TW201334872A - Disposable printhead module for biomedical detection - Google Patents

Abstract

A disposable printhead module for biomedical detection comprises a base and a bottle. The base has a printhead module disposed therein, and has a puncturing component, a securing component and an isolating component disposed thereon. The bottle is used for containing a fluid and has an opening, which is sealed by a membrane. When the bottle is mounted on the base, the membrane of the bottle is corresponding to the puncturing component of the base, and the opening of the bottle is engaged with the securing component of the base, so that the puncturing component penetrates through the membrane, the fluid in the bottle flows to the printhead module through the puncturing component, and the isolating component conducts the clean gas into the bottle to adjust the inner pressure of the bottle, so as to enable the printhead module to eject microdroplets.

Description

Discarding nozzle module for biomedical testing

This case relates to a disposable nozzle module, in particular to a biomedical test, and can avoid the detection liquid being polluted by the outside, thereby achieving a non-toxic, sterile, labor-saving, time-saving and disposable group can be discarded after use. Nozzle module.

As medical quality is gradually taken seriously, the efficiency and accuracy of biomedical testing has become a part that cannot be ignored. Fast and accurate test reports can assist in the early detection of many diseases for subsequent treatment. In the current biomedical testing system, the inspector first extracts the test agent into the syringe, and then drops the test agent into the tube to be tested, and performs the screening test and the analysis result. However, the biomedical detection method is not only time-consuming. The amount of liquid droplets of the detection agent is easily controlled by the inspector's inconsistent force applied to the syringe. On the other hand, the inspectors must look forward to working in the workplace, and the types of testing agents and tubes to be tested are also numerous. Therefore, the inspectors are inadvertently inadvertently dropping the wrong testing agents into the tubes to be tested, which is prone to detection errors or The detection of cross-infection of the drug causes the analysis result to be distorted, and the inspector is also required to bear the risk of human error.

Or, some test items require a large number of test samples, and each of the test samples is small in quantity and time-sensitive, for example, a human blood sample is used for testing, and in this case, in order to take care of the blood sample test. Effectiveness, it is necessary to complete the accurate test of many samples in a certain period of time. If the traditional artificial biochemical or biomolecular detection method is still used in this case, it will take time to test the artificial one-by-one test agent. Moreover, it is impossible to precisely control the amount of droplets of the detection agent, which may result in an error in the detection result or the inability to complete the detection operation in an effective time.

In view of this, how to develop a disposable nozzle module suitable for biomedical detection that can improve the above-mentioned conventional technology is an urgent problem to be solved.

One of the objectives of the present invention is to provide a disposable nozzle module suitable for biomedical testing, which uses the fastening portion on the base to engage and fix the opening of the receiving bottle, and is traversed by the puncture portion on the base. a diaphragm for accommodating the opening of the bottle, so that the liquid contained in the bottle can be guided to the nozzle assembly through the guiding portion of the bottle, and the cleaning gas is guided through the isolation component on the base to adjust the internal pressure of the bottle.微The droplets are ejected by the nozzle assembly to solve the problem of the time-consuming inspection of the prior art, the inaccurate control of the droplet amount of the solution solution, the distortion of the analysis result due to human error, and the avoidance of the drug solution in the drug bottle. It is polluted by the outside world, and thus achieves the purpose of non-toxic, sterilized, labor-saving, time-saving and can be discarded after use.

In order to achieve the above objective, one of the present invention provides a disposable nozzle module suitable for biomedical detection, comprising: a base having a nozzle assembly therein, and having a puncture portion and a fastening portion thereon And a spacer component; and a receiving bottle for accommodating the liquid, and having an opening, the opening is sealed by a diaphragm; wherein, when the receiving bottle is disposed on the base, the diaphragm of the receiving bottle corresponds to the puncturing portion of the base And the opening of the receiving bottle is clamped on the fixing portion of the base, so that the puncture portion passes through the diaphragm, and the liquid in the receiving bottle can flow to the nozzle assembly through the guiding of the puncture portion, and is isolated The assembly directs the clean gas to adjust the internal pressure of the contained bottle, and the droplets are ejected by the showerhead assembly.

Some exemplary embodiments embodying the features and advantages of the present invention are described in detail in the following description. It is to be understood that the present invention is capable of various modifications in the various aspects of the present invention, and the description and illustration are in the nature of

Please refer to FIG. 1 , which is a schematic view of the disposable nozzle module of the preferred embodiment of the present invention before assembly. As shown in the figure, the disposable nozzle module 1 includes a base 11 and a receiving bottle 12, and the base 11 is substantially a one-piece housing structure, but not limited thereto, and has an upper surface 111. The lower surface 112 and an inner space (not shown) are disposed opposite to the lower surface 112. In this embodiment, the pedestal 11 further includes a structure such as a puncturing portion 1111, a locking portion 1112, an isolating member 1113, and a head assembly (not shown), wherein the puncturing portion 1111, the locking portion 1112, and the isolation member 1113 are configured. The tipping portion 1111 can be, but is not limited to, a thimble structure, which has a substantially cylindrical structure and has a tip portion 1111a at the top thereof, but does not In some embodiments, the tip portion 1111a can be, but is not limited to, a conical structure, and has at least one hole 1111b at the top end of the tip portion 1111a. The hole 1111b can be coupled to the isolation assembly 1113 and the showerhead assembly. (not shown) is connected, but not limited to this.

