TW201329227A - Foamable alcoholic composition - Google Patents

Abstract

A stable foam composition includes greater than about 40 weight percent of an alcohol, based upon the total weight of the alcoholic composition, and a foaming surfactant selected from fluorosurfactants, siloxane polymer surfactants, and combinations thereof. When the foaming surfactant includes a fluorosurfactant, the alcoholic composition further includes a polymeric or oligomeric foam stabilizer.

Description

Foamable alcohol-containing composition

The present invention relates to a foamable alcohol-containing composition and, more particularly, to a foaming surfactant selected from the group consisting of fluorosurfactants, siloxane surfactants, and combinations thereof.

Foam cleaning products are popular, in part because they are easily spread on the surface. Consumers seem to prefer luxury soaps. Due in part to the larger surface area of the foam, less foam is required to produce the same cleaning power as a liquid or gel. Due to the high surface tension of the foam, properly formulated foam products do not produce the dripping and splashing experienced by conventional gel or liquid products. This prevents damage to the floor and equipment walls where the product dispenser is used. The manufacture of foam products may be easier than gel products, which are often incorporated into powdery thickeners that are difficult to handle.

Aqueous foam cleaning products have been described, for example, as a foam cleaning composition comprising a surfactant, a suds boosting agent such as glycol, and at least 80 weight percent (wt%) water.

Alcohol-containing products are popular as disinfectants for the skin. However, a foamed product based on an alcohol-containing composition is problematic because the alcohol is known to have strong defoaming properties. Although liquefied gas-based alcohol-containing foamy materials are available Yes, but these liquefied gas products are generally more expensive to manufacture than non-liquefied gas foams.

It is described that a stable foaming composition containing water and an alkoxylated oxirane may contain up to 30% by weight of an alcohol and may remain stable for one month or longer. However, the alcohol-containing composition does not exhibit effective antimicrobial properties unless the alcohol is present in an amount of 50% by weight or more.

A foamable liquid detergent containing a surfactant, a humectant, water and from about 35 to about 70% by weight of an alcohol has been described, however, the foam produced by exposure of this composition to air will be substantially within 5 to 45 seconds. Disintegrate into a liquid.

The skin disinfecting formulation is described as comprising: (a) from about 50 to about 80 weight percent of the total composition of the alcohol; (b) from about 0.02 to about 5 weight percent of the block copolymer; (c) from about 5% to about 25 weight percent % of a foaming surfactant; (d) from about 0% by weight to about 3% by weight of a thickener; (e) from about 1% by weight to about 5% by weight of an emulsifier; (f) from about 0% by weight to about 5% by weight of preservative; (g) from about 1% to about 10% by weight of detergent; (h) from about 0.5% to about 5% by weight of polyalkylene glycol; (i) about 0.05% by weight to About 5% by weight of a wetting agent and/or softening agent; and (j) from about 6% by weight to about 30% by weight of water. The foaming surfactants taught are aliphatic ammonium succinate sulfonate, coconut decylamine, amine amides such as coconut oil diethanolamine, amine oxides such as hexadecyl dimethylamine oxide, and the like. Amphoteric acid such as siostereoamphoro-pionate and lauryl propyl betaine surfactant.

Commercially available non-liquefied gas alcohol-containing foamy materials have been utilized The fluoroalkyl ester surfactant is formulated and dispenses with the foaming pump mechanism. However, the foam thus produced flies and will immediately shrink or liquefy into a thin aqueous layer. When the alcohol-containing foam is dispensed from a conventional foaming pump mechanism, some of the foam will remain in the dispenser tube and, when the foam breaks, the composition will often drip out of the dispenser. This dripping not only wastes the product, making the area around the dispenser look unsanitary and may cause damage to the walls and floors, and if the product drops to the ground, it will cause a side slip hazard. Therefore, a stabilized foamable alcohol-containing composition is required.

One or more specific embodiments of the present invention provide a foamable alcohol-containing composition comprising at least about 40 weight percent alcohol based on the total weight of the alcohol-containing composition; and selected from the group consisting of siloxane polymers a foaming surfactant of a surfactant, an anionic, a cationic and a zwitterionic fluorosurfactant, and combinations thereof; with the proviso that when the foaming surfactant comprises a fluorosurfactant, the foamable The alcohol composition further comprises a polymeric or oligomerized foam stabilizer.

One or more embodiments of the present invention further provide an antimicrobial composition comprising at least about 40 weight percent of an alcohol based on the total weight of the alcohol-containing composition; and a surfactant selected from the group consisting of a siloxane polymer surfactant a foaming surfactant of an anionic, cationic and zwitterionic fluorosurfactant and combinations thereof; with the proviso that when the foaming surfactant comprises a fluorosurfactant, the foamable alcohol-containing composition Further comprising a polymeric or oligomeric foam stabilizer.

One or more specific examples of the present invention further provide a form of stability A method for forming an alcohol-containing foam comprising a combination of an alcohol, a surfactant selected from the group consisting of a siloxane surfactant, an anionic, a cationic and a zwitterionic fluorosurfactant, and combinations thereof to form a foamable surfactant Soaking the alcohol-containing composition; mixing the alcohol-containing composition and air or a passive gas in a mixing chamber to form a mixture; and passing the mixture through a screen to form a foam, at least the foamed alcohol-containing composition comprising at least about 40 The weight percent alcohol is based on the total weight of the alcohol-containing composition, with the proviso that when the foaming surfactant comprises a fluorosurfactant, the foamable alcohol-containing composition further comprises polymerization or oligomerization. Foam stabilizer.

One or more embodiments of the present invention further provide a method of reducing the dripping of a composition from a foam pump dispenser suitable for dispensing the composition, the method comprising providing a foamable composition comprising the Based on the total weight of the alcohol composition, at least about 40% by weight of the alcohol, based on the total weight of the alcohol-containing composition, and selected from the group consisting of a siloxane polymer surfactant, anionic, cationic and zwitterionic a foaming surfactant of a fluorosurfactant and combinations thereof, with the proviso that when the foaming surfactant comprises a fluorosurfactant, the foamable alcohol-containing composition further comprises a polymeric or oligomeric foam stabilizer; A foam pump dispenser having a dispenser head is provided; and the foamable composition is placed in the foam pump dispenser.

Fig. 1A is a photograph showing the surface of the foamed composition which has been stabilized after the foam has been dispensed, and which has a stabilized foamed composition on the left side and which has not been stabilized on the left side.

