TWM552024U - Bio-medication conveying box - Google Patents

Description

Biological agent shipping box

This creation is related to the shipping box, and in particular to a shipping box that avoids collisions during the delivery of the biological product to maintain the stability and temperature of the biological agent during transport.

Most of the components in the body are often mature and fully differentiated cells, such as skin cells, liver cells, or oral cells. The characteristics of these cells, without any external stimulation or mutation, are usually thought to have determined the fate of the cells and will not be converted to other cells. Such cells are commonly referred to as "somatic cells". Stem cells are significantly different from these differentiated somatic cells. Stem cell system refers to the original cells that have not yet fully differentiated and have differentiation and can differentiate into two or more mature cells. They can be stimulated in various ways to change the fate of cells and differentiate into specific cells. Cell.

The stem cells are classified into differentiation cells, which can be divided into totipotent stem cells, pluripotent stem cells, multipotent stem cells and unipotent stem cells; It can be divided into embryonic stem cells, somatic stem cells and induced pluripotent stem cells (iPSC). Among them, the human embryonic stem cell line belongs to the omnipotent stem cell, which is derived from the cell mass in the blastocyst stage before implantation, and has omnipotence and can be differentiated into various adult cells; in addition, the induced univalent stem cell is forced to perform ( Enforced expression) The method of manipulating a specific gene or protein into a differentiated somatic cell, such that the somatic cell is reprogrammed to become an embryonic stem cell. According to medical research, stem cells have the potential to repair tissues or organs, and can be applied to various applications such as treating cancer, repairing organs, developing new drugs, and manufacturing artificial organs, and can change human response to diseases.

The method of preserving stem cells is generally to store stem cells in a container, such as a centrifuge tube and store them in a low-temperature environment such as a refrigerator, or to prepare stem cells into a liquid preparation or an injection preparation. When the stem cells are to be transported, the preparation or container for storing the stem cells is placed in an insulated refrigerator or ice bucket, and ice cubes are cooled in a mobile refrigerator or ice bucket to preserve the stem cells in a low temperature environment. The effect of transporting stem cells.

Although the above-mentioned method of transporting stem cells in a mobile refrigerator or an ice bucket can achieve the effect of transporting a stem cell preparation or a container, since the mobile refrigerator and the ice bucket are large in size, even if only a small amount of stem cells are transported, the mobile refrigerator should be filled with ice. The block can keep the interior at a low temperature, but this has the disadvantage of inconvenient transportation and waste of ice, and the container is easily shaken during transportation to cause collision, resulting in decreased cell activity or even death.

In view of this, the present invention relates to a shipping box, and more particularly to a shipping box capable of avoiding collisions during the delivery of a biological preparation product to maintain the stability and temperature of the biological preparation during transportation, as its main purpose.

The creation utilizes each of the accommodating holes for accommodating and positioning the biological preparation product, so that the biological preparation product does not sway during transportation, and the biological product product can be prevented from being damaged by collision, and the inside of the box can maintain a low temperature environment. To achieve the purpose of maintaining the activity of biological agents.

According to the above technical feature, the cold insulation structure is a dry ice, a freezing bag, a cold preservation agent or a power consuming cooling assembly.

According to the above technical feature, the temperature recorder has a temperature sensor, a transmission unit, and a storage unit respectively connected to the temperature sensor and the transmission unit.

According to the above technical feature, the transmission unit is a wired transmission interface or a wireless transmission interface.

According to the above technical feature, the cover body is further provided with a positioning hole corresponding to the receiving hole on a side of the cover body.

According to the above technical feature, the first and second bodies have a first accommodating space for accommodating the temperature recorder, and the first opening of the first accommodating space is at the first opening. The top plate is provided, and the top plate is provided with a plurality of accommodating holes for accommodating the biological product; the second body has a second accommodating space for accommodating the cold storage structure, and the first and second body portions At least one assembled configuration is provided.

According to the above technical feature, the assembly structure is a protruding portion and a concave portion that are engaged with each other.

