TWI597515B - Parameter setting method of ultrasonic transducer - Google Patents
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Description
本發明是有關於一種超音波探頭,且特別是有關於一種超音波探頭的參數設定方法。 The present invention relates to an ultrasonic probe, and more particularly to a parameter setting method for an ultrasonic probe.
在超音波聲學影像(acoustical images)中,常使用空間複合(spatial compounding)方法或頻率複合(frequency compounding)方法進行預掃描。其中,空間複合方法係藉由從不同角度擷取相同目標物體之多個影像而達成,而頻率複合方法係藉由在不同頻率範圍內擷取相同目標物體之多個影像而達成。 In ultrasonic acoustic images, a spatial compounding method or a frequency compounding method is often used for pre-scanning. The spatial composite method is achieved by capturing multiple images of the same target object from different angles, and the frequency composite method is achieved by capturing multiple images of the same target object in different frequency ranges.
然而,以空間複合方法而言,空間解析度將因從不同角度測量目標物體所增加之光束尺寸而被降低。同樣地,在頻率複合方法中,空間解析度將因脈波變長所產生之頻寬而被降低。因此,單純以空間複合方法或頻率複合方法所得到的複合影像,由於斑點(speckle)的出現而嚴重地降低對比解析能力,也無法針對當下超音波探頭所使用的頻率或角度進行改變或調整,以至於無法調整到最佳的成像品質。 However, in the spatial composite approach, the spatial resolution will be reduced by measuring the beam size increased by the target object from different angles. Similarly, in the frequency recombination method, the spatial resolution is reduced by the bandwidth generated by the pulse length becoming longer. Therefore, the composite image obtained by simply using the spatial composite method or the frequency composite method severely reduces the contrast analysis ability due to the appearance of speckle, and cannot change or adjust the frequency or angle used by the current ultrasonic probe. It is impossible to adjust to the best image quality.
本發明係有關於一種超音波探頭的參數設定方法,可先針對不同頻率範圍內或不同角度範圍內非相關性大的超音波影像進行匹配,再進行預先合圖,並針對複合影像中的光斑尺寸進行判斷,以找出超音波探頭的一最適化參數設定值。 The invention relates to a parameter setting method for an ultrasonic probe, which can first match an uncorrelated ultrasonic image with different frequency range or different angle ranges, and then perform pre-combination and aim for a spot in the composite image. The size is judged to find an optimum parameter setting value of the ultrasonic probe.
根據本發明之一方面,提出一種超音波探頭的參數設定方法,包括下列步驟。由一超音波探頭發射多組超音波,並接收各組超音波的回波訊號,其中各組超音波分別具有不同發射頻率。將多組超音波的回波訊號轉換為多個數位化超音波影像。針對此些數位化超音波影像中兩兩影像預合成為多個超音波複合影像,上述兩兩影像的非相關性匹配值大於一預定值。由此些超音波複合影像中比對出光斑尺寸最小且非相關性數值大於第一設定值的一最適化影像,並以最適化影像所對應的一發射頻率做為超音波探頭的一最適化參數設定值。 According to an aspect of the invention, a parameter setting method of an ultrasonic probe is provided, which comprises the following steps. A plurality of ultrasonic waves are emitted by an ultrasonic probe, and echo signals of each group of ultrasonic waves are received, wherein each group of ultrasonic waves has different transmission frequencies. Converting echo signals of multiple sets of ultrasonic waves into multiple digitalized ultrasonic images. For the digitalized ultrasonic images, the two images are pre-combined into a plurality of ultrasonic composite images, and the non-correlation matching values of the two images are greater than a predetermined value. In the supersonic composite image, an optimized image with the smallest spot size and the non-correlation value greater than the first set value is compared, and an emission frequency corresponding to the optimized image is used as an optimization of the ultrasonic probe. Parameter setting value.
為了對本發明之上述及其他方面有更佳的瞭解,下文特舉較佳實施例,並配合所附圖式,作詳細說明如下: In order to better understand the above and other aspects of the present invention, the preferred embodiments are described below, and in conjunction with the drawings, the detailed description is as follows:
M1、M2‧‧‧超音波影像 M1, M2‧‧‧ ultrasound image
C1、C2‧‧‧曲線 C1, C2‧‧‧ curve
AP‧‧‧交叉點 AP‧‧‧ intersection
SE‧‧‧最適化參數設定值 SE‧‧‧Optimized parameter setting
S10~S15‧‧‧各個步驟 S10~S15‧‧‧Steps
第1圖繪示繪示依照本發明一實施例之超音波探頭的參數設定方法的流程圖。 FIG. 1 is a flow chart showing a method for setting parameters of an ultrasonic probe according to an embodiment of the invention.