Fig. 1B is a photograph showing the surface of the foamed composition which has been stabilized on the right side and the unstabilized foamed composition on the left side after 1 minute of foam distribution.

Figure 1C is a photograph showing the surface of the foamed composition which was stabilized on the right side and the unstabilized foamed composition on the left side after 3 minutes of foam distribution.

Figure 1D is a photograph showing the surface of the foamed composition which has been stabilized on the right side and the unstabilized foamed composition on the left side after 5 minutes of foam distribution.

Fig. 1E is a photograph showing the surface of the foamed composition which had been stabilized on the right side and the unstabilized foamed composition on the left side after 1 hour of foam distribution.

The foamable alcohol-containing composition according to the invention comprises at least one alcohol and at least one foaming surfactant. In one embodiment, the alcohol is a lower alkanol, i.e., an alcohol having from 1 to 4 carbon atoms. These alcohols often have antimicrobial properties. Examples of lower alkanols include, but are not limited to, methanol, ethanol, propanol, isopropanol, butanol, isobutanol, tert-butanol, and mixtures thereof. In one embodiment, the alcohol comprises ethanol.

Generally, the alcohol-containing composition comprises at least about 40 weight percent (wt%) alcohol based on the total weight of the alcohol-containing composition. In one embodiment, the alcohol-containing composition comprises at least about 45 weight percent alcohol, and in another embodiment, the alcohol-containing composition comprises at least about 50 weights The percentage percentage of alcohol, and in yet another embodiment, the alcohol-containing composition comprises at least about 60 weight percent alcohol based on the total weight of the alcohol-containing composition. Some examples may require more or less alcohol, particularly depending on other ingredients and/or amounts used in the composition. In some embodiments, the alcohol-containing composition comprises from about 40 weight percent to about 98 weight percent alcohol, and in other embodiments, the alcohol-containing composition comprises from about 45 weight percent to about 95 weight percent alcohol, yet another In one embodiment, the alcohol-containing composition comprises from about 50 weight percent to about 90 weight percent alcohol, and in still other embodiments, the alcohol-containing composition comprises from about 60 weight percent to about 80 weight percent alcohol. The total weight of the alcohol-containing composition is based on the basis.

The foaming surfactant contributes to the foaming properties of the alcohol-containing composition and may include anionic, cationic, nonionic, zwitterionic or amphoteric surfactants and associated salts thereof. In one embodiment, the lathering surfactant comprises a fluorosurfactant, a siloxane surfactant, or a combination thereof. Fluorosurfactants include compounds containing at least one fluorine atom. Examples of the fluorosurfactant include perfluoroalkylethyl phosphate, perfluoroalkylethylbetaine, fluoroaliphatic amine oxide, sodium fluoroaliphatic succinate, fluoroaliphatic stearate, and fluorine. Aliphatic phosphates, fluoroaliphatic quaternary salts, fluoroaliphatic polyoxyethylenes, and the like, and mixtures thereof.

In one embodiment, the fluorosurfactant contains a charged species, i.e., anionic, cationic or zwitterionic. Fluorosurfactants containing charged species include perfluoroalkylethyl phosphate, perfluoroalkylethylbetaine, fluoroaliphatic amine oxides, sodium fluoroaliphatic succinate, fluoroaliphatic phosphates and fluorine Aliphatic quaternary salt. Specific examples of the fluorosurfactant include DEA-C8-18 perfluoroalkylethyl phosphate, TEA-C8-18 perfluoroalkylethyl phosphate, NH ₄ -C8-18 perfluoroalkylethyl phosphate, and C8- 18 perfluoroalkylethyl betaine.

In one embodiment, the fluorosurfactant comprises a compound [F ₃ CF ₂ C-(CF ₂ CF ₂ ) _x -CH ₂ CH ₂ -OP ₂ O ₃ ] ^- [R ¹ ] which can be represented by the formula ⁺

Wherein [R ¹ ] ⁺ includes DEA, TEA, NH ₄ or betaine, and wherein x is an integer from about 4 to about 18.

The siloxane polymer surfactant is generally characterized by one or more Si-O-Si linkages in the polymer backbone. The oxane polymer surfactant may or may not include a fluorine atom. Therefore, some foaming surfactants are classified into fluorosurfactants and siloxane surfactants. The oxoxane polymer surfactants include organopolyoxyalkylene polydimethyl methoxy olefin polyols, oxime methanol fluids, oxime polyethers, alkyl methyl oxiranes, polydimethyl methoxy oxyalkylamines. (amodimethicone), trioxane ethoxylate, polydimethyl methoxyalkanol, quaternized cerium oxide surfactant, polyfluorene oxide, argon-oxygen cross-linking polymer and fluorinated wax.

Examples of the oxoxane polymer surfactant include polydimethyl methoxy ane PEG-7 undecylenate, PEG-10 polydimethyl methoxy olefin, PEG-8 polydimethyl decane, PEG. -12 polydimethyloxane, perfluorodecylethylcarboxymethyl PEG 10, PEG-20/PPG-23 polydimethyloxane, PEG-11 methyl ether polydimethyloxane, Bi-PEG/PPG-20/20 polydimethyloxane, silicon quats, PEG-9 polydimethyl Oxane, PPG-12 polydimethyloxane, fluoroPEG-8 polydimethyloxane, PEG 23/PPG 6 polydimethyloxane, PEG 20/PPG 23 polydimethylhydrazine Oxyalkane, PEG 17 polydimethyloxane, PEG 5/PPG 3 polymethyl decane, bis-PEG 20 polydimethyl decane, PEG/PPG20/15 polydimethyl siloxane copolymerization Polyol and sulfosuccinate blend, PEG-8 polydimethyloxane\dimer acid blend, PEG-8 polydimethyloxane\fatty acid blend, PEG-8 Polydimethyloxane\cold vegetable oil\polyquaternium blend, random block polymer and mixtures thereof.

In one embodiment, the siloxane polymer surfactant comprises a compound R ² -Si(CH ₃ ) ₂ -[O-Si(CH ₃ ) ₂ ] _a -[O-Si (CH ₃ )R ³ ] _b -O-Si(CH ₃ ) ₂ -R ²

Wherein R ² and R ³ independently include a methyl group or a moiety -(CH ₂ ) ₃ -O-(CH ₂ CH ₂ O) _c -[CH ₂ CH(CH ₃ )O] _d - which may be represented by the formula CH ₂ CH ₂ O) _e H

With the proviso that R ² and R ^{3 are} not simultaneously CH ₃ , wherein a is an integer from about 3 to about 21, b is an integer from about 1 to about 7, c is an integer from about 0 to about 40, and d is from about 0 to An integer of about 40, and e is an integer from about 0 to about 40, with the condition a 3xb and c+d+e 5.

