TWM632571U - Lozenges with long-lasting absorption function structure - Google Patents
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- 238000010521 absorption reaction Methods 0.000 title claims abstract description 109
- 239000007937 lozenge Substances 0.000 title claims abstract description 91
- 230000005923 long-lasting effect Effects 0.000 title claims abstract description 71
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims abstract description 49
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 34
- 239000004615 ingredient Substances 0.000 claims abstract description 33
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- 108010035532 Collagen Proteins 0.000 claims abstract description 17
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 17
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- 239000000546 pharmaceutical excipient Substances 0.000 claims description 23
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- 238000004806 packaging method and process Methods 0.000 claims description 16
- 239000004743 Polypropylene Substances 0.000 claims description 8
- 229920001155 polypropylene Polymers 0.000 claims description 8
- -1 polypropylene Polymers 0.000 claims description 6
- 230000004308 accommodation Effects 0.000 claims description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 3
- 229910052782 aluminium Inorganic materials 0.000 claims description 3
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- 239000000463 material Substances 0.000 claims description 3
- 239000003814 drug Substances 0.000 abstract description 16
- 229940079593 drug Drugs 0.000 abstract description 15
- 238000013268 sustained release Methods 0.000 abstract description 11
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Abstract
本創作係關於具長效吸收機能結構的錠劑,包括長效核心及速釋外層,其中速釋外層係包圍長效核心,並至少具有潰散成分。另一實施例中,速釋外層鄰設於長效核心,並且彼此貼合。另一實施例中,長效核心或是速釋外層上具有粗糙面,以調整緩釋的時間及崩解的時間。另一實施例中,長效核心及速釋外層係針對人體消化系統,分別包括不同比例的膠原蛋白粉末及維生素C,設計出可提升人體消化系統吸收率的特殊結構,讓人體能夠有效吸收膠原蛋白及維生素C等效性成分,可調整吸收及釋放的時間,並避免未吸收的藥物殘留在體內,以降低人體的負擔。 The invention relates to a lozenge with a long-acting absorption structure, including a long-acting core and an immediate-release outer layer, wherein the immediate-release outer layer surrounds the long-acting core and has at least a collapsible component. In another embodiment, the immediate release outer layer is adjacent to the long-lasting core and adheres to each other. In another embodiment, the long-acting core or the quick-release outer layer has a rough surface to adjust the time of sustained release and disintegration. In another embodiment, the long-acting core and the quick-release outer layer are aimed at the human digestive system, respectively including different proportions of collagen powder and vitamin C, and are designed with a special structure that can improve the absorption rate of the human digestive system, so that the human body can effectively absorb collagen Protein and vitamin C equivalent ingredients can adjust the time of absorption and release, and avoid unabsorbed drugs remaining in the body to reduce the burden on the human body.
Description
本創作是有關於一種具長效吸收機能結構的錠劑,依據消化系統的特性來進行設計,將有效成分以不同比例壓製成長效核心及速釋外層,並配合不同設計的結構,調整吸收及釋放的時間,以增加身體吸收率。 This creation is about a lozenge with a long-acting absorption structure. It is designed according to the characteristics of the digestive system. The active ingredients are compressed into the long-acting core and the quick-release outer layer in different proportions, and the structure of different designs is used to adjust the absorption and absorption. Release time to increase body absorption rate.
考慮到藥物本身的物理化學性,以及必須滿足服藥的方便性,便發展出許多不同口服劑型,例如:錠劑、膠囊、口服液等等。其中,直接製成錠劑是最常見的,製作過程相對容易,是將賦型劑與效性成分直接加壓成錠劑,再直接以口服的方式服用即可。一般常見的有錠劑、可咀嚼錠、膜衣錠、口溶錠、舌下錠及膠囊。 Considering the physical and chemical properties of the drug itself and the need to meet the convenience of taking the drug, many different oral dosage forms have been developed, such as: lozenges, capsules, oral liquids, etc. Among them, directly making lozenges is the most common, and the production process is relatively easy. The excipients and active ingredients are directly compressed into lozenges, and then directly taken orally. Generally, there are lozenges, chewable tablets, film-coated tablets, oral dissolving tablets, sublingual tablets and capsules.
錠劑進入人體後,係被人體器官分解,再經由消化來吸收養份,使有效成分達到其功效。人體主要負責吸收養份的器官是腸道,而胃部則係負責分解食物,一般消化系統的運作流程是先待胃部將食物完成分解後,再到腸道進行養份吸收;由於人體的消化系統具有此特點,現今已有前案針對藥物進入人體後的吸收效果進行改良,使得藥物主要的效性成分在胃部時可獲得保護,直到進入腸道後才被吸收,然而,如何最佳化藥物的被吸收率,卻始終是需要突破的課題。 After the lozenge enters the human body, it is decomposed by human organs, and then absorbed nutrients through digestion, so that the active ingredients can achieve their effects. The main organ of the human body responsible for absorbing nutrients is the intestinal tract, while the stomach is responsible for decomposing food. Generally, the operation process of the digestive system is to wait for the stomach to complete the decomposition of food, and then go to the intestinal tract for nutrient absorption; due to the human body’s The digestive system has this characteristic, and there have been previous cases to improve the absorption effect of the drug after entering the human body, so that the main active ingredients of the drug can be protected when they enter the stomach, and are not absorbed until they enter the intestinal tract. However, how to best However, the absorption rate of chemical drugs is always a subject that needs to be broken through.
