TWI690299B - Non-invasive blood glucose testing machine system and method - Google Patents

Abstract

The invention is a non-invasive blood glucose testing machine system and method, which includes a casing, a control button unit, an input electrode unit, a signal filter, a signal converter, a control processor, a signal amplifier, an output electrode unit, a driver, a display unit and The battery unit is used to initially detect and display the user's blood glucose level (GLU) by non-invasive contact. Because the overall structure of the present invention is simple, there is no need to configure other devices or wires, it is very convenient to use, and it is very practical, which can assist the user to measure blood sugar, so it can avoid puncturing the finger too frequently to take out blood In order to prevent the risk of any potential bacterial infection, in particular, you can quickly measure anytime, anywhere, and provide a long-term monitoring function.

Description

Non-invasive blood glucose testing machine system and method

The invention relates to a non-invasive blood glucose testing machine system and method, in particular, a non-invasive contact method is used to initially detect and display a user's blood glucose value. The overall structure is simple and there is no need to configure other devices or wires. It is very convenient, and it is also very practical. It can help users measure blood sugar, avoid piercing their fingers too often to remove blood, and thereby prevent any potential risk of bacterial infection. Long-term monitoring.

As we all know, blood glucose refers to the glucose in the blood. Generally speaking, the glucose after food digestion enters the blood from the small intestine and is transported to each cell in the body. It is the main energy source of the cell. Therefore, the glucose content in the blood is The important physiological indicators of the human body are related to the absorption and metabolism of cells. The concentration of blood sugar in the human body is usually controlled within a very narrow range, such as 800-1200 mg/L.

Dysregulation of blood glucose concentration can cause a variety of diseases, such as high blood sugar and low blood sugar with persistently high blood sugar concentration. Usually, persistent high blood sugar will cause diabetes, which is also the most significant disease related to blood glucose concentration, and low blood sugar will cause dizziness, inability to concentrate or even shock.

For patients with diabetes, it is necessary to always pay attention to the blood sugar level, and inject insulin to reduce the blood sugar concentration, to avoid excessive blood sugar and affect the health of important organs of the body.

Traditionally, the measurement method of blood glucose value is to directly use a sampler to pierce the finger to collect blood, and then detect the blood glucose value by using appropriate medicine or detection equipment. Obviously, there is a risk of bacterial infections in wounds created by puncturing fingers, and the body's immunity will be affected under frequent finger punctures, thereby reducing the speed of wound healing.

Therefore, there is a great need for an innovative non-invasive blood glucose testing machine system and method, which uses a non-invasive contact method to initially detect and display the user's blood glucose level, in order to solve all the problems of the above-mentioned conventional techniques.

The main object of the present invention is to provide a non-invasive blood glucose testing machine system, which includes a housing, a control button unit, an input electrode unit, a signal filter, a signal converter, a control processor, a signal amplifier, an output electrode unit, a driver, and a display The unit and battery unit are used to initially detect and display the user's blood glucose level (GLU) by non-invasive contact.

Specifically, the housing has electrical insulation and waterproof functions, and has an accommodating space, and the control button unit is used for user operation to control the overall operation of the non-invasive blood glucose testing machine system.

In addition, the input electrode unit includes at least two input electrodes, is made of a conductive material, and has a sheet shape for contacting the user to receive an analog input signal. The signal filter is electrically connected to at least two input electrodes to receive the input signal and to generate and output a filtered signal after filtering processing, and the signal converter is electrically connected to the signal filter to receive the filtered signal and is analogized to The digital conversion signal is generated and output after the digital conversion processing.

Furthermore, the control processor is electrically connected to the signal converter to receive the converted signal, and to generate and output blood glucose information after the blood glucose calculation processing, and at the same time, perform the active excitation operation to generate and output the excitation signal, in particular, at least two inputs The input signal of the electrode is generated corresponding to the excitation driving signal, wherein the excitation signal is a square wave signal, and the frequency of the square wave signal is between 100 and 500 Hz.

In addition, the signal amplifier is electrically connected to the control processor for receiving the excitation signal, and generates and outputs the excitation amplification signal after being amplified. The output electrode unit includes at least two output electrodes for contacting the user, is made of conductive material, has a sheet shape, and is further electrically connected to the signal amplifier to receive the excitation amplification signal, thereby generating and outputting the excitation driving signal and transmitting to use By.

