TWI712425B - Skin physiotherapy formula of deep sea water concentrate for mature skin appearance improvement and the use thereof - Google Patents

Abstract

The present invention provides a skin physiotherapy formula of deep sea water concentrate mature skin appearance improvement and the use thereof; wherein the method including provide a first agent, a second agent and a fiber membrane, and applying on a subject with an importer; the electric current of the applying is 0.1~0.8mA/cm².

Description

Application and method of deep ocean concentrate skin physiotherapy formula for improving the aging appearance of human body

The present invention is an application and method of a skin physiotherapy formula of deep sea concentrate for improving skin appearance; the steps include providing a deep sea concentrate, a skin physiotherapy formula and a fiber membrane, and applying them to the surface of an affected area, and It is especially related to the use of a lead-in instrument for application.

Deep-sea water (DSW) is taken from low-temperature, clean and pollution-free sea water below sea level 200 meters. Its characteristics include: (1) Cleanliness: deep sea water is different from surface sea water, deep sea water Unaffected by man-made pollution, in the precipitation process of surface seawater, bacteria will decompose due to chemical acidification, precipitation, migration and diffusion, and will gradually decrease with depth. Because there are no organic substances required by the remaining bacteria in the deep sea and no nitrate nitrogen supply, bacteria are difficult to multiply. Therefore, the content of various harmful bacteria or germs that cause disease is extremely scarce in deep seawater, which is only one thousandth to one ten thousandth of that of surface water. In addition, the organic matter remaining in the deep seawater is quite stable against the action of microorganisms to decompose the residual organic matter. This is why the deep seawater quality is relatively stable, inorganic and clean in terms of microbiology or physical chemistry. (2) Low temperature: Since the sun's rays cannot reach the deep seawater, the water temperature is lower than that of the surface seawater, and the temperature is relatively unchanged, and the low temperature is stable throughout the year. (3) Rich Inorganic Nutrients: Due to the lack of light in the deep seawater, organisms cannot perform photosynthesis, so the necessary nutrients required by plant plankton—nitrogen, phosphorus, silicon, nitric acid, etc., cannot be consumed, and a large amount of them accumulate in the deep seawater . (4) Stability of maturation: Under the influence of high pressure and isolation from the atmosphere, the composition of deep seawater is stable for many years. (5) Rich in minerals: The minerals in the ocean mainly come from the rock formations and are washed to the ocean by rainwater to form water-soluble minerals, which are evenly distributed in the sea. .

In recent years, deep ocean water has been widely used in food processing industry, agriculture, and medicine. Some research literature points out that deep ocean water can reduce blood fat, lipid oxidation, vascular sclerosis and hypertension, as well as vascular wall hyperplasia; although in the research of atopic dermatitis, it is also found that patients are drinking or soaking deep Sea water can improve skin inflammation and allergies, but it has not been widely used in the cosmetics industry. In addition, drinking deep ocean water has also been found to be used to improve cataracts. It has also been pointed out in the literature that it has been found in cell experiments that deep ocean water can stimulate the regeneration of collagen, whiten the skin, and inhibit or treat inflammation.

Various types of cosmetics or skin care products on the market are not easily absorbed by the skin because they are macromolecules and deep-sea concentrates have high surface tension. Furthermore, skin care products and cosmetics mixed with deep-sea concentrate or deep-sea water will deteriorate after a period of time. Therefore, skin care products and cosmetics should not be left for too long after being mixed with deep ocean concentrate or deep ocean water. The present invention provides a method for applying deep ocean concentrate skin physiotherapy formula to the affected area, which can solve the above problems and make the skin care products compatible with the ocean. The deep concentrate quickly penetrates the sebum membrane and reaches the dermis, improving the patient's appearance and appearance.

In view of this, the present invention provides an application and method of deep-sea concentrate skin physiotherapy formula for improving aging appearance. Moreover, the skin physiotherapy formula of deep sea concentrate of the present invention is characterized in that it has a physiotherapy formula for immediate micronization of the skin, immediately reduces the high surface tension of the deep sea concentrate, solves the problem of difficult skin absorption and the material characteristics of the deep sea concentrate, It becomes the driving force for the penetration of the micronized skin with the physiotherapy formula, and when used with the introduction device, the skin physiotherapy formula can quickly penetrate the sebum membrane, reach the dermis, and slow down the loss of collagen. Anti-aging effect.

