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TW202011900A - 栓塞編織物的遞送系統 - Google Patents

栓塞編織物的遞送系統 Download PDF

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TW202011900A
TW202011900A TW108127999A TW108127999A TW202011900A TW 202011900 A TW202011900 A TW 202011900A TW 108127999 A TW108127999 A TW 108127999A TW 108127999 A TW108127999 A TW 108127999A TW 202011900 A TW202011900 A TW 202011900A
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萊希 戈羅喬
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美商德派信迪思產品公司
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Abstract

一種藉由在治療部位處從一遞送系統釋放一植入的植入物來治療動脈瘤的裝置，該裝置可包括附接至一釋放部件的一編織植入物，該釋放部件可與一遞送管及一拉線可拆卸地接合。該釋放部件可經由摩擦配合以一壓縮構形接合該遞送管，並且可藉由展開至一釋放或部署構形而與該遞送管脫離。該拉線可具有可接合該釋放部件的一延伸部分及可被拉動以與該釋放部件脫離的一細長部分。一旦植入該編織植入物，便可藉由使該拉線自該釋放部件脫離並且使該釋放部件自該遞送管脫離而將該編織植入物自該遞送管釋放。

Description

栓塞編織物的遞送系統
本揭露係關於醫療器械，更具體地，係關於用於動脈瘤治療裝置的遞送系統。
動脈瘤可係複雜且難以治療的。例如，當動脈瘤位於關鍵組織附近時，治療通路可能受到限制或不可用。此類因素與顱內動脈瘤有關，因為顱內血管周圍存在腦組織。
先前解決方案已包括血管內治療通路，據此動脈瘤囊的內部體積被移除或排除在動脈血壓及血流之外。血管內或其他外科手術方法的替代方案可包括閉塞裝置，該閉塞裝置用栓塞材料填充動脈瘤的囊以產生血栓性腫塊，或治療動脈瘤的入口(或頸部)以最小化穿過入口的血流，引起動脈瘤中的靜脈淤滯，並促進動脈瘤內血栓性腫塊的自然形成。此類裝置通常利用多個栓塞線圈來填充囊或治療入口。
通過用栓塞線圈填充動脈瘤囊而獲得足以閉塞動脈瘤的填充密度是困難且耗時的，並且動脈瘤形態(例如，寬頸部、分叉等)等需要輔助裝置(例如支架或球囊)來支撐線圈質量並獲得所需的填充密度。
與填充有栓塞線圈的動脈瘤腫塊相比，藉由用栓塞線圈治療動脈瘤的入口而形成的自然形成的血栓性腫塊可藉由減少從動脈壁的可能擴張並允許沿著頸部平面重新整合為原始載瘤血管(parent vessel)形狀來改善癒合。然而，遞送至動脈瘤頸部的栓塞線圈可能具有阻礙相鄰血管中的血 液流動的不利影響；同時，如果入口的填充不充分，血流可持續進入動脈瘤中。
此外，栓塞線圈並不總是能夠有效地治療動脈瘤，因為用多個線圈治療的動脈瘤經常由於捲繞不良、在動脈瘤頸部上缺乏覆蓋、血流或甚至動脈瘤尺寸而重新疏通或壓緊。
在美國專利第8,998,947號中描述了閉塞裝置的幾個實例。然而，這種方法依賴於栓塞線圈的使用或模擬線圈方法以獲得安全的填充密度，因此不必要地冒著動脈瘤破裂的風險。此外，該方法未能教導如下遞送系統，在該遞送系統中，閉塞裝置在其動脈瘤閉塞結構的初始定位之後可重新定位，以確保患者與精確定位相關的安全性。