The above driver is electrically connected to the control processor for receiving blood glucose information and generating and outputting display driving signals, and the display unit is electrically connected to the driver for receiving display driving signals and displaying corresponding blood glucose information. In addition, the battery unit may include at least one battery for providing power to the control processor and the display unit to operate.

Further, the accommodating space of the housing can accommodate the control button unit, at least two input electrodes, at least two output electrodes, control processor, signal amplifier, signal filter, signal converter, driver, display unit and battery unit, and control The key unit, input electrode unit, output electrode unit and display unit are partially exposed on the upper or lower surface of the housing. In particular, the control processor, signal amplifier, signal filter, signal converter, driver and battery unit are The casing is covered and isolated from the outside of the casing to obtain insulation protection.

Furthermore, the control processor is electrically connected to the control button unit for selecting the operation mode according to the user operating the control button unit.

In addition, another object of the present invention is to provide a non-invasive blood glucose test method that initially detects and displays the user's blood glucose value by non-invasive contact and includes steps S1, S10, S20, S30, S40, S50, S60 and S70.

Step S1 starts after the input electrode unit is touched, and then waits for the waiting time, which is 0.6 to 1.2 seconds. In step S10, the input signals of at least two input electrodes are sampled; in step S20, an arithmetic average of every eight to twenty input signals is calculated to calculate an environmental average signal. Step S30, if the environmental average signal is greater than the noise threshold, then return to step S20, and if the environmental average signal is not greater than the noise threshold, the environmental average signal is the effective sensing signal, and the noise threshold is 300~500 Between real numbers.

Step S40, the effective sensing signal is divided into a first finger signal and a second finger signal, the first finger signal is from the first input electrode or the second input electrode in the input electrode unit that contacts the user's first finger, and The second finger signal is from the first input electrode or the second input electrode in the input electrode unit that is in contact with the user's second finger, the first finger is the thumb or index finger of the user's right hand and the second finger is the user's left hand The first finger is the left hand thumb or index finger and the second finger is the left hand thumb or index finger.

In step S50, the first finger signal is used to calculate the first finger feedback signal. The first finger feedback signal is A1_ratio, A1_ratio=P1*A1_m_ave+P2, P1 is the first parameter, P2 is the second parameter, and the first parameter is 0.05~ A real number of 0.08, the second parameter is a real number of 21.05~35.34, A1_m_ave is the average value of A1_m, A1_m is the remaining A1_ave of all A1_ave not greater than 600~1500, which is regarded as a stable feedback signal outside the extreme value range, A1_ave is An arithmetic average value is calculated for every ten first finger signals in succession, and the arithmetic average value is calculated 100 times in total.

Step S70, the first finger feedback signal and the second finger feedback signal are used to calculate the blood glucose value, and the blood glucose value is included in the blood glucose information, and the blood glucose value is GLU, GLU=P3*(A0_m_ave/P4)-P5)*( ((P6-A1_ratio)/10.238)-P5)*P7, P3 is the third parameter, P4 is the fourth parameter, P5 is the fifth parameter, P6 is the sixth parameter, P7 is the seventh parameter, the third parameter is normal The mode is 1, the real number is 1.1~1.2 in the prediabetes mode, and the real number is 1.8~2.2 in the diabetes mode, the fourth parameter is the real number 210~220 in the fasting mode, and is in the postprandial mode. The real number of 200~210, the fifth parameter is the real number of 0.03~0.06, the sixth parameter is the real number of 60~70 in fasting mode, and the real number of 71~80 in the postprandial mode, and the seventh parameter is ±3% ~15% percentage.

The non-invasive blood glucose testing machine system and method of the present invention provide a non-invasive contact method to initially detect and display the user's blood glucose value. Not only is the overall structure of the non-invasive blood glucose testing machine system of the present invention simple, no other devices are required Or lead, it is very convenient to use and very practical. It can help users measure blood sugar, avoid piercing their fingers too often to remove blood, and thus prevent any potential risk of bacterial infection, especially at any time. Measurement, and can monitor for a long time.

The embodiments of the present invention will be described in more detail below with reference to icons and component symbols, so that those skilled in the art can implement them after studying this specification.

