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TW200506054A - RNA interference in fish - Google Patents

RNA interference in fish

Info

Publication number
TW200506054A
TW200506054A TW093107906A TW93107906A TW200506054A TW 200506054 A TW200506054 A TW 200506054A TW 093107906 A TW093107906 A TW 093107906A TW 93107906 A TW93107906 A TW 93107906A TW 200506054 A TW200506054 A TW 200506054A
Authority
TW
Taiwan
Prior art keywords
fish
rna interference
organisms
shrimp
sirna
Prior art date
Application number
TW093107906A
Other languages
Chinese (zh)
Inventor
Michael Horne
Andrew Cartner Barnes
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TW200506054A publication Critical patent/TW200506054A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/60New or modified breeds of invertebrates
    • A01K67/61Genetically modified invertebrates, e.g. transgenic or polyploid
    • A01K67/65Genetically modified arthropods
    • A01K67/67Genetically modified crustaceans
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1131Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against viruses
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/40Fish
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/03Animal model, e.g. for test or diseases
    • A01K2267/0337Animal models for infectious diseases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering nucleic acids [NA]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Farming Of Fish And Shellfish (AREA)

Abstract

Gene silencing through siRNA has been shown to function in aquatic organisms such as shrimp. This technique can be applied to prevent or treat infections in these organisms by intracellular pathogens such as viruses.
TW093107906A 2003-03-24 2004-03-24 RNA interference in fish TW200506054A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0306715.4A GB0306715D0 (en) 2003-03-24 2003-03-24 Organic compounds

Publications (1)

Publication Number Publication Date
TW200506054A true TW200506054A (en) 2005-02-16

Family

ID=9955401

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093107906A TW200506054A (en) 2003-03-24 2004-03-24 RNA interference in fish

Country Status (3)

Country Link
GB (1) GB0306715D0 (en)
TW (1) TW200506054A (en)
WO (1) WO2004085645A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109689106A (en) * 2016-04-26 2019-04-26 微而广治疗有限公司 The composition and method for treating shrimp virus infection

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005005613A2 (en) 2003-07-02 2005-01-20 Medical University Of South Carolina Dsrna induced specific and non-specific immunity in crustaceans and other invertebrates and biodelivery vehicles for use therein
EP1789447B1 (en) 2004-08-16 2012-04-25 Immune Disease Institute, Inc. Method of delivering rna interference and uses thereof
ES2324263B1 (en) * 2007-07-13 2010-05-14 Inia (Instituto Nacional De Investigacion Y Tecnologia Agraria Y Alimentaria) SIRNA INHIBITORS OF THE VIRUS REPLICATION OF THE HEMORRAGICAL SEPTICEMY OF THE TRUCK (VHSV) AND APPLICATIONS.
WO2009098683A2 (en) 2008-02-04 2009-08-13 Ben-Gurion University Of The Negev Research And Development Authority Insulin-like gene in prawns and uses thereof
US8440878B2 (en) 2008-02-04 2013-05-14 Ben-Gurion University Of The Negev Research And Development Authority Insulin-like gene in prawns and uses thereof
CN102803516A (en) * 2009-06-19 2012-11-28 联邦科学与工业研究机构 Viral Assay
WO2012054919A2 (en) * 2010-10-22 2012-04-26 Donald Danforth Plant Science Center Control of pathogens and parasites
US8822427B2 (en) 2010-10-27 2014-09-02 Harrisvaccines Methods and compositions to protect aquatic invertebrates from disease
US10004797B2 (en) 2010-10-27 2018-06-26 Harrisvaccines, Inc. Method of rapidly producing improved vaccines for animals
EP2633049B1 (en) 2010-10-27 2018-10-10 Harrisvaccines Inc Methods and compositions to protect aquatic invertebrates from disease
US20120310140A1 (en) 2010-12-01 2012-12-06 Spinal Modulation, Inc. Directed delivery of agents to neural anatomy
EP3693465A1 (en) * 2019-02-05 2020-08-12 Pharmaq AS Novel fish coronavirus
CN110157743A (en) * 2019-05-28 2019-08-23 中国水产科学研究院黄海水产研究所 For striking the injection and application method of low turbot 14-3-3 gene expression
CN110684775A (en) * 2019-07-01 2020-01-14 上海海洋大学 A kind of Chinese mitten crab NKCC gene and its cloning method and expression analysis method
WO2021222943A1 (en) 2020-04-30 2021-11-04 Figene, Llc Immunotherapeutic methods and compositions for targeting cancer fibroblasts
CN112574989B (en) * 2020-12-10 2022-04-12 浙江省淡水水产研究所 shRNA for inhibiting reproduction of largemouth black bass rhabdovirus and application thereof
CN114958846A (en) * 2022-04-25 2022-08-30 浙江理工大学绍兴生物医药研究院有限公司 Preparation method of WSSV (white spot syndrome Virus) medicine capable of preventing and treating leukoderma
CN116064530B (en) * 2022-09-05 2025-09-12 中山大学 A grouper GU6-1 promoter mediating gene knockdown and its application
CN119061012B (en) * 2024-08-23 2025-10-17 中山大学 Shark EU6-1 promoter for mediating gene knockout and application thereof
CN119278889A (en) * 2024-12-09 2025-01-10 正大水产(湖州)有限公司 A method for breeding Macrobrachium rosenbergii

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003526367A (en) * 2000-03-16 2003-09-09 ジェネティカ インコーポレイテッド RNA interference method and RNA interference composition
NZ522045A (en) * 2000-03-30 2007-05-31 Whitehead Biomedical Inst RNA sequence-specific mediators of RNA interference

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109689106A (en) * 2016-04-26 2019-04-26 微而广治疗有限公司 The composition and method for treating shrimp virus infection

Also Published As

Publication number Publication date
GB0306715D0 (en) 2003-04-30
WO2004085645A1 (en) 2004-10-07

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