因此期望具有這樣的裝置，其能輕鬆、準確且安全地閉塞載瘤血管中的動脈瘤頸或其他動靜脈畸形，而不會閉塞流入與載瘤血管連通的穿支血管的血流。
此外，一旦被部署至動脈瘤中，外科醫生就需要確認裝置已被明確地釋放。某些先前技術的釋放機構在分離時遇到困難，導致裝置的錯誤置放。
本文揭示可解決上述需要的本發明的各種例示性裝置及系統。該等裝置通常可包括附接至一釋放部件的一編織植入物，該釋放部件可與一遞送管及一拉線可拆卸地接合。該釋放部件可以一壓縮構形接合該遞送管，並且可藉由展開至一釋放或部署構形而與該遞送管脫離。拉線可具有可接合該釋放部件的一延伸部分及可被拉動以與該釋放部件脫離的一細長部分。一旦植入該編織植入物，便可藉由使該拉線自該釋放部件脫離並且使該釋放部件自該遞送管脫離而將該編織植入物自該遞送管釋放。
在一個實例中，一系統可包括一編織植入物、一遞送管、一釋放部件、及一拉線。該遞送管可具有穿過其的一內腔、一遠端、一外表面及該外表面上的一通道。該釋放部件可具有一帶及附接至該帶的一彈簧構件。該帶可附接至該編織植入物的一第一部分，並且該彈簧構件可從壓制該遞送管的該外表面的一壓縮構形及遠離該遞送管的該外表面延伸的一延伸構形移動。該拉線可定位在該遞送管的該通道內，並且可從一接合構形移動至一釋放構形。該接合構形可接合該釋放部件，並且該釋放構形可允許該彈簧構件展開至其延伸構形。
該編織植入物可具有由一折疊部分開的一第一部分及一第二部分。該第一部分可包圍該遞送管的該遠端的該外表面的一部分。該第二部分可具有一細長的管狀結構並且可定位在該遞送管的該內腔內。
該拉線可具有一延伸部分及一細長部分，並且該細長部分的移動可將該延伸部分從該接合構形移動至該釋放構形。該拉線可用黏著劑緊固至該遞送管的該通道，並且該細長部分的移動可破壞該黏著劑以鬆脫該拉線。
該系統可包括一附連部件，該附連部件將該編織植入物附連至該釋放部件的該帶的該外表面。該附連部件可包括穿過其中的一內腔。該內腔可包圍該釋放部件的該帶。
該彈簧構件可以是具有一近端及一遠端的一細長構件。該近端可附接至該釋放部件的該帶的一遠側表面。該遠端可以該壓縮構形壓制該遞送管的該外表面，並且該遠端可以該延伸構形遠離該遞送管的該外表面延伸。
該釋放部件可具有附接至該帶的一閉塞構件，該閉塞構件可從一遞送構形移動至一部署構形。該遞送構形可沿著該遞送管的該外表面縱向延伸，並且該部署構形可至少部分地阻塞該帶的該內腔。
該釋放部件可由不透射線(radiopaque)材料構成。
用於治療動脈瘤的例示性裝置可具有一管狀遞送構件、一編織管狀植入物、一釋放部件、及一彎曲構件。該管狀遞送構件可具有一遠側遞送端、一內部、及一外部。該編織管狀植入物可具有一遠側植入物端，該遠側植入物端可從該管狀遞送構件的該遠側遞送端向外延伸，並且朝近側折疊在該管狀遞送構件的該外部的一部分上。該編織管狀植入物可具有可定位在該管狀遞送構件的該內部的一近側植入物端。該釋放部件可附接至該編織植入物的該遠側植入物端，並且可拆卸地附接至靠近該遠側遞送端的該管狀遞送構件的該外部。該彎曲構件可定位在該管狀遞送構件的該遠側遞送端附近。該彎曲構件可具有一彎曲構形及一直線構形。該彎曲構形可接合該釋放部件的一遠側表面，並且該直線構形可與該釋放部件的該遠側表面脫離。
該釋放部件可具有一附接構形及一部署構形。該附接構形可接合該管狀遞送構件的該外部，並且該部署構形可與該管狀遞送構件的該外部脫離。
該部署構形可至少部分地使該釋放部件的該帶的該內腔閉塞。
該彎曲構件可以是一拉線的該延伸部分，並且該拉線的一細長部分的移動可將該延伸部分從該彎曲構形移動至該直線構形。該拉線可定位在該管狀遞送構件的該外部上的一通道內。該拉線可用黏著劑緊固至該管狀遞送構件，並且該細長部分的移動可破壞該黏著劑以鬆脫該拉線。