Please refer to the first picture, the second picture and the third picture at the same time, wherein the first picture is a schematic diagram of the non-invasive blood glucose testing machine system of the first embodiment of the present invention, and the second picture is a top view of the non-invasive blood glucose testing machine system , And the third figure is a side view of the non-invasive blood glucose testing machine system. As shown in the first, second and third figures, the non-invasive blood glucose testing machine system of the present invention includes a housing 10, a control button unit 20, an input electrode unit 30, a signal filter 40, a signal converter 50, The control processor 60, the signal amplifier 70, the output electrode unit 80, the driver 90, the display unit 100, and the battery unit BU are used to initially detect and display the user's blood glucose level (GLU) by non-invasive contact.

Specifically, the housing 10 has electrical insulation and waterproof functions, and has an accommodating space for accommodating the control button unit 20, the input electrode unit 30, the signal filter 40, the signal converter 50, and the control processor 60 , Signal amplifier 70, output electrode unit 80, driver 90, display unit 100 and battery unit BU, in particular, the control button unit 20, input electrode unit 30, output electrode unit 80 and display unit 100 are partially exposed from the housing 10 The upper surface or the lower surface, and the control button unit 20, the signal filter 40, the signal converter 50, the control processor 60, the signal amplifier 70, the driver 90 and the battery unit BU are covered by the housing 10 and External isolation.

In addition, the control button unit 20 is used by the user to control the operation of the non-invasive blood glucose testing machine system of the present invention. The input electrode unit 30 includes at least two input electrodes, such as the first input electrode 31 and the second input electrode 32, which are made of a conductive material and have a sheet shape for contacting the user to receive an analog input signal. The signal filter 40 is electrically connected to the input electrode unit 30 to receive the input signal, and is filtered to generate and output a filtered signal, and the signal converter 50 is electrically connected to the signal filter 40 to receive the filtered signal and be analogized The digital-to-digital conversion (analog-to-digital conversion, ADC) generates and outputs digital conversion signals.

Furthermore, the control processor 60 is electrically connected to the signal converter 50 to receive the converted signal, and to generate and output blood glucose information after the blood glucose calculation processing, and simultaneously execute the active excitation operation to generate and output the excitation signal, and input the electrode unit 30 The input signal received from the user is generated corresponding to the excitation driving signal, where the excitation signal is a square wave signal, and the frequency of the square wave signal is between 100 and 500 Hz.

In addition, the signal amplifier 70 is electrically connected to the control processor 60 for receiving the excitation signal and generating and outputting the excitation amplification signal after being amplified, and the output electrode unit 80 includes at least two output electrodes, such as the first output electrode 81 and the third The two output electrodes 82 are used to contact the user, are made of a conductive material, and have a sheet shape, and are electrically connected to the signal amplifier 70 to receive the excitation amplification signal to generate and output an excitation driving signal to be transmitted to the user.

In addition, the driver 90 is electrically connected to the control processor 60 for receiving blood glucose information, and generating and outputting display driving signals, and the display unit 100 is electrically connected to the driver 90, receiving display driving signals, and displaying blood glucose information. Further, the battery unit BU includes at least one battery BT for providing power to the control processor 60 and the display unit 100 to operate.

Furthermore, the control processor 60 is electrically connected to the control button unit 20 for selecting the corresponding operation mode according to the user operating the control button unit 20.

The above control button unit 20 includes at least one of a power button 21, an up mode selection button 22, a down mode selection button 23, and a confirmation button 24, wherein the power button 21 is used to turn on or off the power of the battery unit BU To supply or stop supplying power, the up mode selection button 22 and the down mode selection button 23 are used to select the required operation mode up and down, and the confirm button 24 is used for user confirmation. Furthermore, the operation mode may include a fasting mode, a postprandial mode, a normal mode, a pre-diabetes mode, and a diabetes mode.

Further, the first output electrode 81 of the output electrode unit 80 has a hollow ring shape, and the second input electrode 82 has a half-moon shape, and is located within the hollow ring shape of the first output electrode 81. In addition, the first input electrode 31 of the input electrode unit 30 has a half-moon shape and is located within the hollow ring shape of the first output electrode 81 and does not contact the second input electrode 32, wherein the second input electrode 32 has a hollow ring shape, a right The half-moon shape and the left half-moon shape, and the right half-moon shape and the left half-moon shape are in the shape of a hollow ring at the second input electrode 32.

In addition, the size of the hollow ring shape of the first output electrode 31 and the size of the hollow ring shape of the second input electrode 32 are equal to or greater than the contact area of the user's finger touching the input electrode unit 30 or the output electrode unit 80 .