目前市售醫藥物的有效成分之釋放時間過短,效性成分的吸收率過低,因此,不得不提升食用頻率,而在提升食用頻率的同時, 賦型劑的量也就相對提高,如此,血液中賦型劑的濃度太高,對身體造成負擔,並增加副作用可能產生的危險性。此外,有效成分在短時間內全部釋放,在胃部環境內會被胃酸破壞,且多數無法被胃部吸收,在進入腸道後,又因效性成分早已被胃酸破壞而無法被腸道吸收,所以,目前市售醫藥物及健康食品中效性成分的吸收率仍有所不足。 The release time of the active ingredients of currently commercially available medicines is too short, and the absorption rate of the active ingredients is too low. Therefore, the frequency of consumption has to be increased, and while increasing the frequency of consumption, The amount of the excipient is also relatively increased, so that the concentration of the excipient in the blood is too high, which will burden the body and increase the risk of possible side effects. In addition, all active ingredients are released in a short period of time, and will be destroyed by gastric acid in the stomach environment, and most of them cannot be absorbed by the stomach. After entering the intestinal tract, the active ingredients have already been destroyed by gastric acid and cannot be absorbed by the intestinal tract. Therefore, the absorption rate of effective ingredients in currently marketed medicines and health foods is still insufficient.
胃部及腸道對於不同的效性成分係具有不同的吸收效果,因此,雖然目前有許多前案已針對人體消化系統的特點做研究,並對藥物進入人體後的吸收效果進行改良,但是仍須配合胃部及腸道對於不同效性成分所具有不同的吸收效果做進一步的探討,方能找到最佳的藥物被吸收率;特別是,藥物的被吸收率越高,除了藥物的效能越好之外,還可降低人體的負擔,避免未被吸收的藥物仍殘留在體內。 The stomach and intestinal tract have different absorption effects for different active ingredient systems. Therefore, although there are many previous cases that have done research on the characteristics of the human digestive system and improved the absorption effect of drugs after entering the human body, there are still many In order to find the best drug absorption rate, it is necessary to cooperate with the different absorption effects of the stomach and intestinal tract for different active ingredients. In particular, the higher the drug absorption rate, the higher the drug efficacy. In addition to being good, it can also reduce the burden on the human body and prevent unabsorbed drugs from remaining in the body.
有鑑於此,本創作人為了提升效性成分在人體內部的吸收率,係嘗試不同結構的錠劑,置入模擬人體消化系統的環境,並經過多次實驗修改,終於設計出本創作的具長效吸收機能結構的錠劑。 In view of this, in order to improve the absorption rate of active ingredients in the human body, the author tried tablets with different structures, placed them in an environment that simulated the human digestive system, and after many experiments and modifications, finally designed this creation. Long-acting absorbent lozenges.
在一實施例中,具長效吸收機能結構的錠劑包括長效核心及速釋外層。長效核心呈片狀。速釋外層包覆長效核心。其中,速釋外層包括基礎成分及潰散成分,基礎成分及潰散成分混合均勻分佈於速釋外層。 In one embodiment, a tablet with an extended-acting absorbent structure includes an extended-acting core and an immediate-release outer layer. The long-wearing core comes in a sheet form. An immediate-release outer layer wraps around a long-lasting core. Wherein, the immediate-release outer layer includes a base component and a collapsible component, and the base component and the collapsible component are mixed and evenly distributed in the immediate-release outer layer.
在一實施例中,基礎成分為速釋外層之重量百分比80%以上,並且潰散成分佔速釋外層之重量百分比20%以下。 In one embodiment, the base component accounts for more than 80% by weight of the immediate-release outer layer, and the collapse component accounts for less than 20% by weight of the immediate-release outer layer.
在一實施例中,長效核心包括第一功效成分第一賦型劑。 第一功效成分至少包括第一膠原蛋白及第一維生素C,並且第一功效成分佔長效核心之重量百分比50%~70%。第一賦型劑佔長效核心之重量百分比30%~50%。 In one embodiment, the long-acting core includes a first active ingredient and a first excipient. The first functional ingredient at least includes the first collagen and the first vitamin C, and the first functional ingredient accounts for 50%-70% by weight of the long-acting core. The first excipient accounts for 30%-50% by weight of the long-acting core.
在一實施例中,基礎成分包括第二功效成分及第二賦型劑。第二功效成分包括第二膠原蛋白及第二維生素C,並且第二功效成分佔基礎成分之重量百分比20%~30%。第二賦型劑佔基礎成分之重量百分比50%~70%。 In one embodiment, the base ingredient includes a second functional ingredient and a second excipient. The second functional component includes the second collagen and the second vitamin C, and the second functional component accounts for 20%-30% by weight of the basic component. The second excipient accounts for 50%-70% by weight of the base component.