第2圖繪示相關性係數與對應之深度的曲線圖。 Figure 2 is a graph showing the correlation coefficient and the corresponding depth.
第3圖繪示最適化影像的判斷參考圖。 Figure 3 is a diagram showing the judgment reference of the optimized image.
在本實施例之一範例中,提出一種超音波探頭的參數設定方法。超音波探頭例如是線性陣列的探頭、相位陣列的探 頭或其他型態的探頭。超音波探頭包含多個超音波陣元,每一個超音波陣元為一個轉能器,用以將高頻脈衝產生器輸出的脈衝電壓訊號,轉換成機械震盪的超音波,而傳送入組織內部。接著,各個超音波陣元再接收組織內部散射子反射的回波訊號,並轉換成脈衝電壓訊號,以得到一組掃描訊號。當超音波入射波長遠大於組織內部散射子的直徑時,會發生超音波的散射現象,而逆散射訊號會在B-mode影像中出現隨機明暗斑狀的亮點,這就是所謂的光斑(speckle)。光斑的存在模糊了細微構造的影像,降低了超音波影像的對比度與解析度。 In an example of the embodiment, a parameter setting method of the ultrasonic probe is proposed. Ultrasonic probes such as linear array probes, phase arrays Head or other type of probe. The ultrasonic probe comprises a plurality of ultrasonic array elements, and each ultrasonic array element is a transducer for converting the pulse voltage signal outputted by the high-frequency pulse generator into a mechanically oscillated ultrasonic wave and transmitting it into the tissue. . Then, each of the ultrasonic array elements receives the echo signals reflected by the internal scattering elements and converts them into pulse voltage signals to obtain a set of scanning signals. When the incident wavelength of the ultrasonic wave is much larger than the diameter of the scatterer inside the tissue, ultrasonic scattering occurs, and the reverse scatter signal will appear randomly bright spots in the B-mode image. This is called speckle. . The presence of the flare blurs the fine-grained image, reducing the contrast and resolution of the ultrasound image.
本實施例可對任何形式的超音波探頭進行最適化參數設定,根據超音波的回波訊號評估超音波影像的相關性,找出非相關性大的超音波影像,接著,根據空間複合(spatial compounding)方法或頻率複合(frequency compounding)方法進行預先合圖,再根據超音波複合影像進行比對分析,以判斷非相關性大於第一設定值所對應的超音波複合影像的光斑尺寸大小或直方圖的面積。如此,可從此些超音波複合影像中比對出最適化影像,並以最適化影像的發射頻率或發射角度做為超音波探頭的一最適化參數設定值。 In this embodiment, the optimal parameter setting can be performed on any type of ultrasonic probe, the correlation of the ultrasonic image is evaluated according to the echo signal of the ultrasonic wave, and the uncorrelated ultrasonic image is found, and then, according to the spatial composite (spatial) The compounding method or the frequency compounding method performs pre-combination, and then performs an alignment analysis based on the ultrasonic composite image to determine the spot size or the histogram of the ultrasonic composite image corresponding to the non-correlation greater than the first set value. The area of the map. In this way, the optimized image can be compared from the supersonic composite images, and the transmission frequency or the emission angle of the optimized image is used as an optimum parameter setting value of the ultrasonic probe.
以下係提出實施例進行詳細說明,實施例僅用以作為範例說明,並非用以限縮本發明欲保護之範圍。 The embodiments are described in detail below, and the embodiments are only intended to be illustrative and not intended to limit the scope of the invention.