As shown in the third diagram, the input/output electrode unit 30 and the output electrode unit 80 may be disposed on the upper surface or the lower surface of the housing 10. For example, the user presses the thumb or index finger of both hands on the upper or lower surface of the non-invasive blood glucose testing machine system of the present invention, and thus simultaneously contacts the input/output electrode unit 30 and the output electrode unit 80.

Therefore, the non-invasive blood glucose testing machine system of the first embodiment of the present invention is easy to operate and use, as long as the user touches the input and output electrode unit 30 and the output electrode unit 80 with a finger, the control processor 60 can actively perform the blood glucose value Detection, while displaying blood glucose. Furthermore, the overall structure of the non-invasive blood glucose testing machine system of the present invention is simple, and is essentially a rectangular box, without the need to configure other devices or wires, which is very convenient to use.

With further reference to the fourth figure, a flowchart of a non-invasive blood glucose testing method according to a second embodiment of the present invention. As shown in the fourth figure, the non-invasive blood glucose testing method of the present invention includes steps S1, S10, S20, S30, S40, S50, S60, and S70, which use the non-invasive blood glucose testing machine system described above instead of invasive contact Initially detect and display the user's blood glucose level (GLU).

Since the technology of the non-invasive blood glucose testing machine system has been described, it will not be described in detail below.

The non-invasive blood glucose test method of the present invention is implemented by the control processor 60. Step S1 is first performed after the input electrode unit is touched. The control processor 60 generates and outputs a frequency of 100 and 100 by performing an active excitation operation. The excitation signal between 500 Hz is transmitted to the user through the signal amplifier 70 and the output electrode unit 80, and the input electrode unit 30 receives the input signal generated from the user corresponding to the excitation driving signal and passes through the signal filter 40. The signal converter 50 is received by the control processor 60, and then waits for a preset waiting time, where the waiting time may be 0.6 to 1.2 seconds.

After that, proceed to step S10 to sample the input signal from the input electrode unit, and the sampling may be performed once in at least one cycle of the excitation signal, preferably, once in each cycle of the excitation signal. Next, in step S20, every eight to twenty input signals are arithmetically averaged to calculate the environmental average signal, and in step S30, it is determined whether the environmental average signal is greater than the preset noise threshold, where the noise The signal threshold is a real number between 300 and 500. If the average signal of the environment is greater than the noise threshold, return to step S20. If the average signal of the environment is not greater than the noise threshold, the average signal of the environment is the effective sensing signal. And go to step S40.

In step S40, the effective sensing signal is divided into a first finger signal and a second finger signal, wherein the first finger signal is from the first input electrode or the second input of the input electrode unit that contacts the user's first finger Electrodes, and the second finger signal comes from the first input electrode or the second input electrode in the input electrode unit that is in contact with the second finger of the user. For example, the first finger may be the thumb or index finger of the user's right hand, and the second finger may be the thumb or index finger of the user's left hand, or the first finger may be the thumb or index finger of the left hand, and the second finger is The thumb or index finger of the left hand.

After that, step S50 is executed to calculate the first finger feedback signal using the first finger signal, and the first finger feedback signal is A1_ratio, where A1_ratio=P1*A1_m_ave+P2, P1 is the first parameter, and P2 is the second parameter, the second One parameter is a real number of 0.05~0.08, the second parameter is a real number of 21.05~35.34, A1_m_ave is the average value of A1_m, A1_m is the remaining A1_ave of all A1_ave not greater than 600~1500, which is considered to be outside the extreme value range To stabilize the feedback signal, A1_ave is the arithmetic average value calculated every 10 first finger signals continuously, and the arithmetic average value is calculated 100 times in total.

Next, in step S60, the second finger signal is used to calculate the second finger feedback signal, and the second finger feedback signal is A2_m_ave, where A2_m_ave is the average value of A2_m, and A2_m is the remaining A2_ave of all A2_ave not greater than 1200~1800 , As a stable feedback signal outside the extreme value range, A2_ave is the arithmetic average value calculated every 10 second finger signals continuously, and the arithmetic average value is calculated 100 times in total.

