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TWI495450B - Interior organism heating apparatus - Google Patents

Interior organism heating apparatus Download PDF

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Publication number
TWI495450B
TWI495450B TW102118465A TW102118465A TWI495450B TW I495450 B TWI495450 B TW I495450B TW 102118465 A TW102118465 A TW 102118465A TW 102118465 A TW102118465 A TW 102118465A TW I495450 B TWI495450 B TW I495450B
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Taiwan
Prior art keywords
magnetic field
coil
induction coil
generator
ejector
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TW102118465A
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Chinese (zh)
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TW201444526A (en
Inventor
Ching Hua Chiu
Shih Pei Chang
Pei Lain Chen
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Univ Central Taiwan Sci & Tech
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Publication of TWI495450B publication Critical patent/TWI495450B/en

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Description

植入式局部細胞組織加熱裝置Implantable local cell tissue heating device

本發明是一種癌細胞的治療設備,尤其是利用電磁感應產生之熱能之治療設備。The invention is a therapeutic device for cancer cells, in particular a therapeutic device using thermal energy generated by electromagnetic induction.

癌細胞之治療通常為化學治療或放射線治療,其雖可有效殺死癌細胞,但是對於正常細胞也會造成一定程度的傷害。The treatment of cancer cells is usually chemotherapy or radiation therapy, which can effectively kill cancer cells, but it also causes a certain degree of damage to normal cells.

為了改善前述這些問題,標靶藥物、加馬刀等可以將治療手段局限於罹患癌細胞區域,藉以降低對其他正常細胞之傷害。然而,對於前述該些先進的治療方法,其主要的問題在於成本太過於高昂,對於多數的病患,並無力負擔該些種類的治療;而且,該些種類的治療通常需要龐大且昂貴的設備,投資龐大且管理困難也是難以普及的原因。In order to improve these problems, target drugs, plus a knife can be used to limit the treatment to cancer cells, thereby reducing damage to other normal cells. However, for the aforementioned advanced treatment methods, the main problem is that the cost is too high, and for most patients, it is not able to afford these kinds of treatments; moreover, these kinds of treatments usually require large and expensive equipment. The reason for the huge investment and management difficulties is also difficult to popularize.

為了解決既有癌細胞治療方式昂貴、使用不便、投資金額龐大或管理困難之技術問題,進一步造成普及率低的問題,本發明提出一種簡便且電磁感應加熱方式,不僅解決既有技術昂貴等諸多問題,更可以讓病患有機會可以自行在家 治療,達到居家自我照護之可行性。In order to solve the technical problem that the cancer cancer treatment method is expensive, the use is inconvenient, the investment amount is large, or the management is difficult, and the problem of low penetration rate is further caused, the present invention proposes a simple and electromagnetic induction heating method, which not only solves the problem that the existing technology is expensive, and the like. The problem is that the chance of getting sick can be at home. Treatment, to achieve the feasibility of home self-care.

本發明提供一種植入式局部細胞組織加熱裝置,其包含一個以上感應線圈、一線圈植入裝置及一磁場產生器,該線圈植入裝置係將一個以上的該感應線圈植入一生物體之一癌細胞對應位置,該磁場產生器提供一磁場輸出,使置於該生物體內的該感應線圈產生感應電流及熱。The invention provides an implantable partial cell tissue heating device, which comprises more than one induction coil, a coil implant device and a magnetic field generator, wherein the coil implant device implants one or more of the induction coils into one organism The cancer cell corresponds to a position, and the magnetic field generator provides a magnetic field output to cause the induction coil placed in the living body to generate an induced current and heat.

其中,該磁場產生器係先輸出一磁場至該感應線圈,該磁場產生器再感應該感應線圈產生之一感應磁場判斷該感應線圈與該磁場產生器之相對距離關係後,依據相對距離對應產出一強力磁場至該感應線圈。Wherein, the magnetic field generator first outputs a magnetic field to the induction coil, and the magnetic field generator senses an induced magnetic field of the induction coil to determine a relative distance relationship between the induction coil and the magnetic field generator, and then corresponds to the relative distance. A strong magnetic field is applied to the induction coil.