The present invention provides a method for using a deep-sea concentrate skin physiotherapy formula, the steps of which include: (a) providing a first agent, wherein the first agent is a deep ocean concentrate; (b) providing a second agent, wherein The second agent is a physiotherapy formula for skin; (c) a fiber membrane is provided, and the fiber membrane is first infiltrated in the second agent and then in the first agent to form an infiltrating fiber membrane; (d) the infiltration The fiber membrane is immediately applied to the surface of an affected area; (e) an introducer is applied to the infiltrated fiber membrane, the current applied by the introducer is 0.1mA~0.8mA per square centimeter, and the application time per square centimeter is 15-30 Seconds; wherein, through the step (e), the first agent and the second agent can quickly penetrate the sebum membrane to reach the dermis, and stimulate collagen proliferation.

Preferably, the effective concentration of the first agent in the infiltrated fiber membrane is at least greater than or equal to 1.25 (v/v)%.

Preferably, in step d), the infiltrated fiber membrane is applied to the affected part within 10 minutes.

Preferably, in step e), the introduction instrument is applied to the infiltrated fiber membrane within 10 minutes.

Preferably, the affected part is the face, arm, abdomen or leg.

Preferably, the current applied by the introduction device is 0.1mA~0.8mA/cm ² due to the size and position of the fiber membrane used in the affected area, and the application time is 15-30 seconds/cm ² of the affected area.

Preferably, the magnesium concentration of the first dose is 6,500-110,000 mg/l, the sodium concentration is 3,800-30,000 mg/l, the potassium concentration is 400-18,000 mg/l, and the calcium concentration is 100-500 mg/l. The hardness is 80,000~420,000mg/l, and the salinity is 380~430‰. The first dose contains 1000~1500mg calcium, 1400~2100mg magnesium, 2000~4000mg sodium, 1400~2100mg potassium, sulfate <6.5wt% per 100g, and the specific gravity is 1.17~1.32g/cm ³ ocean Mineral solution. Preferably, the first agent is taken from a water source below 200 m in the ocean; preferably, the first agent is taken from a water source below 500 m in the ocean. Preferably, the first agent is liquid or powder.

Preferably, the second agent is an anti-aging, lifting, firming, whitening, moisturizing, medical or cosmetic introduction product, and a product for promoting collagen proliferation. Preferably, the second agent is gel-like. .

Preferably, the induction device includes a power feeding device and a sensor. The power feeding device includes an outer surface and an interior; wherein, the outer surface of the power feeding device includes: an operation panel disposed on one of the aforementioned physical therapy devices On the side, a control command is provided to regulate a direct current output from the aforementioned power supply device. The aforementioned direct current is a combination of positive and negative electricity of different strengths and different time ratios; a sensor connection hole for connecting the aforementioned sensor, the aforementioned sensor connection hole further has A stable current detection circuit is electrically connected to a control circuit and the aforementioned sensor connection hole for amplifying the voltage of a stimulating current; and a power input terminal is arranged on the other side of the aforementioned physical therapy device to provide a power source for the aforementioned electrical device The aforementioned power input terminal further has a plurality of safety circuits, which are electrically connected to the aforementioned control circuit and the aforementioned power input terminal to control the different voltages of the aforementioned power source; wherein, the aforementioned power supply device is equipped with the aforementioned control circuit, which is electrically connected to the aforementioned operation The panel obtains the aforementioned control commands and the aforementioned power input terminal obtains the aforementioned power supply, and outputs the aforementioned direct current through the sensor connection hole, including: a fixed actual body circuit for controlling the different intensities of the aforementioned direct current; and an on-off valve circuit through The aforementioned control command selects to control the positive and negative electricity of the aforementioned direct current; wherein, the aforementioned sensor refers to the aforementioned sensor connection hole of the aforementioned power supply device with a wire connected to it, which has a discharge terminal with a specific area interface, so that the aforementioned direct current outputs the aforementioned stimulus through the aforementioned sensor Current.