Finally, go to step S70, use the first finger feedback signal and the second finger feedback signal to calculate the blood glucose value, and include the blood glucose value in the blood glucose information, and the blood glucose value is GLU, where GLU=P3*(A0_m_ave/P4)-P5 )*(((P6-A1_ratio)/10.238)-P5)*P7, P3 is the third parameter, P4 is the fourth parameter, P5 is the fifth parameter, P6 is the sixth parameter, and P7 is the seventh parameter. Specifically, the third parameter is 1 in normal mode, 1.1 to 1.2 real number in pre-diabetes mode, and 1.8 to 2.2 real number in diabetes mode; the fourth parameter is 210 to 220 in fasting mode Real number, and real number of 200~210 in postprandial mode; fifth parameter is real number of 0.03~0.06; sixth parameter is real number of 60~70 in fasting mode, and 71~80 in postprandial mode Real number; the seventh parameter is a percentage of ±3%~15%.

In other words, the non-invasive blood glucose test method of the second embodiment of the present invention uses the user's feedback signal corresponding to the excitation signal to obtain a relatively accurate blood glucose value through a specific calculation method.

To further show the comparison results of the blood glucose values detected by the traditional blood-binding method and the method of the present invention, reference may be made to the fifth figure, which shows the blood glucose values of four users of different ages on an empty stomach and after a meal. Obviously, the blood glucose value detected by the method of the present invention is quite accurate, and the error is within -12.4% to +12.8%. Therefore, the present invention is very practical, can assist users to measure blood sugar, avoid piercing fingers too frequently to take out blood, and thereby prevent any potential risk of bacterial infection, especially for rapid measurement at any time, and can Long-term monitoring.

The above are only for explaining the preferred embodiments of the present invention, and are not intended to limit the present invention in any form, so that any modifications or changes made to the present invention under the same spirit of the invention , Should still be included in the scope of protection of the present invention.

10: Shell 20: Control button unit 30: Input electrode unit 31: The first input electrode 32: Second input electrode 40: Signal filter 50: signal converter 60: control processor 70: signal amplifier 80: output electrode unit 81: first output electrode 82: second output electrode 90: drive 100: display unit BU: battery unit BT: battery S1: Step S10, S20, S30, S40: steps S50, S60, S70: steps

The first figure shows a schematic diagram of a non-invasive blood glucose testing machine system according to a first embodiment of the present invention. The second figure shows a top view of the non-invasive blood glucose testing machine system according to the first embodiment of the present invention. The third figure shows a side view of the non-invasive blood glucose testing machine system according to the first embodiment of the present invention. The fourth figure shows a flowchart of a non-invasive blood glucose testing method according to a second embodiment of the present invention. The fifth graph shows the comparison results of the blood glucose values measured by the traditional blood-binding method and the method of the present invention.

10: Shell

20: Control button unit

30: Input electrode unit

31: The first input electrode

32: Second input electrode

40: Signal filter

50: signal converter

60: control processor

70: signal amplifier

80: output electrode unit

81: first output electrode

82: second output electrode

90: drive

100: display unit

BU: battery unit

BT: battery

Claims (8)