The amount of the foaming surfactant is not particularly limited as long as an effective amount capable of foaming is present. In some embodiments, the effective amount of foaming that can be produced may vary, depending on the amount of alcohol and other ingredients present. In one or more embodiments, the alcohol-containing composition comprises at least about 0.002% by weight of a foaming surfactant based on the total weight of the alcohol-containing composition. In another embodiment, the alcohol-containing composition comprises at least about 0.01% by weight of a foaming surfactant based on the total weight of the alcohol-containing composition. In yet another embodiment, the alcohol-containing composition comprises at least about 0.05% by weight of a foaming surfactant based on the total weight of the alcohol-containing composition.

In one embodiment, the foaming surfactant is present in an amount from about 0.002 weight percent to about 4 weight percent based on the total weight of the alcohol-containing composition. In another embodiment, the foaming surfactant is present in an amount from about 0.01 weight percent to about 2 weight percent based on the total weight of the alcohol-containing composition. It is foreseeable that a larger amount can also effectively produce a foam. All weights of the listed ingredients are based on the active amount and, therefore, do not include the carriers or by-products included in the commercially available materials unless otherwise indicated.

In some specific examples, the amount of fluorosurfactant is ideally limited for economic or other reasons. Advantageously, the stabilized foam can be made from a composition according to the invention containing greater than about 60% by weight alcohol and from about 0.002 to about 0.5% by weight fluorosurfactant, based on the total weight of the composition. In some embodiments, the foamable composition comprises greater than about 65% by weight alcohol and from about 0.002 to about 0.4% by weight fluorosurfactant, based on the total weight of the composition.

In other embodiments, it may be desirable to use larger amounts of lathering surfactant. For example, some of the foamed alcohol-containing compositions of the present invention include specific examples of cleaning or hygiene products that are applied to the surface and then washed away, and larger amounts of foaming surfactants can be used. In these specific examples, the amount of the foaming surfactant is present in an amount of up to about 35% by weight based on the total weight of the composition.

In one or more specific examples, the foaming surfactant is added directly to the alcohol-containing composition. In other embodiments, the foaming surfactant is added to the alcohol-containing composition in the form of a solution or emulsion. In other words, the foaming surfactant can be premixed with the carrier to form a foaming surfactant solution or emulsion, provided that the carrier does not deleteriously affect the foaming properties of the alcohol-containing composition. Examples of the carrier include water, alcohols, glycols such as propylene glycol or ethylene glycol, ketones, linear and/or cyclic hydrocarbons, triglycerides, carbonates, oximes, alkenes, For example, esters such as acetate, benzoates, fatty esters, glycerides, ethers, guanamines, polyethylene glycols, and PEG/PPG copolymers, for example, inorganic salt solutions such as physiological saline. And mixtures thereof. It is to be understood that when the foaming surfactant is premixed to form a foaming surfactant solution or emulsion, the amount of the solution or emulsion added to the alcohol-containing composition may be selected such that the amount of the foaming surfactant falls. Within the above range.

A foaming surfactant solution or emulsion is commercially available, for example, a 14% by weight solution of a fluoroaliphatic phosphate of the registered trademark Masurf ^® FS-115 in water, a fluoroaliphatic phosphate of Masurf ^® FS-130. A 28% by weight solution in water is available from Mason Chemical Company. As is known in the art, oxoxane surfactants are also commercially available.

In some embodiments, the alcohol-containing composition of the present invention further comprises at least one foam stabilizer. In one embodiment, when the foaming surfactant comprises a fluorosurfactant, the foam stabilizer can be selected from polymeric or oligomeric foam stabilizers. In another embodiment, when the foaming surfactant comprises a siloxane surfactant, the foam stabilizer is selective, It may be polymerizable or non-polymerizable. In one embodiment, the foam stabilizer comprises a cationic cationic oligomer or polymer.

Advantageously, comparison of the alcohol-containing compositions of these specific examples with the alcohol-containing compositions that do not contain the foam stabilizer will exhibit improved foam stability. "Foam stability" means the length of time it takes for a bubble to break into a liquid.

Polymeric foam stabilizers include polyquaternium polymers. In general, the polyquaternium polymer is labeled as CTFA. The polyquaternium polymer can be characterized as containing a quaternary ammonium group. Non-limiting examples of polyquaterniums include those listed below in Table 1, including the INCI name and academic name.

In one or more specific examples, the polyquaternium polymer comprises a quaternized copolymer of vinylpyrrolidone and dimethylamino methacrylate, vinylpyrrolidone and dimethylaminopropylmethyl A hydrophobically modified quaternized copolymer of acrylamide, or a mixture thereof.

In one embodiment, the polyquaternium polymer has a molecular weight of from 1,000 to 5,000,000, in another embodiment, from about 1500 to about 2,500,000 and in yet another embodiment, from about 1,000,000 to about 2,000,000.

Other foam stabilizers which are operable to improve foam quality and/or stability include terpolymers of vinyl caprolactam (VCL), vinylpyrrolidone (VP) and dialkylaminoalkyl acrylates, including VP/ Vinyl caprolactam / dimethylaminopropyl methacrylamide copolymer. Yet another foam stabilizer comprises isobutylene/dimethylaminopropyl maleimide/ethoxylated maleimide/maleic acid copolymer. A variety of different foam stabilizers are sometimes referred to as film-forming polymers.