其中,該線圈植入裝置包含一本體、一驅動器、一傳動軸、一轉軸、一旋刀及一線圈頂出組,該本體包含兩個相互平行固定連結設置的筒體,其內形成一傳動軸容置空間、一頂出組容置空間,該傳動軸容置空間內置該傳動軸,該驅動器與該傳動軸之一端固定連接並驅動該傳動軸轉動,該傳動軸之另一端連接該轉軸,該轉軸與該旋刀固定連接,該旋刀之長度方向與該傳軸之軸向垂直或維持一角度關係。The coil implanting device comprises a body, a driver, a drive shaft, a rotating shaft, a rotary cutter and a coil ejector group. The body comprises two cylinders fixedly connected in parallel, and a transmission is formed therein. a shaft accommodating space, a top accommodating space, the drive shaft accommodating space has a built-in drive shaft, the drive is fixedly connected with one end of the drive shaft and drives the drive shaft to rotate, and the other end of the drive shaft is connected to the shaft The rotating shaft is fixedly connected to the rotating cutter, and the longitudinal direction of the rotating cutter is perpendicular to the axial direction of the transmitting shaft or maintains an angular relationship.

其中,該線圈頂出組包含一頂桿、一回復彈性件及一頂出按鍵,該頂桿可活動置於該頂出組容置空間內,該回復彈性件套設於該頂桿外,且該回復彈性件兩端分別與該頂桿與該本體之局部表面連接,該回復彈性件提供該頂桿回復置於該頂出組容置空間之特定位置之施力;該頂出按鍵活動套設於該本體外且與該頂桿之一第一端位置對應,該頂出按鍵相對於該本體運動時,使該頂桿之一第二端突 出於該本體,將置於該本體內的一個該感應線圈推出於該本體外。The coil ejector group includes a ejector pin, a return elastic member and an ejector button. The ejector pin is movable in the ejector group accommodating space, and the responsive elastic member is sleeved outside the ejector pin. And the two ends of the rest elastic member are respectively connected with the ejector rod and a partial surface of the body, and the return elastic member provides a urging force for the ejector rod to return to a specific position of the ejector group accommodating space; the ejector button activity Nested on the outside of the body and corresponding to the first end position of the ram, the ejector button is moved relative to the body, causing the second end of the ram to protrude For the body, one of the induction coils placed in the body is pushed out of the body.

其中,該磁場產生器包含串接之一磁場產生模組、一開關及一電源,該磁場產生組包含一線圈及一磁場共振產生器,該電源提供該磁場產生組產生磁場所需之電力,該磁場共振產生器感應外部之該感應線圈產生之感應磁場判斷該感應線圈之距離,並依據距離判斷結果調整輸出之磁場強度。Wherein, the magnetic field generator comprises a magnetic field generating module connected in series, a switch and a power source, the magnetic field generating group comprising a coil and a magnetic field resonance generator, wherein the power source provides power required by the magnetic field generating group to generate a magnetic field, The magnetic field resonance generator senses the induced magnetic field generated by the external induction coil to determine the distance of the induction coil, and adjusts the output magnetic field strength according to the distance judgment result.

由前述說明可知,本發明具備下列特點:As can be seen from the foregoing description, the present invention has the following features:

1.可以植入複數個感應線圈至癌細胞附近,並透過放在生物體外的磁場產生器驅使該感應線圈產生高熱而殺死癌細胞,整體構造簡單。1. Multiple induction coils can be implanted near the cancer cells, and the magnetic field generator placed outside the body drives the induction coil to generate high heat to kill the cancer cells, and the overall structure is simple.

2.磁場產生器之體積遠小於產生放射性射線之設備,因此,本發明可以實現居家自我照護之技術效果。2. The volume of the magnetic field generator is much smaller than that of the device that generates radioactive rays. Therefore, the present invention can achieve the technical effect of home self-care.

