TW201231027A - Intraocular lens transfer case - Google Patents

Abstract

An intraocular lens (IOL) transfer case for transferring an IOL to an injection cartridge includes a lens holder for holding the IOL. The lens holder includes a bore. Folding members within the lens holder are configured to fold the IOL into a partially folded position when the IOL is slid through the bore across the folding members. The IOL transfer case also includes an interface configured to removably connect to an injection cartridge. The interface is positioned to deliver the IOL in the partially folded position within the injection cartridge when the interface is connected to the injection cartridge. The IOL transfer case also includes a plunger connected to the lens holder and configured to push the IOL in the partially folded position through the bore to deliver the IOL into the injection cartridge.

Description

201231027 VI. Description of the invention: [Rhyme ^ Ming hu zhi _ control _ winter good mussels: Wei] Related application This application claims to be filed on December 20, 2010, US temporary application number 61/424,883 Priority, the content of which is incorporated herein by reference. FIELD OF THE INVENTION This invention relates to intraocular crystals (I 〇 Ls) and more particularly to an I 〇 L delivery cartridge for loading an IOL into a cartridge. C prior art; 3 BACKGROUND OF THE INVENTION The human eye acts in its simplest manner to provide vision by transmitting and refracting light through a transparent outer portion called a cornea, and further via a crystal lens (lens) ) Focus the image on the retina behind the eye. The quality of the focused image depends on a number of factors, including the size, shape and length of the eye, and the shape and transparency of the cornea and the lens. When the damage, age or disease causes the crystal to become less opaque, the vision degrades as the light that can be transmitted to the retina decreases. This defect in the crystal of the eye is medically known as a cataract. The treatment for this condition is surgical removal of the crystals and implantation of an artificial lens or IOL. Although the early IOLs were made of hard plastics [such as polymethylmethacrylate (PMMA)], from polysilicon, soft acrylics and hydrogels 3 201231027 Soft, collapsible IOLs made by (hydrogels) have gradually become popular because they can be folded or rolled and inserted through a small incision. Several methods of rolling or folding a crystal are used. A popular method is an injector cartridge that folds the crystal and provides a relatively small diameter lumen through which the crystal can be pushed into the eye, usually by A soft-tip plunger [such as one described in U.S. Patent No. 4,681,102 (8 & Bo 11), which includes a pair of open, longitudinal hinges]. A similar design is exemplified in U.S. Patent Nos. 5,494,484 and 5,499,987 (Feingold) and 5,616,148 and 5,620,450 (Eagles et al.). Other designs include, for example, U.S. Patent No. 5,275,604 (Rheinish et al.) and U.S. Patent No. 5,653,715 (Reich et al.). In these prior art systems, an IOL is provided in a crystal cell that is transported to an injector (e.g., by using a recording). However, the step of transporting the crystal crystal from the cartridge to the injector 可 may inadvertently cause damage to the 'Xuan I0L' because the lens body (〇ptic) of the I0L is caught by the awl or the haptics from the box. The I0L is torn off. An alternative method is to provide a preloaded injector [such as described in U.S. Patent No. 7,156,854 (Brown et al.)]. In this example, there is no separate loading step. However, this combined injector system is completely disposable and is incompatible with reusable handpieces. Yet another option is a preloaded crystal transport cassette that uses a mechanism to transport the unit to a craftsman. But in order to maintain the crystal in the correct loading position and to ensure that the I〇L is correctly lost