Still other foam stabilizers include acrylamide/ammonium acrylate copolymer, acrylamide/DMAPA acrylate/methoxy PEG methacrylate copolymer, acrylamide/acryloyldimethyl taurate/ Acrylic copolymer, acrylonitrile acrylamidopropyltrimethylammonium/acrylamide copolymer, acrylonitrile acrylamidopropyltrimethylammonium/acrylate copolymer, acrylate/ethyl methacrylate Oxyethyl ester copolymer, acrylate/acrylamide copolymer, acrylate copolymer, acrylate/C1-2 succinate/hydroxy acrylate copolymer, acrylate/ethylamine methacrylate copolymer , acrylate/lauryl acrylate/stearyl acrylate/ethylamine methacrylate copolymer, acrylate/octyl acrylamide copolymer, acrylate/octyl acrylamide/diphenyl Polydimethyl methoxyalkylamine copolymer, acrylate/polytrimethyl methoxy methacrylate copolymer, acrylate/stearyl acrylate/ethylamine methacrylate copolymer, acrylate /Trifluoropropyl methacrylate / polytrimethyl Oxy methacrylate copolymers, acrylate / VA copolymer, acrylates / VP copolymer, adipic acid / diethylenetriamine copolymer, adipic acid / dimethylamino Hydroxypropyldiethylenetriamine copolymer, adipic acid/epoxypropyldiethylenetriamine copolymer, adipic acid/isophthalic acid/neopentyl glycol/trimethylolpropane copolymer, stearic acid Allyl ester / VA copolymer, amine acetyl acrylate / acrylate copolymer, amine ethyl propylene glycol - acrylate / acrylamide copolymer, amine ethyl propylene glycol - AMPD - acrylate / diacetone acrylamide copolymer , ammonium VA / acrylate copolymer, polydimethyl methoxy oxyalkylamine / fluorene heptane copolymer, AMPD - acrylate / diacetone acrylamide copolymer, AMP - acrylate / allyl methacrylate Copolymer, AMP-acrylate/C-18 alkyl acrylate/C1-8 alkyl acrylamide copolymer, AMP-acrylate/diacetone acrylamide copolymer, AMP-acrylate/dimethyl methacrylate Amine ethyl ester copolymer, rod-shaped bacteria / rice bran extract / soybean extract fermentation filtrate, behenyl methacrylate / ethylene oxide methacrylate copolymer, bis-butoxy polydimethyl decane Amine/PEG-60 copolymer, bis-isobutyl PEG-14/polydimethyloxyalkylamine copolymer, bis-isobutyl PEG-15/polydimethyl Oxyalkylamine copolymer, butyl acrylate/ethylhexyl methacrylate copolymer, butyl acrylate/hydroxypropyl polydimethyloxy oxyalkylamine acrylate copolymer, butyl acrylate/MA copolymer, PVM Butyl ester/MA copolymer, calcium/sodium PVM/MA copolymer, chitosan sugar, chitosan lactic acid ester, corn starch/acrylamide/sodium acrylate copolymer, dehydrogenated xanthan gum, diethyl Diolamine, epichlorohydrin/hexahydropyrazine copolymer, polydimethyloxane cross-linked copolymer, polydimethyl methoxy oxane/co-semi-oxyalkylene copolymer, diphenyl polydimethyl Oxyalkyleneamine, ethyl acetate/MA copolymer of PVM, ethyltrimethylammonium methacrylate/hydroxyethyl acrylamide copolymer, hydrolyzed wheat protein/PVP crosspolymer, hydroxypropyl poly Methyl methoxyalkyl Acrylate copolymer, hydroxypropyltrimethylammonium hydrolyzed corn starch, isobutylene/ethyl maleimide/hydroxyethyl maleimide copolymer, isobutylene/MA copolymer, methyl Isobutyl acrylate/trifluoroethyl methacrylate/bis-hydroxypropyl polydimethyl decane acrylate copolymer, isopropyl ester/MA copolymer of PVM, lauryl acrylate crosspolymer, Lauryl alkyl methacrylate/ethylene glycol dimethacrylate crosspolymer, lauryl PEG-9 polydimethyl oxirane polydimethyl oxane, methacrylic acid / acrylamide Sodium methylpropane sulfonate copolymer, methacryl decyl ethyl betaine/acrylate copolymer, methoxy polydimethyl methoxy oxyalkylamine / fluorene copolymer, methoxy PEG-114 /polyε-caprolactone, myristic acid/palmitic acid/stearic acid/capric acid/eicosan diglyceride, octyl acrylamide/acrylate/butyl methacrylate copolymer , PEG-800/polyvinyl alcohol copolymer, PEG/PPG-25/25 polydimethyloxy oxyalkylamine/acrylate copolymer, PEG-8/SMDI copolymer, polypropylene decylamine, polypropylene Ester-6, polyacrylate-8, polyacrylate-9, polyacrylate-15, polyacrylate-16, polyacrylate-17, polyacrylate-18, polyacrylate-19, poly-β-aniline /glutaric acid crosslinked polymer, polybutylene terephthalate, polyester-1, polyethyl acrylate, polyethylene terephthalate, polyimide-1, polymethacryl fluorenyl Ethyl betaine, polypentaerythritol terephthalate, polyperfluoroperhydrophenanthrene, polyquaternium-4/hydroxypropyl starch copolymer, polyurethane-1, polyurethane -6, Polycarbamate-10, Polyurethane-18, Polyurethane-19, Polyvinyl Acetate, Polyvinyl Butyral, Polyvinylcaprolamine, Poly Vinyl methamine, polyvinylimidazolium acetate, polyvinyl methyl ether, PVM Butyl ester potassium salt/MA copolymer, PVM ethyl ester potassium salt/MA copolymer, PPG-70 polyglyceryl-10 ether, PPG-12/SMDI copolymer, PPG-51/SMDI copolymer, PVM/ MA copolymer, PVP/VA/itaconic acid copolymer, PVP/VA/vinyl propionate copolymer, rhizobial gum, rosin acrylate, shellac, decyl quaternary ammonium-16/glycidoxy dimethyl methacrylate Cross-linked oxyalkylene polymer, butyl acrylate sodium salt/MA copolymer of PVM, ethyl ester sodium salt/MA copolymer of PVM, sodium polyacrylate, sodium poly-γ-aminoglutarate, soybean protein Acid ester, sterculia urens gum, terephthalic acid/isophthalic acid/sodium isophthalate/ethylene glycol copolymer, dimethylolpropane triacrylate, trimethyl oxime Based on alkylaminopyristyl pullulan, VA/crotonate copolymer, VA/crotonate/methacryloxybenzophenone-1 copolymer, VA/crotonate/ Neodecanoic acid vinyl ester copolymer, VA/crotonate/vinyl propionate copolymer, VA/DBM copolymer, VA/vinyl benzoate/crotonate copolymer, vinylamine/vinyl alcohol copolymer, Vinyl caprolactam / VP / A Dimethylamine ethyl acrylate copolymer, VP/acrylate/lauryl methacrylate copolymer, VP/dimethylaminoethyl methacrylate copolymer, VP/DMAPA acrylate copolymer, VP/ Hexadecene copolymer, VP/methacrylamide/vinylimidazole copolymer, VP/VA copolymer, VP/vinyl caprolactam/DMAPA acrylate copolymer, yeast palmitate, such as phenylpropyl a ruthenium-based polymer or resin such as dimethyl methoxy phthalate, trimethyl decyl decanoate, cyclopentaoxane, trimethyl decyl phthalate, diisostearyl Mercapto trimethylolpropane decyloxydecanoate, vinyl polydimethyloxane crosspolymer/blend and alkyl cetyl alkyl poly Methyl decane cross-linking polymer.