10‧‧‧感應線圈10‧‧‧Induction coil

20‧‧‧線圈植入裝置20‧‧‧Coil implant device

21‧‧‧本體21‧‧‧ body

211‧‧‧傳動軸容置空間211‧‧‧Drive shaft accommodation space

212‧‧‧頂出組容置空間212‧‧‧Out of the group accommodation space

213‧‧‧限位塊213‧‧‧Limited blocks

22‧‧‧驅動器22‧‧‧ Drive

24‧‧‧傳動軸24‧‧‧ drive shaft

26‧‧‧轉軸26‧‧‧ shaft

28‧‧‧旋刀28‧‧‧Rottor

29‧‧‧線圈頂出組29‧‧‧Coil ejection group

291‧‧‧頂桿291‧‧‧Pole

292‧‧‧回復彈性件292‧‧‧Respond to elastic parts

293‧‧‧頂出按鍵293‧‧‧Top button

30‧‧‧磁場產生器30‧‧‧Magnetic field generator

32‧‧‧磁場產生組32‧‧‧Magnetic field generating group

322‧‧‧線圈322‧‧‧ coil

321‧‧‧磁場共振產生器321‧‧‧Magnetic resonance generator

34‧‧‧電源34‧‧‧Power supply

341‧‧‧開關341‧‧‧ switch

50‧‧‧生物體50‧‧‧ organisms

52‧‧‧癌細胞52‧‧‧ cancer cells

第一圖為本發明較佳實施例之磁場產生器之使用示意圖。The first figure is a schematic view of the use of a magnetic field generator in accordance with a preferred embodiment of the present invention.

第一A圖為本發明較佳實施例之磁場產生器之電路方塊示意圖。Figure 1A is a block diagram showing the circuit of a magnetic field generator in accordance with a preferred embodiment of the present invention.

第二圖為本發明較佳實施例之線圈植入裝置使用示意圖The second figure is a schematic diagram of the use of the coil implanting device of the preferred embodiment of the present invention.

第三圖為本發明較佳實施例之線圈植入裝置使用示意圖。The third figure is a schematic view of the use of the coil implanting device of the preferred embodiment of the present invention.

第四圖為本發明較佳實施例之線圈植入裝置使用示意 圖。The fourth figure is a schematic view of the use of the coil implanting device of the preferred embodiment of the present invention. Figure.

第五圖為本發明較佳實施例之植入感應線圈之流程示意圖。The fifth figure is a schematic flow chart of implanting an induction coil according to a preferred embodiment of the present invention.

第六圖為本發明較佳實施例之產生感應磁場之流程示意圖。Figure 6 is a flow diagram showing the process of generating an induced magnetic field in accordance with a preferred embodiment of the present invention.

請參考第一圖、第一A圖、第二圖、第三圖及第四圖,其為本發明植入式局部細胞組織加熱裝置較佳實施例,其包含一個以上感應線圈10、一線圈植入裝置20及一磁場產生器30。該線圈植入裝置20可將一個以上的該感應線圈10植入一生物體50之一癌細胞52對應位置,該磁場產生器30提供一磁場輸出,使置於該生物體50內的該感應線圈10產生感應電流,使該感應線圈10產生熱,所產生的熱可以燒除或降低該癌細胞52之存活率。該感應線圈10為一封閉迴路,其感應磁場後,於該感應線圈10產生感應電流而加熱。Please refer to the first figure, the first A figure, the second figure, the third figure and the fourth figure, which is a preferred embodiment of the implantable partial cell tissue heating device of the present invention, which comprises more than one induction coil 10 and a coil. The device 20 is implanted and a magnetic field generator 30. The coil implanting device 20 can implant more than one of the induction coils 10 into a corresponding position of a cancer cell 52 of a living body 50. The magnetic field generator 30 provides a magnetic field output for the induction coil placed in the living body 50. 10 generates an induced current that causes the induction coil 10 to generate heat, and the generated heat can burn off or reduce the survival rate of the cancer cells 52. The induction coil 10 is a closed circuit. After the magnetic field is induced, an induction current is generated in the induction coil 10 to be heated.

