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TWI368512B - Pharmaceutical compositions comprising chlorophenyl piperazine derived compounds and use of the compounds in producing medicaments - Google Patents

Pharmaceutical compositions comprising chlorophenyl piperazine derived compounds and use of the compounds in producing medicaments

Info

Publication number
TWI368512B
TWI368512B TW098114472A TW98114472A TWI368512B TW I368512 B TWI368512 B TW I368512B TW 098114472 A TW098114472 A TW 098114472A TW 98114472 A TW98114472 A TW 98114472A TW I368512 B TWI368512 B TW I368512B
Authority
TW
Taiwan
Prior art keywords
compounds
pharmaceutical compositions
producing medicaments
chlorophenyl piperazine
piperazine derived
Prior art date
Application number
TW098114472A
Other languages
English (en)
Other versions
TW201038274A (en
Inventor
Ing Jun Chen
Original Assignee
Univ Kaohsiung Medical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kaohsiung Medical filed Critical Univ Kaohsiung Medical
Priority to TW098114472A priority Critical patent/TWI368512B/zh
Priority to US12/620,448 priority patent/US20100280039A1/en
Publication of TW201038274A publication Critical patent/TW201038274A/zh
Priority to US13/340,041 priority patent/US20120094985A1/en
Application granted granted Critical
Publication of TWI368512B publication Critical patent/TWI368512B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW098114472A 2009-04-30 2009-04-30 Pharmaceutical compositions comprising chlorophenyl piperazine derived compounds and use of the compounds in producing medicaments TWI368512B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
TW098114472A TWI368512B (en) 2009-04-30 2009-04-30 Pharmaceutical compositions comprising chlorophenyl piperazine derived compounds and use of the compounds in producing medicaments
US12/620,448 US20100280039A1 (en) 2009-04-30 2009-11-17 Pharmaceutical compositions comprising chlorophenyl piperazine derived compounds and use of the compounds in producing medicaments
US13/340,041 US20120094985A1 (en) 2009-04-30 2011-12-29 Pharmaceutical compositions comprising chlorophenyl piperazine derived compounds and use of the compounds in producing medicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TW098114472A TWI368512B (en) 2009-04-30 2009-04-30 Pharmaceutical compositions comprising chlorophenyl piperazine derived compounds and use of the compounds in producing medicaments

Publications (2)

Publication Number Publication Date
TW201038274A TW201038274A (en) 2010-11-01
TWI368512B true TWI368512B (en) 2012-07-21

Family

ID=43030854

Family Applications (1)

Application Number Title Priority Date Filing Date
TW098114472A TWI368512B (en) 2009-04-30 2009-04-30 Pharmaceutical compositions comprising chlorophenyl piperazine derived compounds and use of the compounds in producing medicaments

Country Status (2)

Country Link
US (2) US20100280039A1 (zh)
TW (1) TWI368512B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI368511B (en) * 2009-04-30 2012-07-21 Univ Kaohsiung Medical Synthesis and pharmacokinetic activities of pulmodil and pulmodil-1, two chlorophenylpiperazine salt derivatives
US8470805B2 (en) * 2009-04-30 2013-06-25 Kaohsiung Medical University Processes for preparing piperazinium salts of KMUP and use thereof
US9819471B2 (en) 2013-11-04 2017-11-14 Texas Instruments Incorporated Method and apparatus for configuration, measurement and reporting of channel state information for LTE TDD with dynamic UL/DL configuration

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants
US6979687B1 (en) * 2002-09-27 2005-12-27 Ing-Jun Chen Theophylline-based soluble guanylyl cyclase activators KMUP-1 analogues enhanced cyclic GMP and K+ channel activities on rabbit corpus cavernosum smooth muscle and intercavernous pressure activities

Also Published As

Publication number Publication date
US20100280039A1 (en) 2010-11-04
US20120094985A1 (en) 2012-04-19
TW201038274A (en) 2010-11-01

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