In one embodiment, the foam stabilizer comprises a VP/ethylene caprolactam/dimethylaminopropyl methacrylamide copolymer sold under the registered name Aquaflex SF-40 or under the registered name Aquaflex XL-30 Isobutylene/dimethylaminopropyl maleimide/ethoxylated maleimide/maleic acid copolymer sold.

In one embodiment, the foam stabilizer is present in an amount from about 0.005 to about 4 weight percent active, based on the total weight of the alcohol-containing composition. In another embodiment, the foam stabilizer is present in an amount from about 0.01 to about 1 weight percent active, based on the total weight of the alcohol-containing composition, and in yet another embodiment, the foam stabilizer It is present in an amount of from about 0.02 to about 0.2 weight percent active, based on the total weight of the alcohol-containing composition.

In one embodiment, the foam stabilizer is added directly to the alcohol-containing composition. In one or more specific examples, the foam stabilizer is added to the alcohol-containing composition in the form of a solution or emulsion. In other words, the foam stabilizer can be premixed with the carrier to form a foam stabilizer solution or emulsion, with the proviso that the carrier does not adversely affect the properties of the alcohol-containing composition. Examples of the carrier include water, alcohols, glycols such as propylene glycol or ethylene glycol, ketones, linear and/or cyclic hydrocarbons, triglycerides, carbonates, oximes, alkenes, For example, esters such as acetate, benzoates, fatty esters, glycerides, ethers, guanamines, polyethylene glycols, and PEG/PPG copolymers, for example, inorganic salt solutions such as physiological saline. And mixtures thereof. It is to be understood that when the foam stabilizer is premixed to form a foam stabilizer solution or milk In the case of a liquid, the amount of the solution or emulsion added to the alcohol-containing composition is selected such that the amount of the foam stabilizer falls within the above range.

In one embodiment, the weight ratio of foaming surfactant to foam stabilizer is from about 3.5:1 to about 14.5:1, and in another embodiment, the weight ratio of foaming surfactant to foam stabilizer is About 8:1 to about 11:1.

In some embodiments, the foam stabilizer will increase foam stability, i.e., the length of time it takes for the foam to break into liquid. In particular, it has been found that when the foaming surfactant comprises a fluorosurfactant, the presence of the foam stabilizer will improve the stability of the foam. When the foaming surfactant comprises a siloxane polymer, the foam stabilizer is selective.

The foam stabilizer can be manipulated in a number of ways to improve the stability of the foam. In one or more embodiments, the foam stabilizer will also improve the quality of the foam, i.e., increase the number of bubbles and/or reduce the size of the bubbles.

Referring now to the drawings, Figure 1A shows a photograph of the surface of the foamed composition that has been stabilized after the foam has been dispensed, with the stabilized foamed composition on the right side and the unstabilized foamed composition on the left side. More specifically, the two foaming compositions contain the same amount of ethanol, fluorosurfactant, humectant, and water. The foamed composition on the right also contained about 0.14% by weight of a foam stabilizer. It can be seen that the unstabilized foam contains some small bubbles, but contains a large amount of loose foam than the stabilized foam.

Fig. 1B is a photograph showing the surface of the foamed composition of Fig. 1A after 1 minute of foam distribution. It can be seen that although the stabilized foam remains substantially unchanged, the unstabilized foam will become wet around the edges.

Fig. 1C is a photograph showing the surface of the foamed composition of Fig. 1A after 3 minutes of foam distribution. It can be seen that the stabilized foam remains substantially unchanged, however the unstabilized foam becomes very wet.

Fig. 1D is a photograph showing the surface of the foamed composition of Fig. 1A after 5 minutes of foam distribution. It can be seen that the stabilized foam remains substantially unchanged, however, the unstabilized foam is mainly liquid, leaving only a few bubbles.

Fig. 1E is a photograph showing the surface of the foamed composition of Fig. 1A after 1 hour of foam distribution. It can be seen that the stabilized foam has a lot of foam, but the unstabilized foam collapses into a liquid state. In one embodiment, when the composition containing more than 40% by weight of an alcohol, a fluorosurfactant, and a foam stabilizer is passed through a non-liquefied gas foaming pump at room temperature, the foam stability is greater than that of a foam stabilizer not included. The foam stability produced by the composition when it is passed through a non-liquefied gas foaming pump.

In one embodiment, when the foamable alcohol-containing composition of the present invention is passed through a non-liquefied gas foaming pump at room temperature, the foam stability is at least about 30 seconds, and in another embodiment at least about For 3 minutes, or in other words, the alcohol-containing composition maintains its foam form and does not break into a liquid state for at least 3 minutes. In another embodiment, the foam stability is at least about 5 minutes, and in yet another embodiment, the foam stability is at least about 15 minutes. In one or more specific examples, the foam stability is at least about 30 minutes, and in yet another embodiment, the foam stability is at least about 60 minutes.

The alcohol-containing composition of the present invention may further comprise a wide range of selectivities The ingredients, with the proviso that they do not adversely affect the foam formability of the alcohol-containing composition, or the foam stability. CTFA International Cosmetic Ingredient Dictionary and Reference, 11th Edition, 2005, and 2004 CTFA International Procurement Guidelines, both of which are incorporated by reference in their entirety, describing various unrestricted uses in the skin care industry. Cosmetics and pharmaceutical ingredients, all of which are suitable for use in the compositions of the present invention. Non-limiting examples of functional classification of the described components are included in these reference examples. Examples of these functional classifications include: abrasives, anti-acne agents, anti-caking agents, antioxidants, binders, biological additives, leavening agents, chelating agents, chemical additives, colorants, cosmetic astringents, cosmetic products Biocides, denaturants, drug astringents, emulsifiers, topical analgesics, film formers, perfume ingredients, moisturizers, sunscreens, plasticizers, preservatives, propellants, reducing agents, skin bleaches, emollients Agent (softener, moisturizer, mixed and non-occlusive), skin care agent, solvent, foam booster, hydrotrope, solubilizer, suspending agent (non-surfactant), sunscreen, UV absorber, anti-adhesive Agents and tackifiers (aqueous and non-aqueous). Examples of other material functional classifications well known to those skilled in the art that are useful herein include solubilizers, release agents, and keratolytic agents. In one embodiment, the alcohol-containing composition further comprises glycerin.