用於在一動脈瘤治療部位釋放一植入物的例示性方法可包括以下步驟：提供一編織植入遞送系統，將該遞送系統的一拉線接合至該遞送系統的一釋放部件，將該釋放部件接合至該遞送系統的一遞送管，將該遞送系統的一編織植入物植入在治療部位，拉動該拉線以自該釋放部件脫離，使該釋放部件自該遞送管脫離，並自該遞送管釋放該釋放部件，從而自該遞送管釋放該編織植入物。
釋放該釋放部件的該步驟可包括以下步驟：將該釋放部件的一彈簧構件從接合該遞送管的一外表面的一接合構形移動至遠離該遞送管的該外表面延伸的一釋放構形。
植入該編織植入物的該步驟可包括藉由反轉該編織植入物的一部分來形成一閉塞囊袋。
該方法可包括用黏著劑將該拉線緊固至該遞送管的步驟。拉動該拉線的該步驟可包括破壞該黏著劑的步驟。
該方法可包括移動該釋放部件的一可動構件以至少部分地使該釋放部件的一內腔閉塞的步驟。
10‧‧‧動脈瘤
12‧‧‧動脈瘤囊
14‧‧‧壁
110‧‧‧釋放部件
112‧‧‧帶
114‧‧‧遠側表面
116‧‧‧內腔
118‧‧‧外表面
120‧‧‧彈簧構件
122‧‧‧遠端
130‧‧‧閉塞構件
150‧‧‧附連部件
156‧‧‧內腔
158‧‧‧外表面
200‧‧‧拉線
202‧‧‧延伸部分
204‧‧‧細長部分
250‧‧‧黏著劑
300‧‧‧編織植入物
302‧‧‧外折疊部
303‧‧‧折疊部/折疊邊緣
304‧‧‧內折疊部
306‧‧‧彈出部分
308‧‧‧閉塞囊袋
310‧‧‧栓塞填料編織物
312‧‧‧編織植入物近端
500‧‧‧遞送管
502‧‧‧通道
504‧‧‧內腔
505‧‧‧近端
506‧‧‧遠端
508‧‧‧外表面
600‧‧‧遞送導管/微導管
602‧‧‧遠端
700‧‧‧方法
710-770‧‧‧步驟
800‧‧‧方法
810-870‧‧‧步驟
參見以下具體實施方式並結合圖式進一步討論本發明的上述態樣和進一步態樣，在圖式中，相同的編號指示各種圖中相同的結構元件和特徵。
圖式未必按比例繪製，相反，將重點放在繪示本發明的原理。圖式僅以舉例方式而非限制方式描繪本發明裝置的一或多種實施方案。
圖1a為描述本發明的一例示性裝置的部件的分解圖；
圖1b為本發明的一例示性裝置的剖視圖；
圖1c為本發明的一例示性裝置的截面圖；
圖2a至圖2g繪示使用本發明的裝置的方法；
圖3a及圖3b為剖視圖，繪示根據本發明的動脈瘤植入的各個階段的編織植入物；
圖4a至圖4c繪示根據本發明的一釋放部件；
圖5a為本發明的一例示性裝置的剖視圖；
圖5b為本發明的一例示性裝置的截面圖；
圖6為本發明的一例示性裝置的截面圖；
圖7a至圖7c為根據本發明的處於各種植入階段的一例示性裝置的剖視圖；
及
圖8及圖9為概述使用根據本發明的裝置的例示性方法步驟的流程圖。
利用栓塞線圈的先前方法可藉由治療動脈瘤入口及/或用栓塞編織植入物填充動脈瘤來改善。例如，參見以引用方式併入本文的美國專利申請案第15/903,860號。用編織植入物治療動脈瘤可具有優於利用栓塞線圈治療的潛在優點，諸如較高的填充密度、能在植入手術期間回縮及重 新定位植入物、能在沒有輔助裝置(諸如支架或球囊)的情況下進行植入、降低重新分析或壓緊的風險，以及改善整個動脈瘤頸部的覆蓋範圍。
在編織植入物遞送系統中，可能有利的是在植入物與遞送系統之間保持附接，直到植入物在治療部位處就位，然後分離植入物以便能夠將遞送系統取出。本揭露描述了可用於至少這一目的的各種例示性系統、裝置、及方法。
圖1a至圖1c繪示被構形成用於通過微導管遞送至治療部位的一例示性遞送系統。圖1a為描繪例示性遞送系統的部件的分解圖。圖1b為描繪包括圖1a所示部件的經組裝例示性遞送系統的剖視圖。圖1c為圖1b的經組裝系統的橫截面俯視圖。如圖所示，系統可包括一編織植入物300、一釋放部件110、一附連部件150、一遞送管500、及一拉線200。