Preferably, the current is introduced into the apparatus administered 2mA ~ 25mA, preferably, fiber membrane according to the magnitude of the current change, a current per square centimeter administered 0.1 ~ 0.8mA, applied to the affected area as time fiber membrane 15 to 30 seconds / c ^m2 .

Preferably, according to the size of the fiber membrane, the usage amount of the second agent is 0.4 grams per square centimeter.

To achieve the foregoing and other objectives, one or more specific embodiments of the present invention will be described below. Other features or advantages of the present invention are described in detail with embodiments and claims.

125‧‧‧Safety circuit

126‧‧‧Fixed measured human body circuit

127‧‧‧Stable current detection circuit

Figure 1 is a schematic diagram of changes in the aging appearance of the human face.

Figures 2A-2C show the comparison of the use method of the present invention before and after the use of the eyes, and the changes in the eyes. Picture 2A is before use, picture 2B is after use, and picture 2C is one day after use. Dark circles and crow's feet after use

Figures 2D-2F show the comparison of the use method of the present invention before and after the use of the eyes, and the changes in the eyes. Picture 2D is before use, Picture 2E is after use, Picture 2F is one day after use.

Figures 3A-3C show the comparison of the use method of the present invention before and after the use of the face, the changes in the law pattern and the marionette pattern. Picture 3A is before use, picture 3B is the fourth day after use, and picture 3C is the fifth day after use.

Figures 3D and 3E show the comparison of the use method of the present invention before and after the use of the face, and the changes of the law pattern and the puppet pattern. Picture 3D is before use, Picture 3E is after use.

Figures 4A-4B show the comparison of the application method of the present invention on the face before and after use, and the changes in the looseness of the neck (ie double chin). Picture 4A is before use, Picture 4B is after use.

Figure 5 is a schematic diagram of the control circuit of the importer

Figures 6A and 6B show the effect of deep ocean concentrate on inhibiting the enzyme activity of matrix metalloproteinase-1 and matrix metalloproteinase-3.

Figure 7 shows the effect of deep ocean concentrate on increasing the secretion of collagen.

The present invention provides an application and method for improving the appearance and appearance of a skin physiotherapy formula of deep ocean concentrate.

The "deep ocean water" in the present invention refers to seawater taken from 200 to 1500 meters below sea level, preferably 500 to 700 meters below sea level, and each 100g of dissolved (liquid/powder) contains 1000~ 1500mg calcium, 1400-2100mg magnesium, 2000-4000mg sodium, 1400-2100mg potassium, sulfate <6.5wt%, and a specific gravity of 1.17-1.32g/cm ³ marine mineral solution.

The "deep ocean concentrate" mentioned in the present invention refers to the liquid or powder produced after the deep ocean water is concentrated. This deep ocean concentration (liquid/powder) concentration process uses fiber filtration systems, ultrafiltration systems, seawater reverse osmosis systems, low-temperature vacuum evaporation concentration systems and/or centrifugation.

The deep ocean concentrate has a hardness of 80,000~420,000mg/l, a salinity of 380~430‰, a magnesium concentration of 6,500~110,000mg/l and a sodium concentration of 3,800~30,000mg/l. The deep ocean concentrate of the present invention is rich in a variety of minerals, including, but not limited to, calcium (Ca), potassium (K), iron (Fe), zinc (Zn), molybdenum (Mo), manganese (Mn), lithium (Li), Strontium (Sr), Copper (Cu), Silicon (Si) and other trace elements. In one embodiment, the composition of the deep-sea concentrate is shown in Table 1, but since the testing unit has not completed the complete element detection, the deep-sea concentrate of the present invention is not limited to this.

Table 1. Composition of deep ocean concentrate

The "fibrous membrane" in the present invention refers to an ultra-fine long-fibre facial mask.

The "infiltrated fiber membrane" in the present invention refers to the fiber membrane after being soaked in the skin physiotherapy formula and the deep ocean concentrate, which contains a mixture of the deep ocean concentrate and the skin physiotherapy formula.