A co-surfactant may be included in the alcohol-containing composition for the purpose of increasing or changing the quality and characteristics of the foam, changing the texture of the final formulation upon wiping and/or drying, providing sustained or long-acting microbial action of the alcohol, dissolving, for example, flavors Or other ingredients such as sunscreens, and to ease the irritation. Co-surfactants include, but are not necessarily limited to, thiosuccinate, amine oxide, PEG-80 sorbitol laurate, polyglucoside, alkanolamine, sorbitol derivatives, Fatty alcohol ethoxylates, quaternary ammonium compounds, guanamine amines, sulfobetaines, isothiohydroxy acids, sarcosine, betaines and fatty alcohol polyethylene glycols.

Although propellants can be used to create a stable foam, propellants are not necessarily required. In some embodiments, the amount of propellant is less than about 1000 parts per million by weight based on the total weight of the alcohol-containing composition. In one embodiment, the alcohol-containing composition is substantially free of propellant, such as a hydrocarbon propellant. Substantially free means that the propellant dose in the alcohol-containing composition is less than about 100 parts per million by weight based on the total weight of the alcohol-containing composition.

In one embodiment, the alcohol is added to the sole active antimicrobial component of the composition, and in this particular embodiment the auxiliary antimicrobial component is less than about 0.1 weight percent based on the total weight of the alcohol-containing composition. In other embodiments, the composition includes an auxiliary antimicrobial agent in addition to the alcohol. Auxiliary antimicrobial agents include, but are not limited to, triclosan (Triclosan), also known as 5-chloro-2- (2,4-dichlorophenoxy) phenol and may be registered name IRGASAN ^® from Ciba-Geigy Co. Chloroxylenol, also known as 4-chloro-3,5-dimethylphenol, is available under the registered name NIPACIDE® MX or PX from Nipa Laboratories, Inc.; hexetidine, also Known as 5-amino-1,3-bis(2-ethylhexyl)-5-methylhexahydropyrimidine; chlorhexidine salt, including chlorhexidine gluconate and N,N"-double (4-chlorophenyl)-3,12-diimido-2,4,11,14-tetraazatetradecanediimine decylamine; 2-bromo-2-nitropropane-1; 3-di Alcohol, benzalkonium chloride; cetylpyridinium chloride; alkyl dimethyl benzyl ammonium chloride; iodine; phenol derivative, pyrrolidone iodine including polyvinylpyrrolidone iodine; p-hydroxybenzoic acid Ester; carbendazim and its derivatives, including derivatives of 2,4-imidazolidinone and 2,4-imidazolidinone and dimethylol-5,5-dimethylhydantoin ( Also known as DMDM intramethylene urea or a synergistic broad-spectrum preservative (glydant); phenoxyethanol; Of 1- (3-chloroallyl) -3,5,6-triaza-l-azoniaadamantane cis isomer, also known as quaternium-15 and the registered name DOWCIL ^TM 2000 Available from Dow Chemical; diazolidinium imidazolium, benzethonium chloride; methylammonium chloride, and mixtures thereof. When used, the co-improving agent is present at about 0.1 to An amount of about 1% by weight based on the total weight of the alcohol-containing composition.

The alcohol-containing composition of the present invention may further comprise various different topical pharmaceutically active ingredients as needed, provided that they do not adversely affect the foam forming properties of the alcohol-containing composition, or foam stability. Examples of topical pharmaceutically active ingredients include salicylic acid, acetylsalicylic acid, cis-vitaminic acid, trans-vitaminic acid, N-ethyl decyl-L-photocysteine, lipoic acid, azelaic acid, phytic acid , lisophosphotidic acid, tetracycline, ibuprofen, naproxen, acetominophen, hydrocortisone, resorcinol, benzene Oxyethanol, phenoxypropanol, phenoxyisopropanol, 2,4,4'-dichloro-2'-hydroxydiphenyl ether, 3,4,4'-trichloro symmetrical diphenylurea, Octopyrox, 2-phenylbenzimidazole-5-sulfonic acid, dihydroxyacetone, benzammonium peroxide, 2,4,4'-trichloro-2-hydroxydiphenyl ether, phenoxy Ethanol, phenoxypropanol, phenoxy Isopropanol, phytic acid, lipoic acid, lysophosphatidic acid, benoxaprofen, flurbiprofen, fenoprofen, fenbufen, ketopro Ketoprofen, indoprofen, priprofen, caroffen, oxaprozin, pranoprofen, miroprofen, Tioxaprofen, suprofen, alminoprofen, tiaprofenic acid, fluprofen, bucloxic acid, benzocaine ( Benzocaine), lidocaine, bupivacaine, chloroprocaine, dibucaine, etidocaine, mepivacaine , tetracaine, dyclonine, hexylcaine, procaine, cocaine, ketamine, pramocaine Pramoxine), phenol, dihydroxyacetone, tyrosine, tyrosine ethyl ester, phosphorus-DOPA, β-indoline drug, quinoline drug, ciprofloxacin , nrofloxacin, erythromycin, amikacin, doxycycline, capreomycin, chlorhexidine, chlortetracycline (chlortetracycline), oxytetracycline, clindamycin, ethambutol, hexamidinee isethionate, metronidazole (metronidazole), pentamidine, gentamicin, kanamycin, lineomycin, methacycline, hexamethylenetetramine ( Methenamine), minocycine, neomycin, netilmicin, paromomycin, streptomycin, tobramycin , miconazole, tetracycline hydrochloride, erythromycin, erythromycin, erythromycin estolate, erythromycin stearate, amikacin sulfate, deoxytetracycline hydrochloride , capreomycin sulfate, chlorhexidine glucuronide, chlorhexidine hydrochloride, chlortetracycline hydrochloride, oxytetracycline hydrochloride, clindamycin hydrochloride, ethambutol hydrochloride, metronidazole hydrochloride, pentamidine hydrochloride, Gentamicin sulfate, kanamycin sulfate, lincomycin hydrochloride, methotrexate hydrochloride, methenamine hippurate, methotamine mandelate, hydrochloric acid rice Nincycline hydrochloride, neomycin sulfate, ethyl cilostatin sulfate, sulfur Mycomycin, streptomycin sulfate, tobramycin sulfate, miconazole hydrochloride, amanfadine hydrochloride, omanvadine sulfate, pyridoneethanolamine, p-dichloro-xylenol, nystatin (nystatin), tolnaftate, clumprimazole, p-methoxycinnamic acid 2-ethylhexyl ester, p-aminobenzoic acid ester, p-aminobenzoic acid, 2 -Phenylbenzimidazole-5-sulfonic acid, octocrylene, 2-hydroxy-4-methoxy-benzophenone, valproate salicylate, octyl salicylate, 4 , 4'-methoxy -T-butyldibenylmethane, 4-isopropyldibenylmethane, 3-phenylene fluorenone, 3-(4-methylphenylene)fluorenone, titanium dioxide, oxidation 4-N,N-(2-ethylhexyl)methylamine benzoate of hydrazine, iron oxide, 2,4-dihydroxybenzophenone, 4-N containing 4-hydroxybenzhydrylmethane , N-(2-ethylhexyl)methylamine benzoate, 4-N,N-(2-ethylhexyl)methyl 2-hydroxy-4-(2-hydroxyethoxy)benzophenone 4-N,N-(2-ethylhexyl)methylamine benzoate, tetracycline, isobutylbenzene, 4-aminocarbonyl benzoate, 4-(2-hydroxyethoxy)dibenzoylmethane Acetic acid, acesulfame, p-acetaminophen, resorcinol, 3,4,4'-trichloro symmetrical diphenylurea, pyridoneethanolamine, pharmaceutically acceptable salts and mixtures thereof.