該線圈植入裝置20包含一本體21、一驅動器22、一傳動軸24、一轉軸26、一旋刀28及一線圈頂出組29。該本體21包含兩個相互平行固定連結設置的筒體,其內包含一傳動軸容置空間211、一頂出組容置空間212及一限位塊213,該傳動軸容置空間211與該頂出組容置空間212相鄰設置,該傳動軸容置空間211內置該傳動軸24,該驅動器22與該傳動軸24之一端固定連接並驅動該傳動軸24轉動,該傳動軸24之另一端連接該轉軸26,該轉軸26與該 旋刀28固定連接,該旋刀28之長度方向與該傳動軸24之軸向垂直或維持一角度關係。該限位塊213凸設於該本體21之一外表面。使用時,該驅動器22驅使傳動軸轉動,該旋刀28由該轉軸26驅動對該本體21轉動,該旋刀28係用於切開該生物體50內之組織。The coil implanting device 20 includes a body 21, a driver 22, a drive shaft 24, a rotating shaft 26, a rotary cutter 28 and a coil ejecting group 29. The body 21 includes two cylinders that are fixedly coupled to each other in parallel, and includes a transmission shaft accommodating space 211, a ejector group accommodating space 212, and a limiting block 213. The transmission shaft accommodating space 211 and the The ejector group accommodating space 212 is adjacently disposed. The transmission shaft accommodating space 211 defines the transmission shaft 24, and the driver 22 is fixedly coupled to one end of the transmission shaft 24 and drives the transmission shaft 24 to rotate. One end is connected to the rotating shaft 26, and the rotating shaft 26 is The rotary cutter 28 is fixedly coupled, and the length direction of the rotary cutter 28 is perpendicular to or maintains an angular relationship with the axial direction of the drive shaft 24. The limiting block 213 protrudes from an outer surface of the body 21 . In use, the drive 22 drives the drive shaft to rotate, and the rotary cutter 28 is driven by the rotary shaft 26 to rotate the body 21 for cutting tissue within the living body 50.

該線圈頂出組29包含一頂桿291、一回復彈性件292及一頂出按鍵293,該頂桿291可活動置於該頂出組容置空間內212,該回復彈性件292套設於該頂桿291外,且該回復彈性件292兩端分別與該頂桿291與該本體21之局部表面連接,該回復彈性件292提供該頂桿291回復置於該頂出組容置空間212之特定位置之施力。該頂出按鍵293活動套設於該本體21外且與該頂桿291之一第一端位置對應,該頂出按鍵293相對於該本體21相對運動時,使該頂桿291之一第二端突出於該本體21,並將原先置於該本體21內的該感應線圈10推出於該本體21外。The coil ejector group 29 includes a ejector rod 291, a return elastic member 292 and an ejector button 293. The ejector rod 291 is movably disposed in the ejector group accommodating space 212. The ejector rod 291 is externally connected to the ejector rod 291 and the partial surface of the body 21, and the ejector elastic member 292 is provided to return to the ejector group accommodating space 212. The force of the specific position. The ejection button 293 is sleeved outside the body 21 and corresponds to a first end position of the jack 291. When the ejection button 293 moves relative to the body 21, the second rod 291 is second. The end protrudes from the body 21, and the induction coil 10 originally placed in the body 21 is pushed out of the body 21.

該磁場產生器30包含串接之一磁場產生模組32、一開關341及一電源34,該磁場產生組32包含一線圈322及一磁場共振產生器321,該電源34提供該磁場產生組32產生磁場所需之電力。該磁場共振產生器321係於該開關341開啟後,以該電源34之電力感應該感應線圈10與該線圈322之距離,並驅使該線圈322產生一強力磁場輸出置該感應線圈10。前述該磁場共振產生器321係驅使該線圈322產生相對較弱的磁場朝該感應線圈10之方向輸出,該感應線圈10產生感應電流後所產生的感應磁場反饋輸出至該磁場共振產生器321,該磁場共振產生器321依據由該感應線 圈10接收之感應磁場強度判斷該感應線圈10與該磁場共振產生器321之間距離判斷之效果。當完成距離之判斷後,該磁場共振產生器321驅使該線圈322輸出適當強度的磁場至該感應線圈10,使該感應線圈10產生電流並生熱,如第六圖所示。The magnetic field generator 30 includes a magnetic field generating module 32 connected in series, a switch 341 and a power source 34. The magnetic field generating group 32 includes a coil 322 and a magnetic field resonance generator 321, and the power source 34 provides the magnetic field generating group 32. The power required to generate a magnetic field. The magnetic field resonance generator 321 is configured to sense the distance between the induction coil 10 and the coil 322 by the power of the power source 34, and drive the coil 322 to generate a strong magnetic field to output the induction coil 10. The magnetic field resonance generator 321 drives the coil 322 to generate a relatively weak magnetic field to output the direction of the induction coil 10, and the induction magnetic field generated by the induction coil 10 generates an induced current feedback output to the magnetic field resonance generator 321 . The magnetic field resonance generator 321 is based on the sensing line The intensity of the induced magnetic field received by the circle 10 determines the effect of determining the distance between the induction coil 10 and the magnetic field resonance generator 321. When the determination of the distance is completed, the magnetic field resonance generator 321 drives the coil 322 to output a magnetic field of a suitable intensity to the induction coil 10, causing the induction coil 10 to generate a current and generate heat, as shown in the sixth figure.

