TWI728978B - 在無表面活性劑系統中含有固體脂質顆粒的分散體和使用其的化妝品組合物 - Google Patents

在無表面活性劑系統中含有固體脂質顆粒的分散體和使用其的化妝品組合物 Download PDF

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Publication number: TWI728978B
Authority: TW; Taiwan
Prior art keywords: solid lipid; wax; dispersion; inequality; lipid particles
Prior art date: 2015-06-30

Application number

TW105117834A

Other languages

English (en)

Chinese (zh)

Other versions

TW201702315A (zh

Inventor

崔守廷

金度勳

朴勝寒

朴城逸

蔡秉根

Original Assignee

南韓商愛茉莉太平洋股份有限公司

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-06-30

Filing date

2016-06-06

Publication date

2021-06-01

2016-06-06 Application filed by 南韓商愛茉莉太平洋股份有限公司 filed Critical 南韓商愛茉莉太平洋股份有限公司

2017-01-16 Publication of TW201702315A publication Critical patent/TW201702315A/zh

2021-06-01 Application granted granted Critical

2021-06-01 Publication of TWI728978B publication Critical patent/TWI728978B/zh

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150000002632 lipids Chemical class 0.000 title claims abstract description 80
239000002245 particle Substances 0.000 title claims abstract description 58
239000007787 solid Substances 0.000 title claims abstract description 58
239000006185 dispersion Substances 0.000 title claims abstract description 57
239000000203 mixture Substances 0.000 title claims abstract description 46
239000002537 cosmetic Substances 0.000 title claims abstract description 22
239000001993 wax Substances 0.000 claims description 41
239000003921 oil Substances 0.000 claims description 33
235000019198 oils Nutrition 0.000 claims description 33
-1 hydroxyethyl Ester Chemical class 0.000 claims description 21
238000002844 melting Methods 0.000 claims description 21
230000008018 melting Effects 0.000 claims description 21
239000013078 crystal Substances 0.000 claims description 17
238000001953 recrystallisation Methods 0.000 claims description 17
238000001816 cooling Methods 0.000 claims description 9
239000002562 thickening agent Substances 0.000 claims description 9
238000010438 heat treatment Methods 0.000 claims description 7
229920002845 Poly(methacrylic acid) Polymers 0.000 claims description 6
235000015112 vegetable and seed oil Nutrition 0.000 claims description 6
239000004215 Carbon black (E152) Substances 0.000 claims description 5
239000004698 Polyethylene Substances 0.000 claims description 5
239000008346 aqueous phase Substances 0.000 claims description 5
125000004432 carbon atom Chemical group C* 0.000 claims description 5
229920001577 copolymer Polymers 0.000 claims description 5
235000014113 dietary fatty acids Nutrition 0.000 claims description 5
239000000194 fatty acid Substances 0.000 claims description 5
229930195729 fatty acid Natural products 0.000 claims description 5
229930195733 hydrocarbon Natural products 0.000 claims description 5
150000002430 hydrocarbons Chemical class 0.000 claims description 5
229920000573 polyethylene Polymers 0.000 claims description 5
150000004665 fatty acids Chemical class 0.000 claims description 4
239000012184 mineral wax Substances 0.000 claims description 4
229920002401 polyacrylamide Polymers 0.000 claims description 4
239000008158 vegetable oil Substances 0.000 claims description 4
239000012178 vegetable wax Substances 0.000 claims description 4
229920002125 Sokalan® Polymers 0.000 claims description 3
239000012164 animal wax Substances 0.000 claims description 3
239000010696 ester oil Substances 0.000 claims description 3
239000004584 polyacrylic acid Substances 0.000 claims description 3
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KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 2
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239000002202 Polyethylene glycol Substances 0.000 claims description 2
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UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 2
239000000230 xanthan gum Substances 0.000 claims description 2
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FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 claims 1
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GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 4
PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 4
