TWI814002B - Ventilator connectable to airway of living patient, apparatus suitable for use with respirator and method of using the same - Google Patents

Abstract

An apparatus such as a fluid mixer, suitable for use with a respirator, including a venturi nozzle for flow of a pressure-controlled fluid; an ambient fluid aperture in fluid communication with the venturi nozzle; a fluid port; a pressure force multiplier in fluid communication with the fluid port; and a valve moveable relative to the venturi nozzle between a start flow position and a stop flow position; where the pressure force multiplier is configured such that fluid forced into the fluid port actuates the valve relative to the venturi nozzle; and where the pressure force multiplier is configured such that fluid withdrawn from the fluid port actuates the valve relative to the venturi nozzle. A method of using an apparatus suitable for a ventilator is also disclosed.

Description

Respirators connectable to the airway of a living patient, equipment suitable for use with the ventilator, and methods of using the same

The present invention generally relates to a fluid mixing device, and more particularly, the present invention relates to fluid mixing in a respirator such as a respirator that may be used in human patients suffering from respiratory symptoms of a disease such as COVID-19 or a chronic respiratory disease. Equipment and methods of using such respirators.

As of the filing date of this invention, a COVID-19 virus pandemic is sweeping the world. COVID-19 has many symptoms, but is primarily a respiratory illness. Most people exposed to the COVID-19 virus have mild symptoms (if any) and quickly return to full health. However, a very small number of people have extremely severe reactions to exposure to the COVID-19 virus. In these people, the lungs become infected and inflamed, filling the alveoli with pus or fluid and becoming blocked, interfering with the transfer of oxygen to the capillaries. The sickest patients, who respond poorly to the COVID-19 virus, suffer from acute respiratory distress syndrome (ARDS). The lungs of patients with ARDS are severely damaged by the COVID-19 virus and their alveoli become filled with fluid. The naturally occurring surfactant in the lungs that helps the alveoli expand and shrink is destroyed, making the lungs stiffer. In addition, inflammation from ARDS increases the gap between the inner surface of the alveoli and adjacent microvessels to further reduce oxygen transfer to the microvessels. Patients suffering from these extreme symptoms from COVID-19 infection or other causes must be intubated and connected to a ventilator to push oxygen to their lungs and transfer modified oxygen to the blood.

Intubation and ventilation as much as possible may be the last line of defense between life and death for patients suffering from severe symptoms of COVID-19 infection and other patients with ARDS. Ventilation is invasive and expensive; it does nothing to help breathing and complete An additional step between intubation and ventilation would be beneficial. Additionally, current respirators can discharge droplets exhaled by the patient into the patient's surroundings (usually a hospital ward or an intensive care unit). These droplets often carry the COVID-19 virus from infected patients and put health care workers and other patients at risk.

Additionally, current respirators rely on a continuous supply of compressed oxygen to function properly; operation of these current respirators requires a continuous flow of oxygen supply. This continuous flow wastes oxygen and increases cost and makes current respirators unsuitable for remote locations, locations in less developed countries, or other locations where a large and continuous supply of oxygen is unavailable or has limited opportunity to use a large and continuous oxygen supply. Similarly, existing respirators rely on electronics to control the respirator and electricity to power the electronics. This need for electricity also makes current respirators unsuitable for remote locations, locations in less developed countries, or other locations where continuous power is unavailable or has limited opportunity.

Therefore, there is a need for an improved respirator that is less invasive to the patient and exposes those in the vicinity of the ventilated patient to less risk of infection.

In addition, health care inequity is very prominent around the world, especially in low- and middle-income countries (LMIC) such as India. Traditional ventilation methods are expensive and generate an economic burden of billions of dollars each year in the United States alone. In LMICs, the use of respiratory care devices such as respirators is limited not only by these high costs but also by a lack of resources such as power distribution. Traditional ventilation methods are limited in their ability to treat people's various respiratory needs around the world because they are very delicate and require extensive infrastructure to operate, including a clean space, a power source, and normal care and maintenance to maintain optimal performance. condition.

Additionally, both the clinical performance of conventional ventilation system monitoring devices and the device's patient system interaction are anticipated. There is a gap in monitoring patient compliance with their physician's orders regarding the use of respiratory therapy devices. Verification of compliance is an important step in enabling a medical device company to receive reimbursement. Without any verification, the company cannot reimburse the cost of supplying its equipment.

There is a need for a new approach to ventilation devices in the medical field that at least partially addresses the deficiencies associated with traditional ventilation devices. In particular, it is desirable to provide a ventilation device that can provide treatment to patients in LMICs that lack infrastructure and electricity and can monitor patient compliance (which is key for medical device companies to receive reimbursement for supplying devices to patients) One device.

According to some embodiments, a ventilator may be mechanical, relying on the patient's natural breathing to control the flow of air into a ventilator. The airflow provided is at a pressure slightly above ambient pressure and may also be enriched with oxygen to aid patients with breathing difficulties. According to some embodiments, rather than relying on electronics to control air flow, a simple and robust mechanical valve is used to shut off the flow of compressed air and/or oxygen into the venturi inlet. The valve is activated by small pressure changes produced when the patient breathes naturally. The valve can be based on a simple diaphragm and flap valve system, a bistable diaphragm system or a spring-loaded shuttle system.

According to an aspect of the present invention, a respirator is provided, which includes: a venturi nozzle for the flow of a pressure-controlled fluid; a surrounding fluid pore in fluid communication with the venturi nozzle; a fluid port ; a pressure multiplier in fluid communication with the fluid port; and a valve movable relative to the venturi nozzle between a start flow position and a stop flow position; wherein the pressure multiplier is configured such that Fluid forced into the fluid port actuates the valve relative to the venturi nozzle; and wherein the pressure multiplier is configured such that fluid withdrawn from the fluid port actuates the valve relative to the venturi nozzle.

According to an aspect of the invention, a respirator connectable to the airway of a living patient is provided, which includes: a venturi including a throat; a venturi nozzle; a venturi in the venturi nozzle an opening through which pressure-controlled oxygen flows outwardly, wherein the venturi opening leads to the throat, and wherein the venturi opening and the throat are substantially longitudinally aligned; and a surrounding air void that is aligned with the throat The nozzle is in fluid communication with the surrounding air; a fluid port is in fluid communication with the airway of the patient; a pressure multiplier is in fluid communication with the fluid port, wherein the pressure multiplier includes at least one opening defined therethrough ; the pressure multiplier includes at least one cover movable between an open position and a closed position relative to the at least one opening; and a valve that can cause the flow of pressure-controlled oxygen to divert the ambient air between entraining the flow of pressure-controlled oxygen to a stop-flow position in the throat and stopping the flow of pressure-controlled oxygen to entrain the ambient air to a stop-flow position in the throat relative to the venturi in the venturi nozzle The tube opening moves along an axis of movement; wherein the pressure multiplier is configured such that the patient exhales into the fluid port actuating the valve along the axis of movement relative to the venturi nozzle to close the venturi nozzle; wherein The pressure multiplier is configured such that the patient's inhalation through the fluid port actuates the valve along the axis of movement relative to the venturi nozzle; and wherein the axis of movement of the valve is substantially consistent with a longitudinal direction of the throat Longitudinal alignment.

According to an aspect of the invention, a respirator connectable to the airway of a living patient is provided, which includes: a venturi including a throat; a venturi nozzle; a venturi in the venturi nozzle an opening through which pressure-controlled oxygen flows outwardly, wherein the venturi opening leads to the throat, and wherein the venturi opening and the throat are substantially longitudinally aligned; and a surrounding air void that is aligned with the throat The nozzle is in fluid communication with the surrounding air; a fluid port is in fluid communication with the airway of the patient; a pressure multiplier is in fluid communication with the fluid port, wherein the pressure multiplier includes at least one opening defined therethrough ; The pressure multiplier includes at least one cover movable between an open position and a closed position relative to the at least one opening; and a valve that can cause Between the flow of pressure controlled oxygen entraining the ambient air to a start flow position in the throat and stopping the flow of pressure controlled oxygen entraining the ambient air to a stop flow position in the throat moves along an axis of movement relative to the venturi opening in the venturi nozzle; wherein the pressure multiplier is configured such that the patient exhales into the fluid port relative to the venturi nozzle along the axis of movement actuating the valve to close the venturi nozzle; wherein the pressure multiplier is configured such that the patient's inhalation through the fluid port actuates the valve along the axis of movement relative to the venturi nozzle; wherein the movement of the valve The axis is substantially longitudinally aligned with a longitudinal direction of the throat; and includes at least one of a sensor, a measuring device, and a power generating device positioned between at least one of: the venturi nozzle and the surrounding air void; and the pressure multiplier and the fluid port; and wherein at least one of the sensor, measurement device and power generation device includes at least one of the following: a pressure sensor, an oxygen sensor, Carbon dioxide sensors, temperature sensors, humidity sensors, piezoelectric sensors, piezoelectric generators, spirometry measuring devices, pitot measuring probes and spirometry generators.

At least one of the sensor, measurement device and power generation device can be positioned between the venturi nozzle and the surrounding air void, and at least one of the sensor, measurement device and power generation device can be positioned between between the pressure multiplier and the fluid port.

To collect differential data, at least one of the sensor, measurement device, and power generation device may be positioned between the venturi nozzle and the surrounding air void, and one of the same type of sensor, measurement device, and At least one of the power generation devices may be positioned between the pressure multiplier and the fluid port.

The respirator may include a central processing unit for packaging raw data collected by at least one of the sensor, measurement device, and power generation device.

The respirator may include a motion sensor.

The respirator may include means for allowing fluid to leave the respirator during exhalation. Exhalation windows and a fluid flow restrictor for at least selectively partially closing the expiration windows to set the patient's positive end-expiratory pressure (PEEP). The fluid flow limiter allows the respirator to limit the amount of air leaving the respirator for a set period thereby prolonging the expiratory period and thereby allowing the patient's PEEP to be modified to a safe level to avoid, for example, lung shrink. Additionally, intubated patients often require further procedures such as CT scans, which require the patient to be transferred from one breathing device to another. This procedure of mechanically transporting ventilated patients can cause various health problems for the patients. In one patient, a brief period of disconnection from ventilation resulted in loss of positive end-expiratory pressure (PEEP) and reduced functional residual capacity (FRC). A significant reduction in one of the FRC in patients with severe acute respiratory distress syndrome can cause worsening of hypoxemia. In some cases, it can take several hours to increase the FRC and eliminate hypoxia. The present invention at least partially solves this problem found in traditional transport ventilation methods by eliminating the PEEP decrease when switching a patient from an emergency intensive care ventilator to a transport ventilator and back again, resulting in significantly improved patient care.

According to another aspect, the present invention contemplates a device suitable for use with a ventilator, which includes: a venturi including a throat, a venturi nozzle, and the pressure-controlled fluid through which outward flow a venturi opening in the venturi nozzle, wherein the venturi opening leads to the throat, and wherein the venturi opening and the throat are substantially longitudinally aligned; a surrounding fluid pore with the venturi a nozzle in fluid communication with an ambient fluid; a fluid port; a pressure multiplier in fluid communication with the fluid port; and a valve capable of entraining the ambient fluid to the Between a start flow position in the throat and a cessation of flow of the pressure controlled fluid entraining the surrounding fluid to a stop flow position in the throat relative to the venturi opening in the venturi nozzle along a the axis of movement moves; wherein the pressure multiplier is configured such that fluid forced into the fluid port actuates the valve along the axis of movement relative to the venturi nozzle to close the venturi nozzle; wherein the pressure multiplier is Configured so that fluid withdrawn from the fluid port is relative to the A venturi nozzle actuates the valve along the axis of movement; wherein the axis of movement of the valve is substantially longitudinally aligned with a longitudinal direction of the throat; wherein the pressure multiplier is positioned between the venturi nozzle and the fluid port between; and includes at least one of a sensor, a measurement device, and a power generation device positioned between at least one of: the venturi nozzle and the surrounding fluid aperture; and the pressure multiplier and the Fluid port; and wherein at least one of the sensor, measuring device and power generation device includes at least one of the following: a pressure sensor, an oxygen sensor, a carbon dioxide sensor, a temperature sensor, a humidity sensor instruments, piezoelectric sensors, piezoelectric generators, spirometer measuring devices, pitot measuring probes and spirometer generators.

At least one of the sensor, measurement device and power generation device can be positioned between the venturi nozzle and the surrounding air void, and at least one of the sensor, measurement device and power generation device can be positioned between between the pressure multiplier and the fluid port.

To collect differential data, at least one of the sensor, measurement device, and power generation device may be positioned between the venturi nozzle and the surrounding air void, and one of the same type of sensor, measurement device, and At least one of the power generation devices may be positioned between the pressure multiplier and the fluid port.

The apparatus may include a central processing unit for packaging raw data collected by at least one of the sensor, measurement device, and power generation device.

The device may include a motion sensor.

The device may include at least one fluid gate for allowing fluid to exit the device when fluid is forced into the fluid port and a fluid flow restrictor for at least selectively partially closing the at least one fluid gate.