在一實施例中,速釋外層的形狀為圓形片狀,並內含形狀為圓形片狀的長效核心。在一實施例中,速釋外層之上、下表面各形成槽線,並在側面形成第一弧面。在一實施例中,長效核心之上、下表面各形成第一粗糙表面,並在側邊形成第二弧面。在一實施例中,速釋外層的形狀為橢圓形,並內含形狀為橢圓形的長效核心。在一實施例中,速釋外層的形狀為橢圓形,並內含形狀為圓形片狀的長效核心。在一實施例中,長效核心之上、下表面各形成第一粗糙表面,並在側邊形成第二弧面。在一實施例中,速釋外層的形狀可為三角形、四角形、蜆狀與中空圓形其中之一或其組合。 In one embodiment, the immediate release outer layer is in the shape of a circular tablet and contains a long-acting core in the shape of a circular tablet. In one embodiment, groove lines are formed on the upper and lower surfaces of the quick-release outer layer, and a first arc surface is formed on the side. In one embodiment, the upper and lower surfaces of the long-lasting core each form a first rough surface, and a second arc surface is formed at a side. In one embodiment, the immediate release outer layer is oval in shape and contains a depot core in oval shape. In one embodiment, the immediate release outer layer is oval in shape and contains a long-acting core in the shape of a circular disc. In one embodiment, the upper and lower surfaces of the long-lasting core each form a first rough surface, and a second arc surface is formed at a side. In one embodiment, the shape of the immediate-release outer layer can be one of triangular, quadrangular, clam-shaped, and hollow circular, or a combination thereof.
在另一實施例中,具長效吸收機能結構的錠劑包括長效核心及速釋外層。長效核心呈片狀並具有第一連結面。速釋外層具有一第二連結面,並且速釋外層包括基礎成分及潰散成分。其中,速釋外層鄰近設置長效核心,並且第二連結面係與第一連結面互相貼合。 In another embodiment, a lozenge with a depot absorbent structure includes a depot core and an immediate release outer layer. The long-lasting core is in the form of a sheet and has a first joint surface. The immediate release outer layer has a second attachment surface, and the immediate release outer layer includes a base component and a disintegrating component. Wherein, the quick-release outer layer is adjacent to the long-acting core, and the second connecting surface is attached to the first connecting surface.
在另一實施例中,第一連結面及第二連結面係皆由複數個弧面所形成,且第一連結面之複數個弧面係與第二連結面之複數個弧面 相對應,使得第一連結面及第二連結面能夠緊密結合。第一連結面及第二連結面設計複數個弧面係為了增加連結面積,以提升連結的強度,如此,於實際製造時,便可依照需求調整複數個弧面。 In another embodiment, both the first connecting surface and the second connecting surface are formed by a plurality of arc surfaces, and the plurality of arc surfaces of the first connecting surface are connected with the plurality of arc surfaces of the second connecting surface Correspondingly, the first connection surface and the second connection surface can be closely combined. A plurality of curved surfaces are designed on the first connecting surface and the second connecting surface to increase the connecting area and enhance the strength of the connection. In this way, the plurality of curved surfaces can be adjusted according to requirements during actual manufacturing.
在另一實施例中,具長效吸收機能結構的錠劑更包括外包裝體。其中,外包裝體包括主體及複數個覆蓋膜。主體具有複數個容置空間,且每一個容置空間係裝填具長效吸收機能結構的錠劑。各個覆蓋膜黏貼並覆蓋於主體的各個容置空間之上,各覆蓋膜具有凸部,而凸部並未黏貼於主體,當覆蓋膜被移除時,則可以輕易取出具長效吸收機能結構的錠劑。 In another embodiment, the lozenge with long-lasting absorption function structure further includes an outer packaging body. Wherein, the outer packaging body includes a main body and a plurality of covering films. The main body has a plurality of accommodating spaces, and each accommodating space is filled with a lozenge with a long-lasting absorption function structure. Each cover film is pasted and covered on each accommodating space of the main body. Each cover film has a convex part, but the convex part is not attached to the main body. When the cover film is removed, the structure with long-lasting absorption function can be easily taken out lozenges.
在另一實施例中,外包裝體的材質為鋁箔、聚丙烯(Polypropylene,PE)、雙軸延伸聚丙烯(Oriented polypropylene)其中之一或其組合。 In another embodiment, the material of the outer package is one of aluminum foil, polypropylene (PE), oriented polypropylene (Oriented polypropylene), or a combination thereof.