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DSEKYWAQQVUQTP-XEWMWGOFSA-N (2r,4r,4as,6as,6as,6br,8ar,12ar,14as,14bs)-2-hydroxy-4,4a,6a,6b,8a,11,11,14a-octamethyl-2,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-tetradecahydro-1h-picen-3-one Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3C[C@@H](O)C(=O)[C@@H]1C DSEKYWAQQVUQTP-XEWMWGOFSA-N 0.000 description 2
CZVOIAOPRGNENY-UHFFFAOYSA-N 2-butyloctyl 2-hydroxybenzoate Chemical compound CCCCCCC(CCCC)COC(=O)C1=CC=CC=C1O CZVOIAOPRGNENY-UHFFFAOYSA-N 0.000 description 2
BGRXBNZMPMGLQI-UHFFFAOYSA-N 2-octyldodecyl tetradecanoate Chemical compound CCCCCCCCCCCCCC(=O)OCC(CCCCCCCC)CCCCCCCCCC BGRXBNZMPMGLQI-UHFFFAOYSA-N 0.000 description 2
HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 2
XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 2
206010016322 Feeling abnormal Diseases 0.000 description 2
RGMZNZABJYWAEC-UHFFFAOYSA-N Methyltris(trimethylsiloxy)silane Chemical compound C[Si](C)(C)O[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C RGMZNZABJYWAEC-UHFFFAOYSA-N 0.000 description 2
240000007594 Oryza sativa Species 0.000 description 2
235000007164 Oryza sativa Nutrition 0.000 description 2
241001135917 Vitellaria paradoxa Species 0.000 description 2
235000018936 Vitellaria paradoxa Nutrition 0.000 description 2
RDVFKSXIXOQIDZ-UHFFFAOYSA-N [3-hydroxy-2,2-bis(hydroxymethyl)propyl] 2,2,3,3-tetraethylhexanoate Chemical compound CCCC(CC)(CC)C(CC)(CC)C(=O)OCC(CO)(CO)CO RDVFKSXIXOQIDZ-UHFFFAOYSA-N 0.000 description 2
239000008163 avocado oil Substances 0.000 description 2
235000021302 avocado oil Nutrition 0.000 description 2
235000021028 berry Nutrition 0.000 description 2
230000015572 biosynthetic process Effects 0.000 description 2
238000007707 calorimetry Methods 0.000 description 2
239000004204 candelilla wax Substances 0.000 description 2
235000013868 candelilla wax Nutrition 0.000 description 2
229940073532 candelilla wax Drugs 0.000 description 2
239000004203 carnauba wax Substances 0.000 description 2
235000013869 carnauba wax Nutrition 0.000 description 2
239000000969 carrier Substances 0.000 description 2
229960000541 cetyl alcohol Drugs 0.000 description 2
230000007423 decrease Effects 0.000 description 2
230000003247 decreasing effect Effects 0.000 description 2
239000004205 dimethyl polysiloxane Substances 0.000 description 2
235000013870 dimethyl polysiloxane Nutrition 0.000 description 2
PKPOVTYZGGYDIJ-UHFFFAOYSA-N dioctyl carbonate Chemical compound CCCCCCCCOC(=O)OCCCCCCCC PKPOVTYZGGYDIJ-UHFFFAOYSA-N 0.000 description 2
NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 description 2
229940079593 drug Drugs 0.000 description 2
239000003814 drug Substances 0.000 description 2
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IUJAMGNYPWYUPM-UHFFFAOYSA-N hentriacontane Chemical compound CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC IUJAMGNYPWYUPM-UHFFFAOYSA-N 0.000 description 2
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125000001165 hydrophobic group Chemical group 0.000 description 2
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230000005923 long-lasting effect Effects 0.000 description 2
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239000004200 microcrystalline wax Substances 0.000 description 2
235000019808 microcrystalline wax Nutrition 0.000 description 2
JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 2
GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 2
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230000002829 reductive effect Effects 0.000 description 2
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238000000926 separation method Methods 0.000 description 2
230000005808 skin problem Effects 0.000 description 2
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239000000126 substance Substances 0.000 description 2
238000002076 thermal analysis method Methods 0.000 description 2
RUHCWQAFCGVQJX-RVWHZBQESA-N (3s,8s,9s,10r,13r,14s,17r)-3-hydroxy-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-1-one Chemical compound C1C=C2C[C@H](O)CC(=O)[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 RUHCWQAFCGVQJX-RVWHZBQESA-N 0.000 description 1
ABEXEQSGABRUHS-UHFFFAOYSA-N 16-methylheptadecyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCCCCCC(C)C ABEXEQSGABRUHS-UHFFFAOYSA-N 0.000 description 1
