TW200519119A - PENAM crystal and process for producing the same - Google Patents
PENAM crystal and process for producing the sameInfo
- Publication number
- TW200519119A TW200519119A TW093129591A TW93129591A TW200519119A TW 200519119 A TW200519119 A TW 200519119A TW 093129591 A TW093129591 A TW 093129591A TW 93129591 A TW93129591 A TW 93129591A TW 200519119 A TW200519119 A TW 200519119A
- Authority
- TW
- Taiwan
- Prior art keywords
- tmpb
- producing
- acetone
- alpha
- methyl
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 5
- WSHJJCPTKWSMRR-RXMQYKEDSA-N penam Chemical compound S1CCN2C(=O)C[C@H]21 WSHJJCPTKWSMRR-RXMQYKEDSA-N 0.000 title 1
- CSCPPACGZOOCGX-UHFFFAOYSA-N acetone Substances CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 8
- 125000001607 1,2,3-triazol-1-yl group Chemical group [*]N1N=NC([H])=C1[H] 0.000 abstract 2
- 101100029851 Arabidopsis thaliana PIP1-3 gene Proteins 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- -1 benzhydryl ester Chemical class 0.000 abstract 1
- 239000012141 concentrate Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/87—Compounds being unsubstituted in position 3 or with substituents other than only two methyl radicals attached in position 3, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/04—Preparation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003352723 | 2003-10-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TW200519119A true TW200519119A (en) | 2005-06-16 |
| TWI294880B TWI294880B (zh) | 2008-03-21 |
Family
ID=34431126
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW093129591A TW200519119A (en) | 2003-10-10 | 2004-09-30 | PENAM crystal and process for producing the same |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7547777B2 (zh) |
| EP (1) | EP1671975B1 (zh) |
| JP (1) | JP4841129B2 (zh) |
| KR (1) | KR101109177B1 (zh) |
| CN (1) | CN1863808B (zh) |
| AR (1) | AR046065A1 (zh) |
| AT (1) | ATE497965T1 (zh) |
| CA (1) | CA2540601C (zh) |
| DE (1) | DE602004031350D1 (zh) |
| ES (1) | ES2357839T3 (zh) |
| TW (1) | TW200519119A (zh) |
| WO (1) | WO2005035538A1 (zh) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200523264A (en) * | 2003-10-09 | 2005-07-16 | Otsuka Chemical Co Ltd | CMPB crystal and method for producing the same |
| US20060173177A1 (en) * | 2005-01-28 | 2006-08-03 | Gego Csaba L | Process for preparation of penam derivatives |
| JP4959385B2 (ja) * | 2007-03-09 | 2012-06-20 | 本田技研工業株式会社 | 車両用シート |
| US20150246931A1 (en) * | 2012-09-06 | 2015-09-03 | Hospira, Inc. | Process for the preparation of tazobactam |
| US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
| US20140274997A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Cephalosporin pharmaceutical compositions |
| UA121298C2 (uk) | 2013-03-15 | 2020-05-12 | Мерк Шарп І Доум Корп. | Антибіотична композиція на основі цефтолозану і тазобактаму |
| US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
| EP3043797B1 (en) | 2013-09-09 | 2020-04-08 | Merck Sharp & Dohme Corp. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
| US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
| US9433269B2 (en) | 2014-02-25 | 2016-09-06 | Oliver Joen-An Ma | Quick assembly methods and components for shade structures |
