UA106222C2 - Poly (adp-ribose) polymerase (parp) inhibitors - Google Patents
Poly (adp-ribose) polymerase (parp) inhibitorsInfo
- Publication number
- UA106222C2 UA106222C2 UAA201110274A UAA201110274A UA106222C2 UA 106222 C2 UA106222 C2 UA 106222C2 UA A201110274 A UAA201110274 A UA A201110274A UA A201110274 A UAA201110274 A UA A201110274A UA 106222 C2 UA106222 C2 UA 106222C2
- Authority
- UA
- Ukraine
- Prior art keywords
- compounds
- parp
- adp
- ribose
- polymerase
- Prior art date
Links
- 229920000776 Poly(Adenosine diphosphate-ribose) polymerase Polymers 0.000 title abstract 2
- 102000012338 Poly(ADP-ribose) Polymerases Human genes 0.000 title 1
- 108010061844 Poly(ADP-ribose) Polymerases Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 101710179684 Poly [ADP-ribose] polymerase Proteins 0.000 abstract 1
- 102100023712 Poly [ADP-ribose] polymerase 1 Human genes 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Disclosed are compounds of the following formula: (I) in which R, R, R, R, R, R, R, X, and t are defined in the specification. Also disclosed are pharmaceutical compositions, kits, and articles of manufacture, which contain the compounds, methods and intermediates useful for making the compounds, and methods of using the compounds to treat diseases, disorders, and conditions related to PARP activity.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14674009P | 2009-01-23 | 2009-01-23 | |
| PCT/US2010/021669 WO2010085570A1 (en) | 2009-01-23 | 2010-01-21 | Poly (ADP-Ribose) Polymerase (PARP) Inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA106222C2 true UA106222C2 (en) | 2014-08-11 |
Family
ID=52682157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201110274A UA106222C2 (en) | 2009-01-23 | 2010-01-21 | Poly (adp-ribose) polymerase (parp) inhibitors |
Country Status (1)
| Country | Link |
|---|---|
| UA (1) | UA106222C2 (en) |
-
2010
- 2010-01-21 UA UAA201110274A patent/UA106222C2/en unknown
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