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229920000742 Cotton Polymers 0.000 description 1
244000020551 Helianthus annuus Species 0.000 description 1
235000003222 Helianthus annuus Nutrition 0.000 description 1
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230000002776 aggregation Effects 0.000 description 1
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150000001298 alcohols Chemical class 0.000 description 1
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235000013871 bee wax Nutrition 0.000 description 1
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238000006731 degradation reaction Methods 0.000 description 1
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239000000645 desinfectant Substances 0.000 description 1
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XJFGDLJQUJQUEI-UHFFFAOYSA-N dodecyl decanoate dodecyl octanoate Chemical compound CCCCCCCCCCCCOC(=O)CCCCCCC.CCCCCCCCCCCCOC(=O)CCCCCCCCC XJFGDLJQUJQUEI-UHFFFAOYSA-N 0.000 description 1
230000001804 emulsifying effect Effects 0.000 description 1
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150000002148 esters Chemical class 0.000 description 1
150000002170 ethers Chemical class 0.000 description 1
235000019197 fats Nutrition 0.000 description 1
239000000835 fiber Substances 0.000 description 1
239000003205 fragrance Substances 0.000 description 1
ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
LNEPOXFFQSENCJ-UHFFFAOYSA-N haloperidol Chemical compound C1CC(O)(C=2C=CC(Cl)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 LNEPOXFFQSENCJ-UHFFFAOYSA-N 0.000 description 1
DWMMZQMXUWUJME-UHFFFAOYSA-N hexadecyl octanoate Chemical compound CCCCCCCCCCCCCCCCOC(=O)CCCCCCC DWMMZQMXUWUJME-UHFFFAOYSA-N 0.000 description 1
239000000017 hydrogel Substances 0.000 description 1
239000008172 hydrogenated vegetable oil Substances 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
XUGNVMKQXJXZCD-UHFFFAOYSA-N isopropyl palmitate Chemical class CCCCCCCCCCCCCCCC(=O)OC(C)C XUGNVMKQXJXZCD-UHFFFAOYSA-N 0.000 description 1
229940060384 isostearyl isostearate Drugs 0.000 description 1
239000002502 liposome Substances 0.000 description 1
239000002932 luster Substances 0.000 description 1
238000005259 measurement Methods 0.000 description 1
239000000155 melt Substances 0.000 description 1
238000000034 method Methods 0.000 description 1
239000002480 mineral oil Substances 0.000 description 1
235000010446 mineral oil Nutrition 0.000 description 1
CMNMHJVRZHGAAK-UHFFFAOYSA-N n-caproic acid n-octyl ester Natural products CCCCCCCCOC(=O)CCCCC CMNMHJVRZHGAAK-UHFFFAOYSA-N 0.000 description 1
239000002086 nanomaterial Substances 0.000 description 1
239000002105 nanoparticle Substances 0.000 description 1
239000010466 nut oil Substances 0.000 description 1
230000003647 oxidation Effects 0.000 description 1
238000007254 oxidation reaction Methods 0.000 description 1
229940057874 phenyl trimethicone Drugs 0.000 description 1
239000000049 pigment Substances 0.000 description 1
229920002338 polyhydroxyethylmethacrylate Polymers 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
229920001296 polysiloxane Polymers 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
238000000197 pyrolysis Methods 0.000 description 1
239000011347 resin Substances 0.000 description 1
229920005989 resin Polymers 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
150000004671 saturated fatty acids Chemical class 0.000 description 1
235000003441 saturated fatty acids Nutrition 0.000 description 1
230000037307 sensitive skin Effects 0.000 description 1
229940057910 shea butter Drugs 0.000 description 1
230000036556 skin irritation Effects 0.000 description 1
231100000475 skin irritation Toxicity 0.000 description 1
230000036548 skin texture Effects 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
235000020238 sunflower seed Nutrition 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
238000010257 thawing Methods 0.000 description 1
125000003944 tolyl group Chemical group 0.000 description 1
239000003860 topical agent Substances 0.000 description 1
LINXHFKHZLOLEI-UHFFFAOYSA-N trimethyl-[phenyl-bis(trimethylsilyloxy)silyl]oxysilane Chemical compound C[Si](C)(C)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)C1=CC=CC=C1 LINXHFKHZLOLEI-UHFFFAOYSA-N 0.000 description 1