According to the above technical feature, the cell product is a biologic container and is provided with a tube body, and a plug is attached to the top end of the tube body.

According to the above technical feature, the biologic product is a stem cell preparation.

In order to understand the technical characteristics, content and advantages of the creation and the effects that can be achieved by the examiner, the author will use the drawings in detail and explain the following in the form of the examples, and the drawings used therein The subject matter is only for the purpose of illustration and supplementary instructions. It is not necessarily the true proportion and precise configuration after the implementation of the original creation. Therefore, the proportions and configuration relationships of the attached drawings should not be interpreted or limited in the actual implementation scope. First described.

Please refer to Fig. 1 for a perspective view of the structure of the transport case in the present creation, and Fig. 2 is a perspective view showing the structure of the cover opening in the present creation, and Fig. 3 is an exploded view of the structure of the transport case in the present creation. The bio-reporting box 1 of the present invention is mainly provided with a box body 10 and a lid body 20 coupled to the top of the box body 10. The box body 10 and the lid body 20 can be made of a heat insulating material. The box body 20 is 20 An accommodating space 21 is provided for accommodating a cold storage structure 30 and a temperature recorder (not shown). A top plate 22 is disposed at one of the tops of the accommodating space 21 to cover the accommodating space 21 Opening, and the top plate 22 is provided with a plurality of receiving holes 221 for receiving the biological product 40. The biological product 40 may be a stem cell preparation or a stem cell container. In the preferred embodiment of the present invention, the biological product 40 is a rocket. A centrifuge tube (which is a type of stem cell container) is provided with a tube body 41, and a plug cap 42 is attached to the tip end of the tube body 41 to close the tube body 41.

In actual use, please refer to FIG. 3 and FIG. 4 , first place the cold insulation structure 30 and the temperature recorder (not shown) in the accommodating space 21 , and then place the top plate 22 on the top of the accommodating space 21 . At the opening, the plurality of biologic products 40 are placed in the accommodating hole 221, and the cover 20 is covered on the top of the casing 10 to form a sealed accommodating space in the casing 10, and the internal cold-keeping structure is utilized. 30, the lower temperature can be maintained in the accommodating space 21 for a certain period of time, and the biological preparation products 40 can be accommodated by the accommodating holes 221 and individually positioned one by one, so that the biological product 40 is not transported during transportation. The shaking can avoid the damage of the biological product 40 caused by the collision, and the inside of the box 10 can maintain a low temperature environment, thereby achieving the purpose of maintaining the activity of the biological preparation.

Wherein, the above-mentioned cold storage structure is dry ice, a freezing bag, a cold preservation agent or a power consuming cooling component (for example, a cooling chip connected to a battery), and the above temperature recorder has a temperature sensor, a transmission unit, and a separate a storage unit connected to the temperature sensor and the transmission unit, wherein the transmission unit is a wired transmission interface or a wireless transmission interface, and the temperature of the sensing space sensed by the temperature sensor can be transmitted to the outside through the transmission interface, for example The manager can obtain the temperature change of the biological agent delivery box stored in the temperature recorder through the electronic component (such as a computer or a mobile phone) and its wireless transmission interface, so as to record the temperature change state of the biological product during the delivery process of the biological product. . In this way, the consignor and the consignee can be assisted to confirm whether the temperature status of the biologic product in the transportation process is in compliance with the regulations, so as to determine the attribution of responsibility when the problem occurs.

In addition, as shown in FIG. 5 , the cover body 20 is further provided with a plurality of positioning holes 23 corresponding to the receiving holes 221 on one side of the cover body 10 . After the cover 20 is covered by the case 10, the positioning hole 23 can be inserted into the cover 42 of the biological product 40 to further increase the fixing effect.