The "skin physiotherapy formula" mentioned in the present invention refers to general gel formula products and formulas used in treatment courses in beauty-related institutions. For example, whitening products, moisturizing products, wrinkle removal products, wound healing products, quick-healing treatments and other products that improve the appearance of the skin.

The "mixture of deep ocean concentrate and skin physiotherapy formula" or "mixture of first agent and second agent" in the present invention refers to the deep ocean concentrate after the fibrous membrane is soaked in the skin physiotherapy formula and the deep ocean concentrate It will be mixed in the skin physiotherapy formula, that is, the fiber membrane will contain a mixture of deep ocean concentrate and skin physiotherapy formula.

However, after the deep-sea concentrate is mixed into the skin treatment formula for a period of time, the deep-sea concentrate will cause the skin treatment formula to deteriorate, become unstable and disintegrate. Therefore, after the fiber membrane of the present invention is soaked in the second agent and then in the first agent, it is applied to the surface of the affected area within 10 days after the infiltration is completed, preferably 9 days, 8 days, 7 days, and 6 days , 5 days, 4 days, 3 days, 2 days, 1 day after use, the best is within 12 hours, 6 hours, 3 hours, 2 hours, 1 hour.

After mixing the deep ocean concentrate into the skin treatment formula, the skin treatment formula will deteriorate significantly after only 10 days. In addition, the deep-sea concentrate will produce unidentified sediments and floats in the skin treatment formula, which shows that if the deep-sea concentrate is mixed into the skin treatment formula for a period of time, its ions and ingredients will undergo chemical changes, reducing the original skin The effect of physiotherapy formula on the skin may even produce derivatives that may be harmful to the skin.

There are no special restrictions on the way of fiber membrane infiltration, and general methods can be used. For example, the fiber membrane is soaked in a plastic wrap bag containing skin physiotherapy formula, and then the deep ocean concentrate is added to the plastic wrap bag to make the fiber The membrane is immersed in the deep ocean concentrate. There is no special restriction on the time the fiber membrane is soaked in the skin physiotherapy formula, but because it must be used as soon as possible after the fiber membrane is immersed in the deep ocean concentrate to avoid deterioration of the quality of the skin physiotherapy formula, the time for the fiber membrane to soak into the deep ocean concentrate It should not be too long, usually within 15 minutes, preferably within 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, 4, 3 minutes, and most preferably within 10 minutes. The infiltration fiber membrane should not be placed for too long. It is usually applied to the surface of the affected area within 15 minutes, preferably within 14, 13, 12, 11, 10, 9, 8, 7, 6, 5, 4, and 3 minutes. , The best is within 10 minutes. After the infiltrated fiber membrane is applied to the surface of the affected area, it is also necessary to apply the introducer to the infiltrated fiber membrane as soon as possible, usually within 15 minutes, apply the introducer to the infiltrated fiber membrane, preferably 14, 13, 12, 11, 10 , 9, 8, 7, 6, 5, 4, 3 minutes, preferably within 10 minutes.

As mentioned above, the infiltrating fiber membrane must be applied to the affected area as soon as possible, and introduced as soon as possible with the introduction device to avoid changes in the quality of the skin physiotherapy formula.

After the fiber membrane is infiltrated in the skin physiotherapy formula and the deep ocean concentrate, the deep ocean concentrate will be mixed with the skin physiotherapy formula, and can immediately produce phase transfer to make the molecules of the skin care products smaller, and use it with the introduction device. The mixture of deep ocean concentrate and skin treatment formula easily penetrates the sebum membrane and reaches the dermis.

[Example]

The method of use in this embodiment is based on the size of the fiber membrane, using 0.4 g per square centimeter of skin physiotherapy formula to infiltrate the fiber membrane, and then use 0.4 g per square centimeter of deep ocean concentrate to infiltrate the fiber membrane. And apply the introduction device on the surface of the infiltrated fiber membrane, the current applied by the introduction device is 0.1mA~0.8mA per square centimeter, and the application time per square centimeter is 15-30 seconds.