S 4 201231027 To this raft, the existing crystal transport cassette involves a relatively complex mechanical conveyor. SUMMARY OF THE INVENTION In a particular embodiment of the invention, an intraocular lens (IOL) delivery cassette for delivering an IOL to an infusion cassette includes a crystal holder for receiving the IOL. The crystal holder includes a hole. The folding elements in the crystal holder are assembled to fold the IOL into a partially folded state as the IOL is slid through the apertures through the folding elements. The IOL transport case also includes an interface that is configured to be movably coupled to an injection port. When the interface is connected to the injection port, the interface is placed to deliver the IOL in a partially folded state into the injection port. The IOL delivery cartridge also includes a plunger that is coupled to the crystal holder and that is configured to urge the partially collapsed IOL through the aperture to deliver the IOL to the plunger. In another embodiment of the present invention, a method of transporting an IOL to a helium from a monolithic transport cassette includes providing a crystal holder, a hole in the crystal holder, and a folding member in the hole ( A crystal delivery cassette that assembles the IOL into a partially folded state when the IOL is slid through the folding elements. The method further includes movably connecting an injection cassette to the crystal delivery cassette, releasing the IOL from a resting state in the crystal delivery cassette, sliding the IOL through the folding elements to fold the IOL into a portion In the folded state, the IOL in the partially folded state is pushed through a distal end of the hole into the injection port to 201231027 and the crystal delivery cassette and the injection port are separated. Other features of the present invention will become apparent from the following description of the drawings. BRIEF DESCRIPTION OF THE DRAWINGS FIGS. 1A and 1B illustrate an intraocular lens transfer case according to a particular embodiment of the present invention; and FIG. 2 shows an alternative crystal delivery case according to another embodiment of the present invention; 3 is a top level assembly view of a crystal transport case in accordance with a particular embodiment of the present invention; and FIG. 4 is a view showing a transfer from a crystal transport cassette to an infusion. A flow chart of an example method. DETAILED DESCRIPTION OF THE INVENTION Sections 1A and 1B illustrate an item and cross-sectional view of an intraocular lens delivery cartridge 100 in accordance with a particular embodiment of the present invention. The delivery system 1() includes a crystal holder 1 () 2 having a hole 1 () 4 and a plunger 106. The crystal holder 1〇2 can be any component (p0rti〇n), component (comp0nents) or assembly (collection 〇fc〇mp〇nents) that accommodates an intraocular lens (IOL) 200 for transport [excluding] A nozzle portion for injecting the IOL 200 through the mouth (incisi〇n). The term "plunger" refers to any component that is advanced through the bore 4 to push an intraocular lens through the 'injector body', which may, but need not, be coupled to the intraocular lens transfer case 100. Other components. In a special case, all crystals