本創作之目的,在於提供一種具長效吸收機能結構的錠劑,係針對胃部及腸道不同的特性,設計出可提升人體消化系統吸收率的特殊結構,將效性成分以不同比例壓製成長效核心及速釋外層,讓人體能夠有效吸收膠原蛋白及維生素C等效性成分,並避免未被吸收的藥物殘留在體內,以降低人體的負擔。 The purpose of this creation is to provide a lozenge with a long-lasting absorption structure. According to the different characteristics of the stomach and intestinal tract, a special structure that can improve the absorption rate of the human digestive system is designed, and the active ingredients are suppressed in different proportions. The long-acting core and quick-release outer layer allow the human body to effectively absorb collagen and vitamin C equivalent ingredients, and avoid unabsorbed drugs remaining in the body to reduce the burden on the human body.
為了達成本創作之目的,本案之創作人提出一實施例之具長效吸收機能結構的錠劑,所述實施例的速釋外層的形狀為圓形片狀,所包圍的長效核心形狀為圓形片狀,與其他實施例不同的是,速釋外層之上、下表面各形成槽線,並在側面形成第一弧面,如此,使用者只要沿著槽線便能夠順利地將該具長效吸收機能結構的錠劑剝成兩半;此 外,長效核心之上、下表面各形成第一粗糙表面,並在側邊形成第二弧面,如此,當具長效吸收機能結構的錠劑進入腸道後,第一粗糙表面係可增加作用的面積,縮短緩釋的時間,所以,本實施例中,可依照緩釋時間需求的不同,設計不同粗糙程度的第一粗糙表面。 In order to achieve the purpose of this creation, the creator of this case proposed a lozenge with a long-lasting absorption function structure of an embodiment, the shape of the quick-release outer layer of the described embodiment is a circular sheet, and the surrounded long-acting core has a shape of The disc shape is different from other embodiments in that groove lines are formed on the upper and lower surfaces of the quick-release outer layer, and a first arc surface is formed on the side, so that the user can smoothly release the product along the groove line. The lozenge with long-lasting absorbent structure is peeled in half; the In addition, the upper and lower surfaces of the long-acting core respectively form a first rough surface, and form a second curved surface on the side, so that when the lozenge with long-lasting absorption function structure enters the intestinal tract, the first rough surface can increase The area of action shortens the time of sustained release. Therefore, in this embodiment, the first rough surface with different roughness can be designed according to the requirement of sustained release time.
為了達成本創作之目的,本案之創作人提出一實施例之具長效吸收機能結構的錠劑,在本實施例中,於製作本創作之具長效吸收機能結構的錠劑時,可先將長效核心製作成中空狀,再讓速釋外層包圍長效核心,並同樣為中空狀,使得中空狀的具長效吸收機能結構的錠劑類似傳統食玩:嗶嗶糖;如此,當使用者服用本創作之中空狀的具長效吸收機能結構的錠劑時,可同時吹奏出特殊音調,增加服用的樂趣。 In order to achieve the purpose of this creation, the creator of this case proposed a lozenge with a long-lasting absorption function structure of an embodiment. In this embodiment, when making the lozenge with a long-term absorption function structure of this creation, you can first The long-acting core is made hollow, and the quick-release outer layer surrounds the long-acting core, which is also hollow, so that the hollow lozenge with a long-lasting absorption structure is similar to the traditional food toy: Beep sugar; so, when When the user takes the hollow lozenge with a long-lasting absorption structure, the user can play a special tone at the same time, increasing the pleasure of taking it.
為了達成本創作之目的,本案之創作人提出一實施例之具長效吸收機能結構的錠劑,所述實施例係提供三種實施態樣,在三種實施態樣中,速釋外層的形狀皆為橢圓形,不同的是其中長效核心的態樣,其中,第一種實施態樣,速釋外層的形狀為橢圓形,並內含形狀為圓形片狀的長效核心;第二種實施態樣,速釋外層的形狀為橢圓形,並內含形狀為橢圓形的長效核心;而第三種實施態樣,速釋外層的形狀為橢圓形,並內含形狀為圓形片狀的長效核心,且長效核心之上、下表面各形成第一粗糙表面,並在側邊形成第二弧面,如此,當具長效吸收機能結構的錠劑進入腸道後,第一粗糙表面係可增加作用的面積,縮短緩釋的時間,所以,本實施例中,同樣可依照緩釋時間需求的不同,設計不同粗糙程度的第一粗糙表面。 In order to achieve the purpose of this creation, the creator of this case proposed a lozenge with a long-lasting absorption function structure according to an embodiment. The embodiment provides three implementation forms. In the three implementation forms, the shape of the immediate-release outer layer is different. It is elliptical, and the difference is the form of the long-acting core, wherein, in the first implementation form, the shape of the quick-release outer layer is elliptical, and contains the long-acting core in the shape of a circular sheet; the second In the embodiment, the immediate-release outer layer is oval in shape and contains a long-acting core in the shape of an ellipse; and in the third embodiment, the immediate-release outer layer is in the shape of an ellipse and contains a circular tablet in the shape. Shaped long-acting core, and the upper and lower surfaces of the long-lasting core respectively form a first rough surface, and form a second curved surface on the side, so that when the lozenge with long-lasting absorption function structure enters the intestinal tract, the first The rough surface can increase the area of action and shorten the time of sustained release. Therefore, in this embodiment, the first rough surface with different roughness can also be designed according to the requirements of the sustained release time.