Example 4. 56 human face test results

The test subjects are 20-85 years old who want to improve their facial appearance. There are 37 women and 19 men. Please refer to Table 1 for the age of the test subjects.

Implementation mode: Put the fiber membrane into a fresh-keeping bag containing the skin physiotherapy formula, and then pour the deep sea concentrate into the above-mentioned fresh-keeping film, so that the fiber membrane is first soaked in the skin physiotherapy formula and then in the deep sea concentrate , Get an infiltrated fiber membrane. At this time, the infiltrated fiber membrane contains a mixture of deep sea concentrate and skin physiotherapy formula, wherein the effective concentration of the deep sea concentrate is at least greater than or equal to 1.25 (v/v)%. Then take out the infiltrated fiber membrane and apply it on the face immediately, and then use the introducer on the infiltrated fiber membrane. The current applied by the introducer is to change the current according to the size of the fiber membrane, and the current is 0.1~0.8mA per square centimeter , The application time is 15-30 seconds/cm ^{2 of the} fibrous membrane of the affected area.

For the results, please refer to Table 2, Table 3 and Figures 2 to 4. Among them, after implementation, to improve facial fine lines, as well as to improve the "eye bags, drooping eye tails, crow's feet, eyelid drooping, eyebrow lines, nasolabial lines, marionette lines, jaw lines, and double chins" that require invasive treatment to improve. , Neck wrinkles, dark circles, acne scars" and other appearance problems.

Figure 2A is the eye before using the method of the present invention, Figure 2B is the eye change after using the method of the present invention, and Figure 2C is the eye change one day after using the method of the present invention. In Figure 2B, fine lines around the eyes, eye bags, drooping eye tails, crow's feet, drooping eyelids, and brow lines have all been improved. In Figure 2C, fine lines around the eyes, bags under the eyes, drooping eye tails, crow's feet, drooping eyelids, and brow lines are further improved.

Figure 2D is the eye before using the method of the present invention, Figure 2E is the eye change after using the method of the present invention, and Figure 2F is the eye change one day after using the method of the present invention. In Figure 2E, the fine lines around the eyes, eye bags, drooping eye tails, crow's feet, drooping eyelids, and brow lines have all been improved. In Figure 2F, fine lines around the eyes, eye bags, drooping eye tails, crow's feet, drooping eyelids, and eyebrow lines are further improved.

Figures 3A-3C show the comparison of the application method of the present invention before and after the use of the whole face, and the changes of the whole face. Picture 3A is before use, picture 3B is the fourth day after use, and picture 3C is the fifth day after use. Figure 3B Fine lines, eye bags, drooping eye tails, crow's feet, drooping eyelids, eyebrow lines, nasolabial lines, marionette lines, jaw lines, double chin, neck lines, and dark circles have all been improved. In Figure 3C, eye bags, drooping eye tails, chin lines, and double chin have been significantly improved, and both sides of the cheeks have been lifted. .

Figures 3D and 3E show the comparison of the application method of the present invention before and after the use of the face, and the overall changes of the face. Picture 3D is before use, Picture 3E is after use. In Figure 3E, fine lines, eye bags, drooping eye tails, crow's feet, drooping eyelids, eyebrow lines, nasolabial lines, marionette lines, chin lines, double chins, neck lines, and dark circles are the lines of the chin. Obviously lifting effect.

Figures 4A-4B show the comparison of the application method of the present invention on the face before and after use, and the changes in the looseness of the neck (ie double chin). Picture 4A is before use, Picture 4B is after use. In Figure 4B, the neck relaxation has been significantly improved, and there is a significant effect of jaw lifting.