編織植入物300可具有實質上管狀的結構，該結構具有將植入物300的一外折疊部302與植入物300的一內折疊部304分開的一折疊部303。植入物300可被折疊，使得內折疊部304的尺寸被設計為適配在遞送管500的一內腔504內，折疊邊緣303在遞送管500的一遠端506上捲起，並且外折疊部302適配在遞送管500上方而朝近側延伸並附接至釋放部件110。
釋放部件110可附接至編織植入物300的外折疊部分302，並且可用於在遞送至治療部位期間及植入期間將編織植入物300附接至遞送管500。植入完成後，釋放部件110可釋放遞送管，使得其可從患者體內取出。
圖1a至圖1c顯示處於一壓縮構形的一實例釋放部件110，該壓縮構形可使得釋放部件110能夠將編織植入物300附接至遞送管500。如圖1a至圖1c所示般配置，編織植入物300的外折疊部分302可折疊在釋放部件110上並附接至釋放部件110的一帶112。帶112可具有包括一外表面118及一內腔116的一管狀結構，然而可設想其他形狀。釋放部件110可包括從帶 延伸並且抵靠遞送管500的一外表面508壓制的一或多個彈簧構件120，從而在釋放部件110與遞送管500之間提供摩擦配合。彈簧構件120可從帶的一遠側表面114朝遠側延伸並且具有抵靠遞送管500壓制的遠端122。
一附連部件150可用於將釋放部件110附接至編織植入物300。附連部件150可具有一外表面158及一內腔156。附連部件150可被放置在釋放部件110的帶112上，從而將編織植入物300的外折疊部302的一部分固定在附連部件150與釋放部件110之間。
遞送管500可具有穿過其中的一內腔504。內腔504可含有編織植入物300的內折疊部304。內腔亦可含有額外元件以有利於植入編織植入物300(未圖示)。
遞送管500可具有在外表面508上縱向行進的一通道502，並且拉線200可定位在通道502內。拉線200可具有可接合釋放部件110的一延伸部分202(諸如鉤)及可定位在通道502內並朝近側延伸的一細長部分204。如圖所示，延伸部分202可跨帶112的遠側表面114延伸。延伸部分202與釋放部件的接合可防止釋放部件110相對於遞送管500的遠側移動，並且藉此可保持編織植入物300與釋放部件110之間的附接，直到編織植入物300的植入完成。
拉線200的細長部分204可朝近側延伸超過遞送管500的近端505，從而使系統的操作者能夠觸及拉線200。如圖1b所示，拉線200可用黏著劑250可拆卸地附接至遞送管500。黏著劑250可抑制拉線200的移動，直到向拉線200施加足夠的力以破壞黏著劑250。
圖1c繪示靠近遞送管的遠端506的系統的截面圖，近側折疊部303朝近側觀察，如圖1b所示。編織植入物300的內折疊部304可定位在遞送管500的內腔504的內部；釋放部件110可定位在遞送管500的外表面508之上；彈簧構件120可從釋放部件110的帶112的一遠側表面114延伸；外折疊部分302可適配於釋放部件110上，從而附接至釋放部件的帶112；並且 一附連部件150可適配在釋放部件的帶112及編織植入物300的外折疊部302的一部分上，從而將編織植入物300附連至釋放部件110。
圖2a至圖2g繪示用根據本發明的一系統或裝置部署一編織植入物300的一方法。圖2a繪示可提供的一編織植入物遞送系統或裝置。系統可包括一編織植入物300、一遞送管500、一釋放部件110、及一拉線200。該系統可如參考圖1a至圖1c所述進行組裝，使得拉線200與釋放部件110接合，並且釋放部件110接合至遞送管500。可經由一遞送導管600(諸如微導管)將經組裝的系統遞送至動脈瘤治療部位。