請參照第1圖,其繪示依照本發明一實施例之超音波探頭的參數設定方法的流程圖。首先,在步驟S10中,由一超音波探頭發射多組超音波,並接收各組超音波的回波訊號,其中各組超音波分別具有不同發射頻率或具有不同的發射角度。在一 實施例中,當組織內部的散射子位在深度6公分以內的區間時,超音波探頭以可用掃描頻段的40%至90%內的多組超音波進行預掃描,以找出適合上述深度區間在6公分以內的中心頻率。在另一實施例中,當組織內部的散射子所在的深度區間超過6公分時,超音波探頭以可用掃描頻段的10%至60%內的多組超音波進行預掃描,以找出適合上述深度區間超過6公分的中心頻率。在另一實施例中,超音波探頭例如以介於超音波探頭之零度發射角的-20度至20度區間內的多組超音波進行預掃描,以找出適合的發射角度。 Please refer to FIG. 1 , which is a flow chart of a method for setting parameters of an ultrasonic probe according to an embodiment of the invention. First, in step S10, a plurality of sets of ultrasonic waves are emitted by an ultrasonic probe, and echo signals of each group of ultrasonic waves are received, wherein each group of ultrasonic waves respectively have different transmission frequencies or have different emission angles. In a In an embodiment, when the scattering sub-location within the tissue is within a depth of 6 cm, the ultrasonic probe is pre-scanned with a plurality of sets of ultrasonic waves within 40% to 90% of the available scanning frequency band to find a suitable depth interval. The center frequency is within 6 cm. In another embodiment, when the depth range of the scatterers inside the tissue is more than 6 cm, the ultrasonic probe is pre-scanned with a plurality of sets of ultrasonic waves within 10% to 60% of the available scanning frequency band to find the above suitable The center frequency of the depth interval exceeding 6 cm. In another embodiment, the ultrasonic probe is pre-scanned, for example, with a plurality of sets of ultrasonic waves in the range of -20 degrees to 20 degrees of the zero-degree emission angle of the ultrasonic probe to find a suitable emission angle.
一般而言,探頭的性能例如脈衝訊號的發射角度及中心頻率等參數,在進行掃描時,會設定固定的發射頻率或固定的發射角度,無法針對當下超音波探頭所使用的頻率或角度進行改變或調整。本發明提出一種自適應性複合影像超音波,可針對超音波探頭所使用的頻率或角度進行改變或調整,請參照步驟S11~S15。 In general, the performance of the probe, such as the emission angle of the pulse signal and the center frequency, will set a fixed transmission frequency or a fixed emission angle when scanning, and cannot be changed for the frequency or angle used by the current ultrasonic probe. Or adjust. The invention provides an adaptive composite image ultrasonic wave, which can be changed or adjusted for the frequency or angle used by the ultrasonic probe, please refer to steps S11~S15.
在步驟S11中,將多組超音波的回波訊號轉換為多個數位化超音波影像,以利於比對分析。接著,在步驟S12中,針對此些數位化超音波影像中兩兩影像之間的非相關性進行匹配,以評估非相關性匹配值是否大於一預定值。也就是說,針對兩個不同發射頻率或兩個不同發射角度所產生的超音波影像進行非相關性分析。當非相關性越大時,表示兩個影像之間差異性越大,但是為了避免取到非相關性極大值的兩個影像,還需進一步考量光斑尺寸大小,才能決定最適化參數設定值。 In step S11, the echo signals of the plurality of sets of ultrasonic waves are converted into a plurality of digitalized ultrasonic images to facilitate the comparison analysis. Next, in step S12, a non-correlation between the two images in the digitized ultrasonic images is matched to evaluate whether the non-correlation matching value is greater than a predetermined value. That is to say, the non-correlation analysis is performed on the ultrasonic images generated by two different transmission frequencies or two different emission angles. When the non-correlation is larger, it means that the difference between the two images is larger, but in order to avoid taking two images with non-correlation maxima, it is necessary to further consider the spot size to determine the optimal parameter setting value.
在步驟S12中,非相關性匹配步驟例如自此些數位 化超音波影像中選取一張數位化超音波影像做為匹配基準的一參考影像,或是以此些數位化超音波影像兩兩相互比較。在一實施例中,當以超音波探頭的中心頻率為匹配基準時,上述做為匹配基準的參考影像可為對應超音波探頭之中心頻率所產生的數位化超音波影像。 In step S12, the non-correlation matching step is, for example, from such digits In the ultrasound image, a digital ultrasound image is selected as a reference image for matching the reference, or the digital ultrasound images are compared with each other. In an embodiment, when the center frequency of the ultrasonic probe is used as a matching reference, the reference image used as the matching reference may be a digitalized ultrasonic image generated corresponding to the center frequency of the ultrasonic probe.