Example 6. Introduction instrument

The method of use of the present invention is used with a lead-in instrument. The lead-in instrument can be a general commercially available lead-in instrument. Preferably, please refer to the schematic diagram of the control circuit of the lead-in instrument in Figure 5. The lead-in instrument includes a power supply device and a sensor. The device includes an outer surface and an interior; wherein, the outer surface of the power feeding device includes: an operation panel, which is arranged on a side of the physical therapy device, so as to provide a control command to regulate a direct current output by the power feeding device, The aforementioned direct current is a combination of positive and negative electricity of different intensities and different time ratios; a sensor connection hole, through which the aforementioned sensor is connected, the aforementioned sensor connection hole has a stable current detection circuit 127, which is electrically connected to a control circuit and the aforementioned sensor A hole for amplifying the voltage of a stimulating current; and a power input terminal arranged on the other side of the physiotherapy device to provide a power supply for the electric device. The power input terminal further has a plurality of safety circuits 125, which are electrically connected to the control The circuit and the aforementioned power input terminal are used to control the different voltages of the aforementioned power source; wherein, the aforementioned power feeding device is equipped with the aforementioned control circuit, which is electrically connected to the operation panel to obtain the aforementioned control command and the aforementioned power input terminal to obtain the aforementioned power supply, and Outputting the aforementioned direct current through the aforementioned sensor connection hole includes: a fixed actual human body circuit 126 for controlling the different intensities of the aforementioned direct current; and a switch valve circuit, selected by the aforementioned control command, to control the positive and negative of the aforementioned direct current; wherein, the aforementioned The sensor refers to the sensor connection hole of the power supply device connected with a wire, which has a discharge terminal with a specific area interface, so that the direct current can output the stimulation current through the sensor.

Example 7. Inhibition of collagen loss

Please refer to Figure 6A, Figure 6B, Table 3 and Table 4, the present invention commissioned the Industrial Technology Research Institute to use in vitro test tube experiments to study the inhibition of matrix metalloproteinase-1 (MMP-1) and matrix by deep ocean concentrates. The potency of metalloproteinase-3 (Matrix Metalloproteinase-3, MMP-3). Matrix metalloproteinase-1 and matrix metalloproteinase-3 are two of the commonly known collagen degrading enzymes. In order to regulate the important factors of photoaging, the exposure of fibroblasts to the ultraviolet rays of the sun will cause a large amount of matrix metalloproteinases to be expressed, and then degrade the extracellular Extracellular matrix (ECM), which means that MMP-1 and MMP-3 are responsible for the degradation and loss of collagen in the dermal tissue. This experiment proves that the deep ocean concentrate has the function of inhibiting the loss of collagen. NNGH (N-Isobutyl-N-(4-methoxyphenylsulfonyl)glycyl hydroxamic acid) is an inactivating drug for matrix metalloproteinase (MMP inactivating drug). According to the experimental data in Figures 6A and 6B, compared with the inhibition rate of NNGH (VS.NNGH), the 0.5% concentration of deep ocean concentrate can relatively inhibit 4.92% of matrix metalloproteinase-1 activity and 2.18% of matrix metal Protease-3 activity. 1% concentration of deep ocean concentrate can inhibit 15.13% of matrix metalloproteinase-1 activity and 8.12% of matrix metalloproteinase-3 activity. A 2% concentration of deep ocean concentrate can inhibit up to 23.93% of matrix metalloproteinase-1 activity and 27.71% of matrix metalloproteinase-3 activity. This experiment shows that the deep ocean concentrate can effectively inhibit the enzyme activity of matrix metalloproteinase-1 and matrix metalloproteinase-3. Compared with the inhibition rate of NNGH, the effect of inhibiting the activity of matrix metalloproteinase-1 and matrix metalloproteinase-3 is as high as 50%. . It means that the deep ocean concentrate has the effect of inhibiting the loss of collagen, promotes skin cells to show better health, and is conducive to the addition of all effective ingredients for skin cells.

Example 8. Increase collagen secretion

Please refer to Figure 7. This experiment uses 0-1% deep ocean concentrate with vitamin C compound to show the amount of collagen secreted by different concentrations of deep ocean concentrate.

Example 9. Electronic state

After the skin care formula is mixed with the deep sea concentrate, the surface electrodes of the microsomes and their charges (not shown) are generated, and the time ratio of the direct current positive current and the negative current application is designed according to the ratio.