一旦被遞送，就可以例如如美國專利申請案第15/903,860號中所述部署編織植入物300。圖2b繪示具有從遞送導管600的遠端602射出的一彈出部分306的編織植入物300。如圖所示，編織植入物300可保持附接至遞送系統，使得外折疊部302的至少一部分保持在導管600內。只要釋放部件110保持附接至遞送管500，編織植入物300就可保持附接至遞送管500。在完成編織植入物的植入之前，可回縮並重新定位編織植入物300的彈出部分306。
圖2c繪示在植入完成後可採取的步驟，以將釋放部件110從遞送管500釋放，從而將編織植入物300從遞送管500釋放。圖2c顯示從釋放部件110脫離的拉線200及開始移動至一釋放構形的釋放部件110。
拉線200的延伸部分202可為可撓的，並且在將拉線200的細長部分204朝近側拉動時，延伸部分202可與釋放部件110脫離。一旦脫離，拉線200就能夠移動，以便不抑制釋放部件110(相對於遞送管)的遠側移動。
彈簧構件120的遠端122可遠離遞送管500延伸，從一壓縮構形移動至一延伸構形。當彈簧構件120處於壓縮構形時，彈簧構件120可防止釋放部件110相對於遞送管500移動。彈簧構件120可由鎳鈦諾(Nitinol)或其他記憶形狀材料製成，使得在接觸體液諸如血液時，彈簧構件120可移動 至遠離遞送管500延伸的預定形狀。圖2c顯示遞送管500相對於導管朝遠側移動，使得遞送系統開始退出導管600，從而暴露彈簧構件120的遠端122。
圖2d繪示彈簧構件120在退出導管600後繼續移動至一釋放構形。彈簧構件120可壓抵編織植入物300，從而延伸植入物300的部分，例如以使治療部位開口閉塞，諸如動脈瘤的頸部。
圖2e繪示從遞送管500的遠端506滑出的釋放部件110。圖2f為如圖2e所示朝近側觀察的截面圖。當彈簧構件120向外延伸時，釋放部件110的帶112顯示為包圍遞送管500的遠端506。
圖2g繪示與遞送管500分開的釋放部件110。一旦脫離，可在編織植入物300及釋放部件110保持植入的同時取出遞送管500。
圖3a及圖3b是繪示在動脈瘤10中植入的不同階段的一編織植入物300的剖視圖。圖3a繪示被部分地部署至血管20的動脈瘤10中但尚未從其遞送系統釋放的一編織植入物300。導管600已被遞送至動脈瘤10的部位。如圖所示，編織植入物300可形成經定尺寸以延伸至動脈瘤10的壁14的一閉塞囊袋308。編織植入物300的未形成閉塞囊袋308的部分可保持管狀形狀，該管狀形狀可被填充至動脈瘤囊12中，從而形成一栓塞填料編織物310。圖3a繪示部分地部署的栓塞填料編織物310，使得編織物的一部分保留在遞送系統中。在一部分部署狀態中，編織物310可被回縮回遞送管500中，重新定位並重新部署。在回縮、重新定位、及重新部署期間，釋放部件110可保持附接至遞送管500或與該遞送管接合，從而保持編織植入物300與遞送系統之間的附接。
圖3b繪示所部署的植入物300。釋放部件110可保持附接至編織植入物300，並且一旦植入就可駐留在動脈瘤10的頸部處。釋放部件110可具有彈簧構件120或向外延伸的其他結構，從而在動脈瘤10的頸部展開閉塞囊袋308。
圖4a至圖4c繪示一釋放部件110的另一個實例。如圖所示，釋放部件110可具有閉塞構件130。圖4a繪示處於經定尺寸以適配在一遞送管500上並行進穿過一微導管600的一構形的釋放部件110。圖4b為圖4a中以一例示性部署構形示出的釋放部件110的側視圖。圖4c為處於部署構形的釋放部件110的俯視圖。處於部署構形時，閉塞構件130可向內彎曲，至少部分地閉塞釋放部件110的內腔116。如關於彈簧構件120所述，閉塞構件130可由可撓性材料構成及/或可由記憶金屬諸如鎳鈦諾構成。閉塞構件130可在處於遞送構形時變形，並且在處於部署構形時移動至一預定的形狀。當閉塞構件130接觸血液或其他體液時，可藉由溫度變化促使從該變形移動至該預定的形狀。