In one embodiment, the balance of the alcohol-containing composition includes water or other suitable solvent. In one embodiment, the formulation includes one or more volatile oxygen-based materials to further assist in the evaporation process. Exemplary volatile helium oxygen has a lower heat of vaporization than alcohol. In one embodiment, the use of a helium oxygen-based material reduces the surface tension of the flowing composition. In one embodiment, the formulation may include from about 4% to about 50% by weight of a concentration of the oxygen-based material, such as cyclomethoxane, trimethyldecyloxydecanoate, or combinations thereof, and In another embodiment, from about 5% by weight to about 35% by weight, based on the total weight of the alcohol-containing composition.

In one embodiment, such as the rinse formulation described above, the balance of the alcohol-containing composition includes a lathering surfactant.

The alcohol-containing composition can be prepared by simply mixing the ingredients together. The order of addition is not particularly limited. In one embodiment, the skin-disinfecting alcohol-containing composition is slowed by comprising slowly dispersing the foaming surfactant in the alcohol. And agitating, adding water, then adding a foam stabilizer, and mixing until the mixture is homogeneous.

The foamable composition of the present invention can be utilized in any type of disperser commonly used in foam products. Advantageously, the aerosolized product does not require foaming, although the foamable composition can be foamed by atomizing the composition as desired. A disperser that can mix the foamable alcohol-containing composition with air or a passive gas can be used. A passive gas includes a gas that does not substantially react or adversely affect the foamable composition. Examples of the passive gas include nitrogen, argon, helium, neon, krypton, xenon, and krypton. In one embodiment, the alcohol-containing composition is used in a disperser using a foaming pump that combines ambient air or a passive gas and an alcohol-containing composition in a mixing chamber and passes the mixture through a screen. In various embodiments, the composition has a viscosity of less than about 100 millipascals, in one embodiment less than about 50 millipascals, and in another embodiment less than about 25 millipascals.

The alcohol-containing composition of the present invention will produce a stabilized foam. As a result, the foamed composition does not break into a liquid state and drip from the foaming pump and/or the associated disperser element.

Accordingly, the present invention further provides a method of reducing the dripping of a composition from a foaming pump. When the foamable composition is dispersed by using a foamable pump, a portion of the dispersed composition, now in the form of a foam, will remain in the head of the disperser until another portion is dispersed. If the foam in the head of the disperser will break into a liquid state between the use of the disperser, the liquid will drip from the head of the dispenser. The time between use of the dispenser can generally be indicated as X minutes. "X" can vary widely.

Advantageously, the stabilized foam of the present invention does not drip from the dispenser when X is about 3 minutes or less. In one embodiment, the stabilized foam does not drip from the dispenser when X is about 5 minutes or less, and in another embodiment, X is about 15 minutes or less. In one or more specific examples, the stabilized foam does not drip from the dispenser when X is about 30 minutes or less, and in other embodiments, when X is about 60 minutes or less. The stabilized foam does not drip from the dispenser.

In order to illustrate the embodiments of the present invention, they were prepared and tested in the following examples. However, the examples should not be construed as limiting the scope of the invention. The scope of these patent applications will be used to define the invention.

Example

Example 1 was prepared by slowly dispersing a fluorosurfactant, DEA-C8-18 perfluoroalkyl ether phosphate, in ethanol to moderate agitation until uniform dispersion was achieved. Next, a humectant is added and mixed until the mixture is homogeneous. Mix with water and add water. The solution was agitated until a homogeneous mixture was reached.

The foamable mixture was passed through an Airspray® foam pump. The quality and stability of the foam were improved in the manner described below and the results are summarized in Table 2.

A simple 1 to 5 system was used to evaluate the foam of each system, while 5 was the best.

Foam quality rating series: The quality is the measure of the appearance of the dispersed foam as it is dispersed by a typical commercial foam pump.

Series 0 to 5

0 no foam

1 wet and wet foam with large and loose bubbles

2 large and loose bubbles, some small bubbles

3 foam is about the same amount of small and large bubbles

4 foam mainly has small and dense bubbles

5 a soft and dense foam with small, dense bubbles

Foam Stability Rating Series: The stability is assessed by measuring the time it takes for the foam to break into liquid. The poor stability score is related to dripping from the diffuser on the wall countertop. A score of 3 or higher indicates that the stability of the alcohol foam is quite good.