A non-invasive blood glucose testing machine system is used to initially detect and display a user's blood glucose value by a non-invasive contact method, including: A shell, with electrical insulation and waterproof function, and a containing space; A control button unit for the user to control the operation of the non-invasive blood glucose testing machine system; An input electrode unit, comprising at least two input electrodes, is made of conductive material and has a sheet shape for contacting the user to receive an analog input signal; A signal filter, electrically connected to the at least two input electrodes, for receiving the input signal, and generating and outputting a filtered signal after a filtering process; A signal converter is electrically connected to the signal filter for receiving the filtered signal and generating and outputting a digital conversion signal after an analog-to-digital conversion (ADC); A control processor is electrically connected to the signal converter to receive the converted signal, and generates and outputs a blood glucose information after a blood glucose calculation process, and simultaneously performs an active excitation operation to generate and output an excitation signal, And the input signal of the at least two input electrodes is generated corresponding to the excitation driving signal, the excitation signal is a square wave signal, and a frequency of the square wave signal is between 100 and 500 Hz; A signal amplifier is electrically connected to the control processor for receiving the excitation signal, and generates and outputs an excitation amplification signal after an amplification process; An output electrode unit includes at least two output electrodes for contacting the user, is composed of a conductive material, and has a sheet shape, and is electrically connected to the signal amplifier to receive the excitation amplification signal to generate and output A drive signal is sent to the user; A driver is electrically connected to the control processor for receiving the blood glucose information, and generating and outputting a display driving signal; A display unit electrically connected to the driver, receiving the display driving signal, and displaying the corresponding blood glucose information; and A battery unit including at least one battery for providing power to the control processor and the display unit to operate, The accommodating space of the housing accommodates the control button unit, the input electrode unit, the signal amplifier, the signal filter, the signal converter, the control processor, the output electrode unit, the driver, and the display unit And the battery unit, and the control button unit, the input electrode unit, the output electrode unit and the display unit are partially exposed on an upper surface or a lower surface of the casing, the control processor, the signal amplifier, the The signal filter, the signal converter, the driver and the battery unit are covered by the casing and isolated from the outside of the casing, and the control processor is electrically connected to the control button unit to be used according to the user Operate the control button unit to select an operation mode. The non-invasive blood glucose testing machine system according to item 1 of the patent application scope, wherein the control button unit includes at least one of a power button, an up mode selection button, a down mode selection button, and a confirmation button , The power button is used to turn on or off the power supply of the battery unit to supply or stop the power supply, the up mode selection button and the down mode selection button are used to select the operation mode up and down, and the The confirmation key is for the user to confirm, and the operation mode includes a fasting mode, a postprandial mode, a normal mode, a pre-diabetes mode and a diabetes mode. The non-invasive blood glucose testing machine system according to item 1 of the patent application scope, wherein at least two output electrodes of the output electrode unit include a first output electrode and a second output electrode, the first output electrode having a hollow ring Shape, the second input electrode has a half-moon shape, and is located in a hollow ring shape of the first output electrode, at least two input electrodes of the input electrode unit include a first input electrode and a second input electrode, the first The input electrode has a half-moon shape, and is located in the hollow ring shape of the first output electrode, and does not contact the second input electrode, the second input electrode has a hollow ring shape, a right half moon shape, and a left half moon shape, And the right half-moon shape and the left half-moon shape are located in a hollow ring shape of the second input electrode, a size of the hollow ring shape of the first output electrode and a size of the hollow ring shape of the second input electrode It is equal to or greater than a contact area where a finger of the user contacts the input electrode unit or the output electrode unit. A non-invasive blood glucose test method is realized by using a control processor, and the control processor is matched with a casing, a control button unit, an input electrode unit, a signal filter, a signal converter, and a signal An amplifier, an output electrode unit, a driver, a display unit, and a battery unit, the housing accommodates the control button unit, the input electrode unit, the control processor, the signal amplifier, the signal filter, the signal conversion Device, the output electrode unit, the driver, the display unit, and the battery unit, and the non-invasive blood glucose test method includes: A step S1, which starts after the input electrode unit is touched, and then waits for a waiting time, wherein the input electrode unit includes at least two input electrodes for contacting a user to receive an analog input signal, and the at least The two input electrodes include a first input electrode and a second input electrode, the signal filter is electrically connected to the input electrode unit to receive the input signal, and after filtering processing to generate and output a filtered signal, the signal converter is electrically Connected to the signal filter to receive the filtered signal and generate and output a digital conversion signal after an analog-to-digital conversion process (ADC), the control processor is electrically connected to the signal converter to receive the conversion signal, and A blood glucose information is generated and output after a blood glucose calculation process, and an active excitation operation is performed to generate and output an excitation signal, and the input signal is generated corresponding to the excitation driving