釋放部件110可被導向成使得由閉塞構件130使釋放部件110的內腔116閉塞不會導致閉塞構件130阻止釋放部件110與遞送管500脫離及分開。如圖所示，閉塞構件130可附接至帶112的近側，並且彈簧構件120可附接至遠側。正因為如此導向，在離開微導管600時，彈簧構件120可接觸血液或體液，並且因此使遞送管500脫離。同時，導管600可在閉塞構件130與血液或流體之間提供屏障。然後可在閉塞構件130接觸血液或體液之前取出遞送管500。一旦遞送管500被取出，則可取出遞送導管600，從而將閉塞構件130暴露於血液或流體，從而使閉塞構件130回縮以使帶112的內腔116閉塞。
圖5a顯示在導管600的剖面前方的裝置的外部。一拉線200定位在一遞送管500的一外表面508上的一通道502內。拉線200在釋放部件110的下方延伸以接合釋放部件110。一編織植入物300用一附連部件150附接至釋放部件110，並且被折疊成使得一外折疊部分302定位在遞送管500上方且一折疊部303定位在遞送管500的一遠端上方。
圖5b顯示如圖5a所示的系統的截面圖。圖5b顯示遞送管500、遞送管通道502、拉線200、釋放部件110的帶112、編織植入物300的外折疊部分302、附連部件150、及導管600的可能定位。
圖6是處於圖5a及圖5b所示構形的裝置及導管600的截面圖。在截面圖中，可看見遞送管500的內部或內腔504、編織植入物300的近端312、以及拉線200、遞送管通道502、釋放部件110、附連部件150、編織植入物內折疊部304、遞送管500、以及編織植入物外折疊部302的橫截面。拉線200的延伸部分202顯示為接合釋放部件110的帶112，並且彈簧構件120顯示為從釋放部件110的帶112朝遠側延伸。拉線200可另外延伸以接合編織植入物300。
圖7a至圖7c為在植入編織植入物300之後的各個階段的例示性裝置的剖視圖，繪示從一遞送系統釋放編織植入物300。圖7a至圖7c顯示一遞送管500、遞送管通道502、拉線200、釋放部件110、附連部件150、編織植入物近端312、及閉塞囊袋308的橫截面。在圖7a所示的階段，編織植入物300已從遞送管500射出，並且編織植入物300開始與遞送系統分離。遞送管500的遠端506朝遠側延伸出遞送導管600，並且彈簧構件120延伸而遠離遞送管。拉線200可利用一延伸部分202接合釋放部件110，從而抑制釋放部件110的遠側移動。
在圖7b所示的階段，拉線200已與釋放部件110脫離。延伸部分202可由可撓性材料製成，該可撓性材料可回應於力而拉直，使得朝近側拉動拉線200的細長部分204導致延伸部分202從釋放部件110的帶112的遠側表面114回縮並拉直以適配在釋放部件110的帶112下方的遞送管的通道502內。一旦拉線200與釋放部件110如圖7b所示脫離並且彈簧構件120延伸而遠離遞送管500，釋放部件110就能夠自由地從遞送管500的遠端506滑出。
在圖7c所示的階段，編織植入物300已與遞送管500分離。如圖所示，彈簧構件120可向外延伸以與編織植入物300並置。一旦分開，就能夠從患者體內取出導管600、拉線200、及遞送管500。
圖8及圖9為概述使用根據本發明的裝置的例示性方法步驟的流程圖。方法步驟可以藉由本文描述的例示性方式或藉由所屬技術領域中具有通常知識者已知的任何方式來實施。