在另一實施例中,當以超音波探頭之零度發射角為匹配基準時,上述做為匹配基準的參考影像可為對應超音波探頭之零度發射角所產生的數位化超音波影像。 In another embodiment, when the zero-degree emission angle of the ultrasonic probe is used as a matching reference, the reference image used as the matching reference may be a digitalized ultrasonic image generated corresponding to the zero-degree emission angle of the ultrasonic probe.
請參照第2圖,其繪示相關性係數與對應之深度的曲線圖。在第2圖中,兩個超音波影像M1、M2在深度區間小於4公分,相關性係數大於0.8時,表示兩個超音波影像M1、M2之間的差異性在預定值內;當深度區間界於6-10公分,相關性係數小於0.5時,表示兩個超音波影像M1、M2之間差異性已超出預定值。因此,在第2圖中,當第一設定值為0.5時,可選取深度區間界於6-10公分做為非相關性大於第一設定值所對應的深度區間。 Please refer to FIG. 2, which is a graph showing the correlation coefficient and the corresponding depth. In Fig. 2, the two ultrasonic images M1 and M2 are less than 4 cm in the depth interval, and the correlation coefficient is greater than 0.8, indicating that the difference between the two ultrasonic images M1 and M2 is within a predetermined value; When the correlation coefficient is less than 0.5, it means that the difference between the two ultrasonic images M1 and M2 has exceeded the predetermined value. Therefore, in FIG. 2, when the first set value is 0.5, the depth interval boundary may be selected as 6-10 cm as the depth interval corresponding to the non-correlation greater than the first set value.
接著,步驟S13,將此些數位化超音波影像中兩兩影像預合成為多個超音波複合影像,上述兩兩影像的非相關性匹配值大於一預定值(例如大於0.5或更小),並針此些超音波複合影像進行比對分析。也就是說,將兩兩不同發射頻率或兩兩不同發射角度所產生的影像預先複合(pre-compounding)而形成多個超音波複合影像,並對此些超音波複合影像進行比對,以判斷各個超音波複合影像的光斑尺寸大小。 Next, in step S13, the two images in the digitalized ultrasonic images are pre-combined into a plurality of ultrasonic composite images, and the non-correlation matching values of the two images are greater than a predetermined value (for example, greater than 0.5 or less). And these supersonic composite images were compared for analysis. That is to say, two or two different emission frequencies or two different two different emission angles are pre-compounded to form a plurality of ultrasonic composite images, and the ultrasonic composite images are compared to determine The size of the spot size of each ultrasonic composite image.
在一實施例中,超音波影像的發射頻率例如為 6.5MHz、7.5MHz以及8.5MHz,將此三個不同發射頻率所產生的超音波影像兩兩進行匹配,以形成三組超音波影像並預合成為三組超音波複合影像,再將此些超音波複合影像進行比對,以判斷各個超音波複合影像的光斑尺寸大小。 In an embodiment, the transmission frequency of the ultrasonic image is, for example, 6.5MHz, 7.5MHz and 8.5MHz, the ultrasonic images generated by the three different transmission frequencies are matched two by two to form three sets of ultrasonic images and pre-synthesized into three sets of ultrasonic composite images, and then these super The sound wave composite images are compared to determine the spot size of each ultrasonic composite image.
在一實施例中,上述比對分析步驟例如以各個超音波複合影像的像素灰度差的絕對值和(Sum of absolute differences,SAD),來計算光斑尺寸大小。當像素灰度差的絕對值和的數值越大,表示光斑尺寸越大,反之,則越小。上述的光斑尺寸大小例如以直方圖表示,當直方圖的面積越大,表示像素灰度差的平方和的數值越大,反之,則越小。 In one embodiment, the alignment analysis step calculates the spot size by, for example, the Sum of absolute differences (SAD) of the pixel grayscale differences of the respective ultrasonic composite images. When the absolute value of the pixel gradation difference is larger, it means that the spot size is larger, and conversely, the smaller. The above-described spot size is represented, for example, by a histogram. When the area of the histogram is larger, the numerical value indicating the square sum of the pixel gradation differences is larger, and conversely, the smaller is smaller.
