TW202438056A - 雜環化合物及其用途 - Google Patents

雜環化合物及其用途 Download PDF

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Publication number: TW202438056A
Authority: TW; Taiwan
Prior art keywords: cycloalkyl; heterocycloalkyl; alkyl; aryl; heteroaryl
Prior art date: 2023-03-22

Application number

TW112142031A

Other languages

English (en)

Chinese (zh)

Inventor

小明李

劉源

平達任

連生李

Original Assignee

美商金橘生物科技公司

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2023-03-22

Filing date

2023-11-01

Publication date

2024-10-01

2023-05-03 Priority claimed from PCT/US2023/066569 external-priority patent/WO2023215801A1/en

2023-11-01 Application filed by 美商金橘生物科技公司 filed Critical 美商金橘生物科技公司

2024-10-01 Publication of TW202438056A publication Critical patent/TW202438056A/zh

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150000002391 heterocyclic compounds Chemical class 0.000 title 1
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150000003839 salts Chemical class 0.000 claims abstract description 75
238000000034 method Methods 0.000 claims abstract description 19
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229910020008 S(O) Inorganic materials 0.000 claims description 759
125000000217 alkyl group Chemical group 0.000 claims description 466
125000000592 heterocycloalkyl group Chemical group 0.000 claims description 445
125000001072 heteroaryl group Chemical group 0.000 claims description 419
125000003118 aryl group Chemical group 0.000 claims description 415
125000000882 C2-C6 alkenyl group Chemical group 0.000 claims description 313
125000003601 C2-C6 alkynyl group Chemical group 0.000 claims description 313
125000006376 (C3-C10) cycloalkyl group Chemical group 0.000 claims description 292
229910052799 carbon Inorganic materials 0.000 claims description 204
229910052739 hydrogen Inorganic materials 0.000 claims description 158
239000001257 hydrogen Substances 0.000 claims description 134
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150000002431 hydrogen Chemical class 0.000 claims description 102
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239000012453 solvate Substances 0.000 claims description 74
229910052757 nitrogen Inorganic materials 0.000 claims description 73
239000003112 inhibitor Substances 0.000 claims description 68
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Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

TW112142031A 2023-03-22 2023-11-01 雜環化合物及其用途 TW202438056A (zh)

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PCT/US2023/066569 WO2023215801A1 (en)	2022-05-04	2023-05-03	Heterocyclic compounds and uses thereof

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