參見圖8中概述的方法700，在步驟710中，可提供具有一編織植入物、一遞送管、一釋放部件、及一拉線200的一編織植入遞送系統。該編織植入物遞送系統可以是本文所述的任何遞送系統，其具有本文描述的特徵的任何組合、以及所屬技術領域中具有通常知識者已知的任何特徵。在步驟720中，可將拉線接合至釋放部件。在步驟730中，可將釋放部件接合至遞送管。在步驟740中，可將編織植入物植入治療部位處的動脈瘤中。在步驟750中，可拉動拉線以使拉線與釋放部件脫離。在步驟760中，釋放部件可自遞送管脫離。在步驟770中，釋放部件可從遞送管釋放，從而從遞送管釋放編織植入物。
參見圖9中概述的方法800，在步驟810中，可提供具有一編織植入物、一遞送管、一釋放部件、及一拉線的一編織植入物遞送系統。該編織植入物遞送系統可以是本文所述的任何遞送系統，其具有本文描述的特徵的任何組合、以及所屬技術領域中具有通常知識者已知的任何特徵。在步驟815中，拉線可利用黏著劑緊固至遞送管。在步驟820中，拉線可接合釋放部件。在步驟830中，釋放部件可接合遞送管。在步驟840中，可將編織植入物植入治療部位處的動脈瘤中，藉由反轉編織植入物的一部分來形成一閉塞囊袋。在步驟850中，黏著劑能夠被破壞，並且可藉由拉動拉線而使拉線自釋放部件脫離。在步驟860中，可藉由將一彈簧構件從接合遞送管的一外表面的一接合構形移動至延伸而遠離遞送管的外表面的一釋 放構形而使釋放部件自遞送管脫離。在步驟870中，釋放部件可從遞送管釋放，從而從遞送管釋放編織植入物。
本文所包含的描述是說明本發明的實例，並且不旨在限制本發明的範圍。如本文所述，本發明設想到可用於在動脈瘤中釋放一編織植入物300的一系統、裝置或方法的許多變化型及修改。舉例而言，變化型可包括但不限於本文所述元件及部件的替代性幾何形狀、針對每個部件或元件利用各種材料中的任一種(例如，不透射線材料、記憶形狀金屬等)、利用包括用於將編織植入物300定位在治療部位處或從遞送管500的內部排出編織植入物300的一部分的部件的額外部件、利用額外部件來執行本文所述的功能，或者利用額外部件來執行本文未描述的功能。這些修改將對本發明所屬技術領域中具有通常知識者顯而易見，並且旨在處於以下申請專利範圍的範疇內。
110‧‧‧釋放部件
112‧‧‧帶
116‧‧‧內腔
118‧‧‧外表面
120‧‧‧彈簧構件
122‧‧‧遠端
150‧‧‧附連部件
156‧‧‧內腔
158‧‧‧外表面
200‧‧‧拉線
202‧‧‧延伸部分
204‧‧‧細長部分
300‧‧‧編織植入物
302‧‧‧外折疊部
303‧‧‧折疊部/折疊邊緣
304‧‧‧內折疊部
500‧‧‧遞送管
502‧‧‧通道
504‧‧‧內腔
506‧‧‧遠端
508‧‧‧外表面

Claims (19)

  1. 一種用於在動脈瘤中釋放一植入物的系統，該系統包含：
    一編織植入物；
    一遞送管，該遞送管包含穿過其中的一內腔、一遠端、一外表面、及設置在該外表面上的一通道；
    一釋放部件，該釋放部件包含：
    一帶，該帶包含一外表面及一內腔，該外表面附接至該編織植入物的一第
    一部分，該內腔包圍該遞送管而鄰近該遞送管的該遠端，及
    一彈簧構件，該彈簧構件附接至該帶，該彈簧構件可從一壓縮構形移動至
    一延伸構形，該壓縮構形壓制該遞送管的該外表面，且該延伸構形延伸而遠離該遞送管的該外表面；及
    一拉線，該拉線定位在該遞送管的該通道內，該拉線可從一接合構形移動至一釋放構形，該接合構形接合該釋放部件，且該釋放構形允許該彈簧構件展開至其延伸構形。
  2. 如請求項1所述之系統，
    其中該編織植入物的該第一部分藉由一折疊部而與該編織植入物的一第二部分分開，
    其中該第一部分包圍該遞送管的該遠端的該外表面的一部分，且
    其中該第二部分包含一細長管狀結構且定位在該遞送管的該內腔內。
  3. 如請求項1所述之系統，其中該拉線包含一延伸部分及一細長部分，其中該細長部分的移動使得該延伸部分從該接合構形移動至該釋放構形。