The apparatus may further comprise a pressure regulator for regulating the flow of the pressure controlled fluid, the pressure regulator comprising: a housing formed to contain an inner bore; a piston movably disposed within the bore, wherein the piston includes an annular lip adjacent a first end thereof; a spring disposed within the bore and including a first end and a second end; an adjustment cap movably disposed in the inner hole, wherein the adjustment cap is formed to include a plurality of keyways formed therein; wherein: the first end of the spring and the annular The lips are in physical contact; and the second end of the spring is in physical contact with the adjusting cap, wherein: rotating the adjusting cap in a first direction causes the adjusting cap to compress the first spring; rotating the adjusting cap in a second and opposite direction The adjusting cap causes the adjusting cap to decompress the spring; rotating the adjusting cap along the first direction increases the output pressure of the pressure regulator; rotating the adjusting cap along the second direction reduces the output pressure of the pressure regulator; The inner bore is defined by a cylindrical wall; the cylindrical wall is formed to include a first thread therein; the adjustment cap is formed to include a second thread formed on a periphery thereof; and the second thread Configured to engage the first thread.

The pressure multiplier may include a diaphragm.

The valve may include a stem having a tapered end, wherein the tapered end enters the venturi opening in the venturi nozzle in the stop position to substantially close the venturi opening.

The device may further include at least one filter detachably connected to the surrounding fluid pores.

The pressure controlled fluid may be a liquid.

In another aspect, the present invention includes a method of collecting data from a patient using a device suitable for a respirator, the method comprising: providing a source of pressure-controlled oxygen; providing a device suitable for a respirator , the apparatus includes: a venturi including a throat, a venturi nozzle and a venturi opening in the venturi nozzle through which pressure-controlled oxygen flows outwardly, wherein the venturi opening leads to the throat, and wherein the venturi opening and the throat are substantially longitudinally aligned; a surrounding fluid aperture in fluid communication with the venturi nozzle and surrounding air; a first flow a body port; a pressure multiplier in fluid communication with the fluid port, wherein the pressure multiplier includes at least one opening defined therethrough; the pressure multiplier includes an open position and a closed position relative to the at least one opening at least one cover that moves between positions; and a valve capable of causing the flow of pressure-controlled oxygen to entrain the ambient air into the throat at a start flow position and stopping the flow of pressure-controlled oxygen The flow entrains the ambient air to move along an axis of movement relative to the venturi opening in the venturi nozzle between a flow stop position in the throat; placing the fluid port in fluid communication with an airway of the patient ; in response to the patient exhaling through the fluid port causing the at least one cover to move to the closed position relative to the at least one opening and actuating the valve along the axis of movement relative to the venturi nozzle to close the venturi a nozzle; and in response to the patient inhaling through the fluid port causing the at least one cover to move to the open position relative to the at least one opening and actuating the valve along the axis of movement relative to the venturi nozzle; and wherein the movement axis of the valve is substantially longitudinally aligned with the longitudinal direction of the throat; and includes at least one of a sensor, a measuring device and a power generating device positioned between at least one of the following: the venturi nozzle and the surrounding air void; and the pressure multiplier and the fluid port; and wherein at least one of the sensor, measurement device and power generation device includes at least one of the following: a pressure sensor , oxygen sensor, carbon dioxide sensor, temperature sensor, humidity sensor, piezoelectric sensor, piezoelectric generator, spirometer measuring device, pitot measuring probe and spirometer generator; and using at least one of the sensor, measuring device and power generation device to collect raw data; using a central processing unit to package the collected raw data; using a wired or wireless communication link to package the packed raw data. transmit the data to a receiving device; receive the packaged data on the receiving device; unpack the collected raw data; quantify the unpacked raw data; format the quantified data; analyze the formatted data; distribute the Analyze the data; and use an application to display the analyzed data.

The method may include the step of coupling the central processing unit to the respirator.

Using the wireless communication link may include using at least one wireless protocol selected from Bluetooth, Wi-Fi, and Thread.

Using the wired communication link may include using at least one of a USB, serial, single wire, and parallel.

The method may include using a smart device to display the analyzed data.

The smart device may include at least one of a mobile communication device, a tablet computer, a patient interface display, a laptop computer and a desktop computer.

According to another aspect, the present invention contemplates an active filter including at least one piezoelectric element and at least one dielectric filter media, wherein the piezoelectric element generates electricity to induce an electrostatic charge in the dielectric filter media.

The use of piezoelectrics in this device will be used to power the sensors disclosed herein for data collection and data transmission. By placing a piezoelectric crystal between metal walls in the device, an electric charge is generated as mechanical pressure driven by a patient's breathing is applied to the metal. This pressure essentially creates electricity by throwing the crystal out of balance. This can generate up to 2mW of power (similar to the power stored in a lithium battery) to generate enough power for the device's sensors to collect and transmit data. For example, the limiter 72 and/or the rib 74 shown in FIG. 2A may be or be covered by piezoelectric elements that can be attributed to actuating the respirator and, in particular, The flange 38 strikes the limiter 72 (which continues to vibrate the rib 74 after the strike) to generate electricity. For example, it can be used in face masks such as N95 masks.

The power generated by the at least one piezoelectric element may be AC.

The active filter may include at least one spirometer that generates electricity to induce an electrostatic charge in the at least one dielectric filter media.

The active filter may include generating electricity to induce the at least one dielectric filter media One of the two spirometers has an electrostatic charge.

The power generated by the at least one spirometer may be DC.

The patient's inspiration through the fluid port may actuate the valve relative to the venturi nozzle to open the venturi nozzle.

The patient's exhalation into the fluid port may cause the at least one cover to move to the closed position relative to the at least one opening in the pressure multiplier.

The patient's suction through the fluid port may cause the at least one cover to move to the open position relative to the at least one opening in the pressure multiplier.

According to another aspect, the present invention contemplates an apparatus suitable for a respirator, comprising: a venturi nozzle for the flow of a pressure-controlled fluid; and a surrounding fluid aperture that is fluidly connected to the venturi nozzle. communicating; a fluid port; a pressure multiplier in fluid communication with the fluid port; and a valve movable relative to the venturi nozzle between a start flow position and a stop flow position; wherein the pressure multiplier The device is configured such that fluid forced into the fluid port relative to the venturi nozzle actuates the valve; and wherein the pressure multiplier is configured such that fluid withdrawn from the fluid port relative to the venturi nozzle Activate the valve.

According to another aspect, the present invention contemplates a device suitable for use with a ventilator that includes: a venturi including a throat, a venturi nozzle, and a pressure controlled fluid therethrough outwardly flowing. a venturi opening in the venturi nozzle, wherein the venturi opening leads to the throat, and wherein the venturi opening and the throat are substantially longitudinally aligned; a surrounding fluid pore with the venturi a nozzle in fluid communication with an ambient fluid; a fluid port; a pressure multiplier in fluid communication with the fluid port; and a valve capable of entraining the ambient fluid to the between a start flow position in the throat and a stop flow position in the throat where the flow of the pressure controlled fluid entrains the surrounding fluid with respect to the venturi The venturi opening in the mouth moves along an axis of movement; wherein the pressure multiplier is configured such that fluid forced into the fluid port actuates the valve along the axis of movement relative to the venturi nozzle to seal the venturi. a venturi nozzle; wherein the pressure multiplier is configured such that fluid withdrawn from the fluid port actuates the valve along the axis of movement relative to the venturi nozzle; wherein the axis of movement of the valve and one of the throat The longitudinal direction is substantially longitudinally aligned; and wherein the pressure multiplier is positioned between the venturi nozzle and the fluid port. Therefore, the present invention does not rely on the continuous flow of the pressure controlled fluid, which is common in known constructions. Thus, significant savings, both economic and environmental, can be achieved by actuating the valve of the present invention to regulate the flow of pressure-controlled fluid, which actually makes the overall process more efficient. The device may be particularly suitable for use in remote locations, locations in underdeveloped countries or other locations where a large and continuous supply of oxygen is unavailable or has limited opportunity to use a large and continuous supply of oxygen.

The pressure multiplier may be configured such that the (any) fluid forced into the fluid port actuates the valve to a stop-flow position relative to the venturi nozzle; and the pressure multiplier may be configured such that it automatically The (any) fluid withdrawn from the fluid port actuates the valve to an initial flow position relative to the venturi nozzle.

The pressure multiplier may be configured such that the (any) fluid forced into the fluid port actuates the valve to an initial flow position relative to the venturi nozzle; and the pressure multiplier may be configured such that from The (any) fluid withdrawn from the fluid port actuates the valve to a stop-flow position relative to the venturi nozzle. This may be considered, for example, as an inverse configuration.

The pressure multiplier may be configured such that the (any) fluid forced into the fluid port actuates the valve relative to the venturi nozzle to an active flow position between the start flow position and the stop flow position. ; and the pressure multiplier may be configured such that the (any) fluid withdrawn from the fluid port actuates the valve relative to the venturi nozzle to an active position between the start flow position and the stop flow position. Flow position. In this configuration, a fluid forced into the fluid port The action of both the valve and the withdrawal of fluid from the fluid port actuates the valve to an active flow position. This can be considered as a point anywhere between the stop flow position and the start flow position. Therefore, flow at all positions from the stop flow position to the start flow position and between the stop flow position and the start flow position can be fully controlled and/or regulated.

The device may be defined such that a pressure-controlled fluid includes oxygen, an ambient fluid includes ambient air, fluid forced into the fluid port includes air exhaled into an air port, and fluid withdrawn from the fluid port includes air from An air port draws in air.

The pressure multiplier can be positioned between the venturi nozzle and the fluid port. This positioning provides enhanced actuation of the valve.

The venturi nozzle can be positioned between the pressure multiplier and the fluid port. The inventors believe that this positioning may also provide enhanced actuation of the valve.

The venturi nozzle can be positioned between the surrounding fluid aperture and the fluid port. The inventors discovered that this positioning also provides enhanced actuation of the valve.

The apparatus may include a pressure regulator for regulating the flow of a pressure controlled fluid. It will be appreciated that at least one of a number of different pressure regulators suitable for regulating the flow of the pressure controlled fluid may be included.

More specifically, the apparatus may include a pressure regulator (for regulating the flow of the pressure controlled fluid) including: a housing formed to contain an inner bore therein; a piston that may movably disposed in the inner bore, wherein the piston includes an annular lip adjacent a first end thereof; a spring disposed in the inner bore and including a first end and a second end; an adjustment cap movably disposed in the inner bore, wherein the adjustment cap is formed to include a plurality of keyways formed therein; wherein: the first end of the spring is in physical contact with the annular lip; and the The second end of the spring is in physical contact with the adjusting cap, wherein: the adjusting cap is rotated in a first direction. The whole cap causes the adjusting cap to compress the first spring; rotating the adjusting cap in a second and opposite direction causes the adjusting cap to decompress the spring; rotating the adjusting cap in the first direction increases the output pressure of the pressure regulator ; Rotate the adjustment cap in the second direction to reduce the output pressure of the pressure regulator; the inner hole is defined by a cylindrical wall; the cylindrical wall is formed to include a first thread therein; the adjustment cap Formed to include a second thread formed on a periphery thereof; and the second thread configured to engage the first thread. Such a regulator may be particularly effective in regulating the flow of the pressure controlled fluid. The inventors have discovered that such a pressure regulator has particularly good synergy with the apparatus as defined herein. This synergy makes this pressure regulator a specific choice to produce enhanced performance of the device.

The pressure multiplier may include a diaphragm. The diaphragm can be dished to enhance its functionality.

The pressure multiplier may be bistable. This can take on an inhalation configuration and an exhalation configuration. In this manner, the pressure multiplier exhibits two steady states, which is particularly beneficial in at least some embodiments of the invention.

The pressure multiplier may be biased toward the stop flow position. In some embodiments, the pressure multiplier may be preferably biased toward the stop-flow position, and this configuration makes this possible.

The pressure multiplier may be biased toward the start flow position. Conversely or additionally, in some embodiments the pressure multiplier may be preferably biased towards the start flow position and this configuration makes this possible.

The pressure multiplier may include at least one cover.

The device can be completely mechanical. According to some embodiments, the device being entirely mechanical provides the benefits of ease of manufacture and operation.

The device may be configured to allow a mixture of pressure-controlled fluid and ambient fluid to flow to the fluid port in the initial flow position or an active flow position. For example, the ambient fluid (eg, ambient air) can become entrained by the flow of the pressure-controlled fluid (eg, oxygen) to drive flow and movement toward the fluid port.

The flow of the mixture can be modulated on the fly. Accordingly, the apparatus may control, vary and/or regulate the flow of the fluid mixture in an alternative to or in addition to regulating only the flow of the pressure-controlled fluid .

The valve may include a flange connected to the pressure multiplier.

The valve may include a stem having a tapered end, wherein the tapered end in the stop position enters a venturi opening in the venturi nozzle to substantially close the venturi opening. This configuration may operate the valve particularly efficiently with respect to the characteristics of the device as defined herein.

The rod can be connected to the pressure multiplier. This configuration makes the rod and pressure multiplier stronger during operation.

The valve may include a switch. This can be particularly effective when a binary system is desired or a binary state is desired.

The valve may include a flap valve.

The valve may include a spring loaded shuttle system.

The valve slides.

The valve can be completely mechanical.

The surrounding fluid aperture may include a fluid drain. Therefore, the surrounding fluid pores may have the dual function of allowing fluid entry and exit. Discharging fluids from the equipment can reduce contamination from used fluids within the equipment and can simplify the equipment by eliminating the need to store undischarged used fluids.

The valve may be configured to be actuated relative to the venturi nozzle while opening the fluid discharge port. This dual function improves the operating efficiency of the device.