另外,特別的是,在另一些實施例中,速釋外層的形狀可 製成三角形、四角形、或是蜆狀,使得具長效吸收機能結構的錠劑能具有多樣化的型體。 Additionally, particularly, in other embodiments, the shape of the immediate release outer layer can be Made into triangle, quadrangle, or clam shape, the lozenge with long-lasting absorption function structure can have various shapes.
為了達成本創作之目的,本案之創作人提出一實施例之具長效吸收機能結構的錠劑,本實施例與前述實施例大部份的元件皆相同,不同在於,長效核心之上方形成第一粗糙表面,而速釋外層下方則形成第二粗糙表面,其中,增設第一粗糙表面及第二粗糙表面的目的係在於增加作用的面積。因此,可依照需求,設計不同粗糙程度的第一粗糙表面及第二粗糙表面,以控制不同的緩釋時間及崩解時間。 In order to achieve the purpose of this creation, the creator of this case proposed an embodiment of a lozenge with long-lasting absorption function structure. The first rough surface and the second rough surface are formed under the quick-release outer layer, wherein the purpose of adding the first rough surface and the second rough surface is to increase the active area. Therefore, according to requirements, the first rough surface and the second rough surface with different roughness can be designed to control different sustained release times and disintegration times.
1:具長效吸收機能結構的錠劑 1: Tablets with long-lasting absorption structure
10:長效核心 10: long-term core
101:第一粗糙表面 101: first rough surface
102:第二弧面 102: Second arc surface
103:第一連結面 103: The first connecting surface
11:速釋外層 11: quick release outer layer
11a:三角形 11a: Triangle
11b:四角形 11b: quadrangular
11c:蜆狀 11c: clam shape
111:槽線 111: Groove line
112:第一弧面 112: The first arc surface
113:第二連結面 113: The second connecting surface
114:第二粗糙表面 114: second rough surface
2:外包裝體 2: Outer packaging
20:主體 20: subject
201:容置空間 201:Accommodating space
21:蓋片 21: cover sheet
211:凸部 211: convex part
[圖1]是本創作第一實施例之具長效吸收機能結構的錠劑之立體局部剖面圖。 [Fig. 1] is a three-dimensional partial sectional view of the lozenge with long-lasting absorption function structure of the first embodiment of the present invention.
[圖2]是本創作第二實施例之具長效吸收機能結構的錠劑之局部立體剖面圖。 [Fig. 2] is a partial three-dimensional cross-sectional view of a lozenge with a long-lasting absorption function structure according to the second embodiment of the present invention.
[圖3]是本創作第二實施例之具長效吸收機能結構的錠劑之立體圖。 [Fig. 3] is a three-dimensional view of the lozenge with long-acting absorption function structure of the second embodiment of the present invention.
[圖4]是本創作第三實施例之具長效吸收機能結構的錠劑之側視結構剖面圖。 [ Fig. 4 ] is a side view structural cross-sectional view of a lozenge with a long-lasting absorption function structure according to the third embodiment of the present invention.
[圖5]是本創作第三實施例之具長效吸收機能結構的錠劑之立體局部剖面圖。 [Fig. 5] is a three-dimensional partial sectional view of a lozenge with a long-lasting absorption function structure according to the third embodiment of the present invention.
[圖6]是本創作第四實施例之具長效吸收機能結構的錠劑之側視結構剖面圖。 [ Fig. 6 ] is a side view structural cross-sectional view of a lozenge with a long-lasting absorption function structure according to the fourth embodiment of the present invention.
[圖7]是本創作第四實施例之具長效吸收機能結構的錠劑之側視結構剖面圖。 [ Fig. 7 ] is a side view structural cross-sectional view of a lozenge with a long-lasting absorption function structure according to the fourth embodiment of the present invention.
[圖8]是本創作第四實施例之具長效吸收機能結構的錠劑之側視結構剖面圖。 [ Fig. 8 ] is a side view structural cross-sectional view of a lozenge with a long-lasting absorption function structure according to the fourth embodiment of the present invention.
[圖9]是本創作三角形的具長效吸收機能結構的錠劑之立體圖。 [Fig. 9] is a three-dimensional view of the triangular lozenge with long-lasting absorption function structure of the invention.
[圖10]是本創作四角形的具長效吸收機能結構的錠劑之立體圖。 [Fig. 10] is a three-dimensional view of the quadrangular lozenge with long-lasting absorption function structure of the present invention.
[圖11]是本創作蜆狀的具長效吸收機能結構的錠劑之立體圖。 [Fig. 11] is a three-dimensional view of the clam-shaped lozenge with long-lasting absorption function structure of this invention.
[圖12]是本創作第五實施例之具長效吸收機能結構的錠劑之側視結構剖面圖。 [ Fig. 12 ] is a side view structural cross-sectional view of a lozenge with a long-lasting absorption function structure according to the fifth embodiment of the present invention.
