UA86077C2 - Cetp inhibitors - Google Patents
Cetp inhibitorsInfo
- Publication number
- UA86077C2 UA86077C2 UAA200701058A UAA200701058A UA86077C2 UA 86077 C2 UA86077 C2 UA 86077C2 UA A200701058 A UAA200701058 A UA A200701058A UA A200701058 A UAA200701058 A UA A200701058A UA 86077 C2 UA86077 C2 UA 86077C2
- Authority
- UA
- Ukraine
- Prior art keywords
- compounds
- ring
- cetp inhibitors
- benzoheterocyclic
- formula
- Prior art date
Links
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 238000008214 LDL Cholesterol Methods 0.000 abstract 1
- 108010028554 LDL Cholesterol Proteins 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-choleslerol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula 1 В or Ris a phenyl group which has an ortho aryl, heterocyclic, benzoheterocyclic or benzocycloalkyl substituent, and one other position on the 5 membered ring has an aromalic, helerocyclic, cycloalkyl, benzoheterocyclic or benzocycloalkyl substituent connected directly to the ring or attached to the ring through a -CH-.І
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58527404P | 2004-07-02 | 2004-07-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA86077C2 true UA86077C2 (en) | 2009-03-25 |
Family
ID=38131543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200701058A UA86077C2 (en) | 2004-07-02 | 2005-07-01 | Cetp inhibitors |
Country Status (5)
| Country | Link |
|---|---|
| CN (1) | CN1980904A (en) |
| HN (1) | HN2005000340A (en) |
| TN (1) | TNSN06456A1 (en) |
| UA (1) | UA86077C2 (en) |
| ZA (1) | ZA200610565B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2985022B1 (en) * | 2005-07-01 | 2018-09-12 | Merck Sharp & Dohme Corp. | Process for synthesizing a cetp inhibitor |
| CN101412711A (en) * | 2007-10-15 | 2009-04-22 | 上海恒瑞医药有限公司 | Carbamate derivatives and use thereof in medicine |
| JP5852662B2 (en) * | 2010-10-29 | 2016-02-03 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | Cyclic amine substituted oxazolidinone CETP inhibitors |
| US9724336B2 (en) * | 2011-11-30 | 2017-08-08 | Daewoong Pharmaceutical Co., Ltd. | Pharmaceutical composition for preventing or treating hyperlipidemia |
| CN102516237B (en) * | 2011-12-05 | 2014-02-26 | 成都苑东药业有限公司 | Oxazolidinone derivative |
| CN102603499A (en) * | 2012-03-01 | 2012-07-25 | 南京药石药物研发有限公司 | Synthetic method of 1-bromo-4-fluorin-5-isopropyl-2-metoxybenzene |
| CN116078377B (en) * | 2023-03-06 | 2023-06-27 | 泽升科技(广州)有限公司 | Production process for preparing deuterated benzene by using supported catalyst |
-
2005
- 2005-06-29 HN HN2005000340A patent/HN2005000340A/en unknown
- 2005-07-01 CN CNA2005800226187A patent/CN1980904A/en active Pending
- 2005-07-01 UA UAA200701058A patent/UA86077C2/en unknown
-
2006
- 2006-12-15 ZA ZA200610565A patent/ZA200610565B/en unknown
- 2006-12-29 TN TNP2006000456A patent/TNSN06456A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN06456A1 (en) | 2008-02-22 |
| HN2005000340A (en) | 2009-11-06 |
| CN1980904A (en) | 2007-06-13 |
| ZA200610565B (en) | 2008-07-30 |
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