使用時,請參考第五圖,以該本體21之自由端穿入該生物體50後,並驅使該旋刀28轉動,於該生物體50內切割一線圈容置空間後,再將該感應線圈10置於該線圈容置空間內。完成後,該旋刀28轉至該本體21之對應位置後將該本體21抽離該生物體。由於該線圈容置空間與該癌細胞52相鄰,故該感應線圈10因感應電流產生的高熱可殺死鄰近癌細胞52或抑制癌細胞52之生長。When in use, please refer to the fifth figure, after the free end of the body 21 penetrates the living body 50, and drives the rotary knife 28 to rotate, after cutting a coil accommodating space in the living body 50, and then inducing the induction The coil 10 is placed in the coil accommodation space. Upon completion, the knife 28 is rotated to the corresponding position of the body 21 and the body 21 is pulled away from the living body. Since the coil accommodation space is adjacent to the cancer cells 52, the induction coil 10 can kill adjacent cancer cells 52 or inhibit the growth of cancer cells 52 due to the high heat generated by the induced current.

由前述說明可知,本發明具備下列特點:As can be seen from the foregoing description, the present invention has the following features:

1.可以植入複數個感應線圈至癌細胞附近,並透過放在生物體外的磁場產生器驅使該感應線圈產生高熱而殺死癌細胞,整體構造簡單。1. Multiple induction coils can be implanted near the cancer cells, and the magnetic field generator placed outside the body drives the induction coil to generate high heat to kill the cancer cells, and the overall structure is simple.

2.磁場產生器之體積遠小於產生放射性射線之設備,因此,本發明可以實現居家自我照護之技術效果。2. The volume of the magnetic field generator is much smaller than that of the device that generates radioactive rays. Therefore, the present invention can achieve the technical effect of home self-care.

10‧‧‧感應線圈10‧‧‧Induction coil

30‧‧‧磁場產生器30‧‧‧Magnetic field generator

32‧‧‧磁場產生組32‧‧‧Magnetic field generating group

322‧‧‧線圈322‧‧‧ coil

34‧‧‧電源34‧‧‧Power supply

50‧‧‧生物體50‧‧‧ organisms

52‧‧‧癌細胞52‧‧‧ cancer cells

Claims (6)