Images

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Birds (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Emergency Medicine (AREA)
Cosmetics (AREA)
Zoology (AREA)

TW105117834A 2015-06-30 2016-06-06 在無表面活性劑系統中含有固體脂質顆粒的分散體和使用其的化妝品組合物 TWI728978B (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR1020150093463A KR102406641B1 (ko)	2015-06-30	2015-06-30	무계면활성제 시스템의 고형 지질 미립자를 포함하는 분산액 및 이를 이용한 화장료 조성물
KR10-2015-0093463		2015-06-30

Publications (2)

Publication Number	Publication Date
TW201702315A TW201702315A (zh)	2017-01-16
TWI728978B true TWI728978B (zh)	2021-06-01

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TW105117834A TWI728978B (zh)	2015-06-30	2016-06-06	在無表面活性劑系統中含有固體脂質顆粒的分散體和使用其的化妝品組合物

Country Status (4)

Country	Link
KR (1)	KR102406641B1 (ko)
CN (1)	CN107735074B (ko)
TW (1)	TWI728978B (ko)
WO (1)	WO2017003080A1 (ko)

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Publication number	Priority date	Publication date	Assignee	Title
EP3655108A4 (en) *	2017-07-19	2021-01-27	Henkel AG & Co. KGaA	CONDITIONING COMPOSITION FOR HAIR HAVING A SNOWMELTING EFFECT
KR102224314B1 (ko)	2017-07-31	2021-03-09	(주)아모레퍼시픽	구형 입자를 포함하는 분산 제형 화장료 조성물
CN110585070A (zh) *	2019-09-12	2019-12-20	北京植物医生生物科技有限公司	含有悬浮粒子的化妆品及其制备方法
KR102462350B1 (ko) *	2020-07-13	2022-11-03	주식회사 알엠사이언스	이데베논 또는 이의 약학적으로 허용가능한 염을 함유하는 지질 비드 및 이의 제조방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200900087A (en) *	2007-04-17	2009-01-01	Kao Corp	Hair cosmetic composition
WO2014079734A1 (de) *	2012-11-20	2014-05-30	Beiersdorf Ag	Sensorisch attraktive hydrodispersion mit wachsen
TW201505661A (zh) *	2013-06-07	2015-02-16	Kao Corp	水中油型乳化皮膚化妝料

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CN107735074B (zh)	2021-07-20
TW201702315A (zh)	2017-01-16
KR20170003163A (ko)	2017-01-09
WO2017003080A1 (ko)	2017-01-05
CN107735074A (zh)	2018-02-23
KR102406641B1 (ko)	2022-06-08
HK1243920A1 (zh)	2018-07-27

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