TW200801020A - Improved methods for preparing benzofused heteroaryl amide derivatives of thienopyridines - Google Patents
Improved methods for preparing benzofused heteroaryl amide derivatives of thienopyridinesInfo
- Publication number
- TW200801020A TW200801020A TW95132448A TW95132448A TW200801020A TW 200801020 A TW200801020 A TW 200801020A TW 95132448 A TW95132448 A TW 95132448A TW 95132448 A TW95132448 A TW 95132448A TW 200801020 A TW200801020 A TW 200801020A
- Authority
- TW
- Taiwan
- Prior art keywords
- preparing
- thienopyridines
- improved methods
- amide derivatives
- heteroaryl amide
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- -1 heteroaryl amide Chemical class 0.000 title 1
- 229940125670 thienopyridine Drugs 0.000 title 1
- 239000002175 thienopyridine Substances 0.000 title 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 108060006633 protein kinase Proteins 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000004037 angiogenesis inhibitor Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Landscapes
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention relates to methods for preparing compounds of formulae (I) and (XI): or pharmaceutically acceptable salts or solvates thereof. Compounds of the formula (I) and (XI) are useful as anti-angiogenesis agents and as agents for modulating and/or inhibiting the activity of protein kinases, thus providing treatments for cancer or other diseases associated with cellular proliferation mediated by protein kinases.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73199905A | 2005-09-02 | 2005-09-02 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200801020A true TW200801020A (en) | 2008-01-01 |
Family
ID=44764950
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW95132448A TW200801020A (en) | 2005-09-02 | 2006-09-01 | Improved methods for preparing benzofused heteroaryl amide derivatives of thienopyridines |
Country Status (1)
| Country | Link |
|---|---|
| TW (1) | TW200801020A (en) |
-
2006
- 2006-09-01 TW TW95132448A patent/TW200801020A/en unknown
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