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UA85994C2 - N, n'-substituted-1,3-diamino-2-hydroxypropane derivatives - Google Patents

N, n'-substituted-1,3-diamino-2-hydroxypropane derivatives

Info

Publication number
UA85994C2
UA85994C2 UA20040604411A UA20040604411A UA85994C2 UA 85994 C2 UA85994 C2 UA 85994C2 UA 20040604411 A UA20040604411 A UA 20040604411A UA 20040604411 A UA20040604411 A UA 20040604411A UA 85994 C2 UA85994 C2 UA 85994C2
Authority
UA
Ukraine
Prior art keywords
diamino
substituted
hydroxypropane derivatives
hydroxypropane
derivatives
Prior art date
Application number
UA20040604411A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Варгес Джон
Мишель Мейлард
Барбара Ягодзинская
Джеймс П. Бек
Андреа Гейлунас
Ларри Фенг
Дженнифер СИЛИ
Рут Тенбринк
Джон Фрескос
Джон Микельсон
Лаксман Самала
Рой Хом
Original Assignee
Элан Фармасьютикалз, Инк.
Фармациа Энд Апджон Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Элан Фармасьютикалз, Инк., Фармациа Энд Апджон Компани filed Critical Элан Фармасьютикалз, Инк.
Publication of UA85994C2 publication Critical patent/UA85994C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Disclosed are compounds of the formula (I), wherein the variables R, R, R, R, R, and Rare as defined herein. These compounds have activity as inhibitors of betasecretase and are therefore useful in treating a variety of discorders such as Alzheimer's Disease.(І)
UA20040604411A 2001-11-08 2002-11-08 N, n'-substituted-1,3-diamino-2-hydroxypropane derivatives UA85994C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33712201P 2001-11-08 2001-11-08

Publications (1)

Publication Number Publication Date
UA85994C2 true UA85994C2 (en) 2009-03-25

Family

ID=35976924

Family Applications (1)

Application Number Title Priority Date Filing Date
UA20040604411A UA85994C2 (en) 2001-11-08 2002-11-08 N, n'-substituted-1,3-diamino-2-hydroxypropane derivatives

Country Status (3)

Country Link
CN (1) CN1759095A (en)
UA (1) UA85994C2 (en)
ZA (1) ZA200403578B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102344402B (en) * 2010-07-30 2015-01-07 中国人民解放军军事医学科学院毒物药物研究所 Benzoazacyclo hydroxyethylamine compounds, preparation method thereof and purposes thereof
TWI507381B (en) * 2010-09-08 2015-11-11 Sumitomo Chemical Co Method for producing pyridazinone compounds and intermediate thereof
CN110407763B (en) * 2019-08-08 2022-10-14 苏州汉德创宏生化科技有限公司 Synthesis method of 4- (oxazole-2-yl) benzoic acid
CA3177962A1 (en) * 2020-07-31 2022-02-03 Yongmei Xie Multi-efficacy pyrazine compound, preparation method and use thereof

Also Published As

Publication number Publication date
ZA200403578B (en) 2005-10-10
CN1759095A (en) 2006-04-12

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