[圖13]是本創作第六實施例之具長效吸收機能結構的錠劑之側視結構剖面圖。 [ Fig. 13 ] is a side view structural cross-sectional view of a lozenge with a long-lasting absorption function structure according to the sixth embodiment of the present invention.
[圖14]是本創作具長效吸收機能結構的錠劑之包裝結構前視示意圖。 [Fig. 14] is a schematic front view of the packaging structure of the tablet with the long-lasting absorption function structure of the present invention.
[圖15]是本創作具長效吸收機能結構的錠劑之包裝結構之側視剖面圖。 [Fig. 15] is a side sectional view of the packaging structure of the lozenge with the long-lasting absorption function structure of the present invention.
[圖16]是本創作具長效吸收機能結構的錠劑之包裝結構之側視剖面圖。 [Fig. 16] is a side sectional view of the packaging structure of the lozenge with the long-lasting absorption function structure of the present invention.
為了能夠更清楚地描述本創作所提出之具長效吸收機能結構的錠劑,以下將配合圖式,詳盡說明本創作之較佳實施例。 In order to more clearly describe the lozenge with long-lasting absorption function proposed by this creation, the following will describe the preferred embodiment of this creation in detail in conjunction with the drawings.
首先,先介紹本創作的第一實施例,請參考圖1,係本創作第一實施例之具長效吸收機能結構的錠劑之立體局部剖面圖。如圖1
所示,本創作之具長效吸收機能結構的錠劑1,包括長效核心10及速釋外層11,長效核心10係均質並呈圓形片狀。速釋外層11係均質並呈圓形片狀且包圍長效核心10,並至少具有潰散成分。其中,潰散成分佔速釋外層11之重量百分比20%以下。長效核心10更具有第一賦型劑及第一功效成分,且第一賦型劑佔長效核心10之重量百分比30%~50%,而第一功效成分包括第一膠原蛋白及第一維生素C,並第一功效成分佔長效核心10之重量百分比50%~70%。速釋外層11更具有第二賦型劑及第二功效成分,第二賦型劑佔速釋外層11之重量百分比50%~70%,而第二功效成分包括第二膠原蛋白及第二維生素C,並佔速釋外層11之重量百分比20%~30%。
First of all, the first embodiment of this creation is introduced first. Please refer to FIG. 1, which is a three-dimensional partial sectional view of the lozenge with long-lasting absorption function structure of the first embodiment of this creation. Figure 1
As shown, the
在本創作中,速釋外層11主要係在胃部被溶解,當具長效吸收機能結構的錠劑1進入胃部環境後,速釋外層11會於半小時內崩解,快速釋放出可被胃部吸收之第二效性成分。在一些實施例中,速釋外層11中的第二效性成分的含量少於長效核心10中的第一效性成分的含量,可避免短時間內釋放過多效性成分造成之身體負擔。
In this creation, the quick-release
長效核心10主要係在腸部被溶解,當具長效吸收機能結構的錠劑1從胃部環境進入腸道環境後,長效核心10中的第一效性成分可以穩定釋放6~8小時,有效拉長釋放的時間。如此,能避免大量效性成分在短時間內釋放,減少不必要的副作用及危險性。
The long-acting
在本創作實施例中,第一效性成分及第二效性成分可以是膠原蛋白粉末及維生素C粉末的混合物,然而,膠原蛋白粉末及維生素C粉末僅為本創作之實施例之一,並非用於限制本創作的專利範圍。 In the embodiment of this creation, the first effective ingredient and the second effective ingredient can be a mixture of collagen powder and vitamin C powder, however, collagen powder and vitamin C powder are only one of the embodiments of this creation, not Used to limit the patent scope of this creation.