The device may further include at least one filter detachably connected to the surrounding fluid pores. The filter is operable to filter fluid flowing into/out of the device. Using a single filter to filter both incoming and outgoing fluids can improve the operating efficiency of the equipment.

The at least one filter may include approximately 3 μm pores. For example, the pores are particularly effective at removing contaminants such as viruses and bacteria from fluids such as air.

The device may further include a ventilator or similar device that provides fluid communication between the ventilator and a patient's airway. The inventors have discovered that the ventilator used in conjunction with or forming part of the device may be particularly effective in treating respiratory conditions such as COVID-19.

The ventilator can be in fluid communication with the fluid port. For example, the fluid port may be connected directly or indirectly to the ventilator.

The fluid described above may be a liquid. Liquids can be passed through the device in a variety of applications. It will be appreciated that the device may also be used to administer liquids such as medications. For example, the device may thus serve as a modified nebulizer or vaporizer that may be used to administer a drug in the form of a liquid mist that may be inhaled into the lungs by a patient suffering from a respiratory disease or condition. However, it should be understood that any suitable liquid may be utilized using the device.

The device can be injection molded. Therefore, the equipment can be quickly reproduced in a cost-effective manner.

The device can be manufactured by additive manufacturing (eg a 3D printing process). Therefore, the equipment can be reproduced accurately and in a cost-effective manner, which makes the equipment available in less developed countries. Particularly attractive.

The device can be configured to be mobile.

The device can be configured for reuse. Because the device can be effectively cleaned, it can be suitable for reuse. This is particularly beneficial in less developed countries where availability of new equipment is not readily available.

The devices described herein can be used to control the flow of air and/or oxygen into a ventilator.

The devices described herein can be used to control the flow of purified air and/or oxygen into a ventilator.

The device described herein may be used to treat a respiratory condition.

The device described in this article may be used to treat COVID-19.

In another aspect, the present invention contemplates a method of using an apparatus suitable for a ventilator, the method comprising: providing a source of pressure-controlled fluid; providing an apparatus suitable for a ventilator, comprising: a Venturi a nozzle for receiving a flow of the pressure controlled fluid; a surrounding fluid aperture in fluid communication with the venturi nozzle; a fluid port; a pressure multiplier in fluid communication with the fluid port; and a valve , which is movable relative to the venturi nozzle between a start flow position and a stop flow position in which the pressure controlled fluid mixes with the surrounding fluid; relative to the venturi nozzle in response to fluid being forced into the fluid port. The venturi nozzle actuates the valve; and the valve is actuated relative to the venturi nozzle in response to withdrawal of fluid from the fluid port.

In another aspect, the present invention contemplates a method of using an apparatus suitable for a respirator, the method comprising: providing a source of pressure-controlled oxygen; providing an apparatus suitable for a respirator, the method comprising: a Venturi A tube including a throat; a venturi nozzle; a venturi opening in the venturi nozzle through which pressure-controlled oxygen flows outward, wherein the venturi opening is open to Toward the throat, and wherein the venturi opening and the throat are substantially longitudinally aligned; a surrounding air void in fluid communication with the venturi nozzle and surrounding air; a fluid port; and a pressure multiplier, in fluid communication with the fluid port, wherein the pressure multiplier includes at least one opening defined therethrough; the pressure multiplier includes at least one cover moveable relative to the at least one opening between an open position and a closed position ; and a valve capable of causing the flow of pressure-controlled oxygen to entrain the ambient air to a starting flow position in the throat and stopping the flow of pressure-controlled oxygen to entrain the ambient air to the throat. moving along an axis of movement between a flow stop position in the larynx relative to the venturi opening in the venturi mouth; placing the fluid port in fluid communication with an airway of the patient; responsive to the patient passing through the fluid port Exhaling causes the at least one cover to move to the closed position relative to the at least one opening and actuates the valve along an axis of movement relative to the venturi nozzle to close the venturi nozzle; and in response to the patient passing through the venturi nozzle Suction of the fluid port causes the at least one cover to move to the open position relative to the at least one opening and actuate the valve along the axis of movement relative to the venturi nozzle; and wherein the axis of movement of the valve is in contact with the throat The longitudinal direction of the parts is substantially longitudinally aligned.

The equipment in this method can be completely mechanical.

At least a portion of the valve is movable within the throat along the axis of movement.

The method may further include adjusting the pressure of the pressure controlled fluid.

The method may include the pressure-controlled fluid system pressure-controlled oxygen, and wherein the fluid system is air, the method including: connecting the device to a ventilator or similar device; connecting the ventilator to the patient and the pressure-controlled The oxygen source gas is connected; in response to the patient's inhalation, oxygen begins to flow into the respirator, the oxygen is mixed with ambient air to generate high-oxygen air and the high-oxygen air is delivered to the patient; in response to the patient's exhalation to stop the flow of oxygen into the respirator and discharge exhaled air from the respirator.

The enriched air may have at least 26% _FiO2 .

The method may comprise the pressure controlled fluid system pressure controlled filtered air, and wherein the fluid system is air, the method comprising: connecting the device to a ventilator or similar device; connecting the ventilator to the patient and the pressure Controlled filtered air source gas communication; initiating oxygen flow into the respirator in response to the patient inhaling, mixing the pressure-controlled filtered air with ambient air to produce purified air and delivering the purified air to the patient; in response to the patient exhaling, stopping the flow of oxygen into the respirator and venting exhaled air from the respirator.

The purified air may have at least 26% _FiO2 .

The method may further include walking and/or running while utilizing the device and a ventilator or similar device. For example, this may involve using the device while the user is in motion.

The method may further include initiating use of the device and a ventilator or similar device to treat the allergy.

The method may further include inducing use of the device and a ventilator or similar device to treat ARDS.

The method may further include inducing use of the device and a ventilator or similar device to treat sleep apnea.

The method may further include inducing use of the device and a ventilator or similar device to treat COPD.

The method may further include causing use of the device and a ventilator or similar device to treat COVID-19 viral infection.

The method may further include filtering the ambient air.

The method may further include filtering exhaled air from the patient.

In another aspect, the invention encompasses a pressure multiplier including a sealed end and an open end, wherein the sealed end is in fluid communication with a valve to define a gap between the sealed end and the valve a fixed volume, wherein the pressure multiplier is configured such that a change in pressure at the open end causes a change in pressure at the sealed end to actuate the valve. Such a pressure multiplier may be used particularly effectively with the apparatus defined herein. However, the pressure multiplier is considered to be inventive in its own right.

The pressure multiplier may be configured such that a negative pressure at the open end causes a decrease in pressure at the sealed end to actuate the valve.

The pressure multiplier may be configured such that a positive pressure at the open end causes an increase in pressure at the sealed end to actuate the valve.

Actuation of the valve activates a humidifier.

The actuation of the valve may produce a change in a visual indicator. The visual indicator may be, for example, a color change.

The change in the visual indicator may represent a change in pressure at one of the open ends.

The pressure change in the open end may be caused by a patient's inhalation and/or expiration. The pressure multiplier is therefore suitable for many different applications, which makes it a particularly useful accessory in one of many different fields of operation.

The nature and applicability of the invention described in this summary and the following detailed description are not intended to be all-inclusive. Many additional features and advantages will be apparent to those of ordinary skill in view of the following description. Therefore, the more important features of the invention have been summarized (in particular, broadly) so that the following detailed description of the invention may be better understood and its contribution to the art may be better understood.

2: Fluid mixer/fluid mixing equipment/breather

4: Surrounding fluid pores

6: Fluid inlet

8: Thread

10: Venturi tube

12:Channel

14: Venturi nozzle

16: Venturi opening

17:Central channel

18:Air channel

19:Larynx

20: valve

21:Pole seat

22: Rod

23: Rod hole

24:Tapered end

26:Vent ring

27: Bottom

28: Bottom

30: Curved body

32:Window

34:pore

36: Ventilation ring seat

37: Lower surface

38:Flange

39:Flange opening

40: Pressure multiplier/diaphragm

41:Import channel

42:Room

43:Import pore

44:Inner surface

54: Fluid port

56:Filter

70: cover slip

72:Limiter

74: convex strip

76:Up the wall

78: Exhalation window

80:Inner hole

82:Spring

84:end

86:Tube

88:Inflatable part

90: Room opening

92:pore

116:Lower internal thread

500: Secondary regulator

510: Shell

520: Ring lip

530: External thread

700: Secondary regulator/pressure regulator

720: Compression spring

740:Part/Area

750:Adjustment cap

752:Thread

754:Keyway

756:Keyway

758:pore

760:piston

762:Ring lip

764:Shaft parts

780: Internal thread

1550: Sensor module

1651: Sensor module

1750: Sensor module

1751: Sensor module

1853:Spirometer

1954: Spirometry

2053:Spirometer

2054:Spirometer

2155: Pitot tube

2256: Piezoelectric element

2560: Active filter

3070: Fluid flow limiter

3071:Pin

3078:Exhalation window

S1 to S12: Steps

Figure 1 is a perspective cross-sectional view of a respirator in an inhalation configuration.

Figure 2 is a side cross-sectional view of the respirator of Figure 1 in an inhalation configuration.

Figure 2A is a detailed perspective cross-sectional view of the respirator of Figure 1 in an inhalation configuration; It shows one of the diaphragms in the suction configuration.

Figure 3 - A perspective cross-sectional view of the respirator in the exhalation configuration.

Figure 3A A detailed perspective cross-sectional view of the respirator of Figure 3 in the exhalation configuration showing the exhalation window.

Figure 3B is a detailed perspective cross-sectional view of the respirator of Figure 3 in the exhalation configuration showing the cover sheet.

Figure 4 is a side cross-sectional view of the respirator of Figure 3 in an exhalation configuration.

Figure 5 is a perspective cross-sectional view of another embodiment of the respirator.

Figure 6 is a side cross-sectional view of the respirator of Figure 5.

Figure 7 is a detailed perspective cross-sectional view of a valve of the respirator of Figure 5.

Figure 8 is a detailed side cross-sectional view of a valve of the respirator of Figure 5.

Figure 9 is a perspective view of one embodiment of the primary regulator 500.

Figure 10 is a cross-sectional view of the secondary regulator 500.

FIG. 11 is a cross-sectional view of another embodiment of the primary regulator 700.

Figure 12 is an exploded view of the secondary regulator 700.

Figure 13 is a top view of an adjustment cap 750 disposed within the secondary regulator 700.

Figure 14 is a perspective view of the adjustment cap 750.

Figure 15 is a side cross-sectional view of a respirator/device according to one embodiment of the present invention having a sensor in one position.

Figure 16 is a side cross-sectional view of a respirator/device according to one embodiment of the present invention with a sensor in another position.

Figure 17 is an embodiment of the present invention having sensors in multiple locations. A side cross-sectional view of the respirator/equipment.

Figure 18 is a side cross-sectional view of a respirator/apparatus according to one embodiment of the present invention with a spirometer in one position.

Figure 19 is a side cross-sectional view of a respirator/apparatus according to one embodiment of the present invention with a spirometer in another position.

Figure 20 is a side cross-sectional view of a respirator/apparatus according to one embodiment of the present invention having a spirometer in multiple positions.

Figure 21 is a side cross-sectional view of a respirator/apparatus having a pitot tube according to one embodiment of the present invention.

Figure 22 is a side cross-sectional view of a respirator/device having a piezoelectric element according to one embodiment of the present invention.

Figure 23 is a side cross-sectional view of a respirator/device according to one embodiment of the present invention having sensors in multiple positions, a spirometer, a pitot tube, and piezoelectric elements.

Figure 24 is a perspective cross-sectional view of the respirator/apparatus of Figure 23.

Figure 25 is a side cross-sectional view of a respirator/device having an active filter according to one embodiment of the present invention.

Figure 26 is a perspective cross-sectional view of the respirator/apparatus of Figure 25.

Figure 27 is a flow chart of a method according to an embodiment of the present invention.

Figure 28 is a side cross-sectional view of a respirator/apparatus according to one embodiment of the present invention without a fluid flow restrictor.

Figure 29 is a perspective cross-sectional view of the respirator/apparatus of Figure 28.

Figure 30 is a side cross-sectional view of a respirator/apparatus according to one embodiment of the present invention with a fluid flow restrictor in an open position.

Figure 31 is a perspective cross-sectional view of the respirator/apparatus of Figure 30.

Figure 32 is a side cross-sectional view of a respirator/apparatus according to one embodiment of the present invention having a fluid flow restrictor in a restricted position.

Figure 33 is a perspective cross-sectional view of the respirator/apparatus of Figure 30.

The use of the same component symbols in different figures indicates similar or identical items.

Referring to Figures 1-2, an embodiment of a fluid mixer 2 is shown. Fluid mixer 2 may also refer to a fluid mixing device 2 or device 2 . Fluid mixer 2 can be used in a variety of applications. For example, the fluid mixer 2 may be used in medical applications, automotive applications, racing applications, and other applications. As seen in Figures 1 to 2, the fluid mixer 2 is a respirator 2. The term "respirator" as used herein encompasses any and all medical applications in which respirator 2 may be used, such as (but not limited to) continuous positive airway pressure (CPAP) machines and bi-positional positive airway pressure (BiPAP) machines. .

