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TW200640502A - Tablets with improved drug substance dispersibility - Google Patents

Tablets with improved drug substance dispersibility

Info

Publication number
TW200640502A
TW200640502A TW095106135A TW95106135A TW200640502A TW 200640502 A TW200640502 A TW 200640502A TW 095106135 A TW095106135 A TW 095106135A TW 95106135 A TW95106135 A TW 95106135A TW 200640502 A TW200640502 A TW 200640502A
Authority
TW
Taiwan
Prior art keywords
drug substance
tablets
improved drug
carrier
dispersibility
Prior art date
Application number
TW095106135A
Other languages
English (en)
Inventor
Nathalie Bernigal
Eric Garcia
Susanne Page
Joseph Tardio
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36406213&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TW200640502(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of TW200640502A publication Critical patent/TW200640502A/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW095106135A 2005-02-25 2006-02-23 Tablets with improved drug substance dispersibility TW200640502A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05101458 2005-02-25

Publications (1)

Publication Number Publication Date
TW200640502A true TW200640502A (en) 2006-12-01

Family

ID=36406213

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095106135A TW200640502A (en) 2005-02-25 2006-02-23 Tablets with improved drug substance dispersibility

Country Status (20)

Country Link
US (2) US20060193910A1 (zh)
EP (2) EP1855655A2 (zh)
JP (1) JP2008531509A (zh)
KR (1) KR20070094666A (zh)
CN (1) CN101128189A (zh)
AR (1) AR055561A1 (zh)
AU (1) AU2006218193A1 (zh)
BR (1) BRPI0606187A2 (zh)
CA (1) CA2598762A1 (zh)
CR (1) CR9292A (zh)
IL (1) IL185011A0 (zh)
MA (1) MA29268B1 (zh)
MX (1) MX2007009571A (zh)
NO (1) NO20074092L (zh)
NZ (1) NZ560232A (zh)
RU (1) RU2007129642A (zh)
TW (1) TW200640502A (zh)
UA (1) UA90708C2 (zh)
WO (1) WO2006089674A2 (zh)
ZA (1) ZA200706495B (zh)

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EP2207533B1 (en) * 2007-10-10 2021-01-06 Avantor Performance Materials, LLC Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof
US20100055180A1 (en) * 2007-10-10 2010-03-04 Mallinckrodt Baker, Inc. Directly Compressible Granular Microcrystalline Cellulose Based Excipient, Manufacturing Process and Use Thereof
DE102008047910A1 (de) 2008-09-19 2010-03-25 Molkerei Meggle Wasserburg Gmbh & Co. Kg Tablettierhilfsstoff auf Laktose- und Cellulosebasis
PE20160746A1 (es) * 2009-01-23 2016-08-01 Hoffmann La Roche Composicion farmaceutica que comprende aleglitazar
EP2722045B1 (en) 2009-11-18 2016-07-06 Helsinn Healthcare SA Compositions for treating centrally mediated nausea and vomiting
EP2361090B1 (en) 2009-11-18 2014-05-21 Helsinn Healthcare SA Compositions for treating centrally mediated nausea and vomiting
CN102641302B (zh) * 2011-02-18 2016-01-20 上海张江中药现代制剂技术工程研究中心 一种提高中药提取物浸膏粉软化点的方法
RU2468789C1 (ru) * 2011-05-04 2012-12-10 Федеральное государственное бюджетное учреждение науки Иркутский институт химии им. А.Е. Фаворского Сибирского отделения Российской академии наук (ИрИХ СО РАН) Средство для профилактики и лечения атеросклероза
CN104784239B (zh) * 2015-04-28 2017-12-26 新乡医学院第一附属医院 一种快速溶出的珍菊降压片及其制备工艺
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WO2017003137A1 (ko) * 2015-06-30 2017-01-05 (주)아모레퍼시픽 속붕해형 과립환 모발 세정용 조성물
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CN111548218A (zh) * 2020-04-27 2020-08-18 上海应用技术大学 一种通用型花肥速释片及其制备方法和应用
CN116602928A (zh) * 2023-06-30 2023-08-18 康普药业股份有限公司 一种甲苯磺酸艾多沙班组合物和制备方法
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Also Published As

Publication number Publication date
MX2007009571A (es) 2007-09-21
JP2008531509A (ja) 2008-08-14
ZA200706495B (en) 2008-10-29
NZ560232A (en) 2010-11-26
NO20074092L (no) 2007-09-04
IL185011A0 (en) 2007-12-03
CA2598762A1 (en) 2006-08-31
AR055561A1 (es) 2007-08-22
BRPI0606187A2 (pt) 2009-06-09
RU2007129642A (ru) 2009-03-27
CN101128189A (zh) 2008-02-20
WO2006089674A2 (en) 2006-08-31
MA29268B1 (fr) 2008-02-01
EP1855655A2 (en) 2007-11-21
CR9292A (es) 2010-04-21
WO2006089674A3 (en) 2007-02-08
EP2281556A1 (en) 2011-02-09
US20090304795A1 (en) 2009-12-10
US20060193910A1 (en) 2006-08-31
KR20070094666A (ko) 2007-09-20
AU2006218193A1 (en) 2006-08-31
UA90708C2 (ru) 2010-05-25

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