TW200637546A - Combination therapy - Google Patents
Combination therapyInfo
- Publication number
- TW200637546A TW200637546A TW094144909A TW94144909A TW200637546A TW 200637546 A TW200637546 A TW 200637546A TW 094144909 A TW094144909 A TW 094144909A TW 94144909 A TW94144909 A TW 94144909A TW 200637546 A TW200637546 A TW 200637546A
- Authority
- TW
- Taiwan
- Prior art keywords
- hydrochlorothiazide
- combination therapy
- telmisartan
- angiotensin
- treatment
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title 1
- RMMXLENWKUUMAY-UHFFFAOYSA-N telmisartan Chemical compound CCCC1=NC2=C(C)C=C(C=3N(C4=CC=CC=C4N=3)C)C=C2N1CC(C=C1)=CC=C1C1=CC=CC=C1C(O)=O RMMXLENWKUUMAY-UHFFFAOYSA-N 0.000 abstract 4
- JZUFKLXOESDKRF-UHFFFAOYSA-N Chlorothiazide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC2=C1NCNS2(=O)=O JZUFKLXOESDKRF-UHFFFAOYSA-N 0.000 abstract 3
- 229960002003 hydrochlorothiazide Drugs 0.000 abstract 3
- 239000005537 C09CA07 - Telmisartan Substances 0.000 abstract 2
- 239000002333 angiotensin II receptor antagonist Substances 0.000 abstract 2
- 229940126317 angiotensin II receptor antagonist Drugs 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 229960005187 telmisartan Drugs 0.000 abstract 2
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 230000036772 blood pressure Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Medicinal Preparation (AREA)
Abstract
A pharmaceutical composition comprising about 80 mg telmisartan and about 25 mg hydrochlorothiazide or about 160 mg telmisartan and about 50 mg hydrochlorothiazide for the treatment of hypertension in patients with an insufficient blood pressure reduction upon treatment either with an angiotensin II receptor antagonist, or a pharmaceutical composition of an angiotensin II receptor antagonist and a low dose of hydrochlorothiazide.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63706204P | 2004-12-17 | 2004-12-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW200637546A true TW200637546A (en) | 2006-11-01 |
Family
ID=35589356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW094144909A TW200637546A (en) | 2004-12-17 | 2005-12-16 | Combination therapy |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1827424A1 (en) |
| JP (1) | JP2008524136A (en) |
| KR (1) | KR20070097511A (en) |
| CN (1) | CN101080225A (en) |
| AR (1) | AR052052A1 (en) |
| AU (1) | AU2005315855A1 (en) |
| BR (1) | BRPI0519656A2 (en) |
| CA (1) | CA2589493A1 (en) |
| EA (1) | EA200701159A1 (en) |
| IL (1) | IL183944A0 (en) |
| NO (1) | NO20072325L (en) |
| PE (1) | PE20060768A1 (en) |
| TW (1) | TW200637546A (en) |
| UY (1) | UY29274A1 (en) |
| WO (1) | WO2006063737A1 (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7232828B2 (en) | 2002-08-10 | 2007-06-19 | Bethesda Pharmaceuticals, Inc. | PPAR Ligands that do not cause fluid retention, edema or congestive heart failure |
| US8637078B2 (en) | 2005-11-24 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Bilayer tablet comprising telmisartan and diuretic |
| EP1970053A1 (en) * | 2007-03-14 | 2008-09-17 | Boehringer Ingelheim Pharma GmbH & Co. KG | Pharmaceutical composition |
| CA2702904A1 (en) * | 2007-10-19 | 2009-04-23 | Otsuka Pharmaceutical Co., Ltd. | Matrix-type pharmaceutical solid preparation |
| EP2203158A4 (en) | 2007-10-30 | 2012-12-26 | Reddys Lab Ltd Dr | Pharmaceutical formulations comprising telmisartan and hydrochlorothiazide |
| WO2009115301A1 (en) | 2008-03-19 | 2009-09-24 | Ratiopharm Gmbh | Solid pharmaceutical composition comprising a non-peptide angiotensin ii receptor antagonist and a diuretic |
| KR20110038145A (en) | 2008-07-31 | 2011-04-13 | 다케다 야쿠힌 고교 가부시키가이샤 | Solid Pharmaceutical Compositions |
| GB0822170D0 (en) * | 2008-12-04 | 2009-01-14 | Arrow Int Ltd | Telmisartan with diuretic formulations |
| HRP20130557T1 (en) | 2009-06-19 | 2013-07-31 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of telmisartan |
| EP2448576A2 (en) * | 2009-07-02 | 2012-05-09 | Mahmut Bilgic | Solubility enhancing pharmaceutical composition |
| WO2011002425A2 (en) * | 2009-07-02 | 2011-01-06 | Bilgig Mahmut | Pharmaceutical composition increasing solubility and stability |
| TR200906506A2 (en) | 2009-08-24 | 2011-03-21 | Bi̇lgi̇ç Mahmut | Solid dosage forms containing telmisartan. |
| WO2011161123A2 (en) | 2010-06-21 | 2011-12-29 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Multilayer pharmaceutical tablet comprising telmisartan and a diuretic |
| EP2952196A4 (en) * | 2013-01-31 | 2016-08-03 | Sawai Seiyaku Kk | MULTILAYER TABLET CONTAINING TELMISARTAN AND HYDROCHLOROTHIAZIDE |
| ES2847904T3 (en) | 2013-07-23 | 2021-08-04 | Daiichi Sankyo Co Ltd | Medicine for the prevention or treatment of hypertension |
| CN106562973A (en) * | 2016-11-06 | 2017-04-19 | 成都先先先生物科技有限公司 | Anti-hypertension medicine compound preparation |
