TWI367879B - N-(heteroaryl)-1h-indole-2-carboxamide derivatives, preparation thereof and therapeutic application thereof - Google Patents

N-(heteroaryl)-1h-indole-2-carboxamide derivatives, preparation thereof and therapeutic application thereof

Info

Publication number: TWI367879B
Authority: TW; Taiwan
Prior art keywords: indole; heteroaryl; preparation; therapeutic application; carboxamide derivatives
Prior art date: 2005-01-07

Application number

TW095100688A

Other languages

English (en)

Chinese (zh)

Other versions

TW200635896A (en

Inventor

Laurent Dubois

Yannick Evanno

Andre Malanda

Original Assignee

Sanofi Aventis

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-01-07

Filing date

2006-01-06

Publication date

2012-07-11

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34955041&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TWI367879(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-01-06 Application filed by Sanofi Aventis filed Critical Sanofi Aventis

2006-10-16 Publication of TW200635896A publication Critical patent/TW200635896A/zh

2012-07-11 Application granted granted Critical

2012-07-11 Publication of TWI367879B publication Critical patent/TWI367879B/zh

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Virology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Dermatology (AREA)
Biotechnology (AREA)
Rheumatology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Ophthalmology & Optometry (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

TW095100688A 2005-01-07 2006-01-06 N-(heteroaryl)-1h-indole-2-carboxamide derivatives, preparation thereof and therapeutic application thereof TWI367879B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0550068A FR2880625B1 (fr)	2005-01-07	2005-01-07	Derives de n-(heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique

Publications (2)

Publication Number	Publication Date
TW200635896A TW200635896A (en)	2006-10-16
TWI367879B true TWI367879B (en)	2012-07-11

Family

ID=34955041

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW095100688A TWI367879B (en)	2005-01-07	2006-01-06	N-(heteroaryl)-1h-indole-2-carboxamide derivatives, preparation thereof and therapeutic application thereof

Country Status (35)

Country	Link
US (2)	US7407950B2 (es)
EP (1)	EP1841737B1 (es)
JP (1)	JP5242167B2 (es)
KR (1)	KR101288698B1 (es)
CN (1)	CN101115718B (es)
AR (1)	AR052450A1 (es)
AT (1)	ATE460397T1 (es)
AU (1)	AU2006204405B2 (es)
BR (1)	BRPI0606472A2 (es)
CA (1)	CA2594418C (es)
CR (1)	CR9210A (es)
CY (1)	CY1110647T1 (es)
DE (1)	DE602006012802D1 (es)
DK (1)	DK1841737T3 (es)
EA (1)	EA013264B1 (es)
ES (1)	ES2342318T3 (es)
FR (1)	FR2880625B1 (es)
HR (1)	HRP20100297T1 (es)
IL (1)	IL184268A (es)
MA (1)	MA29239B1 (es)
MX (1)	MX2007008308A (es)
MY (1)	MY145932A (es)
NO (1)	NO20073811L (es)
NZ (1)	NZ556318A (es)
PE (1)	PE20061019A1 (es)
PL (1)	PL1841737T3 (es)
PT (1)	PT1841737E (es)
RS (1)	RS51358B (es)
SI (1)	SI1841737T1 (es)
TN (1)	TNSN07253A1 (es)
TW (1)	TWI367879B (es)
UA (1)	UA93668C2 (es)
UY (1)	UY29327A1 (es)
WO (1)	WO2006072736A1 (es)
ZA (1)	ZA200705548B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
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FR2874015B1 (fr) *	2004-08-05	2006-09-15	Sanofi Synthelabo	Derives de n-(1h-indolyl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
FR2888847B1 (fr)	2005-07-22	2007-08-31	Sanofi Aventis Sa	Derives de n-(heteriaryl)-1-heteorarylalkyl-1h-indole-2- carboxamides, leur preparation et application en therapeutique
FR2903985B1 (fr)	2006-07-24	2008-09-05	Sanofi Aventis Sa	Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
FR2904316B1 (fr) *	2006-07-31	2008-09-05	Sanofi Aventis Sa	Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique.
MX2009006473A (es) *	2006-12-15	2009-08-25	Janssen Pharmaceutica Nv	Inhibidores de receptor vainilloide de bencimidazol.
FR2911604B1 (fr)	2007-01-19	2009-04-17	Sanofi Aventis Sa	Derives de n-(heteroaryl-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
KR20100066422A (ko) *	2007-08-10	2010-06-17	하. 룬트벡 아크티에 셀스카브	헤테로아릴 아미드 유사체
EP2240467B1 (en) *	2008-01-09	2013-03-20	Evotec AG	Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
FR2926555B1 (fr)	2008-01-22	2010-02-19	Sanofi Aventis	Derives bicycliques de carboxamides azabicycliques, leur preparation et leur application en therapeutique
FR2926556B1 (fr) *	2008-01-22	2010-02-19	Sanofi Aventis	Derives de carboxamides n-azabicycliques, leur preparation et leur application en therapeutique
FR2926554B1 (fr)	2008-01-22	2010-03-12	Sanofi Aventis	Derives de carboxamides azabicycliques, leur preparation et leur application en therapeutique
PL2629610T3 (pl)	2010-07-27	2018-02-28	Flex Pharma, Inc.	Sposoby i kompozycje do zapobiegania i zmniejszania kurczy mięśni i do regeneracji po nerwowo-mięśniowym podrażnieniu i zmęczeniu po ćwiczeniach fizycznych
KR101293384B1 (ko) *	2010-10-13	2013-08-05	주식회사 대웅제약	신규 피리딜 벤조옥사진 유도체, 이를 포함하는 약학 조성물 및 이의 용도
US11253493B2 (en)	2017-01-23	2022-02-22	Cliff-Cartwright Corporation	Compositions and methods affecting exercise performance
CN120398870A (zh) *	2024-01-31	2025-08-01	深圳晶蛋生物医药科技有限公司	一种苯并吗啉类化合物及其应用