Please refer to FIG. 1 . As shown in the figure, the locking portion 1112 can be, but is not limited to, a latch structure. In the embodiment, the locking portion 1112 is formed by a plurality of bumps, but The upper limit of the top surface 121 of the bottle 12 is correspondingly arranged in an annular manner to engage the top 121 of the receiving bottle 12 to accommodate the bottle. 12 fixed settings. In other embodiments, the locking portion 1112 can be, but is not limited to, a hook-like structure, and is hooked on the top portion 121 of the receiving bottle 12 for fixing. Thus, the locking portion 1112 can be seen. The type is not limited to the card structure of the embodiment, and may be changed depending on the actual application.

The isolation component 1113 can be, but is not limited to, a valve isolation structure, which is substantially a box structure, but not limited thereto, and has a filter assembly (not shown) therein for filtering external gas. The isolation component 1113 is in communication with the puncturing portion 1111, so that the filtered clean gas can be guided into the accommodating bottle 12 via the hole 1111b of the puncturing portion 1111 to adjust the internal pressure of the accommodating bottle 12.

In the embodiment, a head assembly (not shown) is disposed in an internal space (not shown) of the base 11 for controlling the liquid detecting operation of the disposable head module 1, and the head assembly (not shown) further has an orifice (not shown) which is disposed on the lower surface 112 of the base 11 and corresponds to an object to be tested (not shown). And spraying the detection liquid into the corresponding object to be tested (not shown), and causing the disposable nozzle module 1 to complete the liquid detecting operation.

Please refer to FIG. 2 , which is a schematic view of the appearance of the bottle in the preferred embodiment of the present invention. The interior of the receiving bottle 12 has an accommodating space (not shown) for accommodating a liquid. A detection liquid, for example, a related agent for biomedical examination, a biochemical reagent for biochemical detection, or a chemical reagent, etc., is not limited thereto, and the receiving bottle 12 has a top 121, and at the top 121 There is an opening 120 which is sealed by the diaphragm 122, so as to achieve the sealing effect of the detection liquid inside the bottle 12 without being polluted by the outside to maintain its aseptic state. In some embodiments, the diaphragm 122 is made of a soft rubber material and has flexibility, so that it can be deformed according to the abutment of the puncture portion 1111, and when the puncture portion 1111 pierces the diaphragm 122 and passes through the diaphragm 122. The deformation amount of the diaphragm 122 conforms to the crossing amount of the puncture portion 1111, so that the diaphragm 122 is in close contact with the puncture portion 1111, so that when the receiving bottle 12 is placed on the base 11, the sealing state is maintained. Therefore, the detection liquid inside does not seep onto the susceptor 11, but is directly guided by the hole 1111b at the top end of the puncturing portion 1111 and flows into the head assembly (not shown) in the susceptor 11, and the nozzle assembly (not shown) The injection hole (not shown) of the invention sprays the detection liquid out of the droplets.

Please refer to FIG. 1 and FIG. 3 at the same time. FIG. 3 is a schematic diagram of the assembled disposable nozzle module of the preferred embodiment of the present invention. As shown in the figure, when the accommodating bottle 12 is to be disposed on the susceptor 11, the diaphragm 122 of the accommodating bottle 12 is correspondingly disposed on the puncturing portion 1111 of the susceptor 11, and is clamped by the locking portion 1112 of the susceptor 11. The accommodating bottle 12 is fixedly fixed to the upper surface 111 of the pedestal 11 and corresponding to the diaphragm 122 of the accommodating bottle 12 by the tip portion 1111a of the puncturing portion 1111. The liquid in the receiving bottle 12 can be guided through the hole 1111b of the puncture portion 1111 to flow into the head assembly (not shown) of the base 11 and filter the external gas through the isolating assembly 1113 to filter the clean gas. It is guided into the accommodating bottle 12 via the hole 1111b of the puncturing portion 1111 to adjust the internal pressure of the accommodating bottle 12, thereby controlling the flow rate of the liquid in the accommodating bottle 12, and finally controlling the spraying of the head unit (not shown). The liquid velocity is such that the liquid in the head unit (not shown) can eject the droplets through the orifice (not shown), thereby preventing the liquid in the bottle 12 from being contaminated by the outside, thereby achieving non-toxic, sterile and labor-saving. Time-saving and after use, the whole group can be abandoned.