Series 0 to 5

0 melt immediately (<30 seconds)

1 about 30 to 60 seconds to melt

2 about 1 to 15 minutes of melting

3 about 15 to 30 minutes to melt

4 about 30 to 60 minutes to melt

5 after about 60 minutes, the bubble is still

Example 2 was prepared as described in Example 1, except that Polyquaternium-11 was added after water. The foaming mixture was passed through a foaming pump and evaluated in the manner of Example 1. The results are summarized in Table 2. The wording "qs" means adding up to a total of 100 percentage points.

Examples 3 to 7 were prepared, foamed and evaluated in the manner described in Examples 1 and 2 except that the amounts were varied as shown in Table 2.

Examples 8 to 11 were prepared in the manner described in Example 2 except that in Examples 8, 9, and 11, the polyquaternium-11 was replaced by another polymer. Each foamable mixture was passed through a foaming pump and evaluated in the manner of Example 1. The results are summarized in Table 3.

Examples 12 to 24 were prepared in the manner described in Example 1, except that the amount of the fluorosurfactant was varied, and the fluorosurfactant of Example 1 was used instead of or in place of the two surfactants, perfluorodecyl B. Base carboxy fluorenyl PEG 10 dimethyl methoxy oxane and dimethyl methoxy olefin copolymer undecylenate. Example 10 also contained polyquaternium-11. Each foamable mixture was passed through a foaming pump and evaluated in the manner of Example 1. The results are summarized in Tables 4 and 5.

Examples 25 to 36 were prepared in the manner described in Example 2 except that the amounts were varied as shown in Tables 6 and 7, and in one embodiment, the fluorosurfactant was used in addition to or in place of Example 2 using different foamed surfaces. Active agent. Example 33 contained no polyquaternium-11. The results are summarized in Tables 6 and 7.

The embodiments of the foamable composition of Example 1 was placed in a wall dispenser Airspray ^® foaming pump. A composition is dispensed from the pump. After 3 () seconds to 1 minute, the liquid was seen to drip from the dispenser head.

To the foamable composition of Example 1, 0.1% by weight of polyquaternium-11 was added. Airspray ^® foam pump of this composition was placed in a wall dispenser. A composition is dispensed from the pump. During the next 10 minutes, no dripping was seen.

Different modifications and variations will be apparent to those skilled in the art without departing from the scope of the invention. The invention is of course not limited to the illustrative embodiments described herein.

Claims (9)

A foamable alcohol-containing composition comprising: at least about 40 weight percent alcohol, based on the total weight of the alcohol-containing composition; and from about 0.002 to about 4 weight percent selected from the group consisting of oxygen The foaming surfactant of the alkane polymeric surfactant, based on the total weight of the alcohol-containing composition, wherein the foamable alcohol-containing composition has a viscosity of less than about 100 mPas. The composition of claim 1, wherein the foamable composition has a viscosity of less than about 50 mPas. The composition of claim 1, wherein the foaming surfactant comprises a siloxane polymer surfactant: R ² -Si(CH ₃ ) ₂ -[O-Si(CH) ₃ ) ₂ ] _a -[O-Si(CH ₃ )R ³ ] _b -O-Si(CH ₃ ) ₂ -R ² wherein R ² and R ³ independently include a methyl group or a moiety which can be represented by the following formula -(CH ₂ ) ₃ -O-(CH ₂ CH ₂ O) _c -[CH ₂ CH(CH ₃ )O] _d -(CH ₂ CH ₂ O) _e H with the condition that R ² and R ^{3 are} different CH ₃ , wherein a is an integer from about 3 to about 21, b is an integer from about 1 to about 7, c is an integer from about 0 to about 40, d is an integer from about 0 to about 40, and e is from about 0 to An integer of about 40, with the condition a 3xb and c+d+e 5. The composition of claim 1, wherein the siloxane polymer surfactant comprises one selected from the group consisting of an organic polyoxyalkylene polydimethyl siloxane polyol, a hydrazine methanol fluid, a decyl polyether, Alkylmethyl oxirane, amodimethicone, trioxane B A surfactant of an oxylate, a polydimethyl methoxyalkanol, a quaternized cerium oxide surfactant, a polyoxynium oxide, a cerium oxygen crosslinking polymer, a cerium oxide wax, and a mixture thereof. The composition of claim 1, wherein the alkoxyalkyl polymer surfactant comprises polydimethyloxane PEG-7 undecylate, PEG-10 polydimethyloxane, PEG -8-polydimethyloxane, PEG-12 polydimethyloxane, perfluorodecylethylcarboxymethyl PEG 10, PEG-20/PPG-23 polydimethyloxane, PEG- 11 methyl ether polydimethyl siloxane, bis-PEG/PPG-20/20 polydimethyl methoxy oxane, silicon quats, PEG-9 polydimethyl siloxane, PPG- 12-polydimethyloxane, fluoroPEG-8 polydimethyloxane, PEG 23/PPG 6-polydimethyloxane, PEG 20/PPG 23-polydimethyloxane, PEG 17-polymer Dimethyl decane, PEG 5/PPG 3 polymethyl decane, bis-PEG 20 polydimethyl decane, PEG/PPG20/15 polydimethyl decane copolyol and sulfobutyl Diester blends, or mixtures thereof. The composition of claim 1, wherein the composition further comprises a foam stabilizer comprising quaternary ammonium of polyquaternium, vinylpyrrolidone and dimethylamino methacrylate Hydrophobically modified quaternized copolymers of copolymers, vinylpyrrolidone and dimethylaminopropylmethacrylamide, or mixtures thereof. The composition of claim 1, wherein the composition further comprises a foam stabilizer, which comprises vinyl caprolactam (VCL), vinyl pyrrolidone (VP), and dialkylaminoalkyl acrylate. Ester terpolymer, or isobutylene / dimethylaminopropyl maleimide / ethoxylated maleimide / maleic acid copolymer. The composition of claim 1, wherein the foaming surfactant comprises PEG-10 polydimethyloxane, and wherein the composition further comprises a polyquaternium 11. A method of reducing the dripping of a composition from a foam pump dispenser suitable for dispensing the composition, the method comprising: providing a foamable composition comprising: at least about 40 weight percent alcohol, the weight percentage being Based on the total weight of the alcohol-containing composition; and a foaming surfactant selected from the group consisting of a siloxane polymer surfactant; providing a foaming pump dispenser having a dispensing head; placing the foamable composition And a foamable composition, wherein the foamable composition has a viscosity of less than about 100 mPas, wherein a portion of the portion remains in the dispensing head at least about 3 minutes, and the portion remaining in the dispenser does not drip from the dispenser.