Returning to FIGS. 1-2 , an exemplary respirator 2 is shown in an inhalation configuration with a patient inhaling air through the respirator 2 . The respirator 2 is advantageously completely mechanical. As used herein, the term "fully mechanical" is defined to mean a mechanism that operates without electricity or electronics based on changes in gas pressure controlled by a patient's breathing. According to other embodiments, the respirator 2 uses electricity and/or electronics in whole or in part to control, power or otherwise operate. The respirator 2 includes a surrounding fluid aperture 4 which may be generally bell-shaped or which may have any other suitable shape. The openings of the surrounding fluid pores 4 may have any suitable shape (such as, but not limited to, circular, elliptical, rectilinear or polygonal) and may be bilaterally and/or radially symmetrical or asymmetrical. A surrounding fluid aperture 4 may be located at one end of the respirator 2 . The respirator 2 also includes a fluid inlet 6 positioned proximate the surrounding fluid aperture 4 . Fluid inlet 6 may be connected to a source of pressure controlled fluid, such as oxygen. As seen in Figure 1, the surrounding fluid aperture 4 and the fluid inlet 6 may be generally perpendicular to each other. straight configuration; however, the surrounding fluid aperture 4 and fluid inlet 6 may be configured relative to each other in any other suitable manner. The fluid inlet 6 may include threads 8 defined on one of its outer diameters to facilitate connection of oxygen or other pressure-controlled fluids to the respirator 2 . The pressure entering the fluid inlet 6 is advantageously slightly higher than the surrounding atmosphere. The pressure at fluid inlet 6 can be adjusted as will be described in more detail below. When used to treat a patient, the fluid inlet 6 may be the oxygen inlet through which oxygen enters the respirator 2 .

Air from the surrounding fluid pores 4 and oxygen from the fluid inlet 6 are mixed in a venturi 10 . According to some embodiments, a channel 12 is defined in the breather 2 radially external to the surrounding fluid aperture 4 and oxygen from the fluid inlet 6 travels from the fluid inlet 6 through the channel 12 to a venturi nozzle 14 and exits the venturi. Venturi opening 16 in mouth 14. The specific path, cross-section, and other details of channel 12 are not important to the present invention; rather, channel 12 may be configured in any manner as long as a sufficient amount of oxygen is delivered to venturi opening 16. An air passage 18 allows air to flow from the surrounding fluid aperture 4 to the venturi nozzle 14 . As the oxygen leaves the venturi opening 16 of the venturi nozzle 14, the oxygen flow entrains air from the throat 19 of the venturi 10 and mixes with the entrained air, which is richer in oxygen than the surrounding air. Above the Venturi nozzle 14, a central channel 17 extends upward to allow oxygen-enriched air to travel to the patient during inspiration and to allow exhaled air to travel outward from the patient during exhalation. As is generally understood in the art, a venturi is generally a short tubular section having a centrally located tapered constriction (throat 19) that causes an increase in the flow velocity of a fluid passing through it. As can be seen from Figures 1 to 2, a venturi opening 16 in the venturi nozzle 14 through which pressure-controlled oxygen (or, for example, other pressure-controlled fluid) flows outwardly leads to the throat 19, and The venturi opening 16 and the throat 19 are substantially longitudinally aligned.

A valve 20 is positioned above the venturi nozzle 14 . As used herein, directional terms such as "top," "bottom," "above," "below," and the like are used for ease of description to refer to the orientation and relative position of the components shown in the figures with respect to the page ;Respirator 2 can Used in any orientation, and such directional terms do not limit the use of respirator 2. According to some embodiments, valve 20 includes a stem 22 that may include a tapered end 24. The tapered end 24 may be tapered such that a portion of the tapered end 24 has a diameter less than the diameter of the venturi opening 16 and is accessible through the venturi opening 16 into the venturi nozzle 14 . In the open suction position shown in FIG. 1 , the tapered end 24 is spaced apart from the venturi opening 16 so that oxygen can flow out of the venturi opening 16 and entrain ambient air from the air passage 18 to the venturi 10 The throat is 19. According to other embodiments, the rod 22 need not include a tapered end 24 but may instead include an end whose diameter widens closer to the venturi nozzle 14 such that the wider end does not substantially enter the venturi. The venturi opening 16 is blocked in a closed position. A rod seat 21 may extend laterally toward the rod 22 and may include a rod aperture 23 configured to receive and guide the rod 22 in its longitudinal movement while substantially limiting lateral movement of the rod 22. Rod aperture 23 may have a shape similar to and slightly larger than rod 22. For example, if the rod 22 is generally cylindrical, the outer diameter of the rod 22 may be slightly smaller than the diameter of the rod aperture 23 so that the rod aperture 23 allows the rod 22 to slide relative to the rod aperture 23 while the rod aperture 23 also limits the lateral direction of the rod 22 sports. The valve 20 is free floating as seen in Figures 1-2. Valve 20 may optionally be biased toward the suction configuration shown in FIGS. 1-2 , for example, by a spring (not shown) or other structure or mechanism. Alternatively, valve 20 may be biased toward the expiratory configuration, for example, by a spring (not shown) or other structure or mechanism.

Rod 22 extends from tapered end 24 to a vent ring 26. The vent ring 26 may be generally cylindrical in shape, including a generally circular base 28 and a curved body 30 . One or more windows 32 may be defined by the curved body 30 . The vent ring 26 may be received by an aperture 34 in a vent ring seal 36 . Aperture 34 may have a shape similar to and slightly larger than vent ring 26 . For example, if the vent ring 26 is generally cylindrical, the outer diameter of the vent ring 26 may be slightly smaller than the diameter of the aperture 34 such that the aperture 34 of the vent ring seal 36 allows the vent ring 26 to oppose each other. Sliding in the hole 34, the hole 34 also limits the lateral movement of the vent ring 26. At least one flange 38 may extend radially outward from the vent ring 26 . The flange 38 may extend outwardly from an upper edge of the vent ring 26 or any other suitable portion of the vent ring 26 .

The flange 38 may be connected to a pressure multiplier 40 within a chamber 42; the flange 38 is advantageously secured to the pressure multiplier 40. According to some embodiments, pressure multiplier 40 is a diaphragm 40 . Diaphragm 40 extends radially between vent ring 26 and interior surface 44 of chamber 42 . The diaphragm 40 is flexible and durable and may be made of any suitable material such as rubber, latex, plastic, or one or more other materials. Because flange 38 is connected to diaphragm 40, downward movement of diaphragm 40 causes flange 38, and thus the entire valve 20, to move downward; upward movement of diaphragm 40 causes flange 38, and therefore the entire valve 20, to move upward. According to some embodiments, diaphragm 40 may be biased toward its position in the inspiratory configuration. According to other embodiments, the diaphragm 40 may be bistable such that it is stable in both its position in the inspiratory configuration and its position in the expiratory configuration. In this embodiment, the valve 20 may be in a start flow position that causes the flow of the pressure-controlled fluid (eg, pressure-controlled oxygen) to entrain ambient fluid into the throat 19 and a stop position where the flow of the pressure-controlled fluid will entrain the ambient fluid into the throat 19 . The surrounding fluid is entrained to move along a moving axis relative to the venturi opening 16 in the venturi nozzle 14 between a stop flow position in the throat 19 . For example, in one embodiment of the invention, the pressure multiplier 40 is configured such that fluid forced into the fluid port 54 actuates the valve 20 along the axis of movement relative to the venturi nozzle 14 to seal the port. Venturi nozzle 14 ; Additionally, in one embodiment of the invention, the pressure multiplier 40 is configured such that fluid withdrawn from the fluid port 54 actuates the valve along the axis of movement relative to the Venturi nozzle 14 20. In this embodiment, the axis of movement of the valve 20 is substantially longitudinally aligned with a longitudinal direction of the throat 19 . In this embodiment, at least a portion of the valve 20 is movable within the throat 19 along the axis of movement.

Referring also to Figure 2A, in the suction configuration, an inlet channel 41 and a central channel 17 fluid connection. The vent ring 26 is in an upward position relative to the venturi nozzle 14 . Therefore, the bottom 27 of the vent ring 26 can be substantially flush with the lower surface 37 of the vent ring seat 36, and the inlet aperture 43 is thus opened to allow the central channel 17 to be in fluid communication with the inlet channel 41. The flange 38 may be configured as a grid or grid (such as the concentric grid shown in Figure 2A) such that a plurality of flange openings 39 allow fluid to flow therethrough. In the suction configuration, the two sides of the diaphragm 40 are therefore in fluid communication with each other via the flange openings 39; these flange openings 39 fluidly communicate the inlet passage 41 and the fluid port 54 in the suction configuration. Thus, in the inspiratory configuration, the central channel 17, the inlet channel 41, and the fluid port 54 are in fluid communication with each other, allowing free flow of high-oxygen air from the Venturi nozzle 14 to the fluid port 54, and then to the patient.

If diaphragm 40 is bistable, diaphragm 40 may be in one of its two bistable configurations in the inspiratory configuration seen in Figure 2A. Utilizing a bistable diaphragm 40 with a stable configuration in the inspiratory configuration means that after reaching the inspiratory configuration, the patient does not need to use any respiratory force to maintain the inspiratory configuration; therefore, the respirator 2 can be used for therapy Patients with degraded respiratory capacity. If the diaphragm 40 is stable in a single configuration, that configuration may be the suction configuration shown in Figure 2A.

A pressure multiplier 40 is in fluid communication with the fluid port 54, wherein the pressure multiplier 40 includes at least one flange opening 39 defined therethrough; the pressure multiplier 40 includes an opening that is open relative to the at least one flange opening 39. At least one cover 70 moves between the position and a closed position. Referring also to FIG. 3B , one or more cover sheets 70 may be associated with flange 38 . Cover sheet 70 will be described in greater detail below with respect to Figure 3B. In the inspiratory configuration, fluid flow toward the fluid port 54 causes the cover 70 to scrape upward away from the flange 38 and its flange opening 39 allowing the free flow of enriched air to the patient through the flange opening 39 . In this embodiment, the pressure multiplier 40 is positioned between the venturi nozzle 14 and the fluid port 54 .

A limiter 72 is optionally positioned in the chamber 42 above the flange 38. According to a In some embodiments, the restrictor 72 may be a ring having a diameter that is substantially the same as the vent ring 26 , wherein the restrictor 72 is substantially coaxial with the vent ring 26 . The limiter 72 may be connected to, secured to, or integrated with one or more ribs 74 extending therefrom. One or more ribs 74 may extend upwardly from the limiter 72 ; alternatively, one or more ribs 74 may extend laterally or downwardly from the limiter 72 . The ribs 74 may be substantially rigid such that they experience substantially no bending or flexing during normal use of the respirator 2 . According to other embodiments, one or more ribs 74 may be flexible. Each rib 74 is connected to the limiter 72 at one end and to a portion of the chamber 42 at the other end. For example, one or more ribs 74 are connected to the upper wall 76 of the chamber 42 . The ribs 74 may be secured to or integrated with the upper wall 76 of the chamber 42 . For example, the upper wall 76 of the chamber 42, the ribs 74, and the limiter 72 may be injection molded, manufactured by additive manufacturing, or manufactured in any other manner as a single integrated piece. The restrictor 72 prevents the vent ring 26 and therefore the valve 20 from moving upwardly from the vent ring seat 36 and/or the stem seat 21 .

According to some embodiments, the limiter 72 has another shape than a ring. For example, the limiter 72 may be in the form of a strip, a rod, an X-shape, a square, a rectangle, an oval, or any other suitable shape. The restrictor 72 may have any shape and be placed in any position relative to the vent ring 26 to engage the vent ring 26 in the inspiratory configuration to limit its upward travel to prevent the valve 20 and/or the vent ring 26 from becoming unseating. and allows substantially unrestricted flow of fluid out of flange opening 39 .

At the upper end of chamber 42, a fluid port 54 allows inspiratory air to flow out of respirator 2 and exhaled air to flow into respirator 2. At least one filter 56 may be positioned adjacent fluid port 54 to filter both inhaled and exhaled air. Filter 56 is advantageously a 3 micron filter or other filter suitable for removing viruses, pollen and other airborne contaminants from the air. In this way, the filter 56 protects the patient from surrounding contaminants and also protects others around the respirator 2 Protection from infection in the air exhaled by the patient. The filter 56 is detachably connected to the respirator 2 such that the filter 56 can be replaced periodically. Filter 56 may be a single use filter or may be cleanable and sanitizable such that it can be cleaned and sanitized before use. Alternatively, the filter 56 may be placed adjacent the surrounding fluid pores 4 or at another location on the respirator 2 . For example, according to some embodiments, filter 56 is positioned adjacent surrounding fluid pores 4 to filter both inhaled and exhaled air. In this manner, the filter 56 protects the patient from surrounding contaminants, and also protects others around the respirator 2 from being infected by the air exhaled by the patient. Alternatively, more than one filter 56 may be utilized.