| CN105085544B (zh) * | 2015-08-19 | 2017-08-08 | 齐鲁天和惠世制药有限公司 | 一种他唑巴坦二苯甲酯的合成方法 |
| CN113861222A (zh) * | 2021-11-19 | 2021-12-31 | 山东安舜制药有限公司 | 一种采用新型催化剂合成去氧他唑巴坦二苯甲酯的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4891369A (en) * | 1986-12-03 | 1990-01-02 | Taiho Pharmaceutical Company, Limited | 2β-Substituted-methylpenicillanic acid derivatives, and salts and esters thereof |
| JP2603082B2 (ja) * | 1987-09-07 | 1997-04-23 | 大塚化学株式会社 | ペニシラン酸誘導体の製造法 |
| JP2599610B2 (ja) * | 1988-03-01 | 1997-04-09 | 大鵬薬品工業株式会社 | ２β―置換メチルペニシリン誘導体の製造法 |
| JP2602685B2 (ja) * | 1988-03-01 | 1997-04-23 | 大鵬薬品工業株式会社 | ２α−メチル−２β―（１，２，３−トリアゾール−１−イル）メチルペナム−３α−カルボン酸誘導体の製造法 |
| JP2648750B2 (ja) | 1988-03-02 | 1997-09-03 | 大塚化学株式会社 | β−ラクタム誘導体の製造方法 |
| EP0678095A1 (en) * | 1993-11-06 | 1995-10-25 | Taiho Pharmaceutical Co., Ltd. | Crystalline penicillin derivative, and its production and use |
| US6533787B1 (en) * | 2000-07-31 | 2003-03-18 | Sdgi Holdings, Inc. | Contourable spinal staple with centralized and unilateral prongs |
| JP3743823B2 (ja) * | 2000-08-11 | 2006-02-08 | 大塚化学ホールディングス株式会社 | ペニシリン結晶及びその製造法 |
| JP3743822B2 (ja) * | 2000-08-11 | 2006-02-08 | 大塚化学ホールディングス株式会社 | ペニシリン結晶及びその製造法 |
| JP3306473B1 (ja) * | 2001-05-01 | 2002-07-24 | 大塚化学株式会社 | β−ラクタム化合物の無水結晶及びその製造法 |
| JP2002338578A (ja) | 2001-05-14 | 2002-11-27 | Otsuka Chem Co Ltd | β−ラクタム化合物の水和物結晶 |
| JP4716708B2 (ja) * | 2004-10-28 | 2011-07-06 | 大塚化学株式会社 | ペナム化合物の製造方法 |
-
2004
- 2004-09-30 TW TW093129591A patent/TW200519119A/zh not_active IP Right Cessation
- 2004-10-08 WO PCT/JP2004/015299 patent/WO2005035538A1/ja not_active Ceased
- 2004-10-08 AT AT04792516T patent/ATE497965T1/de active
- 2004-10-08 US US10/574,279 patent/US7547777B2/en not_active Expired - Fee Related
- 2004-10-08 DE DE602004031350T patent/DE602004031350D1/de not_active Expired - Lifetime
- 2004-10-08 KR KR1020067006948A patent/KR101109177B1/ko not_active Expired - Fee Related
- 2004-10-08 CA CA2540601A patent/CA2540601C/en not_active Expired - Fee Related
- 2004-10-08 ES ES04792516T patent/ES2357839T3/es not_active Expired - Lifetime
- 2004-10-08 EP EP04792516A patent/EP1671975B1/en not_active Expired - Lifetime
- 2004-10-08 CN CN2004800292860A patent/CN1863808B/zh not_active Expired - Fee Related
- 2004-10-08 AR ARP040103657A patent/AR046065A1/es not_active Application Discontinuation
- 2004-10-12 JP JP2004297342A patent/JP4841129B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20070060559A1 (en) | 2007-03-15 |
| CA2540601C (en) | 2013-01-08 |
| JP4841129B2 (ja) | 2011-12-21 |
| EP1671975A4 (en) | 2007-03-14 |
| CN1863808B (zh) | 2013-06-05 |
| ES2357839T3 (es) | 2011-05-03 |
| KR20060120036A (ko) | 2006-11-24 |
| DE602004031350D1 (de) | 2011-03-24 |
| US7547777B2 (en) | 2009-06-16 |
| WO2005035538A1 (ja) | 2005-04-21 |
| CN1863808A (zh) | 2006-11-15 |
| EP1671975A1 (en) | 2006-06-21 |
| ATE497965T1 (de) | 2011-02-15 |
| CA2540601A1 (en) | 2005-04-21 |
| TWI294880B (zh) | 2008-03-21 |
| JP2005132839A (ja) | 2005-05-26 |
| AR046065A1 (es) | 2005-11-23 |
| HK1095142A1 (zh) | 2007-04-27 |
| KR101109177B1 (ko) | 2012-02-17 |
| EP1671975B1 (en) | 2011-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Annulment or lapse of patent due to non-payment of fees |