接著,將介紹本創作第二實施例,請參考圖2,分別係本創作第二實施例之具長效吸收機能結構的錠劑之局部立體剖面圖。具長效吸收機能結構的錠劑1,包括長效核心10及速釋外層11。速釋外層11係均質且包圍長效核心10。與第一實施例不同的是,速釋外層11之上、下表面各形成槽線111,並在側面形成第一弧面112,如此,使用者只要沿著槽線111便能夠順利地將該具長效吸收機能結構的錠劑1簡單地剝成兩半。此外,該長效核心10之上、下表面各形成第一粗糙表面101。如此,當食用者服用該具長效吸收機能結構的錠劑1時,其進入口腔中,速釋外層11會於半小時內崩解,而當該具長效吸收機能結構的錠劑1進入腸道後,第一粗糙表面101係可增加作用的面積,縮短緩釋的時間,所以,本實施例中,可依照緩釋時間需求的不同,設計不同粗糙程度的第一粗糙表面101。
Next, the second embodiment of this creation will be introduced. Please refer to FIG. 2, which are partial three-dimensional cross-sectional views of lozenges with a long-lasting absorption function structure according to the second embodiment of this creation. A
接著,將介紹本創作第二實施例另一態樣,請參考圖3,係本創作第二實施例之具長效吸收機能結構的錠劑之立體圖。如圖3所示,本創作第二實施例的速釋外層11的形狀為橄欖形片狀,所包圍的長效核心10形狀為圓形片狀,與第一實施例不同的是,速釋外層11之上、下表面各形成一槽線111,並在側面形成第一弧面112,如此,使用者只要沿著槽線111便能夠順利地將該具長效吸收機能結構的錠劑1剝成兩半。
Next, another aspect of the second embodiment of the present invention will be introduced. Please refer to FIG. 3 , which is a three-dimensional view of the lozenge with long-lasting absorption function structure of the second embodiment of the present invention. As shown in Figure 3, the shape of the quick-release
請參考圖4及圖5,分別係本創作第三實施例之具長效吸收機能結構的錠劑之側視結構剖面圖,及本創作第三實施例之具長效吸收機能結構的錠劑之立體局部剖面圖。如圖4及圖5所示,在本創作第三實
施例中,於製作本創作之具長效吸收機能結構的錠劑1時,可先將該長效核心10製作成中空環狀,再讓速釋外層11包圍長效核心10,並同樣為中空環狀,使得環狀的具長效吸收機能結構的錠劑1類似傳統食玩:嗶嗶糖。如此,當使用者服用本創作之環狀的具長效吸收機能結構的錠劑1時,可同時吹奏出特殊音調,增加服用的樂趣。
Please refer to Fig. 4 and Fig. 5, which are respectively the side-view structure sectional view of the lozenge with the long-acting absorption function structure of the third embodiment of the invention, and the lozenge with the long-acting absorption function structure of the third embodiment of the invention The three-dimensional partial section view. As shown in Figure 4 and Figure 5, in the third practice of this creation
In the embodiment, when making the
請參考圖6至圖8,係本創作第四實施例之具長效吸收機能結構的錠劑之側視結構剖面圖;本創作第四實施例係提供三種實施態樣,在三種實施態樣中,速釋外層11的剖面形狀皆為橢圓形,不同的是長效核心10的態樣。其中,在圖6中,速釋外層11的形狀為橢圓形,並內含形狀為片狀的長效核心10。在圖7中,速釋外層11的形狀為橢圓形,並內含形狀為橢圓形的長效核心10。而在圖8中的速釋外層11的形狀為橢圓形,並內含形狀為圓形片狀的長效核心10,且長效核心10之上、下表面各形成第一粗糙表面101,並在側邊形成第二弧面102。如此,同樣地,當具長效吸收機能結構的錠劑1進入腸道後,第一粗糙表面101係可增加作用的面積,縮短緩釋的時間,所以,在第四實施例中,同樣可依照緩釋時間需求的不同,設計不同粗糙程度的第一粗糙表面101。
Please refer to Fig. 6 to Fig. 8, which are the side view structural sectional views of the lozenge with long-acting absorption function structure of the fourth embodiment of the invention; Among them, the cross-sectional shapes of the quick-release
請參考圖9至圖11,分別係本創作三角形、四角形、及蜆狀的具長效吸收機能結構的錠劑之立體圖。如圖9至圖11所示,速釋外層的形狀可製成三角形11a、四角形11b、或是蜆狀11c,使得該具長效吸收機能結構的錠劑1能具有多樣化的型體。
Please refer to Figures 9 to 11, which are three-dimensional views of the triangular, quadrangular, and clam-shaped lozenges with long-lasting absorption function structures. As shown in Figures 9 to 11, the shape of the immediate-release outer layer can be made into a
接著,請參考圖12,係本創作第五實施例之具長效吸收機能結構的錠劑之側視結構剖面圖。如圖12所示,本創作第五實施例之具
長效吸收機能結構的錠劑1包括長效核心10及速釋外層11。長效核心10係均質並呈片狀,並具有第一連結面103。速釋外層11具有第二連結面113,並至少具有潰散成分。其中,速釋外層11係設置在長效核心10之下方,且第二連結面113係與第一連結面103相互貼合。在一些實施例中,第一連結面103及第二連結面113係皆由複數個弧面所形成,且第一連結面103之複數個弧面係與第二連結面113之複數個弧面相對應,使得第一連結面103及第二連結面113彼此的貼合面積大幅增加,強化其貼合力。
Next, please refer to FIG. 12 , which is a cross-sectional side view of the lozenge with a long-lasting absorption function structure according to the fifth embodiment of the present invention. As shown in Figure 12, the tool of the fifth embodiment of the present invention
The
在本創作第五實施例中,第一連結面103及第二連結面113設計複數個弧面係為了增加連結面積,以提升連結的強度,如此,於實際製造時,便可依照需求調整該複數個弧面,或其他可增加面積的造型設計。
