516639A (ru)
KR (1) KR20050118669A (ru)
CN (1) CN1745175A (ru)
AU (1) AU2004209981B2 (ru)
BR (1) BRPI0407058A (ru)
CA (1) CA2513722A1 (ru)
CR (1) CR7922A (ru)
EC (1) ECSP055939A (ru)
ES (1) ES2545765T3 (ru)
HR (1) HRP20050670A2 (ru)
MX (1) MXPA05008156A (ru)
NO (1) NO20053862L (ru)
NZ (1) NZ567324A (ru)
PL (1) PL378571A1 (ru)
RU (1) RU2390350C2 (ru)
UA (1) UA87453C2 (ru)
WO (1) WO2004069182A2 (ru)
ZA (1) ZA200505782B (ru)

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