Chamber 42 may be connected via fluid port 54 to a ventilator (not shown) worn by the patient. As commonly used in the industry, the term "ventilator" refers to a device that provides breathable air to a patient or other user, for example, by providing a supply of breathable gas. However, as used herein, the term "ventilator" is specifically defined to exclude any requirement that the ventilator itself filter anything from the air provided to the patient or exhaled by the patient. According to some embodiments, the ventilator is substantially impermeable to fluids, whether gases or liquids. According to some embodiments, the ventilator may be a mask with a flexible sealing surface or other seal(s) that creates a substantially airtight seal against the patient's face. According to some embodiments, the ventilator may be a helmet or other structure that engages a part of the patient other than the face; for example, the ventilator may be a helmet that substantially seals the patient's neck and does not contact the face. According to some embodiments, all of the ventilator or a portion of the ventilator may be positioned within the patient's nose and/or mouth, and the ventilator is substantially sealed relative to the nose and/or mouth. According to some embodiments, such as those described above, the ventilator is substantially sealed relative to the patient's airway. By substantially sealing the ventilator relative to the patient's airway, small pressure changes as the patient breathes cause valve 20 to move, as will be described in more detail below. In this way, the ventilator and therefore the patient are in fluid communication with the ventilator 2 . Because the ventilator is essentially impermeable to gases, substantially all of the patient's exhaled air reaches the fluid port 54 of the ventilator 2, allowing only one A small exhalation action causes valve 20 to move. Alternatively, the ventilator and patient may be in fluid communication with respirator 2 in any other suitable manner.

Referring to FIGS. 3-4 , a respirator 2 is shown in an exhalation configuration in which a patient exhales through the respirator 2 . As will be described in more detail below, expiratory pressure from the patient causes the center of the diaphragm 40 to deflect downward. Therefore, the flange 38 connected to the diaphragm 40 moves downward. The downward movement of the flange 38 may be limited by the vent ring seat 36, and an upper surface of the vent ring seat 36 may engage a lower surface of the flange 38 to thereby prevent further downward movement of the flange 38. In the expiratory configuration, the valve 20 has moved downward relative to the venturi nozzle 14 and the tapered end 24 of the rod 22 substantially blocks the venturi opening 16 . In this manner, oxygen is substantially prevented from flowing outwardly from the fluid inlet 6 through the venturi opening 16 . The length of the rod 22 is advantageously made such that the tapered end 24 or other lower end of the rod 22 substantially blocks the venturi opening 16 when the flange 38 engages the vent ring seat 36 .

Referring also to Figure 3A, in the expiratory configuration, inlet passage 41 is no longer in substantial fluid communication with central passage 17. The vent ring 26 is in a downward position relative to the venturi nozzle 14 . Accordingly, the bottom 27 of the vent ring 26 is positioned below the lower surface 37 of the vent ring seat 36, and the inlet aperture 43 is thus closed such that the central passage 17 substantially ends in fluid communication with the inlet passage 41. An O-ring or other seal (not shown) may extend radially outward from the vent ring seat 36 to facilitate sealing the inlet aperture 43 in the exhalation configuration. Alternatively, it is not necessary to fully or partially close the inlet aperture 43 in the expiratory configuration, as exhaled air will still travel outwardly through the central passage 17, as will be described below.

In the expiratory configuration, the flange 38 has moved downward relative to its position in the inspiratory configuration and can contact the vent ring seat 36 . In this manner, the vent ring seat 36 may be used to limit downward movement of the vent ring 26. Instead, contact between the tapered end 24 of the rod 22 and the venturi nozzle 14 limits downward movement of the vent ring 26. When flange 38 is in the exhalation configuration and flange 38 contacts When the port ring 36 is seated, this contact may block at least one of the flange openings 39 . Referring also to Figure 3B, in the expiratory configuration, fluid flow from fluid port 54 causes cover 70 to push down onto flange 38 and flange opening 39 to substantially prevent free flow of fluid from the patient through flange opening 39. . In this manner, because the flange opening 39 is substantially blocked by the cover 70, the inlet aperture 43 can remain partially or even fully open, and exhaled air remains unable to substantially flow outwardly through the flange opening 39 and then outwardly through the inlet. Pore 43. In the expiratory configuration, the two sides of the barrier membrane 40 are in fluid communication with each other via the flange opening 39 . Therefore, in the exhalation configuration, inlet passage 41 and fluid port 54 are not in substantial fluid communication with each other. Cover sheet 70 may be thin, lightweight, and generally fluid impermeable. For example, cover sheet 70 may be composed of latex, rubber, silicone, or any other suitable material.

Because the flange opening 39 is closed, the patient's exhaled breath entering the fluid port 54 causes a pressure rise in the chamber 42 above the diaphragm 40 . This increase in pressure pushes the flange 38 downward to contact or approach the vent ring seat 36 to the exhalation position of the flange 38 . If diaphragm 40 is bistable, diaphragm 40 may be in one of its two bistable configurations in the exhalation configuration seen in Figure 3A. Utilizing a bistable diaphragm 40 with a stable configuration in the expiratory configuration means that after reaching the expiratory configuration, the patient does not need to use any respiratory force to maintain the expiratory configuration; therefore, the respirator 2 can be used for therapy Patients with degraded respiratory capacity. If the diaphragm 40 is stable in a single configuration, that configuration may be the exhalation configuration shown in Figure 3A.

The vent ring 26 includes one or more exhalation windows 78 defined through the sides of the vent ring 26 . One or more exhalation windows 78 may be positioned at or near the bottom 27 of the vent ring 26. As the vent ring 26 moves downward, the exhalation window 78 moves downward to below the lower surface 37 of the vent ring seat 36 . The central channel 17 is positioned below the vent ring seat 36 so that when the exhalation window 78 moves below the lower surface 37 of the vent ring seat 36, exhaled air can flow out of the chamber 42 above the diaphragm 40 and through the vent ring 26 exhalation window 78, enters the central channel 17 and then passes through the surrounding fluid pores 4 Get off the respirator 2. Thus, in the exhalation configuration, fluid port 54 and the central channel are in fluid communication with each other.

operate

The operation of the respirator 2 will now be described. Fluid port 54 of ventilator 2 is placed in fluid communication with a ventilator attached to a patient. The ventilator has a flexible sealing surface that creates a substantially airtight seal against the patient's face. The patient inhales and exhales from the ventilator into the ventilator. The ventilator is then in fluid communication with the patient's airway. In this manner, the fluid port 54 of the respirator 2 is in fluid communication with the patient's airway. According to other embodiments, fluid port 54 may be any device other than a ventilator that places fluid port 54 in fluid communication with the patient's airway; the use of a ventilator to do so is not critical to the invention.

After the patient inhales, the pressure above the diaphragm 40 decreases relative to the ambient air pressure. Therefore, the diaphragm 40 flexes upward at and near its center. Alternatively, the diaphragm 40 may be biased upward at least partially independent of the patient's inhalation. The upward movement of the diaphragm 40 causes the flange 38 to move upward because the flange 38 is connected to the diaphragm 40 . Because flange 38 is part of or connected to valve 20, upward movement of diaphragm 40 causes valve 20 to move upward. Upward movement of the valve 20 moves the stem 22 upward thereby moving the tapered end 24 of the stem out of the venturi opening 16 and away from the venturi nozzle 14 . Because the tapered end 24 of the rod 22 has been removed from the venturi opening 16, oxygen is again free to escape from the venturi opening 16. Therefore, in this embodiment, the outflow of oxygen from the venturi opening 16 is only mechanically restarted, powered by the patient's inspiration through the fluid port 54 . As long as the tapered end 24 of the rod 22 is spaced apart from the venturi opening 16, oxygen flows out of the venturi opening 16. This position of the valve 20 in which the stem 22 is spaced apart from the venturi opening 16 and fluid can flow out of the venturi opening 16 is the initial flow position of the valve 20 .

Oxygen can be supplied to fluid inlet 6 from any suitable source. According to some embodiments, the high pressure oxygen is connected to a pressure regulator, which reduces the pressure of the oxygen and outputs lower pressure oxygen to the fluid inlet 6 . In one embodiment, the pressure regulator is a ^GovReg® adjustable flow regulator from Legacy US, as described in U.S. Patent Application No. 15/488,319, filed April 14, 2017 (the " ^GovReg® document), The entire contents of this case are incorporated herein by reference. U.S. Patent Application No. 15/488,319 is a continuation-in-part of U.S. Patent Application No. 14/990,673. It was originally filed in U.S. Patent Application No. 15/ In paragraph [0001] of Application No. 488,319, U.S. Patent Application No. 15/488,319 is also expressly incorporated by reference into U.S. Patent Application No. 14/990,673. Therefore, U.S. Patent Application No. 14/990,673. The contents of U.S. Patent Application No. 14/990,673 are incorporated by reference into this application, and specifically, Figures 5A, 5B, 7A, 7B, 7C, and Figures of U.S. Patent Application No. 14/990,673. 7D and associated text. Use of the ^GovReg® Pressure Regulator allows a health care provider to set a patient's pressure and fix the pressure so that it cannot be changed without using an adjustment key to enable only health care staff It can be changed. This provides additional safety for the patient. Additionally, multiple respirators 2 can be connected to the same high-pressure oxygen source, and each respirator 2 can receive a different oxygen pressure, depending on the ^GovReg® associated with that respirator. Settings for the pressure regulator. As described in the ^GovReg® document, the pressure regulator may include a housing formed to contain a bore therein and a piston moveable within the bore, wherein the piston may contain a an annular lip adjacent one end of the piston. A spring may be disposed within the bore, wherein the spring has two ends, and an adjustment cap may be movably disposed within the bore, wherein the adjustment cap may include a keyway formed therein . A first end of the spring can be in physical contact with the annular lip, and a second end of the spring can be in physical contact with the adjustment cap. The inner bore can be defined by a cylindrical wall, and the cylindrical wall can be threaded. The adjustment cap can also Has threads so that its threads engage the threads of the cylindrical wall. Rotating the adjusting cap in one direction causes the adjusting cap to compress the spring and increase the output pressure of the pressure regulator, and rotating the adjusting cap in the opposite direction causes the adjusting cap to decompress the spring. And reduce the output pressure of the pressure regulator. The adjustment key can be detachably connected to the adjustment cap; the adjustment key can be detached from the pressure regulator. Therefore, in some embodiments, the rotation of the adjustment cap allows a health care operation Personnel sets and fixes a patient's pressure.

Referring now to FIGS. 9-14 , a pressure regulator 700 includes a housing 510 , a piston 760 movably disposed within the housing 510 , where the piston 760 is formed to include an annular lip 762 , a compression spring 720 and an adjustment cap 750 . Compression spring 720 is disposed between annular lip 520 and adjustment cap 750 .

Referring now to Figures 12-14, adjustment cap 750 is formed to include threads adjacent a first end thereof. Threads 752 are configured to engage internal threads 780 (Fig. 11).

Compression spring 720 determines the regulated output pressure in portion 740. Rotating the adjustment cap in a first direction compresses the compression spring 720 and increases the output pressure in region 740 (FIG. 11) of the regulator 700. Rotating the adjustment cap in a second and opposite direction decompresses the compression spring 720 and reduces the output pressure in region 740 (FIG. 11) of the regulator 700.

Adjustment cap 750 is further formed to include inwardly extending keyways 754 and 756 in a second end thereof. Adjustment cap 750 is further formed to include an aperture 758 extending therethrough. The shaft 764 of the piston 760 passes through the hole 758.

Oxygen travels through fluid inlet 6 and then passage 12 and then through venturi nozzle 14 and exits venturi opening 16 . The outward flow of oxygen through the venturi opening 16 entrains ambient air entering the respirator 2 through the ambient fluid pores 4 and draws ambient air into the throat 19 of the venturi 10 where the oxygen and ambient air mix. Venturi nozzle 14 may be sized and configured to produce a mixture of ambient air and oxygen that delivers a 26% fraction of inspired oxygen ( _FiO2 ) to the patient. This percentage of FiO ₂ is a recommended oxygen concentration, but other fractions may be used if necessary. The accuracy of the oxygen fraction is not critical, and the fraction can be adjusted as needed by a clinician or other health care provider. For example, _FiO2 can be adjusted by the patient from 26% to 40% as needed; after adjusting _FiO2 to 40%, if the patient requires additional oxygen, the patient can then be removed from ventilator 2, intubated and then placed on One currently known respirator.

The enriched air travels upward through the central channel 17 to the inlet aperture 43. In the suction configuration, the inlet passage 41 is in fluid communication with the central passage 17 . As described above, in the inspiratory configuration, the vent ring 26 is in an upward position relative to the venturi nozzle 14 . In the inspiratory configuration, the reduced pressure in the chamber 42 above the diaphragm 40 caused by the patient inhaling through the fluid port 54 causes the diaphragm 40 to move upward. Inhalation removes gas from the chamber 42 above the diaphragm 40 to reduce the pressure and actuate the valve 20 relative to the venturi nozzle 14 . The flange 38 may contact the limiter 72 such that the flange 38 does not move higher than the limiter 72 allows. The upward movement of the diaphragm 40 causes the flange 38 attached to the diaphragm 40 to move upward. The upward movement of the flange 38 causes the valve 20 of which the flange 38 is a part to also move upward. This upward movement of valve 20 moves stem 22 away from venturi nozzle 14 thereby unblocking venturi opening 16 and allowing gas to flow outward therefrom. Diaphragm 40 is an example of a pressure multiplier 40 because the combination of the surface area of diaphragm 40 and flange opening 39 allows a small differential change in pressure at fluid port 54 to actuate valve 20 between a closed state and an open state. .

As described above, in the suction configuration, the inlet aperture 43 is open to fluidly communicate the central channel 17 with the inlet channel 41, and the two sides of the diaphragm 40 are therefore in fluid communication with each other via the flange opening 39; therefore, the flanges Rim opening 39 provides fluid communication between inlet passage 41 and fluid port 54 in the suction configuration. Thus, in the inspiratory configuration, the central channel 17, the inlet channel 41, and the fluid port 54 are in fluid communication with each other, allowing free flow of high-oxygen air from the Venturi nozzle 14 to the fluid port 54, and then to the patient.