S 6 201231027 The transport cartridge 100 can be formed as a single piece from a suitable material [which can include, for example, polypropylene or polyethylene]. Various embodiments may also include a lubricious coating within the aperture 1〇4 of the injector body 1〇2 to facilitate advancement of the intraocular lens. In order to facilitate the movement of the I through the transport container 100, the crystal transport cassette 1 can also be filled with a viscoelastic material or a liquid such as a balanced saline solution. Various embodiments of the inventive crystal transport cassette 1A provide an improved method and system for transporting an I 〇 L 2 〇〇 from the crystal transport cassette to an enthalpy for injection. Such specific examples may advantageously allow for the use of current crucibles and reusable handpieces while simultaneously operating the crystals with forceps during the transport of the crystals. This shift reduces the likelihood of crystal damage and provides a more controlled delivery process. However, unlike the previous crystal transport cassette, a different specific example of the invention of the crystal transport cassette 1 藉 by sliding the I0L 200 and dropping the I 〇 L 200 in the hole is not only injected at a hai 〇 L During the operation of the program, and during the transport of the IOL 200 from the crystal transport cassette 100 to the crucible. In some embodiments, the familiarity of the plunger-and-hole system can then be leveraged in the crystallisation delivery operation, but it can also incorporate the advantages of a preloaded crystal delivery cartridge (previously not It has been appreciated that the combination 匣 with the handpiece system provides a complete and continuous folding operation through the hole). Counter-intuitive separation of the plunger_and_hole operation into two separate steps (a delivery step and a loading step), thus allowing both a preloaded crystal delivery cassette and a reusable handpiece to be effective The advantages achieved by the land. 201231027 4I0L 200 can be in the form of any intraocular lens of a nexibie material, including but not limited to hydrogels, silicone or acrylic mateHas [such as A crucible acrylic material (known as the trademark AcrySof®) is described in U.S. Patent No. 5,290,892. The i〇L 200 includes at least one optic 202 (including any suitable refractive and/or diffractive elements) and one or more when constructed to focus light in any way onto the retina of a patient. The haptics 204 of the I 〇 L 200 within the anatomy of the eye are securely fixed at the time of implantation. Various embodiments of the inventive crystalloid delivery cassette 100 allow the IOL 200 to rest on a folding element 1 〇 8 of the floor of the aperture 104 of the crystal holder 102. "Bottom" means in the context of the crystal transport cassette 1 对应 that the surface corresponding to the [d〇wnward facing side] during the injection of the IOL 200 is generated regardless of the crystal transport cassette 100 The particular direction of being held, although the bottom is conventionally underneath the cymbal held by a person operating the crystal transport cassette 1〇〇. The folding elements 108 are assembled such that when the i-L 200 is slid through the folding elements 108, the IOL 200 is reassembled into at least one partially folded configuration. Examples of structures that can be used as the folded 4 element 1 〇 8 are described in U.S. Patent Nos. 5,947,976, 6, 083, 231, and 6, 143, 001, all of which are incorporated herein by reference. A variety of different folding devices. For example, one of the folding elements 108 can be an asymmetric ramp on the bottom of the aperture 104 to indicate folding in a particular direction. The folding elements 201231027 108 may also include raised cams (four) sed eams, strut (four) s), pegs and/or shelves to force the temples 2 to become a special direction when it is worn. When the folding elements are passed. When the mirrors 2, Putian 4 are not folded into the frame, the cams or the bars can keep the mirror body folded-folded. In the specific example of Fig. 1, the crystal delivery cartridge 100 includes a hole having a narrowed region 110 at a distal end of the aperture 1〇4. In the context of the crystal transport cassette, "near (pr〇ximai), meaning away from propelling the IOL 200 into the direction of the inside, and "distal" thinking of the IOL 200 advancement To the direction of the g, they conventionally correspond to a direction closer to or farther from the person operating the crystallographic transport cassette 100. The narrow diameter of the aperture 1〇4 causes the IOL 200 to fold by itself because of the I〇L 2〇〇 The plunger structure is advanced through the aperture. The folding structure 1〇8 indicates that the lens body 2〇2 and the temples 204 are folded into a desired folded configuration. The plunger 106 is used to advance the i〇l 2〇〇 Passing through the aperture 104. The plunger 106 can include a soft tip (S0ft tip) to reduce the monthly b-slope damage to the I 〇 L 2 , because the s-small I0L 200 is advanced through the aperture. In a specific example, the plunger 1 〇 6 includes a thumb slide Π 2 that is pushed distally by the operator to move the plunger 106. The alternative embodiment can use any of the cymbals to advance the Suitable techniques for the plunger include, for example, an injector that can include a thumb ring (Syringe_st) a plunger of y(4), a knob that is rotated to advance a plunger that is threadedly engaged with the bore 1, or even an electronically triggered electric injector. Generally slidably Advancing the I 〇 L2 穿过 through the hole 9 201231027 104 through the material folding element 丨 _ any manner is in principle compatible with a particular embodiment of the crystal transport benefit (10). The plunger 106 can also be biased in the direction or other (such as by placing - ramping in the hole 1〇4), and the plunger 106 can also have a tip that is offset from a central axis of the plunger 106 (having a tendency to push the IOL) 200 is preferentially modified in one direction.) At the distal end of the 5H crystal transport cassette 100 is an interface 114. The interface U4 is assembled to be connected to the injection port whereby the partially folded I 〇 L 2 The crucible is located approximately within the infusion cassette after delivery. Thus, for example, a delivery end of the crystal delivery cassette 100 can be partially inserted into a nozzle of the infusion cassette 'by thereby when the partially folded IOL 200 is delivered to the injection bowl, The nozzle maintains the state in which the IOL 200 is partially folded. The s-way interface 114 can also include generally the shape of at least a portion of the injection pocket, locking features [such as releasable hooks (easable hooks)) or sheets - Recesses' or other suitable receiving structures for receiving and placing the implants relative to the crystal transport cassette 1〇〇, corresponding to the 'tags' . To facilitate advancement of the IOL 200 in the injection bowl, the injection port can also be treated with a viscoelastic material, a liquid, and/or a smooth coating before or after attachment to the crystal delivery cassette 100.