| CN107501192A (en) * | 2017-08-15 | 2017-12-22 | 中国科学院上海药物研究所 | The eutectic of Telmisartan and Hydrochioro |
| CN108653227A (en) * | 2018-08-09 | 2018-10-16 | 湖北舒邦药业有限公司 | A kind of Telmisartan hydrochlorothiazide tablets and preparation method thereof |
| EP4029867A1 (en) * | 2021-01-13 | 2022-07-20 | Alpha Cognition Inc. | Solid forms of galantamine benzoate gluconate |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4229085C2 (en) * | 1992-09-01 | 1996-07-11 | Boehringer Mannheim Gmbh | Elongated, divisible tablet |
| ES2298351T5 (en) * | 2002-01-16 | 2012-01-26 | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG | METHOD FOR PRODUCING A TWO-LAYER PHARMACEUTICAL TABLET THAT INCLUDES TELMISARTAN AND HYDROCLOROTIAZIDA. |
-
2005
- 2005-12-09 BR BRPI0519656-6A patent/BRPI0519656A2/en not_active Application Discontinuation
- 2005-12-09 EP EP05814002A patent/EP1827424A1/en not_active Withdrawn
- 2005-12-09 KR KR1020077016354A patent/KR20070097511A/en not_active Withdrawn
- 2005-12-09 WO PCT/EP2005/013224 patent/WO2006063737A1/en not_active Ceased
- 2005-12-09 EA EA200701159A patent/EA200701159A1/en unknown
- 2005-12-09 JP JP2007545905A patent/JP2008524136A/en active Pending
- 2005-12-09 CA CA002589493A patent/CA2589493A1/en not_active Abandoned
- 2005-12-09 CN CNA2005800434334A patent/CN101080225A/en active Pending
- 2005-12-09 AU AU2005315855A patent/AU2005315855A1/en not_active Abandoned
- 2005-12-15 PE PE2005001465A patent/PE20060768A1/en not_active Application Discontinuation
- 2005-12-16 TW TW094144909A patent/TW200637546A/en unknown
- 2005-12-16 AR ARP050105303A patent/AR052052A1/en unknown
- 2005-12-20 UY UY29274A patent/UY29274A1/en not_active Application Discontinuation
-
2007
- 2007-05-04 NO NO20072325A patent/NO20072325L/en not_active Application Discontinuation
- 2007-06-14 IL IL183944A patent/IL183944A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA200701159A1 (en) | 2007-12-28 |
| IL183944A0 (en) | 2007-10-31 |
| PE20060768A1 (en) | 2006-09-29 |
| CA2589493A1 (en) | 2006-06-22 |
| BRPI0519656A2 (en) | 2009-03-03 |
| EP1827424A1 (en) | 2007-09-05 |
| UY29274A1 (en) | 2006-07-31 |
| KR20070097511A (en) | 2007-10-04 |
| AU2005315855A1 (en) | 2006-06-22 |
| AR052052A1 (en) | 2007-02-28 |
| CN101080225A (en) | 2007-11-28 |
| WO2006063737A1 (en) | 2006-06-22 |
| NO20072325L (en) | 2007-07-06 |
| JP2008524136A (en) | 2008-07-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW200637546A (en) | Combination therapy | |
| IL273765A (en) | Combinations and modes of administration of therapeutic agents and combination therapy | |
| UA101309C2 (en) | Activin-actrii antagonists thereof and uses for increasing red blood cell levels | |
| AU2003210300A1 (en) | The use of tnf-alpha antagonist as drugs for the treatment of patients with sepsis and without suffering from total organ failure | |
| EP2248519A3 (en) | Non-mucoadhesive film dosage forms | |
| WO2004010975A3 (en) | Controlled drug delivery | |
| NO20072931L (en) | Improved dosing regimen of temozolomide for the treatment of cancer based on the patient's MGMT level | |
| WO2005048850A3 (en) | Systems and methods relating to associating a medical implant with a delivery device | |
| EP2335727A3 (en) | Combination treatment for non-hematologic malignancies using an anti-IGF-1R antibody | |
| LU93321I2 (en) | IBRUTINIB, OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | |
| WO2004087011A3 (en) | Therapeutic agent delivery device with controlled therapeutic agent release rates | |
| TW200631578A (en) | Methods and compositions using immunomodulatory compounds for treatment and management of central nervous system injury | |
| WO2007146426A3 (en) | Nanoshells for drug delivery | |
| WO2006060507A3 (en) | Compositions comprising immunomodulatory compounds and the use thereof for the treatment of immunodeficiency disorders | |
| WO2004064734A3 (en) | Combination therapies for the treatment of cancer | |
| CY1112184T1 (en) | PYRIDOXAMINE FOR USE IN TREATMENT OF DIABETIC Nephropathy in Type II Diabetes | |
| BRPI0413974A (en) | combination, method of treating cancer in a warm-blooded animal, pharmaceutical composition, and, use of a combination | |
| WO2007062093A3 (en) | Combination therapy for the treatment of cancer comprising a metalloprotease inhibitor | |
| GB2431346B (en) | A combination composition comprising paracetamol and ibuprofen | |
| MY137620A (en) | Therapeutic treatment | |
| BRPI0510895A (en) | 10-propargyl-10-deazaaminopterin pharmaceutical formulation for t-cell lymphoma treatment | |
| TW200503683A (en) | Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain | |
| TW200501953A (en) | Combination therapy for hypertension using lercanidipine and an angiotensin II receptor blocker | |
| TW200509909A (en) | Use of organic compounds | |
| WO2009134056A3 (en) | Pharmaceutical formulation |