All the features disclosed in the invention can be realized in any combination. Each feature disclosed in the present invention should be replaced by substitutes with the same, equal or similar purpose. Therefore, unless explicitly specified, each feature disclosed is merely an example of a category of equivalents or similar features.

Claims (8)

A beautification method of a deep-sea concentrate skin conditioning formula, which steps include: (a) providing a first agent, wherein the first agent is a deep-sea concentrate; (b) providing a second agent, wherein the second agent The agent is a skin conditioning formula; (c) providing a fiber membrane, which is first infiltrated in the second agent and then in the first agent to form an infiltrating fiber membrane; (d) the infiltrating fiber membrane is immediately Apply on the surface of an affected area; (e) Apply an introducer on the infiltrated fiber membrane, the current applied by the introducer is 0.1mA~0.8mA per square centimeter, and the application time per square centimeter is 15-30 seconds: , Through the step (e), the first agent and the second agent can quickly penetrate the sebum membrane to reach the dermis, and stimulate collagen proliferation; wherein the magnesium concentration of the first agent is 6,500~110,000 mg/l Wherein, the hardness of the first agent is 80,000-420,000 mg/l, and the salinity is 380-430‰; the step d) the infiltrated fiber membrane is applied to the surface of the affected area within 10 minutes. According to the cosmetic method described in item 1 of the scope of patent application, according to the size of the fiber membrane, the usage amount of the second agent is 0.4 grams per square centimeter. According to the cosmetic method described in claim 1, wherein the effective concentration of the first agent in the infiltrated fiber membrane is at least greater than or equal to 1.25(v/v)%. According to the cosmetic method described in item 1 of the scope of patent application, wherein step e) applies the introducing instrument to the infiltrated fiber membrane within 10 minutes. As for the cosmetic method described in item 1 of the scope of patent application, the sodium concentration of the first dose is 3,800~30,000mg/l, the potassium concentration is 400~18,000mg/l, and the calcium concentration is 100~500mg/l. The cosmetic method as described in item 1 of the scope of patent application, wherein the first dose contains 1000~1500mg calcium, 1400~2100mg magnesium, 2000~4000mg sodium, 1400~2100mg potassium, sulfate <6.5wt per 100g %, and a specific gravity of 1.17~1.32g/cm3 of marine mineral solution. For the beauty method described in item 1 of the scope of patent application, the second agent is a whitening product, a moisturizing product, a wrinkle-removing beauty product, a beauty introduction product, and a beauty product that promotes collagen proliferation. According to the cosmetic method described in item 1 of the scope of patent application, the introduction device includes a power feeding device and a sensor. The power feeding device includes an outer surface and an interior; wherein the outer surface of the power feeding device includes: an operation The panel is arranged on one side of the aforementioned physical therapy device, so as to provide a control command to regulate a direct current output from the aforementioned power supply device. The aforementioned direct current is a combination of positive and negative electricity of different intensities and different time ratios; a sensor connection hole for Externally connected to the aforementioned sensor, the aforementioned sensor connection hole further has a stable current detection circuit, which is electrically connected to a control circuit and the aforementioned sensor connection hole for amplifying the voltage of a stimulation current; and a power input terminal, which is arranged in the aforementioned physical therapy instrument. On one side, in order to provide the aforementioned power supply device with a power supply, the aforementioned power supply input terminal further has a plurality of safety circuits, which are electrically connected The aforementioned control circuit and the aforementioned power input terminal are used to control the different voltages of the aforementioned power source; wherein the aforementioned power feeding device is equipped with the aforementioned control circuit, which is electrically connected to the aforementioned operation panel to obtain the aforementioned control commands and the aforementioned power input terminal to obtain the aforementioned power supply , And output the aforementioned direct current through the aforementioned sensor connection hole, including: a fixed and measured human body circuit to control the different intensities of the aforementioned direct current; and a switch valve circuit, selected by the aforementioned control command, to control the positive and negative of the aforementioned direct current; The aforementioned sensor refers to the aforementioned sensor connection hole of the aforementioned power supply device connected with a wire, which has a discharge terminal with a specific area interface, so that the aforementioned direct current outputs the aforementioned stimulation current through the aforementioned sensor.

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