In the fifth embodiment of the present invention, the
接續上述,長效核心10更具有第一賦型劑及第一功效成分,且第一賦型劑佔長效核心10之重量百分比30%~50%,而第一功效成分包括第一膠原蛋白及第一維生素C,並佔長效核心10之重量百分比50%~70%。而速釋外層11更具有第二賦型劑及第二功效成分,且第二賦型劑佔速釋外層11之重量百分比50%~70%,而第二功效成分包括第二膠原蛋白及第二維生素C,並佔速釋外層11之重量百分比20%~30%。
Continuing from the above, the long-acting
另外,請參考圖13,係本創作第六實施例之具長效吸收機能結構的錠劑之側視結構剖面圖。如圖13所示,本創作第六實施例與第五實施例大部份的元件皆相同,不同在於,長效核心10之上方形成第一粗糙表面101,而速釋外層11下方則形成第二粗糙表面114。其中,第
一粗糙表面101及第二粗糙表面114的目的係在於增加作用的面積。因此,可依照需求,設計不同粗糙程度的該第一粗糙表面101及第二粗糙表面114,以控制不同的緩釋時間及崩解時間。
In addition, please refer to FIG. 13 , which is a side view structural cross-sectional view of a lozenge with a long-lasting absorption function structure according to the sixth embodiment of the present invention. As shown in Figure 13, most of the components of the sixth embodiment of the present invention are the same as those of the fifth embodiment, the difference is that a first
接著介紹本創作具長效吸收機能結構的錠劑的包裝方式,請參考圖14至圖16。其中,圖14係本創作具長效吸收機能結構的錠劑之包裝結構前視示意圖,圖15及圖16則係本創作具長效吸收機能結構的錠劑之包裝結構之側視剖面圖。如圖14所示,本創作之具長效吸收機能結構的錠劑1係可被容置在外包裝體2的內部。外包裝體2係包括主體20,具有複數個容置空間201,且每一個容置空間201可以裝填一個具長效吸收機能結構的錠劑1(圖14並未繪出)。蓋片21係黏貼並覆蓋於主體20的容置空間201之上,並具有凸部211,並且凸部211並未黏貼於主體20。其中,任一使用者可自凸部211將蓋片21撕開,以取出具長效吸收機能結構的錠劑1;此外,外包裝體2的材質為鋁箔、聚丙烯(Polypropylene,PE)、或是雙軸延伸聚丙烯(Oriented polypropylene)。
Next, we will introduce the packaging method of the tablet with the long-lasting absorption function structure of the present invention, please refer to Fig. 14 to Fig. 16 . Wherein, Fig. 14 is a front view schematic diagram of the packaging structure of the lozenge with the long-acting absorption function structure of the present invention, and Fig. 15 and Fig. 16 are side sectional views of the packaging structure of the lozenge with the long-acting absorption function structure of the present invention. As shown in FIG. 14 , the
接續上述,如圖15所示,每一個具長效吸收機能結構的錠劑1係容置於主體20之容置空間201內,再藉由蓋片21封裝起來,以保持具長效吸收機能結構的錠劑1能在密封的狀態下容置於容置空間201內。需要使用時,只需自凸部211將蓋片21撕開,便可取出具長效吸收機能結構的錠劑1來服用。此外,如圖16所示,蓋片21可被擠開,因此,本創作所提供的外包裝體2還能夠以擠壓的方式取出具長效吸收機能結構的錠劑1。由此可知,本創作所提供之外包裝體2共有二種取出方式,包括將蓋片21撕開,以及從主體20向容置空間201方向擠壓蓋片21,使
蓋片21自然脫離主體20,相當便利。
Continuing the above, as shown in FIG. 15 , each
本創作人提供一製成本創作具長效吸收機能結構的錠劑1的配方,首先,取25毫克潰散成分粉末、150毫克賦型劑粉末及75毫克維生素C粉末均勻混合,再以加壓製錠的方式製成速釋外層,接著,取100毫克賦型劑粉末及150毫克膠原蛋白粉末,均勻混合後,與速釋外層一同加壓製錠,即可獲得本創作具長效吸收機能結構的錠劑1,特別的是,本創作具長效吸收機能結構的錠劑1可做為健康食品或醫藥品。
The author provides a formula for making the
經由上述可知,本創作所提供之具長效吸收機能結構的錠劑1,具有可提升人體消化系統吸收率的特殊結構,將效性成分以不同比例壓製成長效核心及速釋外層,同時針對胃部及腸道不同的特性,讓人體能夠有效吸收膠原蛋白及維生素C等效性成分,並避免未被吸收的藥物殘留在體內,以降低人體的負擔。
From the above, it can be known that the
上述之詳細說明係針對本創作可行實施例之具體說明,惟該實施例並非用以限制本創作之專利範圍,凡未脫離本創作技藝精神所為之等效實施或變更,均應包含於本案之專利範圍中。 The above detailed description is a specific description of the feasible embodiment of this creation, but this embodiment is not used to limit the patent scope of this creation, and any equivalent implementation or change that does not deviate from the spirit of this creation should be included in this case within the scope of the patent.
1:具長效吸收機能結構的錠劑 1: Tablets with long-lasting absorption structure
10:長效核心 10: long-term core
11:速釋外層 11: quick release outer layer
Claims (18)
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| TW111203396U TWM632571U (en) | 2022-04-01 | 2022-04-01 | Lozenges with long-lasting absorption function structure |
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| TW111203396U TWM632571U (en) | 2022-04-01 | 2022-04-01 | Lozenges with long-lasting absorption function structure |
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