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KR100508200B1 (ko) *	1996-02-13	2005-12-16	아보트 러보러터리즈	엔도텔린길항제로서의벤조-1,3-디옥솔릴-및벤조푸라닐치환된피롤리딘유도체및이를함유하는약제
ATE206701T1 (de) *	1996-04-19	2001-10-15	American Home Prod	Östrogene verbindungen
TR200101233T2 (tr) *	1997-08-04	2002-06-21	Abbott Laboratories	Endotelin antagonistleri.
UA68365C2 (en) *	1997-11-06	2004-08-16	Wyeth Corp	Peroral contraception by combination of anti-estrogen and progestin
HU227568B1 (en) *	1997-12-24	2011-08-29	Sanofi Aventis Deutschland	Indole derivatives, as inhibitors os factor xa
JP2002515431A (ja) *	1998-05-15	2002-05-28	アメリカン・ホーム・プロダクツ・コーポレイション	エストロゲンと組み合わせる２−フェニル−１−［４−（２−アミノエトキシ）ベンジルオキシ］インドール
CO5180550A1 (es) *	1999-04-19	2002-07-30	Smithkline Beecham Corp	Inhibidores de fab i
AR030064A1 (es) *	2000-07-06	2003-08-13	Wyeth Corp	Metodos para inhibir los efectos uterotroficos de los agentes estrogenicos
EP1314733A1 (en) *	2001-11-22	2003-05-28	Aventis Pharma Deutschland GmbH	Indole-2-carboxamides as factor Xa inhibitors
ES2316777T3 (es) *	2002-02-15	2009-04-16	Glaxo Group Limited	Moduladores de receptores vainilloides.
EP1578418A2 (en) *	2002-12-20	2005-09-28	Bayer HealthCare AG	Use of substituted 2,5-diamidoindoles for the treatment of urological diseases
ES2337254T3 (es) *	2003-02-14	2010-04-22	Glaxo Group Limited	Derivados de carboxamida.
AR045979A1 (es) *	2003-04-28	2005-11-23	Astrazeneca Ab	Amidas heterociclicas
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FR2874015B1 (fr) *	2004-08-05	2006-09-15	Sanofi Synthelabo	Derives de n-(1h-indolyl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique

2005
- 2005-01-07 FR FR0550068A patent/FR2880625B1/fr not_active Expired - Fee Related
2006
- 2006-01-04 BR BRPI0606472-8A patent/BRPI0606472A2/pt not_active Application Discontinuation
- 2006-01-04 RS RSP-2010/0259A patent/RS51358B/sr unknown
- 2006-01-04 WO PCT/FR2006/000008 patent/WO2006072736A1/fr not_active Ceased
- 2006-01-04 CA CA2594418A patent/CA2594418C/fr not_active Expired - Fee Related
- 2006-01-04 EA EA200701451A patent/EA013264B1/ru not_active IP Right Cessation
- 2006-01-04 ZA ZA200705548A patent/ZA200705548B/xx unknown
- 2006-01-04 DK DK06704665.6T patent/DK1841737T3/da active
- 2006-01-04 ES ES06704665T patent/ES2342318T3/es not_active Expired - Lifetime
- 2006-01-04 CN CN2006800042385A patent/CN101115718B/zh not_active Expired - Fee Related
- 2006-01-04 AU AU2006204405A patent/AU2006204405B2/en not_active Ceased
- 2006-01-04 AT AT06704665T patent/ATE460397T1/de active
- 2006-01-04 MX MX2007008308A patent/MX2007008308A/es active IP Right Grant
- 2006-01-04 DE DE602006012802T patent/DE602006012802D1/de not_active Expired - Lifetime
- 2006-01-04 KR KR1020077018041A patent/KR101288698B1/ko not_active Expired - Fee Related
- 2006-01-04 NZ NZ556318A patent/NZ556318A/en not_active IP Right Cessation
- 2006-01-04 JP JP2007549933A patent/JP5242167B2/ja not_active Expired - Fee Related
- 2006-01-04 PL PL06704665T patent/PL1841737T3/pl unknown
- 2006-01-04 AR ARP060100023A patent/AR052450A1/es unknown
- 2006-01-04 HR HR20100297T patent/HRP20100297T1/hr unknown
- 2006-01-04 PE PE2006000037A patent/PE20061019A1/es not_active Application Discontinuation
- 2006-01-04 EP EP06704665A patent/EP1841737B1/fr not_active Expired - Lifetime
- 2006-01-04 SI SI200630674T patent/SI1841737T1/sl unknown
- 2006-01-04 PT PT06704665T patent/PT1841737E/pt unknown
- 2006-01-04 MY MYPI20060030A patent/MY145932A/en unknown
- 2006-01-05 UY UY29327A patent/UY29327A1/es not_active Application Discontinuation
- 2006-01-06 TW TW095100688A patent/TWI367879B/zh not_active IP Right Cessation
- 2006-04-01 UA UAA200709046A patent/UA93668C2/ru unknown
2007
- 2007-06-20 US US11/765,687 patent/US7407950B2/en not_active Expired - Fee Related
- 2007-06-26 CR CR9210A patent/CR9210A/es unknown
- 2007-06-27 IL IL184268A patent/IL184268A/en not_active IP Right Cessation
- 2007-07-03 TN TNP2007000253A patent/TNSN07253A1/fr unknown
- 2007-07-20 NO NO20073811A patent/NO20073811L/no not_active Application Discontinuation
- 2007-07-26 MA MA30112A patent/MA29239B1/fr unknown
2008
- 2008-06-20 US US12/143,066 patent/US7557134B2/en not_active Expired - Fee Related
2010
- 2010-06-01 CY CY20101100482T patent/CY1110647T1/el unknown

Also Published As

Publication number	Publication date
MY145932A (en)	2012-05-31
PT1841737E (pt)	2010-06-11
US20080255131A1 (en)	2008-10-16
AR052450A1 (es)	2007-03-21
WO2006072736A1 (fr)	2006-07-13
MX2007008308A (es)	2007-09-07
RS51358B (sr)	2011-02-28
CR9210A (es)	2008-01-21
US20070259946A1 (en)	2007-11-08
PE20061019A1 (es)	2006-10-30
FR2880625A1 (fr)	2006-07-14
BRPI0606472A2 (pt)	2009-06-30
IL184268A (en)	2011-10-31
US7557134B2 (en)	2009-07-07
TW200635896A (en)	2006-10-16
EP1841737B1 (fr)	2010-03-10
PL1841737T3 (pl)	2010-08-31
AU2006204405B2 (en)	2012-05-10
UY29327A1 (es)	2006-08-31
EP1841737A1 (fr)	2007-10-10
ZA200705548B (en)	2008-10-29
CY1110647T1 (el)	2015-06-10
AU2006204405A1 (en)	2006-07-13
DK1841737T3 (da)	2010-07-05
US7407950B2 (en)	2008-08-05
HRP20100297T1 (hr)	2010-07-31
CA2594418C (fr)	2014-03-25
IL184268A0 (en)	2007-10-31
TNSN07253A1 (fr)	2008-12-31
JP5242167B2 (ja)	2013-07-24
NZ556318A (en)	2011-02-25
EA200701451A1 (ru)	2008-02-28
HK1117506A1 (en)	2009-01-16
JP2008526820A (ja)	2008-07-24
KR20070094833A (ko)	2007-09-21
NO20073811L (no)	2007-09-27
MA29239B1 (fr)	2008-02-01
UA93668C2 (en)	2011-03-10
ES2342318T3 (es)	2010-07-05
CN101115718A (zh)	2008-01-30
FR2880625B1 (fr)	2007-03-09
ATE460397T1 (de)	2010-03-15
DE602006012802D1 (de)	2010-04-22
KR101288698B1 (ko)	2013-07-22
SI1841737T1 (sl)	2010-07-30
EA013264B1 (ru)	2010-04-30
CN101115718B (zh)	2011-06-08
CA2594418A1 (fr)	2006-07-13

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