Therefore, in this case, the puncturing portion 111 of the susceptor 11 passes through the diaphragm 122 of the accommodating bottle 12, so that the liquid in the accommodating device 12 can be smoothly exported into the nozzle assembly (not shown), and the isolation assembly is utilized. 1113 filters the external gas and guides the filtered clean gas into the accommodating bottle 12 to adjust the internal pressure of the accommodating bottle 12, thereby controlling the flow rate of the liquid in the accommodating bottle 12, and by the nozzle assembly (not shown) The orifice (not shown) of the showerhead (not shown) ejects liquid from the showerhead assembly (not shown). In some embodiments, the nozzle assembly (not shown) has a droplet aperture of 0.05 to 200,000 pico- The meter can be sprayed with a droplet size of 0.1 to 2000 pico-liter, and the ejection droplet rate is 0 to 10000 drops/second, which is not limited thereto, thereby precisely controlling the amount of liquid droplets ejected.

In summary, the disposable nozzle module provided in the present invention mainly comprises a disposable base and a combined structure with the receiving bottle, and can be correspondingly disposed through the diaphragm of the receiving bottle by the puncture portion, and the diaphragm The amount of deformation conforms to the crossing amount of the puncture portion, so that it maintains the sealed state, and the isolation component disposed on the base is used to adjust the internal pressure of the receiving bottle, thereby controlling the size of the droplets ejected by the nozzle assembly. It can solve the problem that the conventional test takes time, the amount of liquid droplets of the chemical solution cannot be accurately controlled, and the analysis result is easily distorted due to human error, and the chemical solution in the pharmaceutical bottle can be prevented from being polluted by the outside, and the non-toxic, sterile and labor-saving is achieved. The purpose of saving time, and after the use, can be abandoned in the whole group, which is of great industrial use value.

The present invention has been described in detail by the above-described embodiments, and may be modified by those skilled in the art, without departing from the scope of the appended claims.

1. . . Discarding nozzle module

11. . . Pedestal

111. . . Upper surface

112. . . lower surface

1111. . . Puncture

1111a. . . Tip

1111b. . . Hole

1112. . . Carding department

1113. . . Isolation component

12. . . Container

120. . . Opening

121. . . top

122. . . Diaphragm

Figure 1 is a schematic view of the disposable nozzle module of the preferred embodiment of the present invention prior to assembly.

Figure 2 is a schematic view showing the appearance of the bottle for the preferred embodiment of the present invention.

Figure 3 is a schematic view of the disposable nozzle module of the preferred embodiment of the present invention after assembly.

1. . . Discarding nozzle module

11. . . Pedestal

111. . . Upper surface

112. . . lower surface

1111. . . Puncture

1111a. . . Tip

1111b. . . Hole

1112. . . Carding department

1113. . . Isolation component

12. . . Container

121. . . top

122. . . Diaphragm

Claims (10)

A disposable nozzle module suitable for biomedical testing, comprising:
a pedestal having a nozzle assembly therein, and having a puncturing portion, a fastening portion and an isolating assembly thereon; and a receiving bottle for accommodating a liquid and having an opening, the opening being The diaphragm is sealed;
Wherein, when the receiving bottle is disposed on the base, the diaphragm of the receiving bottle is disposed corresponding to the puncture portion of the base, and the opening of the receiving bottle is stuck to the base a securing portion, such that the puncture portion passes through the diaphragm, and the liquid in the receiving bottle can be guided to the showerhead assembly via the puncture portion, and a clean gas is guided through the isolation assembly to adjust the The internal pressure of one of the bottles is accommodated, and the droplets are ejected by the nozzle assembly. The disposable nozzle module for biomedical detection according to the first aspect of the invention, wherein the base has an upper surface and a lower surface corresponding to the upper surface, and the puncture portion, the fastening portion and The isolation component is disposed on the upper surface. The disposable nozzle module suitable for biomedical detection according to claim 2, wherein the nozzle assembly has a spray hole, and the spray hole is disposed on the lower surface. The disposable sprinkler module suitable for biomedical testing, as described in claim 1, wherein the puncture portion is a thimble. The disposable sprinkler module for biomedical testing, as described in claim 4, wherein the puncture portion has a tip portion that is conical to pass through the diaphragm. The disposable nozzle module suitable for biomedical detection according to claim 5, wherein the tip of the puncture portion has a hole, and the hole is disposed at the top end of the tip to accommodate the bottle. The liquid can be directed out through the hole. The discarding nozzle module suitable for biomedical testing, as described in claim 1, wherein the securing portion is a latching member for fixing the opening of the receiving bottle. The disposable nozzle module suitable for biomedical detection according to the first aspect of the patent application, wherein the diaphragm is made of a soft rubber material, such that the deformation amount conforms to the penetration amount of the puncture portion of the base. The disposable nozzle module suitable for biomedical detection, as described in claim 1, wherein the nozzle assembly has a droplet diameter of 0.05 to 200,000 pico-meter, and the droplet size can be 0.1 to 2000 pico. -liter, and the ejection rate is 0~10000 drops/second. The disposable nozzle module suitable for biomedical detection according to the first aspect of the invention, wherein the piercing portion and the isolating component communicate with each other, so that the isolating component transmits the clean gas to the puncture portion.