Before the crystal transport cassette 100 is used to transport the cassette 200, the celebrity's IOahai IOL 200 is to be maintained in a rest position and preferably in an unfolded state. U.S. Patent No. 7,156,854 describes an intraocular crystal delivery system that has a stop that is frictionally engaged on a lid of the I 〇 10 201231027 delivery system to prevent an i在l Move within the delivery system. In order to maintain the IOL 200 in a stationary state before the IOL 200 is delivered to the injection port, a similar structure can likewise be placed on the top of the crystal delivery cassette 100. Alternatively, a stop member that is enlarged upward from the bottom of the crystal holder 102 can hold the I 〇 L 200 in place, and the sigma stop can be controlled by a control [such as a button (butt〇n ) or the use of a switch is unlocked. In general, any other structure or technique for maintaining the IO L 200 in a suitable stationary state may be suitably employed for use with the crystal delivery cartridge 100. A specific example of the crystal transport cassette 1 is depicted in Fig. 2. In the particular example depicted, the crystal delivery cartridge 100 includes a cap that holds the IOL 200 in place. In order to perform the crystal transport operation, the susceptor 116 is pressed downward to advance the 〇L 2 折叠 on the folded structure 1 〇 8 at the bottom of the crystal transport cassette 100. As shown by the arrows in Fig. 2, the susceptor 116 is then twisted to rotate the crystal, which is slid through the folding elements 1 〇 8 in order to fold the crystal. The pedestal 114 is removed to release the pleated IOL 200, and the plunger 〇6 slidably advances the folded IOL 200 through the aperture 1 through the apertures 108 and To the injection 匣. The use of a pedestal 114 and the plunger 1 〇 6 is only an alternative method of folding the crystal, and other alternative embodiments may involve different techniques to release the IO 200 and begin the folding process, such as by use. Pushing the sides of the IOL 200 to cause an initial folded side button. In general, any structure capable of sliding the I 〇 L 2 对抗 against the folded structure 108 in a desired configuration can be implemented in various 201231027 different embodiments of the present invention. Fig. 3 is a top view of a particular embodiment of a water crystal transfer case. In the particular case depicted, the crystal miscellaneous (4) includes a closure to form a hinged Hd around the aperture 104 of the aperture 104. The hinge cover may include additional components [co-operating with the folding members 1〇8 (such as the components that guide the mirror legs) to facilitate folding the I 〇 L 2 〇〇. The hinge cover is useful to allow the IOL 200 to be inserted into the crystal delivery cartridge 100 during the assembly process. Although the cover is shown as hinged, any suitable attachment method for a cover [such as a friction fit (frjcti〇n f|tting) or the like] can also be employed. The specific example of the depiction also shows thumb triggers that are pressed to release the IOL 200 from a stationary state. Fig. 4 is a flow chart showing an example of a method of transporting a crystal according to a specific embodiment of the present invention. In step 3, 2, a 〇L2 呈 is provided in a stationary state in a crystal delivery cassette 1 具有 having a folding member 108 at the bottom of the crystal transport cassette 100. In step 3〇4, an injector® is connected to the crystal delivery cassette 1〇〇. Depending on the particular operation of the crystal delivery cassette, the injector 匣 can also be coupled to the crystal delivery cassette 1 after other steps are performed. At step 306, the i 200 is released from a stationary state. Next, in step 308, to partially fold the IOL 200, the IOL 200 is slid through the folding elements 108. In one example, the IOL 200 can be released by removing a stop that is frictionally engaged at a top of the crystal delivery cartridge 100 in step 306, and in step 308 the IOL 200 can then be Remotely pushing the IOL 200 with a plunger 106 and sliding through the 12