  4. 如請求項3所述之系統，其中該拉線係用黏著劑緊固至該遞送管的該通道，且其中該細長部分的移動破壞該黏著劑以鬆脫該拉線。
  5. 如請求項1所述之系統，其進一步包含將該編織植入物附連至該帶的該外表面的一附連部件，該附連部件包含穿過其中的一內腔，該內腔包圍該帶。
  6. 如請求項1所述之系統，其中該彈簧構件為一細長構件，該細長構件包含一近端及一遠端，該近端附接至該帶的一遠側表面，該遠端以該壓縮構形壓制該遞送管的該外表面，且該遠端以該延伸構形延伸而遠離該遞送管的該外表面。
  7. 如請求項1所述之系統，其中該釋放部件進一步包含附接至該帶的一閉塞構件，該閉塞構件可從一遞送構形移動至一部署構形，該遞送構形沿著該遞送管的該外表面縱向延伸，且該部署構形至少部分地阻塞該帶的該內腔。
  8. 如請求項1所述之系統，其中該釋放部件包含不透射線(radiopaque)材料。
  9. 一種用於治療動脈瘤的裝置，該裝置包含：
    一管狀遞送構件，該管狀遞送構件包含一遠側遞送端、一內部、及一外部；
    一編織管狀植入物，其包含：
    一遠側植入物端，該遠側植入物端從該管狀遞送構件的該遠側遞送端向外延伸且在該管狀遞送構件的該外部的一部分上朝近側折疊，及
    一近側植入物端，該近側植入物端定位在該管狀遞送構件的該內部內；
    一釋放部件，該釋放部件附接至該遠側植入物端且可拆卸地附接至該管狀遞送構件的鄰近該遠側遞送端的該外部；及
    一彎曲構件，該彎曲構件經定位成鄰近該管狀遞送構件的該遠側遞送端，該彎曲構件包含一彎曲構形及一直線構形，該彎曲構形接合該釋放部件的
    一遠側表面，且該直線構形係與該釋放部件的該遠側表面脫離。
  10. 如請求項9所述之裝置，其中該釋放部件包含一附接構形及一部署構形，該附接構形接合該管狀遞送構件的該外部，且該部署構形係與該管狀遞送構件的該外部脫離。
  11. 如請求項10所述之裝置，其中該部署構形至少部分地閉塞該帶的該內腔。
  12. 如請求項9所述之裝置，其中該彎曲構件為一拉線的一延伸部分，且其中該拉線的一細長部分的移動使得該延伸部分從該彎曲構形移動至該直線構形。
  13. 如請求項12所述之裝置，其中該拉線定位在該管狀遞送構件的該外部上的一通道內。
  14. 如請求項12所述之裝置，其中該拉線係用黏著劑緊固至該管狀遞送構件，且其中該細長部分的該移動破壞該黏著劑以鬆脫該拉線。
  15. 一種用於在動脈瘤治療部位處釋放一植入物的方法，該方法包含：
    提供一編織植入遞送系統，其中該植入遞送系統包含一編織植入物、一遞送管、一釋放部件、及一拉線；
    將該拉線接合至該釋放部件；
    將該釋放部件接合至該遞送管；
    將該編織植入物植入在該治療部位處；
    拉動該拉線以自該釋放部件脫離；
    使該釋放部件自該遞送管脫離；及
    從該遞送管釋放該釋放部件，從而從該遞送管釋放該編織植入物。
  16. 如請求項15所述之方法，其中釋放該釋放部件的該步驟進一步包含以下步驟：將該釋放部件的一彈簧構件從接合該遞送管的一外表面的一接合構形移動至延伸而遠離該遞送管的該外表面的一釋放構形。
  17. 如請求項15所述之方法，其中植入該編織植入物的該步驟進一步包含藉由反轉該編織植入物的一部分來形成一閉塞囊袋。
  18. 如請求項15所述之方法，其進一步包含用黏著劑將該拉線緊固至該遞送管的步驟；且其中拉動該拉線的該步驟進一步包含破壞該黏著劑的步驟。
  19. 如請求項15所述之方法，其中該釋放部件包含一內腔及一可移動構件，該方法進一步包含移動該構件以至少部分地閉塞該內腔的步驟。
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