UA106818C2 - Method for manufacturing desmopressin acetate tablets - Google Patents
Method for manufacturing desmopressin acetate tabletsInfo
- Publication number
- UA106818C2 UA106818C2 UAA201302250A UAA201302250A UA106818C2 UA 106818 C2 UA106818 C2 UA 106818C2 UA A201302250 A UAA201302250 A UA A201302250A UA A201302250 A UAA201302250 A UA A201302250A UA 106818 C2 UA106818 C2 UA 106818C2
- Authority
- UA
- Ukraine
- Prior art keywords
- desmopressin acetate
- manufacturing
- desmopressin
- copovidon
- excipients
- Prior art date
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
The invention relates to the method for manufacturing Desmopressin acetate tablets comprising the dissolution of the active ingredient, the addition of the excipients, the granulation and tabletting. Copovidon is selected as a substance that regulates the rate of Desmopressin release. Desmopressin acetate is added to Copovidon solution, the mixture is stirred until the complete dissolution. The solution is used for moistening the mixture of the excipients – starch and lactose followed by wet granulation. The wet granules are dried at the temperature of 45-50 ºC until the residual moisture content not more than 5 %, granulated through the sieve, 1 mm mesh size, powdered with magnesium stearate and compressed. The invention relates to pharmaceutical composition and method for its manufacture and use in the treatment and prevention of the primary nocturnal enuresis, nicturia and other diseases including central diabetes insipidus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAA201302250A UA106818C2 (en) | 2013-02-22 | 2013-02-22 | Method for manufacturing desmopressin acetate tablets |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| UAA201302250A UA106818C2 (en) | 2013-02-22 | 2013-02-22 | Method for manufacturing desmopressin acetate tablets |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA106818C2 true UA106818C2 (en) | 2014-10-10 |
Family
ID=56277331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201302250A UA106818C2 (en) | 2013-02-22 | 2013-02-22 | Method for manufacturing desmopressin acetate tablets |
Country Status (1)
| Country | Link |
|---|---|
| UA (1) | UA106818C2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106727379A (en) * | 2016-12-28 | 2017-05-31 | 江苏飞马药业有限公司 | A kind of desmopressin acetate tablet composition and preparation method thereof |
-
2013
- 2013-02-22 UA UAA201302250A patent/UA106818C2/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106727379A (en) * | 2016-12-28 | 2017-05-31 | 江苏飞马药业有限公司 | A kind of desmopressin acetate tablet composition and preparation method thereof |
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