signal, and the signal amplifier is electrically connected to the control The processor receives the excitation signal and generates and outputs an excitation amplification signal after an amplification process. The output electrode unit includes at least two output electrodes, and the at least two output electrodes include a first output electrode and a second output An electrode is used to contact the user, and is electrically connected to the signal amplifier to receive the excitation amplification signal to generate and output an excitation drive signal to be transmitted to the user, and the driver is electrically connected to the control processor to receive the Blood glucose information, and generates and outputs a display drive signal, the display unit is electrically connected to the driver, receives the display drive signal, and displays the corresponding blood glucose information, the battery unit includes at least one battery for providing power to the The control processor and the display unit operate. The control processor is further electrically connected to the control button unit to select an operation mode according to the user operating the control button unit. The operation mode includes an empty stomach mode and a postprandial mode , A normal model, a pre-diabetes model and a diabetic model; A step S10, sampling the input signals of the at least two input electrodes; A step S20, arithmetically averaging every eight to twenty input signals to calculate an environmental average signal; In step S30, if the environmental average signal is greater than a noise threshold, then return to step S20, and if the environmental average signal is not greater than a noise threshold, the environmental average signal is an effective sensing signal, and The noise threshold is a real number between 300~500; In a step S40, the effective sensing signal is divided into a first finger signal and a second finger signal, the first finger signal is from the first input of the input electrode unit that contacts the first finger of the user Electrode or the second input electrode, and the second finger signal is from the first input electrode or the second input electrode in the input electrode unit that is in contact with a second finger of the user, the first finger is the A thumb or an index finger of the right hand of one of the users and the second finger is a thumb or an index finger of the left hand of the user, or the first finger is the thumb or the index finger of the left hand and the second finger The thumb or index finger of the left hand; In step S50, the first finger signal is used to calculate a first finger feedback signal, the first finger feedback signal is A1_ratio, A1_ratio=P1*A1_m_ave+P2, P1 is a first parameter, and P2 is a second parameter, The first parameter is a real number of 0.05~0.08, the second parameter is a real number of 21.05~35.34, A1_m_ave is an average value of A1_m, A1_m is the remaining A1_ave of all A1_ave not greater than 600~1500, which is regarded as an extreme A stable feedback signal outside the range of values, A1_ave is an arithmetic average calculated every 10 consecutive first finger signals, and the arithmetic average is calculated a total of 100 times; In step S60, the second finger signal is used to calculate a second finger feedback signal, the second finger feedback signal is A2_m_ave, A2_m_ave is an average value of A2_m, and A2_m is the remaining A2_ave of all A2_ave not greater than 1200~1800, Regarded as a stable feedback signal outside an extreme value range, A2_ave is an arithmetic average calculated every 10 consecutive second finger signals, and the arithmetic average is calculated 100 times in total; and In step S70, the first finger feedback signal and the second finger feedback signal are used to calculate the blood glucose value, and the blood glucose value is included in the blood glucose information, and the blood glucose value is GLU, GLU=P3*(A0_m_ave/ P4)-P5)*(((P6-A1_ratio)/10.238)-P5)*P7, P3 is a third parameter, P4 is a fourth parameter, P5 is a fifth parameter, P6 is a sixth parameter, P7 is a seventh parameter, the third parameter is 1 in the normal mode, the real number is 1.1~1.2 in the pre-diabetes mode, and the real number is 1.8~2.2 in the diabetes mode, the fourth parameter is The fast mode is a real number of 210-220, and the postprandial mode is a real number of 200-210, the fifth parameter is a real number of 0.03-0.06, and the sixth parameter is 60-70 of the fasting mode Real number, and in the postprandial mode is a real number of 71~80, the seventh parameter is a percentage of ± 3% ~ 15%. According to the non-invasive blood glucose test method described in item 4 of the patent application scope, the waiting time is 0.6 to 1.2 seconds. According to the non-invasive blood glucose testing method described in item 4 of the patent application scope, wherein the excitation signal is a square wave signal, and a frequency of the square wave signal is between 100 and 500 Hz. According to the non-invasive blood glucose test method described in item 4 of the patent application scope, wherein the control button unit includes at least one of a power button, an up-shift mode selection button, a down-shift mode selection button, and a confirmation button, The power button is used to turn on or off the power supply of the battery unit to supply or stop the power supply, the up mode selection button and the down mode selection button are used to select the operation mode up and down, and the confirmation The key is for the user to confirm. The non-invasive blood glucose test method according to item 4 of the patent application scope, wherein at least two output electrodes of the output electrode unit include a first output electrode and a second output electrode, the first output electrode has a hollow ring shape , The second input electrode has a half-moon shape and is located in the hollow ring shape of the first output electrode, at least two input electrodes of the input electrode unit include a first input electrode and a second input electrode, the first input The electrode has a half-moon shape, and is located in the hollow ring shape of the first output electrode, and does not contact the second input electrode, the second input electrode has a hollow ring shape, a right half moon shape, and a left half moon shape, and The right half-moon shape and the left half-moon shape are located in the hollow ring shape of the second input electrode, a size of the hollow ring shape of the first output electrode and a size of the hollow ring shape of the second input electrode are A contact area equal to or greater than a finger of the user touching the input electrode unit or the output electrode unit.

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