The patient breathes in normally or as normally as possible. Respirator Series 2 - a simple single mode respirator An inhaler that does not deliver a specific limited or preselected volume or flow rate of air to the patient; instead, it delivers air at a volume and flow rate that is completely controlled by the patient's own inhalation. Furthermore, the respirator 2 delivers high-oxygen air to the patient only during and immediately after the patient's inhalation. Unlike continuous positive airway pressure (CPAP) or positive end-expiratory pressure (PEEP) ventilation, high-oxygen air is supplied to the patient only during inspiration. In this manner, the respirator 2 does not exert pressure on the patient's nose or mouth when the patient attempts to exhale, and does not waste oxygen by applying oxygen to the patient's nose or mouth when the patient actively exhales.

After inhaling, the patient then exhales. After the patient exhales, the pressure above the diaphragm 40 increases relative to the ambient air pressure. Referring also to Figure 3B, in the exhalation configuration, fluid flow from fluid port 54 into chamber 42 causes cover 70 to push down on flange 38 and flange opening 39 to substantially prevent free flow of fluid from the patient through the flange. Edge opening 39. In this manner, because the flange opening 39 is substantially blocked by the cover 70, the inlet aperture 43 can remain partially or even fully open, and exhaled air is still unable to substantially flow outwardly through the flange opening 39 and then outwardly through the inlet. Pore 43. In the expiratory configuration, the two sides of the barrier membrane 40 are in fluid communication with each other via the flange opening 39 . Therefore, in the exhalation configuration, inlet passage 41 and fluid port 54 are not in substantial fluid communication with each other.

Because the flange opening 39 is closed, the patient's exhaled breath entering the fluid port 54 causes a pressure rise in the chamber 42 above the diaphragm 40 . That is, exhalation forces gas into the chamber 42 above the diaphragm 40 to increase pressure and actuate the valve 20 relative to the venturi nozzle 14 . This increase in pressure pushes the flange 38 downward to contact or approach the vent ring seat 36 to the exhalation position of the flange 38 . Because flange 38 is part of or connected to valve 20, this downward movement of diaphragm 40 causes valve 20 to move downward. This downward movement of the valve 20 moves the rod 22 downward thereby moving the tapered end 24 of the rod toward the venturi nozzle 14 and into the venturi opening 16 . Because the tapered end 24 of the rod 22 has moved into the venturi opening 16, so oxygen is substantially restricted from escaping from the venturi opening 16. Therefore, the outflow of oxygen from the venturi opening 16 is only mechanically stopped, powered by the patient's exhalation through the fluid port 54 . As long as the tapered end 24 of the rod 22 is plugged into the venturi opening 16, the escape of oxygen from the venturi opening 16 is substantially restricted. This position of the valve 20 in which the stem 22 plugs the venturi opening 16 and substantially restricts the flow of fluid from the venturi opening 16 is the stop-flow position of the valve 20 .

As the flange 38 and the vent ring 26 move downward, the exhalation window 78 moves downward to below the lower surface 37 of the vent ring seat 36 . The central channel 17 is positioned below the vent ring seat 36 so that when the exhalation window 78 moves below the lower surface 37 of the vent ring seat 36, exhaled air can flow out of the chamber 42 above the diaphragm 40 and through the vent ring 26 The exhalation window 78 enters the central channel 17 and then exits the respirator 2 through the surrounding fluid pores 4. Thus, in the exhalation configuration, fluid port 54 and the central channel are in fluid communication with each other. The exhaled gas then travels through the central channel 17 and exits the respirator 2 through the surrounding fluid pores 4 . When the patient then inhales again, the cycle is repeated again.

According to some embodiments, because the respirator 2 does not require electricity to operate, its form factor can be quite small, making the respirator 2 portable. The respirator 2 can be carried on the user's back like a backpack with one or several straps; it can be hung on the shoulder like a wallet with a strap; it can be like a suitcase with wheels and can be pulled by a user. You may be able to carry it behind your back in other ways. The portability of the respirator 2 also allows the user to take the respirator 2 home. Respirator 2 use at home may be advantageous for patients who have been diagnosed with COVID-19 or other respiratory diseases but whose symptoms have not progressed to ARDS to a severity such that they require intubation and ventilation. In this way, during a pandemic, such as the 2020 COVID-19 epidemic, patients infected with a virus that causes respiratory problems can be treated safely at home without consuming the medication needed to treat patients who are significantly more seriously ill and close to death. Hospital beds and other hospital resources.

Because the respirator 2 is small, portable, non-invasive and provides only one user with high-oxygen air with a higher oxygen concentration, the respirator 2 can be used in other applications. As an example, respirator 2 may be used to treat asthma and/or seasonal allergies. A user wears a respirator as described above, and the respirator 2 operates as described above; a user uses it as a portable device. The increased oxygen concentration delivered by the respirator 2 may benefit asthmatics, and the filter(s) 56 may be used to remove pollen and other allergens from the air before it can be inhaled by the user, thereby ameliorating the effects of seasonal allergies. Symptoms experienced by users of the disease. As another example, in extremely polluted cities, the air may be unhealthy to breathe. By using the respirator 2 as a portable device, clean oxygen is delivered to the user at a concentration higher than the ambient concentration, and the filter(s) 56 can be used to remove it from the ambient air before being inhaled by the user. particles and/or other contaminants.

The respirator 2 described above with respect to Figures 1 to 4 may be particularly useful in treating patients infected with the COVID-19 virus, especially before they develop ARDS. It is believed that treating these patients with a respirator 2 may prevent some of these patients from developing ARDS. It is expected that Respirator 2 will be classified by the FDA as a Class II medical device and will require FDA approval for use in treating patients. Although the regulatory path for Respirator 2 to be approved by the FDA as of the filing date of this invention is unknown, it is expected that in order to be used as a medical device, Respirator 2 will require an Investigational Device Exemption (IDE) and an Emergency Use Authorization (EUA). and at least one of a pre-market approval (PMA). It is believed that the independent claim as filed covers embodiments of a respirator 2 that would be subject to FDA approval.

However, the respirator 2 is not limited to treating patients infected with the COVID-19 virus; the respirator 2 can be used to treat patients suffering from other ailments. Furthermore, the respirator 2 may be used in areas other than health care where control of fluid flow is required, and in such areas it is not necessary to use it in conjunction with a human being. Furthermore, respirator 2 is described above as having components in fluid communication with each other and with one or more external accessories (eg, a ventilator). When respirator 2 is used to treat a patient When the fluid is connected, the flow system is a gas. However, when the respirator 2 is used in other applications, the fluid may be a liquid or a mixture of liquid and gas.

While the embodiments of the present invention described above are intended to facilitate the treatment of respiratory conditions associated with COVID-19, it should be understood that the fluid mixer 2 has various other uses and applications in other fields, including (but not limited to) the following: By. As an example, in Formula One and other racing applications, the fluid mixer 2 can be used to pre-spin a turbocharger by detecting pressure changes, actuating cam timing changes based on pressure, and actuating fuel/fuel based on pressure. Opening of the air and exhaust ports activates pneumatic downpressure adjustments based on pressure conditions at a sample site, which activates fuel system pressure adjustments and regulates fluid temperature. As another example, in standard automotive use, the fluid mixer 2 may be used to actuate turbocharger pre-rotation, actuate cam timing changes, actuate opening of fuel/air and exhaust ports based on pressure, actuate fuel System pressure adjustment and fluid temperature regulation. As another example, in indoor agricultural applications, fluid mixer 2 may be used to actuate gas mixing based on pressure and/or actuate a pressure communication system. In such applications, the fluid flowing through fluid mixer 2 may be a liquid, a gas, or both.

Referring also to Figures 5 to 8, another embodiment of the fluid mixer 2 is shown. This embodiment can be described as a "reverse configuration". This embodiment may be used in automotive or racing applications, but the fluid mixer 2 of Figures 5 to 8 is not limited to use in these applications. Any embodiment may be used with liquids, gases, or both as fluids. As seen in Figures 5 to 8, the valve 20 is in an initial flow position where fluid can enter the fluid mixer 2 through the fluid inlet 6. Valve 20 may include a tapered end 24 or other suitably shaped end received within an internal bore 80 . A spring 82 may also be received in the inner bore 80 . One end of the spring 82 can engage one end of the inner bore 80 and the other end of the spring 82 can engage one end of the valve 20 . The other end 84 of the valve 20 may be substantially cylindrical or have any other suitable shape. End 84 of valve 20 is received in a tube 86 through which fluid can flow. Inner hole 80 series solid is substantially hollow such that fluid flows from the fluid inlet 6 through the inner bore 80 and then into the one or more channels 12 when the valve 20 is in the start flow position. As described with respect to previous embodiments, fluid flows from one or more channels 12 through the venturi opening 16 in the venturi nozzle 14 .

In this embodiment, pressure multiplier 40 is substantially sealed to chamber 42 to form a sealed plenum 88 . Unlike previous embodiments, fluid does not substantially traverse pressure multiplier 40 . As fluid flows into the fluid mixer 2 through the fluid port 54, the fluid flows through the central channel 17 towards the surrounding fluid apertures 4. The chamber 42 opens into the central passage 17 through a chamber opening 90 . Chamber opening 90 may be of any suitable shape and size. Chamber opening 90 allows fluid communication between chamber 42 and central channel 17 . As fluid is forced through fluid port 54 into central channel 17, the pressure in central channel 17 increases. The pressure in chamber 42 on the side of pressure multiplier 40 opposite plenum 88 also increases due to fluid communication through chamber opening 90. Because pressure multiplier 40 is substantially sealed to chamber 42 and fluid is substantially unable to traverse pressure multiplier 40 , the pressure on pressure multiplier 40 increases causing pressure multiplier 40 to move and thereby reduce the volume of plenum 88 to The pressure in the plenum 88 is also increased. This increased pressure in the plenum 88 is transmitted through tube 86 to end 84 of valve 20 . The pressure drives end 84 of valve 20 toward spring 82 in bore 80 to open valve 20 to the initial flow position. In the start flow position, the tapered end 24 of the valve 20 or other shaped end of the valve 20 moves away from the aperture 92 to allow fluid to flow through the aperture 92 into the inner bore 80 . The volume of the plenum 88 and the volume of the tube 86 can remain substantially constant during this procedure. This is because the end 84 of the valve 20 in the inner bore 80 is moveable such that any temporary pressure increase and volume decrease in the plenum 88 can be substantially matched by the movement of the end 84 of the valve 20 . In this manner, a substantially fixed volume may be defined on one side of the pressure multiplier 40.

As fluid flows into the fluid mixer 2 through the surrounding fluid pores 4, the fluid flows through the central channel 17 towards the fluid port 54. As fluid withdraws through fluid port 54, the The pressure in the central channel 17 decreases. The pressure in the chamber 42 on the side of the pressure multiplier 40 opposite the plenum 88 is also reduced due to fluid communication through the chamber opening 90 . Because pressure multiplier 40 is substantially sealed to chamber 42 and fluid is substantially unable to traverse pressure multiplier 40 , the pressure on pressure multiplier 40 decreases causing pressure multiplier 40 to move and thereby reduce the volume of plenum 88 to The pressure in the plenum 88 is also reduced. The reduced pressure in the plenum 88 is transmitted through tube 86 to end 84 of valve 20 . The pressure applied to the end 84 of the valve 20 in the inner bore 80 decreases allowing the spring 82 to push the end 84 of the valve 20 further into the tube 86 . Spring 82 may be a compression spring that biases valve 20 toward the stop-flow position; movement of valve 20 toward tube 86 closes valve 20 to the stop-flow position. In the stop-flow position, the tapered end 24 of the valve 20 or other shaped end of the valve 20 moves toward the aperture 92 and substantially blocks the aperture 92 to substantially prevent fluid flow through the aperture 92 into the inner bore 80 . According to some embodiments, the start flow position of valve 20 is also an active flow position, which allows fluid to flow while the valve is in the start flow position. Alternatively, the valve 20 may be positioned in a different active flow position between the start flow position and the stop flow position; this active flow position may be at the level of a force forcing fluid into or out of the fluid port 54 or duration determination.

Referring now to Figure 15, a side cross-sectional view of a respirator/apparatus 2 according to one embodiment of the present invention is shown. Respirator/Device 2 is the respirator/device described herein, but with a sensor module 1550 positioned between the pressure multiplier and the fluid port. Sensor module 1550 may include any sensor described herein, such as a pressure sensor, oxygen sensor, carbon dioxide sensor, temperature sensor, humidity sensor, etc. In this embodiment, the sensor module 1550 also includes a central processing unit.

Referring now to Figure 16, a side cross-sectional view of a respirator/apparatus 2 according to one embodiment of the present invention is shown. Respirator/Device 2 is the respirator/device described herein, but with a sensor module 1651 positioned between the venturi nozzle and the surrounding air void. Sensor module 1651 may include any sensor described herein, such as a pressure sensor, oxygen sensor, carbon dioxide sensor, temperature sensor, humidity sensor, etc.

Referring now to Figure 17, a side cross-sectional view of a respirator/apparatus 2 according to one embodiment of the present invention is shown. Respirator/Device 2 is the respirator/device described herein, but with a sensor module 1750 positioned between the pressure multiplier and the fluid port, and a sensor module 1750 positioned between the venturi nozzle and the surrounding air void. A sensor module 1751. Sensor modules 1750/1751 may include any of the sensors described herein, such as pressure sensors, oxygen sensors, carbon dioxide sensors, temperature sensors, humidity sensors, etc.

