TW200801200A - Methods for determining probability of an adverse or favorable reaction to a niacin receptor agonist - Google Patents
Methods for determining probability of an adverse or favorable reaction to a niacin receptor agonistInfo
- Publication number
- TW200801200A TW200801200A TW095129405A TW95129405A TW200801200A TW 200801200 A TW200801200 A TW 200801200A TW 095129405 A TW095129405 A TW 095129405A TW 95129405 A TW95129405 A TW 95129405A TW 200801200 A TW200801200 A TW 200801200A
- Authority
- TW
- Taiwan
- Prior art keywords
- gpr109a
- individual
- probability
- receptor
- amino acid
- Prior art date
Links
- 108700010041 Nicotinic acid receptor Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 239000000018 receptor agonist Substances 0.000 title abstract 2
- 229940044601 receptor agonist Drugs 0.000 title abstract 2
- 230000002411 adverse Effects 0.000 title 1
- 230000002349 favourable effect Effects 0.000 title 1
- 101000843809 Homo sapiens Hydroxycarboxylic acid receptor 2 Proteins 0.000 abstract 6
- 102100030643 Hydroxycarboxylic acid receptor 2 Human genes 0.000 abstract 6
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 150000007523 nucleic acids Chemical group 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 206010067484 Adverse reaction Diseases 0.000 abstract 1
- 230000006838 adverse reaction Effects 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 238000011010 flushing procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70737205P | 2005-08-10 | 2005-08-10 | |
| PCT/US2006/031032 WO2007021744A1 (en) | 2005-08-10 | 2006-08-09 | Methods for determining probability of an adverse or favorable reaction to a niacin receptor agonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200801200A true TW200801200A (en) | 2008-01-01 |
Family
ID=37496834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW095129405A TW200801200A (en) | 2005-08-10 | 2006-08-10 | Methods for determining probability of an adverse or favorable reaction to a niacin receptor agonist |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20090117559A1 (zh) |
| EP (1) | EP1924709A1 (zh) |
| TW (1) | TW200801200A (zh) |
| WO (1) | WO2007021744A1 (zh) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2331521T3 (es) | 2003-11-21 | 2010-01-07 | Arena Pharmaceuticals, Inc. | Derivados de acido 4-oxo-4,5-dihidro-furan-2-carboxilico y procedimientos de tratamiento de trastornos metabolicos relacionados del mismo. |
| AU2006247695B2 (en) | 2005-05-17 | 2012-08-09 | Merck Sharp & Dohme Corp. | Heterocycles as nicotinic acid receptor agonists for the treatment of dyslipidemia |
| US7737155B2 (en) | 2005-05-17 | 2010-06-15 | Schering Corporation | Nitrogen-containing heterocyclic compounds and methods of use thereof |
| US7750015B2 (en) | 2005-05-17 | 2010-07-06 | Schering Corporation | Nitrogen-containing heterocyclic compounds and methods of use thereof |
| WO2007087204A2 (en) | 2006-01-20 | 2007-08-02 | Schering Corpooration | Heterocycles as nicotinic acid receptor agonists for the treatment of dyyslipidemia |
| US20170042821A1 (en) * | 2007-07-01 | 2017-02-16 | Vitalis Llc | Combination tablet with chewable outer layer |
| WO2011057110A1 (en) * | 2009-11-06 | 2011-05-12 | Ruprecht-Karls-Universitat-Heidelberg | Gpr109a agonists for the treatment of cerebral ischemia |
| RU2612575C2 (ru) * | 2011-07-15 | 2017-03-09 | Конинклейке Филипс Н.В. | Обработка изображений для спектральной компьютерной томографии |
| GB2497766A (en) * | 2011-12-20 | 2013-06-26 | Gene Onyx Ltd | Snp analysis to determine efficacy of skin care product |
| CA2878625A1 (en) | 2012-07-11 | 2014-01-16 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5631734A (en) * | 1994-02-10 | 1997-05-20 | Affymetrix, Inc. | Method and apparatus for detection of fluorescently labeled materials |
| US6902902B2 (en) * | 2001-11-27 | 2005-06-07 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders |
| GB0319126D0 (en) * | 2003-08-14 | 2003-09-17 | Smithkline Beecham Corp | Chemical compounds |
-
2006
- 2006-08-09 US US11/990,240 patent/US20090117559A1/en not_active Abandoned
- 2006-08-09 WO PCT/US2006/031032 patent/WO2007021744A1/en not_active Ceased
- 2006-08-09 EP EP06789628A patent/EP1924709A1/en not_active Withdrawn
- 2006-08-10 TW TW095129405A patent/TW200801200A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1924709A1 (en) | 2008-05-28 |
| US20090117559A1 (en) | 2009-05-07 |
| WO2007021744A1 (en) | 2007-02-22 |
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