The above-mentioned biological preparation may be a stem cell preparation or a stem cell container, and different stem cell containers may also be used for different purposes of transportation, for example, when the tissue is taken from the provider, the tissue storage needs to be placed as shown in Fig. 2. The body of the rocket-shaped centrifuge tube is placed in a transport box and transported to a laboratory for cultivation, separation, and the like to obtain stem cells; if it is transported by a laboratory-completed stem cell preparation, the stem cell preparation is placed as in the first In the syringe 43 shown in FIG. 6, the syringe 43 is covered with a film 44 to maintain the sterile environment of the syringe 43. After the syringe 43 is housed in the transport case, the entire transport box is further and further The film can be coated to further ensure that the stem cell preparation is not contaminated.

In summary, the present invention provides a preferred and feasible biological agent delivery box, and submits a new patent application according to law; the technical content and technical features of the present invention are disclosed above, but those familiar with the technology may still be based on this The creation of the creation and the various changes and modifications that do not depart from the creative spirit of the case. Therefore, the scope of the present invention is not limited to the embodiments disclosed, but includes various alternatives and modifications that do not depart from the present invention and are covered by the following claims.

1‧‧‧Biological delivery box
10‧‧‧Box
20‧‧‧ cover
21‧‧‧ accommodating space
22‧‧‧ top board
221‧‧‧ accommodating holes
23‧‧‧Positioning holes
30‧‧‧ cold insulation structure
40‧‧‧Biological products
41‧‧‧ tube body
42‧‧‧Segai
43‧‧‧Syringe
44‧‧‧film

Fig. 1 is a perspective view showing the structure of the transport case in the present creation. Figure 2 is a perspective view showing the structure of the lid opening in the creation. Figure 3 is an exploded view of the transport case in the present creation. Figure 4 is a schematic view showing the structure of the transport case in the present creation. Fig. 5 is a schematic view showing another structure of the transport case in the present creation. Figure 6 is a schematic view showing the structure of the stem cell container in the present creation.

1‧‧‧Biological delivery box

10‧‧‧Box

20‧‧‧ cover

21‧‧‧ accommodating space

22‧‧‧ top board

221‧‧‧ accommodating holes

30‧‧‧ cold insulation structure

40‧‧‧Biological products

Claims (10)

A biological agent transporting box is mainly provided with a box body and a cover body coupled to the top of the box body, the box body having an accommodating space for accommodating a cold storage structure and a temperature recorder, one of the tops of the accommodating space A top plate is disposed at the opening to cover the opening of the accommodating space, and the top plate is provided with a plurality of accommodating holes for accommodating the biological product. The biological preparation transport case according to claim 1, wherein the cold preservation structure is a dry ice, a freezing bag, a cold preservation agent or a power consuming cooling assembly. The biological agent transport case of claim 1, wherein the temperature recorder has a temperature sensor, a transmission unit, and a storage unit respectively connected to the temperature sensor and the transmission unit. The biologics transport kit of claim 3, wherein the transport unit is a wired transmission interface or a wireless transmission interface. The biological agent transporting case according to any one of claims 1 to 4, wherein the cover body is further provided with a positioning hole corresponding to the receiving hole on a side of the cover body. The biological agent transporting cartridge according to any one of claims 1 to 4, wherein the cartridge has a first body and a second body, the first body having a first accommodating space for accommodating the temperature recorder. The top plate is provided at a first opening of the top of the first accommodating space, and the top plate is provided with a plurality of accommodating holes for accommodating the biological product; the second body has a second accommodating space for accommodating The cold insulation structure is provided with at least one assembly structure between the first and second bodies. The biological preparation transport case according to claim 6, wherein the assembly structure is a protruding portion and a concave portion that are engaged with each other. The biological preparation delivery case according to any one of claims 1 to 4, wherein the biological preparation product is a rocket type centrifuge tube and is provided with a tube body, and a plug cover is attached to the top end of the tube body. The biological agent delivery case according to any one of claims 1 to 4, wherein the biological preparation product is a syringe coated with a film. The biological agent delivery kit according to any one of claims 1 to 4, wherein the biological preparation product is a stem cell preparation.