Referring now to Figure 18, a side cross-sectional view of a respirator/apparatus 2 according to one embodiment of the present invention is shown. Respirator/Device 2 is the respirator/device described herein, but with a spirometer 1853 positioned between the pressure multiplier and the fluid port.

Referring now to Figure 19, a side cross-sectional view of a respirator/apparatus 2 according to one embodiment of the present invention is shown. Respirator/Device 2 is the respirator/device described herein, but with a spirometer 1954 positioned between the Venturi nozzle and the surrounding air void.

Figure 20 is a side cross-sectional view of a respirator/apparatus according to one embodiment of the present invention having multiple spirometers 2053 and 2054 in multiple positions. That is, there is a spirometer 2053 positioned between the pressure multiplier and the fluid port and a spirometer 2054 positioned between the venturi nozzle and the surrounding air void.

Figure 21 is a side cross-sectional view of a respirator/device 2 according to one embodiment of the present invention with a pitot tube 2155 between the pressure multiplier and the fluid port.

Figure 22 is a side cross-sectional view of a respirator/device 2 according to one embodiment of the present invention having a piezoelectric element 2256 at the limiter 72.

Figure 23 is a diagram with sensors in multiple locations, a spirometer, a pitot tube, and Piezoelectric element A side cross-sectional view of a respirator/apparatus 2 according to an embodiment of the present invention, the same element numbers indicating the same features shown in the earlier embodiments.

Figure 24 is a perspective cross-sectional view of the respirator/apparatus 2 of Figure 23.

Figure 25 is a side cross-sectional view of a respirator/device 2 according to one embodiment of the present invention having an active filter 2560 positioned adjacent the surrounding fluid aperture.

Figure 26 is a perspective cross-sectional view of the respirator/apparatus of Figure 25.

Figure 27 is a flow chart of a method according to an embodiment of the present invention. Steps S1 to S12 correspond to the steps defined herein.

Figure 28 is a side cross-sectional view of a respirator/apparatus according to one embodiment of the present invention without a fluid flow restrictor.

Figure 29 is a perspective cross-sectional view of the respirator/apparatus of Figure 28.

Figure 30 is a side cross-sectional view of a respirator/device 2 according to one embodiment of the present invention with a fluid flow restrictor 3070 in an open position. The respirator 2 includes an exhalation window 3078 for allowing fluid to exit the respirator 2 during exhalation and for at least selectively partially closing the expiration window 3078 to set a fluid flow limit for the patient's positive end-expiratory pressure (PEEP). Device 3070. The fluid flow restrictor 3070 is in the shape of a collar and is positioned adjacent the vent ring and is held in place by a pair of pins 3071 such that it can be selectively adjusted linearly to select the collar to block the expiratory window. 3078 degree.

Figure 31 is a perspective cross-sectional view of the respirator/apparatus of Figure 30.

Figure 32 is a side cross-sectional view of a respirator/apparatus according to one embodiment of the present invention having a fluid flow restrictor in a restricted position.

Figure 33 is a perspective cross-sectional view of the respirator/device of Figure 30 in the open position.

Items

It is to be understood that the following clauses form part of the specification and the disclosure of the invention as defined herein. More specifically, the invention may be defined by a combination of features as will be described in detail below, and these may be used to modify the combination of features within the patentable scope of the present application.

1. A venturi device, comprising: a venturi nozzle for the flow of a pressure-controlled fluid; a surrounding fluid pore in fluid communication with the venturi nozzle; a fluid port; a pressure multiplier, in fluid communication with the fluid port; and a valve movable relative to the venturi nozzle between a start flow position and a stop flow position; wherein the pressure multiplier is configured to be forced into the fluid port The fluid actuates the valve relative to the venturi nozzle; and wherein the pressure multiplier is configured such that fluid withdrawn from the fluid port actuates the valve relative to the venturi nozzle.

2. An apparatus suitable for use in a ventilator, comprising: a venturi nozzle for the flow of a pressure-controlled fluid; a surrounding fluid aperture in fluid communication with the venturi nozzle; a fluid port; a a pressure multiplier in fluid communication with the fluid port; and a valve movable relative to the venturi nozzle between a start flow position and a stop flow position; wherein the pressure multiplier is configured such that fluid forced into the fluid port actuates the valve relative to the venturi; and wherein the pressure multiplier is configured such that fluid withdrawn from the fluid port actuates the valve relative to the venturi nozzle; and wherein the pressure multiplier is configured such that fluid withdrawn from the fluid port actuates the valve relative to the venturi nozzle; A venturi nozzle actuates the valve.

3. The apparatus of clause 1 or clause 2, wherein the pressure multiplier is configured such that fluid forced into the fluid port actuates the valve to a stop-flow position relative to the venturi nozzle; and wherein The pressure multiplier is configured such that fluid withdrawn from the fluid port actuates the valve to an initial flow position relative to the venturi nozzle.

4. The apparatus of clause 1 or clause 2, wherein the pressure multiplier is configured such that fluid forced into the fluid port actuates the valve to an initial flow position relative to the venturi nozzle; and wherein The pressure multiplier is configured so that fluid withdrawn from the fluid port actuates the valve to a stop-flow position relative to the venturi nozzle.

5. The apparatus of clause 1 or clause 2, wherein the pressure multiplier is configured such that fluid forced into the fluid port actuates the valve to the start flow position and the stop relative to the venturi nozzle an active flow position between flow positions; and wherein the pressure multiplier is configured such that fluid withdrawn from the fluid port actuates the valve to the start flow position and the stop flow position relative to the venturi nozzle an active flow position between.

6. A device as in any one of clauses 1 to 5, wherein a pressure controlled fluid contains oxygen, a surrounding fluid contains ambient air, and the fluid forced into the fluid port contains air exhaled into an air port, and Fluid withdrawn from the fluid port includes air drawn in from an air port.

7. The apparatus of any one of clauses 1 to 5, wherein the pressure multiplier is positioned between the venturi nozzle and the fluid port.

8. The apparatus of any one of clauses 1 to 5, wherein the venturi nozzle is positioned between the pressure multiplier and the fluid port.

9. The apparatus of any one of clauses 1 to 5, wherein the venturi nozzle is positioned between the surrounding fluid aperture and the fluid port.

10. The apparatus of any one of clauses 1 to 9, comprising a pressure regulator for regulating the flow of a pressure controlled fluid, the pressure regulator comprising: a housing formed to contain therein an inner bore; a piston movably disposed within the inner bore, wherein the piston includes an annular lip adjacent a first end thereof; a spring disposed within the inner bore and including a first one end and a second end; an adjustment cap movably disposed in the inner hole, wherein the adjustment cap is formed to include a plurality of keyways formed therein; wherein: the first end of the spring and The annular lip is in physical contact; and the second end of the spring is in physical contact with the adjustment cap, wherein: rotating the adjustment cap in a first direction causes the adjustment cap to compress the first spring; in a second and opposite direction Rotating the adjusting cap causes the adjusting cap to decompress the spring; rotating the adjusting cap along the first direction increases the output pressure of the pressure regulator; rotating the adjusting cap along the second direction decreases the output of the pressure regulator pressure; the inner bore is defined by a cylindrical wall; the cylindrical wall is formed to contain the first thread therein; The adjustment cap is formed to include a second thread formed on a periphery thereof; the second thread is configured to engage the first thread.

11. The apparatus of any one of clauses 1 to 10, wherein the pressure multiplier includes a diaphragm.

12. Equipment according to any one of clauses 1 to 11, wherein the pressure multiplier is bistable.

13. The apparatus of any one of clauses 3 to 12, wherein the pressure multiplier is biased towards the stop flow position.

14. The apparatus of any one of clauses 3 to 12, wherein the pressure multiplier is biased towards the start flow position.

15. The device according to any one of clauses 1 to 10, wherein the pressure multiplier includes at least one cover sheet.

16. Equipment as in any one of clauses 1 to 15, wherein the equipment is completely mechanical.

17. The apparatus of any one of clauses 3 to 16, wherein in the start flow position or an active flow position, a mixture of pressure controlled fluid and ambient fluid is allowed to flow to the fluid port.

18. The equipment of clause 17, wherein the flow of the mixture is modulated in real time.

19. The apparatus of any one of clauses 1 to 18, wherein the valve includes a flange connected to the pressure multiplier.

20. Apparatus as in any one of clauses 1 to 18, wherein the valve comprises a rod having a tapered end, wherein the tapered end enters a venturi in the venturi nozzle in the stop position Opening to substantially close the venturi opening.

21. The apparatus of clause 20, wherein the rod is connected to the pressure multiplier.

22. Equipment according to any one of clauses 1 to 18, wherein the valve includes a switch.

23. Equipment as in any one of clauses 1 to 18, wherein the valve includes a flap valve.

24. The apparatus of any one of clauses 1 to 18, wherein the valve includes a spring-loaded shuttle system.

25. Equipment as in any one of clauses 1 to 18, wherein the valve is slidable.

26. Equipment as in any one of clauses 1 to 25, wherein the valve is entirely mechanical.

27. The apparatus of any one of clauses 1 to 26, wherein the surrounding fluid aperture includes a fluid drain.

28. The apparatus of clause 27, wherein the valve is configured to be actuated relative to the venturi nozzle while opening the fluid discharge port.

29. The apparatus of any one of clauses 1 to 28, further comprising at least one filter detachably connected to the surrounding fluid pores.

30. The apparatus of clause 29, wherein the at least one filter contains pores of approximately 3 μm.

31. The equipment according to any one of items 1 to 30, further comprising a ventilator.

32. The apparatus of clause 31, wherein the ventilator is in fluid communication with the fluid port.

33. The device according to any one of clauses 1 to 32, wherein the fluid system is a liquid.

34. Equipment as in any one of items 1 to 33, wherein the equipment is injected into type.

35. The equipment according to any one of items 1 to 33, wherein the equipment is 3D printed.

36. Equipment according to any one of clauses 1 to 35, wherein the equipment is configured to act.

37. Equipment according to any one of clauses 1 to 36, wherein the equipment is configured for reuse.

38. Equipment according to any one of items 1 to 37 used to control the flow of air and/or oxygen to a ventilator.

39. Equipment according to any one of items 1 to 38 used to control the flow of purified air and/or oxygen into a ventilator.

40. Equipment according to any one of items 1 to 39, used to treat a respiratory condition.

41. The device according to any one of items 1 to 40, which is used to treat COVID-19.

42. A method of using an apparatus suitable for a ventilator, the method comprising: providing a source of pressure controlled fluid; providing an apparatus suitable for a ventilator, the method comprising: a venturi nozzle for receiving the a flow of pressure-controlled fluid; a surrounding fluid pore in fluid communication with the venturi nozzle; a fluid port; a pressure multiplier in fluid communication with the fluid port; and a valve movable relative to the venturi nozzle between a start flow position and a stop flow position in which the pressure controlled fluid mixes with the surrounding fluid; in response to fluid being forced into the fluid port; The venturi nozzle actuates the valve; and the valve is actuated relative to the venturi nozzle in response to withdrawal of fluid from the fluid port.

43. The method of clause 42, wherein the apparatus is entirely mechanical.

44. The method of clause 42 or clause 43, further comprising adjusting the pressure of the pressure controlled fluid.

45. The method of any one of clauses 42 to 44, wherein the method is for treating a living patient using the device to inhale and exhale air, wherein the pressure-controlled fluid system pressure-controlled oxygen, and wherein the pressure-controlled fluid system is pressure-controlled oxygen Fluid air, the method comprising: connecting the device to a ventilator; placing the ventilator in gaseous communication with the patient and the pressure-controlled oxygen source; and initiating the flow of oxygen into the ventilator in response to the patient inhaling. , mixing the oxygen with ambient air to create high-oxygen air and delivering the high-oxygen air to the patient; and stopping the flow of oxygen into the ventilator and exhausting exhaled air from the ventilator in response to the patient exhaling.

46. The method of clause 45, wherein the enriched air has at least 26% _FiO2 .

47. The method of any one of clauses 42 to 44, wherein the method is for treating a living patient using the device to inhale and exhale air, wherein the pressure-controlled fluid system is pressure-controlled filtered air, and wherein the fluid system is air, and the method includes: connecting the device to a ventilator; placing the ventilator in gas communication with the patient and the pressure-controlled filtered air source; initiating the flow of oxygen into the ventilator in response to the patient's inhalation, mixing the pressure-controlled filtered air with ambient air to produce purified air and delivering the purified air to the patient; in response to the patient's exhalation to stop the flow of oxygen into the ventilator and discharge exhaled air from the ventilator.

48. The method of clause 47, wherein the purified air has at least 26% FiO ₂ .

49. The method of any one of clauses 42 to 48, further comprising walking and/or running while using the device and a ventilator.

50. The method of any one of clauses 42 to 49, further comprising inducing use of the device and ventilator to treat allergies.

51. The method of any one of clauses 42 to 49, further comprising inducing use of the device and ventilator to treat ARDS.

52. The method of any one of clauses 42 to 49, further comprising inducing use of the device and ventilator to treat sleep apnea.

53. The method of any one of clauses 42 to 49, further comprising inducing use of the device and ventilator to treat COPD.