在一實施例中,上述比對分析步驟例如以各個超音波複合影像的像素灰度差的平方和(Sum of squared differences,SSD),來計算光斑尺寸大小。當像素灰度差的平方和的數值越大,表示光斑尺寸越大,反之,則越小。上述的光斑尺寸大小例如以直方圖表示,當直方圖的面積越大,表示像素灰度差的平方和的數值越大,反之,則越小。 In one embodiment, the alignment analysis step calculates the spot size by, for example, the Sum of squared differences (SSD) of the pixel grayscale differences of the respective ultrasonic composite images. The larger the value of the sum of the squares of the pixel gradation differences, the larger the spot size, and vice versa. The above-described spot size is represented, for example, by a histogram. When the area of the histogram is larger, the numerical value indicating the square sum of the pixel gradation differences is larger, and conversely, the smaller is smaller.
接著,在步驟S14中,由此些超音波複合影像中比對出光斑尺寸最小且非相關性數值大於第一設定值的一最適化影像。在步驟S15中,以最適化影像所對應的一發射頻率做為超音波探頭的一最適化參數設定值。 Next, in step S14, an optimized image in which the spot size is the smallest and the non-correlation value is greater than the first set value is compared in the supersonic composite images. In step S15, a transmission frequency corresponding to the optimized image is used as an optimum parameter setting value of the ultrasonic probe.
請參照第3圖,其繪示最適化影像的判斷參考圖。根據上述兩個判斷方法可決定兩條曲線C1、C2,即步驟S11中判斷非相關性所產生的第一曲線C1與步驟S13中判斷光斑尺寸大小所產生的第二曲線C2,其中兩條曲線C1、C2的交叉點AP 用以決定最適化影像所對應的一發射頻率或一發射角度,以做為超音波探頭的一最適化參數設定值SE。 Please refer to FIG. 3, which shows a judgment reference diagram of the optimized image. According to the above two determination methods, two curves C1 and C2 can be determined, that is, the first curve C1 generated by determining the non-correlation in step S11 and the second curve C2 generated by determining the spot size in step S13, wherein the two curves are C1, C2 intersection AP It is used to determine a transmission frequency or a transmission angle corresponding to the optimized image as an optimum parameter setting value SE of the ultrasonic probe.
本發明上述實施例所揭露之超音波探頭的參數設定方法,係針對數位化超音波影像中兩兩影像之間的非相關性進行匹配。將此些數位化超音波影像預合成為多個超音波複合影像,並針此些超音波複合影像進行比對分析,以判斷非相關性數值大於第一設定值的超音波影像的光斑尺寸大小。由此些超音波複合影像中比對出光斑尺寸最小且非相關性數值大於第一設定值的一最適化影像,並以最適化影像所對應的一發射頻率做為超音波探頭的一最適化參數設定值。因此,本發明具有自適應性複合影像超音波調整功能,可針對超音波探頭當下所使用的頻率或角度進行改變或調整,讓每次掃描的時候都可以校正至最佳狀態,以提高超音波成像的品質。 The parameter setting method of the ultrasonic probe disclosed in the above embodiments of the present invention matches the non-correlation between two images in the digitalized ultrasonic image. The digitalized ultrasonic images are pre-synthesized into a plurality of ultrasonic composite images, and the ultrasonic composite images are compared and analyzed to determine the spot size of the ultrasonic image whose non-correlation value is greater than the first set value. . In the supersonic composite image, an optimized image with the smallest spot size and the non-correlation value greater than the first set value is compared, and an emission frequency corresponding to the optimized image is used as an optimization of the ultrasonic probe. Parameter setting value. Therefore, the present invention has an adaptive composite image ultrasonic adjustment function, which can be changed or adjusted for the frequency or angle currently used by the ultrasonic probe, so that each scan can be corrected to an optimal state to improve the ultrasonic wave. The quality of the image.
綜上所述,雖然本發明已以較佳實施例揭露如上,然其並非用以限定本發明。本發明所屬技術領域中具有通常知識者,在不脫離本發明之精神和範圍內,當可作各種之更動與潤飾。因此,本發明之保護範圍當視後附之申請專利範圍所界定者為準。 In conclusion, the present invention has been disclosed in the above preferred embodiments, and is not intended to limit the present invention. A person skilled in the art can make various changes and modifications without departing from the spirit and scope of the invention. Therefore, the scope of the invention is defined by the scope of the appended claims.
S10~S15‧‧‧各個步驟 S10~S15‧‧‧Steps
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