一種植入式局部細胞組織加熱裝置,其包含一個以上感應線圈、一線圈植入裝置及一磁場產生器,該線圈植入裝置係將一個以上的該感應線圈植入一生物體之一癌細胞對應位置,該磁場產生器提供一磁場輸出,使置於該生物體內的該感應線圈產生感應電流及熱,其中:該磁場產生器係先輸出一磁場至該感應線圈,該磁場產生器再感應該感應線圈產生之一感應磁場判斷該感應線圈與該磁場產生器之相對距離關係後,依據相對距離對應產出一強力磁場至該感應線圈;及該線圈植入裝置包含一本體、一驅動器、一傳動軸、一轉軸、一旋刀及一線圈頂出組,該本體包含兩個相互平行固定連結設置的筒體,其內形成一傳動軸容置空間、一頂出組容置空間,該傳動軸容置空間內置該傳動軸,該驅動器與該傳動軸之一端固定連接並驅動該傳動軸轉動,該傳動軸之另一端連接該轉軸,該轉軸與該旋刀固定連接,該旋刀之長度方向與該傳軸之軸向垂直或維持一角度關係。 An implantable partial cell tissue heating device comprising more than one induction coil, a coil implantation device and a magnetic field generator, wherein the coil implantation device implants one or more of the induction coils into a cancer cell corresponding to one of the organisms Position, the magnetic field generator provides a magnetic field output, the induction coil placed in the living body generates an induced current and heat, wherein: the magnetic field generator first outputs a magnetic field to the induction coil, and the magnetic field generator senses the The induction coil generates an induced magnetic field to determine a relative distance relationship between the induction coil and the magnetic field generator, and correspondingly generates a strong magnetic field according to the relative distance to the induction coil; and the coil implanting device comprises a body, a driver, and a a driving shaft, a rotating shaft, a rotating knife and a coil ejector group, the body comprises two cylindrical bodies fixedly connected in parallel, and a driving shaft accommodating space and a ejector group accommodating space are formed therein, the transmission The shaft accommodating space has a built-in drive shaft, and the drive is fixedly connected with one end of the drive shaft and drives the drive shaft to rotate, the drive shaft Connected to the end of a rotating shaft fixedly connected with the rotary blade, the longitudinal direction of the knife at an angle perpendicular to the axial relationship of the transmission axis or maintained. 如申請專利範圍第1項所述的植入式局部細胞組織加熱裝置,該線圈頂出組包含一頂桿、一回復彈性件及一頂出按鍵,該頂桿可活動置於該頂出組容置空間內,該回復彈性件套設於該頂桿外,且該回復彈性件兩端分別與該頂桿與該本體之局部表面連接,該回復彈性件提供該頂桿回復置於該頂出組容置空間之特定位置之施力;該頂出按鍵活動套設於該本體外且與該頂桿之一第一端位置對應, 該頂出按鍵相對於該本體運動時,使該頂桿之一第二端突出於該本體,將置於該本體內的一個該感應線圈推出於該本體外。 The implantable partial cell tissue heating device according to claim 1, wherein the coil ejection group comprises a plunger, a return elastic member and an ejection button, and the plunger is movable in the ejection group. In the accommodating space, the rest elastic member is sleeved outside the ejector pin, and the two ends of the repulsion elastic member are respectively connected with the ejector bar and a partial surface of the body, and the return elastic member provides the ejector lever to be placed on the top Applying a force to a specific position of the accommodating space; the ejector button is sleeved outside the body and corresponds to a first end position of the ejector pin, When the ejector button is moved relative to the body, the second end of the ejector pin protrudes from the body, and one of the induction coils placed in the body is pushed out of the body. 如申請專利範圍第2項所述的植入式局部細胞組織加熱裝置,該磁場產生器包含串接之一磁場產生模組、一開關及一電源,該磁場產生組包含一線圈及一磁場共振產生器,該電源提供該磁場產生組產生磁場所需之電力,該磁場共振產生器感應外部之該感應線圈產生之感應磁場判斷該感應線圈之距離,並依據距離判斷結果調整輸出之磁場強度。 The implantable local cell tissue heating device according to claim 2, wherein the magnetic field generator comprises a magnetic field generating module connected in series, a switch and a power source, the magnetic field generating group comprising a coil and a magnetic field resonance a generator that supplies the power required by the magnetic field generating group to generate a magnetic field, the magnetic field resonance generator sensing an external induced magnetic field of the induction coil to determine the distance of the induction coil, and adjusting the output magnetic field strength according to the distance judgment result. 如申請專利範圍第3項所述的植入式局部細胞組織加熱裝置,該感應線圈為封閉迴路。 The implantable partial cell tissue heating device of claim 3, wherein the induction coil is a closed loop. 如申請專利範圍第1項所述的植入式局部細胞組織加熱裝置,該磁場產生器包含串接之一磁場產生模組、一開關及一電源,該磁場產生組包含一線圈及一磁場共振產生器,該電源提供該磁場產生組產生磁場所需之電力,該磁場共振產生器感應外部之該感應線圈產生之感應磁場判斷該感應線圈之距離,並依據距離判斷結果調整輸出之磁場強度。 The implantable local cell tissue heating device according to claim 1, wherein the magnetic field generator comprises a magnetic field generating module connected in series, a switch and a power source, the magnetic field generating group comprising a coil and a magnetic field resonance a generator that supplies the power required by the magnetic field generating group to generate a magnetic field, the magnetic field resonance generator sensing an external induced magnetic field of the induction coil to determine the distance of the induction coil, and adjusting the output magnetic field strength according to the distance judgment result. 如申請專利範圍第5項所述的植入式局部細胞組織加熱裝置,該感應線圈為封閉迴路。The implantable partial cell tissue heating device of claim 5, wherein the induction coil is a closed loop.
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