54. The method of any one of clauses 42 to 49, further comprising initiating the use of the device and ventilator to treat infection with the COVID-19 virus.

55. The method of any one of clauses 42 to 54, further comprising filtering the ambient air.

56. The method of any one of clauses 42 to 55, further comprising filtering exhaled air from the patient.

57. A pressure multiplier comprising a sealed end and an open end, wherein the sealed end is in fluid communication with a valve to define a fixed volume between the sealed end and the valve, and wherein the pressure multiplier is configured such that the A change in pressure at the open end causes a change in pressure at the sealed end to actuate the valve.

58. The pressure multiplier of clause 57 configured so that a negative pressure at the open end causes a reduction in pressure at the sealed end to actuate the valve.

59. The pressure multiplier of clause 57 configured so that a positive pressure at the open end causes an increase in pressure at the sealed end to actuate the valve.

60. The pressure multiplier of any one of clauses 57 to 59, wherein the actuation of the valve activates a humidifier.

61. The pressure multiplier of any one of clauses 57 to 59, wherein the actuation of the valve produces a change in a visual indicator.

62. The pressure multiplier of clause 61, wherein the change in the visual indicator represents a change in pressure at the open end.

63. The pressure multiplier of clause 62, wherein the change in pressure at the open end is caused by inhalation and/or expiration of a patient.

As used in this disclosure (both in the description and as claimed) and as commonly used in the art, the terms "substantially," "substantially," and similar approximations indicate that the terms are used to account for manufacturing tolerances, manufacturing variations, and manufacturing inaccuracies. Precision is an inevitable part of making any mechanism or structure in the physical world.

Although the present invention has been described in detail, it will be understood by those skilled in the art that various changes and modifications can be made and equivalents employed without departing from the invention. It should be understood that the present invention is not limited to the details of construction, arrangement of components and/or methods set forth in the above description or illustrated in the drawings. Law. The descriptions in the Abstract and any general descriptions of the present invention are for illustration only; they should not and cannot be construed as limiting the scope of the patent application. Furthermore, the figures are illustrative only and not limiting. Topic titles and subtitles are for the convenience of readers only. They should not and cannot be construed as having any substantive meaning, meaning or interpretation, and should not and cannot be taken to indicate that all information relevant to any particular topic is to be found under any particular heading or sub-heading or is restricted to Any specific heading or sub-heading. The purpose of this abstract is to enable the U.S. Patent and Trademark Office and readers unfamiliar with patent or legal terminology or wording to quickly determine the nature and essence of the technical disclosure of this application through extensive reading. The Abstract is not intended to define the invention nor to limit the scope of the invention. The purpose of the provisions of this invention is to provide support for the patentability of any subsequent foreign patent application claiming priority to this invention. The terms are not intended to define the invention, nor are they intended to limit the scope of the invention. Accordingly, the present invention is limited only by the scope of the following claims and their legal equivalents.

2: Fluid mixer/fluid mixing equipment/breather

4: Surrounding fluid pores

6: Fluid inlet

8: Thread

10: Venturi tube

12:Channel

20: valve

22: Rod

42:Room

54: Fluid port

74: convex strip

Claims (25)

A respirator connectable to the airway of a living patient, comprising: a venturi including a throat; a venturi nozzle; a venturi opening in the venturi nozzle through which pressure-controlled oxygen passes external flow, wherein the venturi opening leads to the throat, and wherein the venturi opening and the throat are substantially longitudinally aligned; a surrounding air void in fluid communication with the venturi nozzle and surrounding air; a fluid port in fluid communication with the airway of the living patient; a pressure multiplier in fluid communication with the fluid port, wherein the pressure multiplier includes at least one flange opening defined therethrough; the pressure multiplier includes at least one cover movable relative to the at least one flange opening between an open position and a closed position; and a valve capable of causing the flow of pressure-controlled oxygen to entrain the ambient air to the Between a start flow position in the throat and a cessation of the flow of pressure-controlled oxygen entraining the ambient air to a stop flow position in the throat relative to an edge along the venturi opening in the venturi nozzle The axis of movement moves; wherein the pressure multiplier is configured such that the living patient exhales into the fluid port actuating the valve along the axis of movement relative to the venturi nozzle to close the venturi nozzle; wherein the pressure multiplier The device is configured such that inhalation by the living patient through the fluid port actuates the valve along the axis of movement relative to the venturi nozzle; wherein the axis of movement of the valve is substantially longitudinally aligned with a longitudinal direction of the throat ; and includes at least one of a sensor, a measuring device and a power generation device, which is located at the following Between at least one of: the venturi nozzle and the surrounding air void; and the pressure multiplier and the fluid port; and wherein at least one of the sensor, measurement device and power generation device includes at least one of the following : A pressure sensor, oxygen sensor, carbon dioxide sensor, temperature sensor, humidity sensor, piezoelectric sensor, piezoelectric generator, spirometry measuring device, pitot measuring probe and spirometer generator. The respirator of claim 1, wherein at least one of the sensor, the measuring device and the power generating device is positioned between the venturi nozzle and the surrounding air void, and the sensor, measuring device and power generating device At least one of the devices is positioned between the pressure multiplier and the fluid port. The respirator of claim 1, wherein in order to collect differential data, at least one of the sensor, the measuring device and the power generating device is positioned between the venturi nozzle and the surrounding air void, and one of the same type At least one of a sensor, a measurement device, and a power generation device is positioned between the pressure multiplier and the fluid port. The respirator of claim 1, comprising a central processing unit for packaging raw data collected by at least one of the sensor, the measuring device and the power generating device. The respirator of claim 1 includes a motion sensor. The respirator of claim 1, including means for allowing fluid to leave the respirator during exhalation Exhalation windows and a fluid flow limiter for at least selectively partially closing the expiration windows to set a positive end-expiratory pressure (PEEP) for the living patient. An apparatus suitable for use with a ventilator, comprising: a venturi including: a throat; a venturi nozzle; and a venturi opening in the venturi nozzle through which a pressure-controlled fluid passes Outward flow, wherein the venturi opening leads to the throat, and wherein the venturi opening and the throat are substantially longitudinally aligned; a surrounding fluid aperture fluid with the venturi nozzle and a surrounding fluid communicating; a fluid port; a pressure multiplier in fluid communication with the fluid port; and a valve capable of causing the flow of pressure-controlled fluid to entrain the surrounding fluid to an initial flow position within the throat moving along an axis of movement relative to the venturi opening in the venturi nozzle between stopping the flow of the pressure-controlled fluid entraining the surrounding fluid to a stop-flow position in the throat; wherein the pressure The multiplier is configured such that fluid forced into the fluid port actuates the valve along the axis of movement relative to the venturi nozzle to close the venturi nozzle; wherein the pressure multiplier is configured such that fluid from the fluid port The withdrawn fluid actuates the valve along the axis of movement relative to the venturi nozzle; wherein the axis of movement of the valve is substantially longitudinally aligned with a longitudinal direction of the throat; and wherein the pressure multiplier is positioned therein between the nozzle and the fluid port; and including at least one of a sensor, a measurement device, and a power generation device positioned between at least one of: the venturi nozzle and the surrounding fluid aperture; and the pressure multiplier and the fluid port; and Wherein at least one of the sensor, measuring device and power generation device includes at least one of the following: a pressure sensor, an oxygen sensor, a carbon dioxide sensor, a temperature sensor, a humidity sensor, a pressure sensor Electrical sensors, piezoelectric generators, spirometry measuring devices, pitot measuring probes and spirometry generators. The apparatus of claim 7, wherein at least one of the sensor, the measuring device and the power generating device is positioned between the venturi nozzle and the surrounding air void, and the sensor, measuring device and power generating device At least one of them is positioned between the pressure multiplier and the fluid port. Such as the device of claim 7, wherein in order to collect differential data, at least one of the sensor, the measuring device and the generating device is positioned between the venturi nozzle and the surrounding air void, and a sensor of the same type At least one of a sensor, a measuring device and a power generating device is positioned between the pressure multiplier and the fluid port. The apparatus of claim 7, comprising a central processing unit for encapsulating raw data collected by at least one of the sensor, the measuring device and the power generating device. The device of claim 7 includes a motion sensor. The apparatus of claim 7, comprising at least one fluid gate for allowing fluid to exit the apparatus when fluid is forced into the fluid port and a fluid flow restrictor for at least selectively partially closing the at least one fluid gate. The apparatus of claim 7, wherein the pressure multiplier is configured such that the fluid forced into the fluid port actuates the valve to the stop-flow position along the axis of movement relative to the venturi nozzle; and wherein the The pressure multiplier is configured such that the fluid withdrawn from the fluid port actuates the valve to the start flow position along the axis of movement relative to the venturi nozzle. The apparatus of claim 7, wherein the pressure multiplier is configured such that the fluid forced into the fluid port actuates the valve to the start flow position along the axis of movement relative to the venturi nozzle; and wherein the The pressure multiplier is configured such that withdrawal of fluid from the fluid port actuates the valve to the stop-flow position along the axis of movement relative to the venturi nozzle. The apparatus of claim 7, further comprising a pressure regulator for regulating the flow of the pressure controlled fluid, the pressure regulator comprising: a housing formed to contain an inner bore therein; a piston , which is movably disposed in the inner hole, wherein the piston includes an annular lip adjacent a first end thereof; a spring, which is disposed in the inner hole and includes a first end and a second end; an adjustment cap movably disposed in the inner hole, wherein the adjustment cap is formed to cover Containing a plurality of keyways formed therein; wherein: the first end of the spring is in physical contact with the annular lip; and the second end of the spring is in physical contact with the adjusting cap, wherein: rotates in a first direction The adjusting cap causes the adjusting cap to compress the spring; rotating the adjusting cap in a second and opposite direction causes the adjusting cap to decompress the spring; rotating the adjusting cap in the first direction increases the output pressure of the pressure regulator; Rotating the adjustment cap in the second direction reduces the output pressure of the pressure regulator; the inner hole is defined by a cylindrical wall; the cylindrical wall is formed to include a first thread therein; the adjustment cap is Formed to include a second thread formed on a periphery thereof; and the second thread is configured to engage the first thread. The apparatus of claim 7, wherein the pressure multiplier includes a diaphragm. The apparatus of claim 7, wherein the valve includes a rod having a tapered end, wherein the tapered end enters the venturi opening in the venturi nozzle in the stop position to substantially close the venturi tube opening. The apparatus of claim 7, further comprising at least one filter detachably connected to the surrounding fluid pores. The device of claim 7, wherein the pressure controlled fluid is a liquid. A method of collecting data from a patient using a device suitable for a respirator, the method comprising: providing a pressure-controlled oxygen source; providing a device suitable for a respirator, the device including: a venturi, including a throat; a venturi nozzle; a venturi opening in the venturi nozzle through which pressure-controlled oxygen flows outward, wherein the venturi opening leads to the throat, and wherein the venturi The opening and the throat are substantially longitudinally aligned; a surrounding fluid aperture in fluid communication with the venturi nozzle and surrounding air; a fluid port; and a pressure multiplier in fluid communication with the fluid port, wherein the pressure is multiplied the pressure multiplier includes at least one flange opening defined therethrough; the pressure multiplier includes at least one cover movable between an open position and a closed position relative to the at least one flange opening; and a valve movable Before causing the flow of pressure-controlled oxygen to entrain the ambient air to a start flow position within the throat and stopping the flow of pressure-controlled oxygen to entrain the ambient air to a stop flow position within the throat move along an axis of movement relative to the venturi opening in the venturi nozzle; bring the fluid port into fluid communication with an airway of the patient; and cause the at least one airway in response to the patient exhaling through the fluid port. the cover moves to the closed position relative to the at least one flange opening, and actuating the valve along the axis of movement relative to the venturi nozzle to close the venturi nozzle; and causing movement of the at least one cover relative to the at least one flange opening in response to the patient inhaling through the fluid port to the open position, and actuating the valve along the axis of movement relative to the venturi nozzle; and wherein the axis of movement of the valve is substantially longitudinally aligned with the longitudinal direction of the throat; and includes a sensor , at least one of a measuring device and a power generating device positioned between at least one of: the venturi nozzle and the surrounding air void; and the pressure multiplier and the fluid port; and wherein the sensor . At least one of the measuring device and the power generating device includes at least one of the following: a pressure sensor, an oxygen sensor, a carbon dioxide sensor, a temperature sensor, a humidity sensor, a piezoelectric sensor, A piezoelectric generator, a spirometer measuring device, a pitot measuring probe and a spirometer generator; and using at least one of the sensor, measuring device and power generating device to collect raw data; using a central processing unit unit to encapsulate the collected raw data; use a wired or wireless communication link to transmit the encapsulated raw data to a receiving device; receive the encapsulated data on the receiving device; unpack the collected Original data; quantified and unsealed original data; formatted and quantified data; Analyze the formatted data; distribute the analyzed data; and use an application to display the analyzed data. The method of claim 20, including the step of coupling the central processing unit to the respirator. The method of claim 20, wherein using the wireless communication link includes using at least one wireless protocol selected from Bluetooth, Wi-Fi, and Thread. The method of claim 20, wherein using the wired communication link includes using at least one of a USB, serial, single wire, and parallel. The method of claim 20, including using a smart device to display the analyzed data. The method of claim 24, wherein the smart device includes at least one of a mobile communication device, a tablet computer, a patient interface display, a laptop computer and a desktop computer.