S 201231027 Folding element 108. In another example, the IOL 200 can be released from the stationary state by pressing the I 〇 L 200 down the folding elements 1 〇 8 using a pedestal 114, and the I 〇 L 200 may be slid through the folding elements 108 by twisting the base 114 to rotate the I 〇 L 200 in step 308, after which the pedestal 114 may be removed from the OLED 200. In step 310, the IOL 200 is delivered from the crystal delivery cassette 100 to the injection cassette. In an example, the IOL 200 can be continuously delivered as part of the folding step 308. In another example, the I 〇 L 200 can be delivered in a separate step after the IOL 200 has been previously folded. In general, any method involving partial folding of the IOL 200 by sliding the IOL 200 through the folding element 108 prior to delivery to the injection cassette can be suitably employed for use with various embodiments of the present invention. . Although certain specific embodiments of the invention have been described above, these are provided for the purposes of illustration and description. Variations, changes, modifications, and alterations from the apparatus and methods disclosed above may be taken without departing from the scope of the invention as claimed. I: BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1A and FIG. 1B illustrate an intraocular lens delivery cassette in accordance with a particular embodiment of the present invention; and FIG. 2 shows an alternative crystal delivery cassette in accordance with another embodiment of the present invention; Figure 3 is a top level assembly view of a crystal transport case in accordance with a particular embodiment of the present invention; and 13 201231027 Figure 4 is a view showing the transport of an IOL from a crystal transport cassette to an injection port. A flow chart of an example method. [Main component symbol description] 100.. . Crystal transport box 102.. Aqua Crystal frame 104... Hole 106.. Plunger 108.. Folding element 110.. Narrow area 112.. Thumb slide 114.. Interface 116.. . Base 200.. . Intraocular lens 202.. . Mirror body 204.. . Mirror foot 300.. Flowchart 302, 304, 306, 308, 310 · ·.

S 14

Claims (1)

201231027 VII. Patent Application Range: 1. An intraocular lens (I〇L) delivery box for transporting an IOL to an injection sputum, comprising: a crystal frame for the glutinous IOL, comprising a hole a folding element in the crystal holder that is assembled to fold the I 〇L into a partially folded state as the I 〇L is slid through the aperture through the aperture; one is assembled to be movable An interface connected to an injection port, wherein when the connection a is connected to the injection, the interface is placed to deliver the IOL in the partially folded state within the injection port; and one is connected to The crystal holder is also assembled to push the I 〇L in the partially folded state through the aperture to deliver the 〇L to the plunger within the injection raft. 2. The I 〇 L transport case of claim i, wherein the folding elements comprise at least one ramp that is asymmetrically placed within the aperture. 3. The I 〇 L transport case of claim 1, wherein the folding element package 3 has at least a cam for folding the temple of the IOL. The invention discloses a patented "I 〇 L transport case" of the i-th item, wherein the folding elements comprise a rod that is assembled to keep the muscle partially folded. The IOL transport case of claim 1, wherein the IOL transport case further comprises a base that is assembled to maintain the IOL in a stationary state. 6. The I 〇 L transport case of claim 5, wherein the base is frictionally engaged on a top of the crystal holder. < 15 201231027 7. The muscle delivery cassette of claim 5, wherein the base pushes the IOL against the folding elements when pressed and slides the IOL through the folding elements when rotated. 8. 2 The application of the patent model of the muscle delivery box, wherein the plunger comprises - is used to turn into the residual plug through the aperture finger slider. 9. The IOL transport cassette of claim 1, wherein the interface includes a recess that substantially conforms to a shape of the injection pocket. 1) The I0L transport case of claim 1, wherein the interface includes a fixing member that is assembled to fix the injection g in place when the interface is connected to the injection E. 11. A method for transporting a mis-delivery-I0L to a --domain from a crystal, comprising: providing a crystal transport cassette comprising a crystal holder, a hole in the body frame, and a hole in the hole a folding member that folds the i〇L into a partially folded state when the loading IOL is slid through the folding member; removably attaching an injection port to the crystal transport cassette; The I 〇L is released from a stationary state in the transfer box; 'Moon 6 hunts through the XI to fold the Φ element to fold the IOL into a partially folded state; push S Hai into a partially folded state I0L passes through a distal end of the hole to the injection s; and the knife opens 5 the smectic crystal delivery box and the injection enthalpy. 12. The method of Section 7 of the patent application of the Shishen (7) Patent Park further includes treating the injection enthalpy with a viscoelastic material prior to pushing the IOL to the injection zone of 201231027. 13. The method of claim 11, wherein the step of sliding the IOL through the folding elements comprises using a plunger to push the IOL through the folding elements. 14. The method of claim 11, wherein: the step of releasing the IOL comprises pressing a base of the crystal delivery cassette to urge the IOL against the folding elements; and sliding the IOL through the folding The step of the component includes twisting the base to rotate the IOL through the folding elements. 15. The method of claim 11, wherein the step of removably attaching the injection cassette to the crystal delivery cassette comprises positioning the injection cassette at a position relative to the crystal delivery cassette. 17